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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 9, 2024 | 12:39 PM IST
Medigef 250 Tablet is used to treat non-small cell lung cancer. It contains Gefitinib which works by inhibiting the growth and multiplication of cancer cells. In some cases, this medicine may cause side effects such as itching or skin rash, acne, nail problems, vomiting, diarrhoea, and loss of appetite. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Composition

GEFITINIB-250MG

Manufacturer/Marketer

Medion Biotech Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Medigef 250 Tablet

Medigef 250 Tablet belongs to the group of medicine called ‘anti-cancer’, primarily indicated in lung cancer treatment. Lung cancer is the uncontrolled growth of abnormal cells in one or both lungs. These abnormal cells do not carry out normal lung cell functions and do not develop into healthy lung tissue. In this disease, cells of the lung grow uncontrollably, and if not detected at an early stage may spread to other body parts, including the brain.

Medigef 250 Tablet contains 'Gefitinib' which belongs to the group of medicines known as 'kinase inhibitors'. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells.

Take Medigef 250 Tablet as prescribed by your doctor. You are suggested to take Medigef 250 Tablet as long as your doctor has prescribed it after checking your medical condition.  In some cases, you may experience certain common side effects such as itching or skin rash, acne, nail problems, vomiting, diarrhea, and loss of appetite. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Medigef 250 Tablet for as long as your doctor has prescribed. Do not take Medigef 250 Tablet if you are pregnant or planning for pregnancy as Medigef 250 Tablet causes serious birth defects. Medigef 250 Tablet should not be taken by breastfeeding mothers as it passes into breast milk and may cause a possible risk to the infant. Elderly people are more sensitive to medicine so they may adjust the dosage according to their condition. Avoid consuming alcohol along with Medigef 250 Tablet as it could lead to increased dizziness.

Uses of Medigef 250 Tablet

Treatment of Non-small cell lung cancer

Medicinal Benefits

Medigef 250 Tablet is indicated to the patients dealing with non-small cell lung cancer. Cancer of this type tends to spread quickly in other parts of the body. Medigef 250 Tablet travels through the bloodstream and effectively destroys cancerous cells of the lung and other parts of the body. Medigef 250 Tablet is a ' tyrosine kinase inhibitor (TKI)', that stops the uncontrolled growth and spread of cancerous cells.  It acts by stopping the abnormal protein action that is responsible for the multiplication of cancerous cells. Whenever a new healthy cell is formed, it undergoes a usual process of maturity. Cancerous cells form new cells more quickly, so Medigef 250 Tablet targets cancerous cells and blocks the action of Tyrosine kinase enzymes (responsible for causing cancer). It also decreases the blood supply to cancer tumors to slow down the growth of the tumor.  In this way, Medigef 250 Tablet stops the production, spread and growth of cancerous cells in the body.

Directions for Use

Medigef 250 Tablet can be taken without food on an empty stomach at least one or two hours before taking a meal. Swallow it as a whole with water; do not crush, break or chew it. Do not drink any liquid other than water to swallow the medicine.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Medigef 250 Tablet

  • Acne
  • Dry skin
  • Nausea
  • Vomiting
  • Diarrhoea
  • Loss of appetite
  • Itching or skin rash

Drug Warnings

Tell your doctor if you have liver or kidney disease, vision problems, breathing problems or taking any blood thinner like warfarin. Before undergoing any surgery, it is advised to tell the medical professional who performs the procedure about all the medicines you are taking. Some persons may experience diarrhoea as a side effect of Medigef 250 Tablet , so it is advised to drink a lot of water and tell your doctor in such a case. Inform your doctor if you notice any severe side effects of Medigef 250 Tablet , including shortness of breath, worsening cough, and other vision problems. You need to go to regular blood tests to check if this medicine is working fine for you.  Avoid high-fibre foods, raw fruits, cereals, vegetables, and drink lots of water as Medigef 250 Tablet may cause diarrhoea. 

Drug Interactions

Drug-Drug Interaction: Medigef 250 Tablet may have interaction with other anti-cancer medicine (Sorafenib and Paclitaxel), antibiotics (Neomycin), anti-seizure medicine (carbamazepine, phenytoin), NSAIDs (ibuprofen, naproxen), blood thinners (warfarin) and an antacid (Omeprazole).

Drug-Food Interaction: Avoid high-fiber foods, raw fruits, cereals, and vegetables, and drink lots of water as Medigef 250 Tablet may cause diarrhoea.

Drug-Disease Interaction: Tell your doctor if you have liver or kidney disease, vision problems, breathing problems.

Drug-Drug Interactions Checker List

  • SORAFENIB
  • PACLITAXEL
  • NEOMYCIN
  • CARBAMAZEPINE
  • PHENYTOIN
  • IBUPROFEN
  • NAPROXEN
  • WARFARIN
  • OMEPRAZOLE

Habit Forming

No

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles reduce fatigue, helps in weight loss, and give strength. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga and other relaxation techniques may also improve physical and mental health and may reduce your stress levels.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting helps in improving your health, mental ability and improves attention.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listen to soothing music.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing fibre help in better digestion. These include beans, peas, lentils, whole grains,  nuts, and seeds.
  • Avoid smoking and alcohol consumption.

Special Advise

  • It is suggested to avoid taking an antacid or stomach acid-reducing medicine within 6 hours after taking Medigef 250 Tablet as it may make the medicine less effective if taken simultaneously. 
  • Your doctor may suggest periodic liver function test to monitor the function of the liver due to the use of Medigef 250 Tablet .

Disease/Condition Glossary

Lung cancer: It happens when cells in the lung begin to grow in an uncontrolled manner. The most common form of lung cancer is non-small cell lung cancer (NSCLC). It happens when cells that form the lining of the lung start growing uncontrollably. Persons who smoke are at high risk of lung cancer. A common symptom of NSCLC is a cough that does not go easily followed by shortness of breath. Cancerous cells of the lung spread off and travel through the bloodstream to distant regions of the body and grow.

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption with Medigef 250 Tablet as it may increase the risk of side effects such as dizziness, drowsiness, or difficulty in concentrating.

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Pregnancy

Unsafe

Medigef 250 Tablet is restricted to use in pregnancy. A woman needs to have a negative pregnancy test before starting treatment with this medicine. It is better to use effective birth control methods to prevent pregnancy while taking this medicine or at least 6 months after taking the last dose of Medigef 250 Tablet .

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Breast Feeding

Unsafe

Medigef 250 Tablet should not be taken by breastfeeding mothers as it passes into breast milk and may cause a possible risk to the infant.

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Driving

Caution

It is not known if Medigef 250 Tablet may affect your driving ability or not. Drive only if you are physically stable and mentally focussed. If you experience drowsiness after taking this medication, you should not drive or operate any machinery or vehicles.

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Liver

Caution

Medigef 250 Tablet should be taken with caution in patients dealing with liver disease. The doctor may adjust the dose according to the medical condition of the patient.

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Kidney

Caution

Medigef 250 Tablet is safe to take by patients dealing with kidney disease as prescribed by their doctor. The doctor may adjust the dose according to the medical condition of the patient.

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Children

Unsafe

Medigef 250 Tablet is not recommended for children below 18 years as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

409, 4Th Floor, Devika Tower, Chander Nagar, Surya Nagar, Ghaziabad-201011, Uttar Pradesh, India
Other Info - MED1131

FAQs

Medigef 250 Tablet is used to treat non-small cell lung cancer.
Medigef 250 Tablet works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. Thereby, it prevents the spread of cancerous cells.
The most common sign of lung cancer is a cough that lasts long and gets worse with time. Sometimes, a patient may notice blood in the cough. Chest pain is also a sign of lung cancer followed by coughing.
It is suggested to avoid taking an antacid or stomach acid-reducing medicine within 6 hours after taking Medigef 250 Tablet as it may make the medicine less effective if taken simultaneously.
Medigef 250 Tablet is safe to be taken by a diabetic person. However, take Medigef 250 Tablet only after asking a doctor as they may adjust the dosing according to the patient's condition.

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