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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 9:31 AM IST

Lupitum 125mg Injection 1gm is an antibiotic medicine used to treat bacterial infections such as gynaecological infections, urinary tract infections, post-operative infections, meningitis (inflammation of brain and spinal cord), biliary infections, septicaemia, infections in immune-compromised patients, skin and soft tissue infections, and bone and joint infections. It contains Cefoperazone and Tazobactam. Cefoperazone kills bacteria by inhibiting nucleopeptide synthesis in the bacterial cell wall. Tazobactam reduces bacterial resistance and enhances the activity of Cefoperazone against bacteria. Together, they help to treat bacterial infections.

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Prescription drug

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Manufacturer/Marketer :

Lupin Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Lupitum 125mg Injection 1gm

Lupitum 125mg Injection 1gm belongs to the group of medicines called antibiotics used to treat bacterial infections such as gynaecological infections, urinary tract infections, post-operative infections, meningitis (inflammation of brain and spinal cord), biliary infections, septicaemia, infections in immune-compromised patients, skin and soft tissue infections, and bone and joint infections.

Lupitum 125mg Injection 1gm contains Cefoperazone and Tazobactam. Cefoperazone kills bacteria by inhibiting nucleopeptide synthesis in the bacterial cell wall. Tazobactam reduces bacterial resistance and enhances the activity of Cefoperazone against bacteria. Together, Lupitum 125mg Injection 1gm helps to treat bacterial infections.

In some cases, Lupitum 125mg Injection 1gm may cause side effects such as pain and inflammation at the site of injection, nausea, vomiting, and indigestion. These side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.

Consult the doctor if you are pregnant or breastfeeding. The safety and efficacy of Lupitum 125mg Injection 1gm in children below 12 years has not been established. Keep the doctor informed about your health condition and medications to rule out any unpleasant side effects/interactions.

Uses of Lupitum 125mg Injection 1gm

Treatment of Bacterial infections

Medicinal Benefits

Lupitum 125mg Injection 1gm belongs to the group of medicines called antibiotics used to treat bacterial infections such as gynaecological infections, urinary tract infections, post-operative infections, meningitis (inflammation of brain and spinal cord), biliary infections, septicaemia, infections in immune-compromised patients, skin and soft tissue infections, bone and joint infections, and gonorrhoea. Lupitum 125mg Injection 1gm contains Cefoperazone (cephalosporin antibiotic) and Tazobactam (beta-lactamase inhibitor). Cefoperazone kills the bacteria by inhibiting nucleopeptide synthesis in the bacterial cell wall. Tazobactam reduces bacterial resistance and enhances the activity of Cefoperazone against bacteria. Together, Lupitum 125mg Injection 1gm helps to treat bacterial infections.

Side Effects of Lupitum 125mg Injection 1gm

  • Pain and inflammation at the site of injection
  • Nausea
  • Vomiting
  • Indigestion

Directions for Use

Lupitum 125mg Injection 1gm will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not receive Lupitum 125mg Injection 1gm if you are allergic to any of its components. Consult the doctor if you are pregnant or breastfeeding. The safety and efficacy of Lupitum 125mg Injection 1gm in children below 12 years has not been established. Let the doctor know if you take prescription/non-prescription medicines, including supplements or herbal products.

Therapeutic Class

ANTIBIOTICS

Drug-Drug Interactions

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CefoperazoneBCG vaccine
Critical
CefoperazoneRifampicin
Severe

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Include whole grains, fruits, and vegetables in your diet. 
  • Taking probiotics after antibiotics and eating high-fibre and prebiotic foods may help reduce side effects and support digestion.
  • Exercising regularly helps in improving overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress.
  • Avoid processed and fried food.

Habit Forming

No

How Lupitum 125mg Injection 1gm Works

Lupitum 125mg Injection 1gm contains Cefoperazone and Tazobactam. Cefoperazone kills bacteria by inhibiting nucleopeptide synthesis in the bacterial cell wall. Tazobactam reduces bacterial resistance and enhances the activity of Cefoperazone against bacteria. Together, Lupitum 125mg Injection 1gm helps to treat bacterial infections.

What if I have taken an overdose of Lupitum 125mg Injection 1gm

As Lupitum 125mg Injection 1gm is a parenteral formulation, the chance of overdose may be less. In case of overdose, patients must be closely monitored for signs or symptoms of adverse reactions and appropriate symptomatic treatment instituted. Signs and symptoms of an overdose of Lupitum 125mg Injection 1gm may include neurological effects, including seizures.
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Alcohol

Caution

Avoid/limit the consumption of alcohol.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before receiving Lupitum 125mg Injection 1gm. Lupitum 125mg Injection 1gm should be used during pregnancy only if clearly needed.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Lupitum 125mg Injection 1gm. Lupitum 125mg Injection 1gm should be used with caution in breastfeeding women.

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Driving

Consult your doctor

It is not known if Lupitum 125mg Injection 1gm affects your ability to drive. Drive or operate machinery only if you are alert.

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Liver

Consult your doctor

If you have a history of liver disease, inform your doctor before receiving Lupitum 125mg Injection 1gm.

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Kidney

Consult your doctor

If you have a history of kidney disease, inform your doctor before receiving Lupitum 125mg Injection 1gm.

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Children

Caution

The safety and effectiveness of Lupitum 125mg Injection 1gm in children below 12 years has not been established.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India.
Other Info - LUP0128

Author Details

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Lupitum 125mg Injection 1gm Substitute

Substitutes safety advice
  • KEPHAZON TZ 1125MG INJECTION

    711.00per tablet
  • Cegava TZ Injection 1's

    777.60per tablet
  • Zarobac-T 1.125gm Injection 1's

    477.00per tablet
  • Cefotum-TZ Injection 1's

    432.00per tablet
  • Cefola-XL 1.125 gm Injection 1's

    337.50per tablet

FAQs

Lupitum 125mg Injection 1gm is used to treat Bacterial infections.
Lupitum 125mg Injection 1gm works by inhibiting nucleopeptide synthesis in the bacterial cell wall. It also helps decrease bacterial resistance.
Pseudomembranous colitis, a severe inflammation of the inner lining of the large intestine, has been reported using cephalosporin antibiotics. Therefore, it is necessary to consider its diagnosis in patients who develop diarrhoea associated with antibiotic use.
Dyspepsia (indigestion) might be a side effect of Lupitum 125mg Injection 1gm. To prevent indigestion, eat smaller, more frequent meals and chew your food slowly and thoroughly. However, if the condition persists or worsens, consult the doctor.
Lupitum 125mg Injection 1gm may cause common side effects such as pain and inflammation at the site of injection, nausea, vomiting, and indigestion. These side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.
You should take Lupitum 125mg Injection 1gm for as long as your doctor prescribes it, depending on the type and severity of your infection. It is typically taken for 4 to 14 days. If your symptoms do not improve or get worse, please contact your doctor immediately.
The use of Lupitum 125mg Injection 1gm does not typically cause diarrhoea. However, if you experience diarrhoea unusually or have concerns, please consult your doctor.
Lupitum 125mg Injection 1gm usually starts working within a few hours after taking it. However, the full effect may take a few days, depending on the infection and how your body responds to the medication. Always follow your doctor's instructions and let them know if you do not see any improvement in your symptoms.
If you don't get better after using Lupitum 125mg Injection 1gm, it could be because the infection is resistant to the medication or there might be another underlying cause. Let your doctor know so they can adjust your dose or treatment, check for antibiotic resistance, or look into other possible causes. Always follow your doctor's advice and never stop the medication without consulting them first.
No, you should not stop taking Lupitum 125mg Injection 1gm just because you feel better. It's important to finish the entire course of antibiotics as prescribed by your doctor, even if you start feeling better. Stopping early could cause the infection to return or make the bacteria resistant to the medication.

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