Matiz Plus Tablet belongs to a class of drugs called 'antispasmodics' primarily used to treat painful stomach cramps in the condition of irritable bowel syndrome (IBS) with bloating. Irritable bowel syndrome is a common disease that affects the large intestine. IBS is also known as spastic colon, irritable colon, spastic colitis, and mucous colitis. An irritable bowel syndrome is a group of intestinal symptoms that occur together.

Matiz Plus Tablet is a combination of two drugs: Mebeverine (antispasmodic) and Chlordiazepoxide (benzodiazepine). Mebeverine works by relaxing the intestinal muscle wall, thereby providing relief from painful muscle spasms. On the other hand, Chlordiazepoxide works by increasing a chemical messenger known as GABA (nerve-calming agent) activity in the brain, thereby decreasing nerve cells' abnormal activity. Thus, together it relaxes intestinal muscles, reduces stomach pain caused by spasms, cramps, gas formation, and bloating, and minimizes anxiety levels caused due to stomach discomfort. 

Take Matiz Plus Tablet as prescribed. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience drowsiness, dizziness, light-headedness, slurred speech, tiredness, lack of coordination, or difficulty in controlling movements. Most of these side effects of Matiz Plus Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Matiz Plus Tablet or any other medicines, please tell your doctor. Matiz Plus Tablet is not recommended for children below 18 years of age, as the safety and effectiveness were not established. You are advised not to take Matiz Plus Tablet if you are pregnant or planning for pregnancy as it may cause congenital disabilities (congenital disabilities). Matiz Plus Tablet may be excreted in breast milk. Therefore, avoid taking Matiz Plus Tablet if you are breastfeeding. Matiz Plus Tablet should be used with caution in the elderly as it may confuse them. Do not take Matiz Plus Tablet for longer than the prescribed period as it may cause dependence. Please do not stop taking Matiz Plus Tablet on your own as it might cause withdrawal symptoms. If you have vaginal bleeding or discharge, difficulty in urination, fever, constipation, blood in stools, myasthenia gravis (muscle weakness), anxiety disorders, depression, schizophrenia, manic depression, sleep apnoea (breathing stops and repeatedly starts during sleep), kidney or liver problems, inform your doctor before taking Matiz Plus Tablet .

Matiz Plus Tablet is a combination of two drugs: Mebeverine and Chlordiazepoxide to treat symptoms of irritable bowel syndrome (IBS) and painful stomach cramps. Mebeverine belongs to the class of antispasmodics that works by relieving contractions associated with smooth muscles of the stomach and intestine. Chlordiazepoxide is a benzodiazepine that increases GABA (nerve-calming agent) activity in the brain and decreases nerve cells' abnormal active cells. Thereby relaxing muscles and reducing anxiety caused due to painful stomach cramps. 

• Drowsiness
• Dizziness
• Light-headedness
• Slurred speech
• Tiredness
• Lack of coordination
• Difficulty in controlling movements

If you are known to be allergic to Matiz Plus Tablet or any other medicines, please tell your doctor. Matiz Plus Tablet is not recommended for children below 18 years of age, as the safety and effectiveness were not established. Avoid taking Matiz Plus Tablet if you are pregnant or planning for pregnancy as it may cause congenital disabilities (congenital disabilities). Matiz Plus Tablet may be excreted in breast milk. Therefore, avoid taking Matiz Plus Tablet if you are breastfeeding. Matiz Plus Tablet should be used with caution in the elderly as it may cause confusion in them. Do not take Matiz Plus Tablet for longer than the prescribed period as it may cause dependence. Please do not stop taking Matiz Plus Tablet on your own as it might cause withdrawal symptoms. If you cannot digest or tolerate any sugars, please tell your doctor as Matiz Plus Tablet contains sucrose and lactose. If you have vaginal bleeding or discharge, difficulty in urination, fever, constipation, blood in stools, myasthenia gravis (muscle weakness), anxiety disorders, depression, schizophrenia, manic depression, sleep apnoea (breathing stops and repeatedly starts during sleep), spinal or cerebral ataxia, kidney or liver problems, inform your doctor before taking Matiz Plus Tablet .

Drug-Drug Interaction: Matiz Plus Tablet may interact with pain killers (codeine, morphine), blood thinner (warfarin), benzodiazepine (diazepam), anticonvulsants (phenobarbitone, phenytoin), antibiotics (rifampicin), muscle relaxant (baclofen), antiparkinson drug (levodopa), antacids (cimetidine, omeprazole), heart-related medicines (digoxin), water pills (furosemide), bronchodilator (theophylline), anti-allergic drug (chlorphenamine).

Drug- Food Interaction: Avoid the intake of alcohol with Matiz Plus Tablet as it may increase drowsiness.

Drug-Disease Interaction: If you have vaginal bleeding or discharge, difficulty in urination, fever, constipation, blood in stools, myasthenia gravis (muscle weakness), anxiety disorders, depression, schizophrenia, manic depression, sleep apnoea (breathing stops and starts repeatedly during sleep), spinal or cerebral ataxia, kidney or liver problems, inform your doctor before taking Matiz Plus Tablet .

• CODEINE
• MORPHINE
• WARFARIN
• DIAZEPAM
• PHENOBARBITONE
• PHENYTOIN
• RIFAMPICIN
• BACLOFEN
• LEVODOPA
• CIMETIDINE
• OMEPRAZOLE
• DIGOXIN
• FUROSEMIDE
• THEOPHYLLINE
• CHLORPHENIRAMINE

• Eat smaller meals more often.
• Avoid smoking and alcohol consumption.
• Maintain a healthy weight by exercising regularly.
• Avoid carbonated and caffeinated beverages.
• Practise relaxation techniques and avoid stress by doing yoga or meditation.
• Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda.
• Avoid deep-fried and spicy foods.
• Foods containing probiotics may help in providing relief from gas and bloating.

Please consult a doctor if the symptoms persist or worsen after using Matiz Plus Tablet for more than 2 weeks.

Irritable bowel syndrome (IBS): It is a common disease that affects the large intestine. IBS is also known as irritable colon, spastic colon, spastic colitis, and mucous colitis. An irritable bowel syndrome is a group of intestinal symptoms that occur together. The exact cause is unknown, but common causes of IBS are acidity, stress, carbonated foods, and beverages, irregular hormone levels, certain food, and medications. Symptoms include abdominal pain, cramps, bloating, gas, constipation, and/or diarrhoea.