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Written By , M Pharmacy
Reviewed By , MPharma., PhD
Last Updated Jan 1, 2025 | 2:49 PM IST
Matiz Plus Tablet is used to treat painful stomach cramps in the condition of irritable bowel syndrome (IBS) with bloating. It contains Mebeverine and Chlordiazepoxide, which works by relaxing the intestinal muscle wall, thereby providing relief from painful muscle spasms. Also, it decreases the abnormal activity of nerve cells. Thus, it relaxes intestinal muscles, reduces stomach pain caused by spasms, cramps, gas formation, and bloating, and minimizes anxiety levels caused due to stomach discomfort. In some cases, it may cause side effects such as drowsiness, dizziness, light-headedness, slurred speech, tiredness, lack of coordination, or difficulty in controlling movements. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Manufacturer/Marketer :

Tas Med India Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Matiz Plus Tablet

Matiz Plus Tablet belongs to a class of drugs called 'antispasmodics' primarily used to treat painful stomach cramps in the condition of irritable bowel syndrome (IBS) with bloating. Irritable bowel syndrome is a common disease that affects the large intestine. IBS is also known as spastic colon, irritable colon, spastic colitis, and mucous colitis. An irritable bowel syndrome is a group of intestinal symptoms that occur together.

Matiz Plus Tablet is a combination of two drugs: Mebeverine (antispasmodic) and Chlordiazepoxide (benzodiazepine). Mebeverine works by relaxing the intestinal muscle wall, thereby providing relief from painful muscle spasms. On the other hand, Chlordiazepoxide works by increasing a chemical messenger known as GABA (nerve-calming agent) activity in the brain, thereby decreasing nerve cells' abnormal activity. Thus, together it relaxes intestinal muscles, reduces stomach pain caused by spasms, cramps, gas formation, and bloating, and minimizes anxiety levels caused due to stomach discomfort. 

Take Matiz Plus Tablet as prescribed. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience drowsiness, dizziness, light-headedness, slurred speech, tiredness, lack of coordination, or difficulty in controlling movements. Most of these side effects of Matiz Plus Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Matiz Plus Tablet or any other medicines, please tell your doctor. Matiz Plus Tablet is not recommended for children below 18 years of age, as the safety and effectiveness were not established. You are advised not to take Matiz Plus Tablet if you are pregnant or planning for pregnancy as it may cause congenital disabilities (congenital disabilities). Matiz Plus Tablet may be excreted in breast milk. Therefore, avoid taking Matiz Plus Tablet if you are breastfeeding. Matiz Plus Tablet should be used with caution in the elderly as it may confuse them. Do not take Matiz Plus Tablet for longer than the prescribed period as it may cause dependence. Please do not stop taking Matiz Plus Tablet on your own as it might cause withdrawal symptoms. If you have vaginal bleeding or discharge, difficulty in urination, fever, constipation, blood in stools, myasthenia gravis (muscle weakness), anxiety disorders, depression, schizophrenia, manic depression, sleep apnoea (breathing stops and repeatedly starts during sleep), kidney or liver problems, inform your doctor before taking Matiz Plus Tablet .

Uses of Matiz Plus Tablet

Treatment of Irritable bowel syndrome (IBS), Painful stomach cramps.

Medicinal Benefits

Matiz Plus Tablet is a combination of two drugs: Mebeverine and Chlordiazepoxide to treat symptoms of irritable bowel syndrome (IBS) and painful stomach cramps. Mebeverine belongs to the class of antispasmodics that works by relieving contractions associated with smooth muscles of the stomach and intestine. Chlordiazepoxide is a benzodiazepine that increases GABA (nerve-calming agent) activity in the brain and decreases nerve cells' abnormal active cells. Thereby relaxing muscles and reducing anxiety caused due to painful stomach cramps. 

Side Effects of Matiz Plus Tablet

  • Drowsiness
  • Dizziness
  • Light-headedness
  • Slurred speech
  • Tiredness
  • Lack of coordination
  • Difficulty in controlling movements

Directions for Use

Take Matiz Plus Tablet on an empty stomach preferably 20 minutes before a meal or as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are known to be allergic to Matiz Plus Tablet or any other medicines, please tell your doctor. Matiz Plus Tablet is not recommended for children below 18 years of age, as the safety and effectiveness were not established. Avoid taking Matiz Plus Tablet if you are pregnant or planning for pregnancy as it may cause congenital disabilities (congenital disabilities). Matiz Plus Tablet may be excreted in breast milk. Therefore, avoid taking Matiz Plus Tablet if you are breastfeeding. Matiz Plus Tablet should be used with caution in the elderly as it may cause confusion in them. Do not take Matiz Plus Tablet for longer than the prescribed period as it may cause dependence. Please do not stop taking Matiz Plus Tablet on your own as it might cause withdrawal symptoms. If you cannot digest or tolerate any sugars, please tell your doctor as Matiz Plus Tablet contains sucrose and lactose. If you have vaginal bleeding or discharge, difficulty in urination, fever, constipation, blood in stools, myasthenia gravis (muscle weakness), anxiety disorders, depression, schizophrenia, manic depression, sleep apnoea (breathing stops and repeatedly starts during sleep), spinal or cerebral ataxia, kidney or liver problems, inform your doctor before taking Matiz Plus Tablet .

Therapeutic Class

ANTISPASMODICS

Drug-Drug Interactions

verifiedApollotooltip
ChlordiazepoxideSodium oxybate
Critical
ChlordiazepoxideHydrocodone
Severe

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight by exercising regularly.
  • Avoid carbonated and caffeinated beverages.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda.
  • Avoid deep-fried and spicy foods.
  • Foods containing probiotics may help in providing relief from gas and bloating.

Habit Forming

Yes

How Matiz Plus Tablet Works

Matiz Plus Tablet is a combination of two drugs: Mebeverine (antispasmodic) and Chlordiazepoxide (benzodiazepine). Mebeverine works by relaxing the intestinal muscle wall, thereby providing relief from painful muscle spasms. On the other hand, Chlordiazepoxide works by increasing a chemical messenger known as GABA (nerve-calming agent) activity in the brain, thereby decreasing nerve cells' abnormal activity. Thus, together it relaxes intestinal muscles, reduces stomach pain caused by spasms, cramps, gas formation, and bloating, and minimizes anxiety levels caused due to stomach discomfort.

What if I have taken an overdose of Matiz Plus Tablet

Do not take more than the prescribed dose of Matiz Plus Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.
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Alcohol

Unsafe

Avoid alcohol consumption with Matiz Plus Tablet as it may increase drowsiness. Please consult a doctor before consuming alcohol while using Matiz Plus Tablet .

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Pregnancy

Unsafe

Matiz Plus Tablet is not recommended for pregnant women as it may cause harm the foetus. However, please consult a doctor if you are pregnant.

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Breast Feeding

Unsafe

Matiz Plus Tablet is not recommended for breastfeeding mothers as it is excreted in breast milk.

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Driving

Caution

Matiz Plus Tablet may cause drowsiness, dizziness or blurred vision in some people. So, drive only if you are alert and your vision is clear after taking Matiz Plus Tablet .

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Liver

Caution

Take Matiz Plus Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Matiz Plus Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Matiz Plus Tablet is not recommended for children below 18 years as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - MAT0182

Author Details

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FAQs

Matiz Plus Tablet is used to treat painful stomach cramps in the condition of irritable bowel syndrome (IBS) with bloating.
Matiz Plus Tablet contains Mebeverine and Chlordiazepoxide. Mebeverine belongs to the class of antispasmodics that relaxes the muscles in the walls of the intestine and provides relief from painful muscle spasms. Thus, it reduces stomach pain caused by spasm, cramps, and gas formation, bloating, and discomfort. Chlordiazepoxide works by increasing GABA (nerve-calming agent) activity in the brain and decreasing the abnormal activity of nerve cells. Thereby, relaxes muscles, increases its calming action and reduces anxiety.
Matiz Plus Tablet may cause dependence in patients especially when taken at high doses, for longer durations, or in patients with a history of drug abuse or alcoholism. Therefore, take Matiz Plus Tablet only as prescribed.
Dizziness may be a side effect of Matiz Plus Tablet . However, you are recommended to avoid driving if you feel dizzy after taking Matiz Plus Tablet .
Yes, Matiz Plus Tablet reduces stomach pain which is a symptom of irritable bowel syndrome. Matiz Plus Tablet contains Mebeverine, an antispasmodic agent which reduces spasms, cramps and stomach pain. However, please consult a doctor before taking Matiz Plus Tablet .
You are not recommended to take Matiz Plus Tablet with diazepam as co-administration of these two medicines may increase the risk of adverse effects such as drowsiness, dizziness, difficulty in concentrating, or confusion. However, please consult your doctor before taking Matiz Plus Tablet with other medicines.
Matiz Plus Tablet should be used with caution in elderly patients. Matiz Plus Tablet contains Chlordiazepoxide which may cause confusion in the elderly. However, please consult a doctor so that the dose may be adjusted appropriately.

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