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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:39 PM IST
Colospa X Tablet is used to treat painful stomach cramps in the condition of irritable bowel syndrome (IBS) with bloating. It contains Mebeverine and Chlordiazepoxide, which works by relaxing the intestinal muscle wall, thereby providing relief from painful muscle spasms. Also, it decreases the abnormal activity of nerve cells. Thus, it relaxes intestinal muscles, reduces stomach pain caused by spasms, cramps, gas formation, and bloating, and minimizes anxiety levels caused due to stomach discomfort. In some cases, it may cause side effects such as drowsiness, dizziness, light-headedness, slurred speech, tiredness, lack of coordination, or difficulty in controlling movements. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Abbott India Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Colospa X Tablet

Colospa X Tablet belongs to a class of drugs called 'antispasmodics' primarily used to treat painful stomach cramps in the condition of irritable bowel syndrome (IBS) with bloating. Irritable bowel syndrome is a common disease that affects the large intestine. IBS is also known as spastic colon, irritable colon, spastic colitis, and mucous colitis. An irritable bowel syndrome is a group of intestinal symptoms that occur together.

Colospa X Tablet is a combination of two drugs: Mebeverine (antispasmodic) and Chlordiazepoxide (benzodiazepine). Mebeverine works by relaxing the intestinal muscle wall, thereby providing relief from painful muscle spasms. On the other hand, Chlordiazepoxide works by increasing a chemical messenger known as GABA (nerve-calming agent) activity in the brain, thereby decreasing nerve cells' abnormal activity. Thus, together it relaxes intestinal muscles, reduces stomach pain caused by spasms, cramps, gas formation, and bloating, and minimizes anxiety levels caused due to stomach discomfort. 

Take Colospa X Tablet as prescribed. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience drowsiness, dizziness, light-headedness, slurred speech, tiredness, lack of coordination, or difficulty in controlling movements. Most of these side effects of Colospa X Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Colospa X Tablet or any other medicines, please tell your doctor. Colospa X Tablet is not recommended for children below 18 years of age, as the safety and effectiveness were not established. You are advised not to take Colospa X Tablet if you are pregnant or planning for pregnancy as it may cause congenital disabilities (congenital disabilities). Colospa X Tablet may be excreted in breast milk. Therefore, avoid taking Colospa X Tablet if you are breastfeeding. Colospa X Tablet should be used with caution in the elderly as it may confuse them. Do not take Colospa X Tablet for longer than the prescribed period as it may cause dependence. Please do not stop taking Colospa X Tablet on your own as it might cause withdrawal symptoms. If you have vaginal bleeding or discharge, difficulty in urination, fever, constipation, blood in stools, myasthenia gravis (muscle weakness), anxiety disorders, depression, schizophrenia, manic depression, sleep apnoea (breathing stops and repeatedly starts during sleep), kidney or liver problems, inform your doctor before taking Colospa X Tablet .

Uses of Colospa X Tablet

Treatment of Irritable bowel syndrome (IBS), Painful stomach cramps.

Medicinal Benefits

Colospa X Tablet is a combination of two drugs: Mebeverine and Chlordiazepoxide to treat symptoms of irritable bowel syndrome (IBS) and painful stomach cramps. Mebeverine belongs to the class of antispasmodics that works by relieving contractions associated with smooth muscles of the stomach and intestine. Chlordiazepoxide is a benzodiazepine that increases GABA (nerve-calming agent) activity in the brain and decreases nerve cells' abnormal active cells. Thereby relaxing muscles and reducing anxiety caused due to painful stomach cramps. 

Directions for Use

Take Colospa X Tablet on an empty stomach preferably 20 minutes before a meal or as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Colospa X Tablet

  • Drowsiness
  • Dizziness
  • Light-headedness
  • Slurred speech
  • Tiredness
  • Lack of coordination
  • Difficulty in controlling movements

Drug Warnings

If you are known to be allergic to Colospa X Tablet or any other medicines, please tell your doctor. Colospa X Tablet is not recommended for children below 18 years of age, as the safety and effectiveness were not established. Avoid taking Colospa X Tablet if you are pregnant or planning for pregnancy as it may cause congenital disabilities (congenital disabilities). Colospa X Tablet may be excreted in breast milk. Therefore, avoid taking Colospa X Tablet if you are breastfeeding. Colospa X Tablet should be used with caution in the elderly as it may cause confusion in them. Do not take Colospa X Tablet for longer than the prescribed period as it may cause dependence. Please do not stop taking Colospa X Tablet on your own as it might cause withdrawal symptoms. If you cannot digest or tolerate any sugars, please tell your doctor as Colospa X Tablet contains sucrose and lactose. If you have vaginal bleeding or discharge, difficulty in urination, fever, constipation, blood in stools, myasthenia gravis (muscle weakness), anxiety disorders, depression, schizophrenia, manic depression, sleep apnoea (breathing stops and repeatedly starts during sleep), spinal or cerebral ataxia, kidney or liver problems, inform your doctor before taking Colospa X Tablet .

Drug Interactions

Drug-Drug Interaction: Colospa X Tablet may interact with pain killers (codeine, morphine), blood thinner (warfarin), benzodiazepine (diazepam), anticonvulsants (phenobarbitone, phenytoin), antibiotics (rifampicin), muscle relaxant (baclofen), antiparkinson drug (levodopa), antacids (cimetidine, omeprazole), heart-related medicines (digoxin), water pills (furosemide), bronchodilator (theophylline), anti-allergic drug (chlorphenamine).

Drug- Food Interaction: Avoid the intake of alcohol with Colospa X Tablet as it may increase drowsiness.

Drug-Disease Interaction: If you have vaginal bleeding or discharge, difficulty in urination, fever, constipation, blood in stools, myasthenia gravis (muscle weakness), anxiety disorders, depression, schizophrenia, manic depression, sleep apnoea (breathing stops and starts repeatedly during sleep), spinal or cerebral ataxia, kidney or liver problems, inform your doctor before taking Colospa X Tablet .

Drug-Drug Interactions Checker List

  • CODEINE
  • MORPHINE
  • WARFARIN
  • DIAZEPAM
  • PHENOBARBITONE
  • PHENYTOIN
  • RIFAMPICIN
  • BACLOFEN
  • LEVODOPA
  • CIMETIDINE
  • OMEPRAZOLE
  • DIGOXIN
  • FUROSEMIDE
  • THEOPHYLLINE
  • CHLORPHENIRAMINE

Habit Forming

Yes

Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight by exercising regularly.
  • Avoid carbonated and caffeinated beverages.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda.
  • Avoid deep-fried and spicy foods.
  • Foods containing probiotics may help in providing relief from gas and bloating.

Special Advise

Please consult a doctor if the symptoms persist or worsen after using Colospa X Tablet for more than 2 weeks.

Disease/Condition Glossary

Irritable bowel syndrome (IBS): It is a common disease that affects the large intestine. IBS is also known as irritable colon, spastic colon, spastic colitis, and mucous colitis. An irritable bowel syndrome is a group of intestinal symptoms that occur together. The exact cause is unknown, but common causes of IBS are acidity, stress, carbonated foods, and beverages, irregular hormone levels, certain food, and medications. Symptoms include abdominal pain, cramps, bloating, gas, constipation, and/or diarrhoea.

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Alcohol

Unsafe

Avoid alcohol consumption with Colospa X Tablet as it may increase drowsiness. Please consult a doctor before consuming alcohol while using Colospa X Tablet .

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Pregnancy

Unsafe

Colospa X Tablet is not recommended for pregnant women as it may cause harm the foetus. However, please consult a doctor if you are pregnant.

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Breast Feeding

Unsafe

Colospa X Tablet is not recommended for breastfeeding mothers as it is excreted in breast milk.

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Driving

Caution

Colospa X Tablet may cause drowsiness, dizziness or blurred vision in some people. So, drive only if you are alert and your vision is clear after taking Colospa X Tablet .

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Liver

Caution

Take Colospa X Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Colospa X Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Colospa X Tablet is not recommended for children below 18 years as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - COL0934

Author Details

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FAQs

Colospa X Tablet is used to treat painful stomach cramps in the condition of irritable bowel syndrome (IBS) with bloating.
Colospa X Tablet contains Mebeverine and Chlordiazepoxide. Mebeverine belongs to the class of antispasmodics that relaxes the muscles in the walls of the intestine and provides relief from painful muscle spasms. Thus, it reduces stomach pain caused by spasm, cramps, and gas formation, bloating, and discomfort. Chlordiazepoxide works by increasing GABA (nerve-calming agent) activity in the brain and decreasing the abnormal activity of nerve cells. Thereby, relaxes muscles, increases its calming action and reduces anxiety.
Colospa X Tablet may cause dependence in patients especially when taken at high doses, for longer durations, or in patients with a history of drug abuse or alcoholism. Therefore, take Colospa X Tablet only as prescribed.
Dizziness may be a side effect of Colospa X Tablet . However, you are recommended to avoid driving if you feel dizzy after taking Colospa X Tablet .
Yes, Colospa X Tablet reduces stomach pain which is a symptom of irritable bowel syndrome. Colospa X Tablet contains Mebeverine, an antispasmodic agent which reduces spasms, cramps and stomach pain. However, please consult a doctor before taking Colospa X Tablet .
You are not recommended to take Colospa X Tablet with diazepam as co-administration of these two medicines may increase the risk of adverse effects such as drowsiness, dizziness, difficulty in concentrating, or confusion. However, please consult your doctor before taking Colospa X Tablet with other medicines.
Colospa X Tablet should be used with caution in elderly patients. Colospa X Tablet contains Chlordiazepoxide which may cause confusion in the elderly. However, please consult a doctor so that the dose may be adjusted appropriately.

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