What is the use of Lupitum 125mg Injection 1gm?

Lupitum 125mg Injection 1gm is used to treat Bacterial infections.

Does Lupitum 125mg Injection 1gm cause pseudomembranous colitis?

Pseudomembranous colitis, a severe inflammation of the inner lining of the large intestine, has been reported using cephalosporin antibiotics. Therefore, it is necessary to consider its diagnosis in patients who develop diarrhoea associated with antibiotic use.

Does Lupitum 125mg Injection 1gm cause dyspepsia?

Dyspepsia (indigestion) might be a side effect of Lupitum 125mg Injection 1gm. To prevent indigestion, eat smaller, more frequent meals and chew your food slowly and thoroughly. However, if the condition persists or worsens, consult the doctor.

For how long do I need to take Lupitum 125mg Injection 1gm?

You should take Lupitum 125mg Injection 1gm for as long as your doctor prescribes it, depending on the type and severity of your infection. It is typically taken for 4 to 14 days. If your symptoms do not improve or get worse, please contact your doctor immediately.

Can the use of Lupitum 125mg Injection 1gm cause diarrhoea?

The use of Lupitum 125mg Injection 1gm does not typically cause diarrhoea. However, if you experience diarrhoea unusually or have concerns, please consult your doctor.

How long does Lupitum 125mg Injection 1gm take to work?

Lupitum 125mg Injection 1gm usually starts working within a few hours after taking it. However, the full effect may take a few days, depending on the infection and how your body responds to the medication. Always follow your doctor's instructions and let them know if you do not see any improvement in your symptoms.

What if I don't get better after using Lupitum 125mg Injection 1gm?

If you don't get better after using Lupitum 125mg Injection 1gm, it could be because the infection is resistant to the medication or there might be another underlying cause. Let your doctor know so they can adjust your dose or treatment, check for antibiotic resistance, or look into other possible causes. Always follow your doctor's advice and never stop the medication without consulting them first.

Can I stop taking Lupitum 125mg Injection 1gm when I feel better?

No, you should not stop taking Lupitum 125mg Injection 1gm just because you feel better. It's important to finish the entire course of antibiotics as prescribed by your doctor, even if you start feeling better. Stopping early could cause the infection to return or make the bacteria resistant to the medication.

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Lupitum 125mg Injection 1gm

Lupitum 125mg Injection 1gm, Pack of 1 INJECTION

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Lupitum 125mg Injection 1gm is an antibiotic medicine used to treat bacterial infections such as gynaecological infections, urinary tract infections, post-operative infections, meningitis (inflammation of brain and spinal cord), biliary infections, septicaemia, infections in immune-compromised patients, skin and soft tissue infections, and bone and joint infections. It contains Cefoperazone and Tazobactam. Cefoperazone kills bacteria by inhibiting nucleopeptide synthesis in the bacterial cell wall. Tazobactam reduces bacterial resistance and enhances the activity of Cefoperazone against bacteria. Together, they help to treat bacterial infections.

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Composition :

CEFOPERAZONE-1000MG + TAZOBACTAM-125MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Lupitum 125mg Injection 1gm

Lupitum 125mg Injection 1gm contains Cefoperazone and Tazobactam. Cefoperazone kills bacteria by inhibiting nucleopeptide synthesis in the bacterial cell wall. Tazobactam reduces bacterial resistance and enhances the activity of Cefoperazone against bacteria. Together, Lupitum 125mg Injection 1gm helps to treat bacterial infections.

In some cases, Lupitum 125mg Injection 1gm may cause side effects such as pain and inflammation at the site of injection, nausea, vomiting, and indigestion. These side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.

Consult the doctor if you are pregnant or breastfeeding. The safety and efficacy of Lupitum 125mg Injection 1gm in children below 12 years has not been established. Keep the doctor informed about your health condition and medications to rule out any unpleasant side effects/interactions.

Uses of Lupitum 125mg Injection 1gm

Treatment of Bacterial infections

Directions for Use

Lupitum 125mg Injection 1gm will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Lupitum 125mg Injection 1gm belongs to the group of medicines called antibiotics used to treat bacterial infections such as gynaecological infections, urinary tract infections, post-operative infections, meningitis (inflammation of brain and spinal cord), biliary infections, septicaemia, infections in immune-compromised patients, skin and soft tissue infections, bone and joint infections, and gonorrhoea. Lupitum 125mg Injection 1gm contains Cefoperazone (cephalosporin antibiotic) and Tazobactam (beta-lactamase inhibitor). Cefoperazone kills the bacteria by inhibiting nucleopeptide synthesis in the bacterial cell wall. Tazobactam reduces bacterial resistance and enhances the activity of Cefoperazone against bacteria. Together, Lupitum 125mg Injection 1gm helps to treat bacterial infections.

How Lupitum 125mg Injection 1gm Works

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lupitum 125mg Injection 1gm

Pain and inflammation at the site of injection
Nausea
Vomiting
Indigestion

What if I have taken an overdose of Lupitum 125mg Injection 1gm

As Lupitum 125mg Injection 1gm is a parenteral formulation, the chance of overdose may be less. In case of overdose, patients must be closely monitored for signs or symptoms of adverse reactions and appropriate symptomatic treatment instituted. Signs and symptoms of an overdose of Lupitum 125mg Injection 1gm may include neurological effects, including seizures.

Drug Warnings

Do not receive Lupitum 125mg Injection 1gm if you are allergic to any of its components. Consult the doctor if you are pregnant or breastfeeding. The safety and efficacy of Lupitum 125mg Injection 1gm in children below 12 years has not been established. Let the doctor know if you take prescription/non-prescription medicines, including supplements or herbal products.

Drug-Drug Interactions

CefoperazoneBCG vaccine

Critical

CefoperazoneRifampicin

Severe

Drug-Drug Interactions

CefoperazoneBCG vaccine

Critical

How does the drug interact with Lupitum 125mg Injection 1gm:
When BCG vaccine is used with Lupitum 125mg Injection 1gm, its effectiveness may be reduced.

How to manage the interaction:
Taking Lupitum 125mg Injection 1gm with BCG vaccine is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor

CefoperazoneRifampicin

Severe

How does the drug interact with Lupitum 125mg Injection 1gm:
Taking Lupitum 125mg Injection 1gm and Rifampicin together may increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Lupitum 125mg Injection 1gm and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Diet & Lifestyle Advise

Include whole grains, fruits, and vegetables in your diet.
Taking probiotics after antibiotics and eating high-fibre and prebiotic foods may help reduce side effects and support digestion.
Exercising regularly helps in improving overall health.
Rest well, and get plenty of sleep.
Avoid smoking and alcohol consumption.
Meditation and yoga can help lower stress.
Avoid processed and fried food.

Habit Forming

Therapeutic Class

ANTIBIOTICS

Lupitum 125mg Injection 1gm Substitute

KEPHAZON TZ 1125MG INJECTION
by Others
₹711.00per tablet
Cegava TZ Injection 1's
by Others
₹777.60per tablet
Zonkind-Tazo 1.125gm Injection
by AYUR
₹472.50per tablet
Lypex Tz 1.125Mg Inj
by AYUR
₹481.50per tablet
Cefotum-TZ Injection 1's
by Others
₹432.00per tablet

Product Substitutes

KEPHAZON TZ 1125MG INJECTION

₹711

MRP ₹790

Cegava TZ Injection 1's

₹777.6

MRP ₹864

Zonkind-Tazo 1.125gm Injection

₹472.5

MRP ₹525

Lypex Tz 1.125Mg Inj

₹481.5

MRP ₹535

Cefotum-TZ Injection 1's

₹432

MRP ₹480

Cofaso-TZ 1125 Injection 1's

₹539.1

MRP ₹599

Cefola-XL 1.125 gm Injection 1's

₹337.5

MRP ₹375

Zarobac-T 1.125gm Injection 1's

₹477

MRP ₹530

Zaroran-T Injection 1's

₹565.2

MRP ₹628

C-Zone-TZ Injection 1.125 gm

₹925

Cefotis TZ 1125 mg Injection 1's

₹398

Alcohol

Caution

Avoid/limit the consumption of alcohol.

Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before receiving Lupitum 125mg Injection 1gm. Lupitum 125mg Injection 1gm should be used during pregnancy only if clearly needed.

Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Lupitum 125mg Injection 1gm. Lupitum 125mg Injection 1gm should be used with caution in breastfeeding women.

Driving

Consult your doctor

It is not known if Lupitum 125mg Injection 1gm affects your ability to drive. Drive or operate machinery only if you are alert.

Liver

Consult your doctor

If you have a history of liver disease, inform your doctor before receiving Lupitum 125mg Injection 1gm.

Kidney

Consult your doctor

If you have a history of kidney disease, inform your doctor before receiving Lupitum 125mg Injection 1gm.

Children

Caution

The safety and effectiveness of Lupitum 125mg Injection 1gm in children below 12 years has not been established.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India.

Other Info - LUP0128

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Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 9:31 AM IST

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Composition :

Manufacturer/Marketer :

Consume Type :

Return Policy :

Expires on or after :

Drug-Drug Interactions

Drug-Food Interactions

Lupitum 125mg Injection 1gm Substitute

KEPHAZON TZ 1125MG INJECTION

Cegava TZ Injection 1's

Zonkind-Tazo 1.125gm Injection

Lypex Tz 1.125Mg Inj

Cefotum-TZ Injection 1's

KEPHAZON TZ 1125MG INJECTION

Cegava TZ Injection 1's

Zonkind-Tazo 1.125gm Injection

Lypex Tz 1.125Mg Inj

Cefotum-TZ Injection 1's

Cofaso-TZ 1125 Injection 1's

Cefola-XL 1.125 gm Injection 1's

Zarobac-T 1.125gm Injection 1's

Zaroran-T Injection 1's

C-Zone-TZ Injection 1.125 gm

Cefotis TZ 1125 mg Injection 1's

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Disclaimer

Author Details

Reference