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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 11, 2024 | 2:34 PM IST
Mage 2 Tablet is used to treat type 2 diabetes. It contains Repaglinide which works by increasing the amount of insulin released by the pancreas. In some cases, this medicine may cause side effects such as headache, stomach pain, common cold, diarrhoea, joint pain and back pain. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Composition

REPAGLINIDE-2MG

Manufacturer/Marketer

Eris Life Sciences Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Mage 2 Tablet

Mage 2 Tablet belongs to the category of medicines called 'anti-diabetic primarily used for the management and treatment of type 2 diabetes, especially in persons whose sugar levels are too high and cannot be only controlled by dieting and exercising. Type 2 diabetes is a condition that occurs when there is either less insulin or available insulin is not properly utilized by our body cells for lowering raised blood glucose. It is the most common type of diabetes, accounting for around 90% of total diabetes cases found commonly in middle-aged people. So it is also called adult-onset diabetes or non-insulin-dependent diabetes mellitus (NIDDM).

Mage 2 Tablet contains 'Repaglinide', a meglitinide that works by increasing the amount of insulin released by the pancreas. It starts acting so quickly on controlling blood sugar levels immediately after a meal. Mage 2 Tablet may be advised with or without other medications along with diet and exercise to control blood sugar levels. 

Your doctor will decide what dose should be taken for better advice, and it can change timely depending upon your condition. In some cases, you may experience headache, stomach pain, a sign of a common cold, diarrhoea, joint pain and back pain. Most of these side effects of Mage 2 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

You should not take Mage 2 Tablet if you have type 1 diabetes mellitus, renal impairment, metabolic acidosis, diabetic ketoacidosis (excess acids in your blood), or severe kidney or liver disease. Please inform your doctor if you have any heart disease, are planning to get pregnant, or are breastfeeding. Mage 2 Tablet should not be stopped even if you feel better, without consulting your doctor as your sugar level keeps changing. If you stop taking Mage 2 Tablet abruptly, it may increase your sugar levels, which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy), and nerve damage (neuropathy).

Uses of Mage 2 Tablet

Treatment of Type 2 Diabetes Mellitus.

Medicinal Benefits

Mage 2 Tablet belongs to the group of medicines called “anti-diabetic” indicated in the treatment of type 2 diabetes or non-insulin-dependent diabetes (NIDDM). This medicine is primarily prescribed to persons whose blood sugar levels are high and is even not controlled by diet and exercise alone. Mage 2 Tablet consists of Repaglinide belongs to a class of meglitinide that works by increasing the amount of insulin released by the pancreas. It starts acting so quickly on controlling blood sugar levels immediately after a meal. Mage 2 Tablet may be advised with or without other medications along with diet and exercise to control blood sugar levels. 

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Mage 2 Tablet

  • Headache
  • Stomach pain
  • Sign of a common cold
  • Diarrhoea
  • Joint pain
  • Back pain

Drug Warnings

Mage 2 Tablet should not be used in patients with type 1 diabetes or with diabetic ketoacidosis (in this condition, there is too much lactic acid accumulated in the blood). Inform your doctor if you take other antidiabetic drugs to adjust the dosage of Mage 2 Tablet accordingly. Do not abruptly stop taking Mage 2 Tablet midway if the doctor did not advise you. Mage 2 Tablet may cause hypoglycaemia (low blood sugar), hence it is advised to make healthy food with enough calories and avoid heavy exercises.  Mage 2 Tablet is not recommended for use during pregnancy and breastfeeding. Your doctor may advise alternate medications to control your diabetic condition in such cases. Mage 2 Tablet is not recommended for people younger than 18 years or over 75 years of age.  Before you start taking Mage 2 Tablet , tell your doctor if you have serious heart disease or if you have had a stroke, low blood pressure (hypotension), and severe liver or kidney disease. Avoid alcohol intake while using Mage 2 Tablet since it may increase the risk of lactic acidosis. 

Drug Interactions

Drug-Drug Interactions: Mage 2 Tablet may interact with insulin, high blood pressure-lowering pills (amlodipine, metoprolol, atenolol, propranolol, bisoprolol, benazepril, enalapril), water pills/diuretics (hydrochlorothiazide, furosemide), heart failure-related medicines (digoxin), painkiller (aspirin), a medicine used to treat cancer (octreotide, danazol), antibiotics (clarithromycin, trimethoprim, rifampicin), antifungal (itraconazole, ketoconazole), a medicine used to treat high blood fats (gemfibrozil), a medicine used to suppress the immune system (ciclosporin) steroids (prednisolone), medicine prevents blood clots (clopidogrel), a medicine used to treat epilepsy (phenytoin, carbamazepine, phenobarbital), thyroid hormones.

Drug-Food Interactions: Taking Mage 2 Tablet with St. John’s wort (herbal medicine) and alcoholic beverages may increase the risk of a rare but serious and potentially life-threatening condition known as lactic acidosis (build-up of lactic acid in the blood) hypoglycemia.

Drug-Disease Interactions: Mage 2 Tablet should be avoided in patients with kidney problems, liver problems, cardiovascular disease (heart-related issues), and low blood sugar levels (hypoglycemia) may worsen the condition.

Drug-Drug Interactions Checker List

  • AMLODIPINE
  • METOPROLOL
  • ATENOLOL
  • PROPRANOLOL
  • BISOPROLOL
  • BENAZEPRIL
  • ENALAPRIL
  • FUROSEMIDE
  • DIGOXIN
  • ASPIRIN
  • OCTREOTIDE
  • DANAZOL
  • CLARITHROMYCIN
  • TRIMETAPHAN
  • RIFAMPICIN
  • ITRACONAZOLE
  • KETOCONAZOLE
  • GEMFIBROZIL
  • CICLOSPORIN
  • PREDNISOLONE
  • CLOPIDOGREL
  • PHENYTOIN
  • CARBAMAZEPINE
  • PHENOBARBITAL

Habit Forming

No

Diet & Lifestyle Advise

  • Fill your half plate with starchy veggies, a quarter with proteins, and a quarter with whole grain.
  • Eat at regular intervals. Do not take the long gap between a meal or snack.
  • Monitor your blood sugar level regularly, especially when there are a lot of fluctuations.
  • Invest in at least 150 min of moderate-intensity physical activity and 15 minutes of high-intensity exercise every week.
  • Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replace refined carbohydrates containing whole-grain foods and increase intake of fruits and veggies and other fibre-enriched foods.
  • Reduce intake of saturated fat (or hidden fats) in food like chips, crisps, pastries, biscuits, and samosas. Choose omega 3 fatty acid-containing oils for daily cooking. You may use palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil for frying.
  • Do not take stress as it may elevate your blood sugar level. You may adopt stress management techniques like mindfulness, yoga, or meditation to control stress-related blood sugar changes.
  • Opt for low-fat dairy products (low-fat yoghurt, fat-free milk, and cheese, etc.).
  • Keep your blood pressure as normal (120/80) as possible as it reduces the risk of cardiovascular diseases in diabetes patients.

Special Advise

  •  
  • It is advised to monitor your blood sugar levels regularly.
  • Keep taking the drug even if you think your blood sugar levels are under control. If you miss a dose, do not take a larger dose, consult your treating physician for advice.
  • Take short, frequent meals, avoid prolonged fasting when taking this drug. Beware of hypoglycaemia symptoms include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc. Whenever you experience the above-mentioned symptoms, immediately consume 5-6 candies or 3 glucose biscuits or 3 teaspoons of honey/sugar and get in touch with your physician. Make sure to carry these with you at all times, especially for long travels. 
  • Avoid drinking alcohol while on this drug as it increases the risk of hypoglycaemia (decrease in blood sugar which might be fatal in some cases) and lactic acidosis (when the lactic acid increases in the body, impacting the functioning of various organs in the body).
  • Try to quit smoking and reduce carbohydrate-rich food like potato, rice, mangoes, bread, sugar etc.
  • Remember, lifestyle modifications are the most important step in controlling blood sugar levels.

Disease/Condition Glossary

Diabetes mellitus 2, also known as adult-onset diabetes, is a metabolic disease that causes high blood sugar levels. It is type 2 diabetes and occurs when the insulin (a hormone produced by the beta cells of the pancreas) is resistant in breaking the glucose to produce energy (insulin resistance) or the pancreas (an organ behind the stomach) produce little or no insulin at all. This disease mostly occurs in people aged above 40 years, but can also occur in childhood based on the risk factors. The treatment includes oral glucose-lowering medicines and insulin shots.

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Mage 2 Tablet to avoid unpleasant side-effects.

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Pregnancy

Caution

Mage 2 Tablet is pregnancy category C drug. As the data around the use of Mage 2 Tablet in pregnant women is limited, the use of Mage 2 Tablet in pregnancy is restricted. It is highly recommended to consult your doctor before taking this drug in case you are pregnant.

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Breast Feeding

Caution

It is unknown whether Mage 2 Tablet is excreted in human milk. Please consult a doctor before using Mage 2 Tablet while breastfeeding.

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Driving

Caution

Your driving may be affected if your blood sugar levels are too high or too low. Do not drive or operate machinery if you also experience blurred vision, dizziness or drowsiness due to extremely low or high blood sugar.

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Liver

Caution

Mage 2 Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor. However, Mage 2 Tablet is not recommended for severe liver disease.

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Kidney

Caution

Mage 2 Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor. However, Mage 2 Tablet is not recommended for severe kidney disease.

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Children

Unsafe

The safety and efficacy of Mage 2 Tablet in children have not been established. Mage 2 Tablet is not recommended in children.

Country of origin

India

Manufacturer/Marketer address

8th Floor, Commerce House IV, Prahladnagar, Ahmedabad ? 380015 Gujarat, India.
Other Info - MAG0424

Author Details

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FAQs

Mage 2 Tablet is used for the management and treatment of type 2 diabetes, especially in persons whose sugar levels are too high and cannot be only controlled by dieting and exercising.
Mage 2 Tablet contains Repaglinide that works by increases the amount of insulin released by the pancreas which prevents blood glucose from rising very high after meals.
Hypoglycemia refers to low blood sugar levels, and it is one of the side effects of Mage 2 Tablet . Hypoglycemia can occur if you miss or delay your food, drink alcohol, over-exercise, or take other antidiabetic medicine along with this medicine. It is important to monitor blood sugar levels regularly.
Type-2 diabetes generally does not affect healthy children and teens, but it may affect children who are obese, which is also known as Childhood Obesity.
If a person is getting unusually thrust or passing urine frequently more than normal while taking Mage 2 Tablet , they should tell it to their doctor as it may be a sign that there is too much sugar in their blood and treatment needs to be adjusted. It may also because of dehydration as Mage 2 Tablet can lead to loss of fluids. Increase intake of fluids, if even then you feel thirsty, please consult your doctor.
Your doctor may suggest you go for a regular test for sugar (glucose) in your blood or urine to monitor if diabetes has controlled or not.
Diabetes is a chronic medical condition that means lifelong, so its treatment should also continue for the whole life, so keep taking Mage 2 Tablet unless your doctor advises you to stop the medicine.
Mage 2 Tablet should be used with caution in heart, kidney or liver diseases, breathing problems, blood disorders, dehydration, alcohol use, foot ulcers, nerve damage, low blood pressure and severe infections. Mage 2 Tablet is contraindicated in patients with renal impairment and diabetic ketoacidosis.
If you feel that your blood sugar level is going down and you are feeling weak, immediately eat sugar candies or drink sugary beverages. It will help to balance the blood sugar level in your body. So, it is advisable to keep sugar candies with you.
Mage 2 Tablet is pregnancy category C drug. As the data around the use of Mage 2 Tablet in pregnant women is limited, the use of Mage 2 Tablet in pregnancy is restricted. It is highly recommended to consult your doctor before taking this drug in case you are pregnant.
Repaglinide begins working 30 minutes after it is taken.
Repaglinide is rapidly absorbed and has a half-life of less than 60 minutes.
You are recommended not to consume alcohol along with the Mage 2 Tablet to avoid unpleasant side effects. Also, alcohol may affect blood glucose levels in patients with diabetes.
Mage 2 Tablet may be used as monotherapy (supplemental to exercise and diet control) or combined with other antihyperglycemic agents. However, it should only be taken if prescribed by the doctor.
No, you should not breastfeed while taking Mage 2 Tablet without consulting your doctor. Although it is unlikely to pass into breast milk significantly, it can cause low blood sugar in breastfed infants.
Taking clopidogrel and Mage 2 Tablet together may cause a drop in blood sugar levels, known as hypoglycemia. If you are taking clopidogrel and need to take Mage 2 Tablet , let your doctor know; your healthcare provider may guide an alternative approach.
Mage 2 Tablet should be taken before or up to 30 minutes before each main meal.
Do not use this medicine if you are under 18 years of age.
No, it is a prescription medication and should be taken only if prescribed by the doctor.
Common side effects of Mage 2 Tablet may include headache, stomach pain, a sign of a common cold, diarrhoea, joint pain, and back pain. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.
Do not take other medicines when you take Mage 2 Tablet unless they have been discussed with your doctor. Limit or avoid the consumption of alcohol. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with repaglinide.
Store in a cool and dry place away from sunlight. Keep Mage 2 Tablet out of sight and reach of children.
Mage 2 Tablet contains Mage 2 Tablet , an antidiabetic drug in the class of medications known as meglitinides.
No, it is not recommended to treat type 1 diabetes mellitus.
Mage 2 Tablet should be continued even if you feel better, without consulting your doctor as your sugar level keeps changing. If you stop taking Mage 2 Tablet abruptly, it may increase your sugar levels, which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy), and nerve damage (neuropathy).
Diabetes mellitus 2, also known as adult-onset diabetes, is a metabolic disease that causes high blood sugar levels.
Your driving ability may be affected if your blood sugar levels are too high or too low. Do not drive or operate machinery if you also experience blurred vision, dizziness or drowsiness due to extremely low or high blood sugar.

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