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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Lox 2% Injection is used as an local anaesthesia during surgery or medical procedures. This medicine is also used in the management of ventricular arrhythmia (abnormal heartbeat). It prevents the beginning and conduction of impulses by obstructing the influx (entry) of sodium ions into the membrane surrounding the nerves.
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Composition :

LIDOCAINE-2%

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Lox 2% Injection

Lox 2% Injection is indicated for the production of regional or local anaesthesia during surgery or medical procedures. Additionally, it is indicated in the management of ventricular arrhythmia (abnormal heartbeat) associated with acute myocardial infarction, or cardiac surgery. 

Lox 2% Injection contains ‘Lidocaine’ that blocks the influx (entry) of sodium ions into the membrane that surrounds the nerves, thereby preventing initiation and conduction of impulses; hence providing an anaesthetic effect. Lox 2% Injection blocks cardiac sodium channels, thereby treating arrhythmia.

Lox 2% Injection will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side-effects such as dizziness, high/low blood pressure, nausea, vomiting, and paresthesia (burning or prickling sensation). You are advised to talk to your doctor if you experience these side effects persistently.

Do not take Lox 2% Injection if you are allergic to any of its components. Consult your doctor if you are pregnant, planning for pregnancy or breastfeeding. Avoid driving or operating machinery as Lox 2% Injection may cause dizziness, drowsiness, and loss of sensation. Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Uses of Lox 2% Injection

Used for Local anesthesia and treatment of ventricular arrhythmia

Directions for Use

Lox 2% Injection will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

Lox 2% Injection is indicated for the production of regional or local anaesthesia in case of surgeries or medical procedures. Also, it is indicated in the management of ventricular arrhythmias (abnormal heartbeat) associated with acute myocardial infarction, or cardiac surgery. Lox 2% Injection blocks the influx (entry) of sodium ions into the membrane that surrounds the nerves, thereby preventing initiation and conduction of impulses and hence providing an anaesthetic effect. It blocks cardiac sodium channels, thereby treating arrhythmia.

How Lox 2% Injection Works

Lox 2% Injection contains ‘Lidocaine’ that blocks the influx (entry) of sodium ions into the membrane that surrounds the nerves, thereby preventing initiation and conduction of impulses; hence providing an anaesthetic effect. Lox 2% Injection blocks cardiac sodium channels, thereby treating arrhythmia.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lox 2% Injection

  • Nausea
  • Vomiting
  • High/low blood pressure
  • Dizziness
  • Paresthesia (burning or prickling sensation)

What if I have taken an overdose of Lox 2% Injection

Lox 2% Injection is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Symptoms of overdose may include CNS depression, including unconsciousness and coma. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

Do not take Lox 2% Injection if you are allergic to any of its components. Inform your doctor if you have hypovolemia (low blood volume), blood clotting problems, bleeding problems, slow heart rate, myasthenia gravis (muscle problems), epilepsy, heart, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Avoid driving or operating machinery as Lox 2% Injection may cause dizziness, drowsiness and loss of sensation. Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Drug-Drug Interactions

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LidocaineArbutamine
Critical
LidocaineSaquinavir
Critical

Drug-Drug Interactions

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LidocaineArbutamine
Critical
How does the drug interact with Lox 2% Injection 30 ml:
Taking Lox 2% Injection 30 ml and Arbutamine together can affect the rhythm of your heart.

How to manage the interaction:
Taking Lox 2% Injection 30 ml with arbutamine is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience irregular heartbeat, chest tightness, blurred vision and nausea. Do not discontinue any medication without consulting a doctor.
LidocaineSaquinavir
Critical
How does the drug interact with Lox 2% Injection 30 ml:
Taking Lox 2% Injection 30 ml with Saquinavir can increase the blood levels of Lox 2% Injection 30 ml and cause an irregular heart rhythm.

How to manage the interaction:
Taking Lox 2% Injection 30 ml with Saquinavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting and rapid heartbeat. Do not discontinue any medications without consulting a doctor.
LidocaineIfosfamide
Severe
How does the drug interact with Lox 2% Injection 30 ml:
Coadministration of Ifosfamide with Lox 2% Injection 30 ml can increase the risk of methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
There may be a possibility of interaction between Ifosfamide and Lox 2% Injection 30 ml, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
LidocaineAtazanavir
Severe
How does the drug interact with Lox 2% Injection 30 ml:
Taking Lox 2% Injection 30 ml with Atazanavir can increase the effects of Lox 2% Injection 30 ml.

How to manage the interaction:
There may be a possibility of interaction between Lox 2% Injection 30 ml and Atazanavir, but it can be taken if prescribed by a doctor. If you notice any of these symptoms - irregular heartbeat, chest tightness, blurred vision or nausea. - it's important to contact a doctor. Do not stop using any medications without talking to a doctor.
LidocaineFosamprenavir
Severe
How does the drug interact with Lox 2% Injection 30 ml:
Taking Lox 2% Injection 30 ml and Fosamprenavir may increase the blood levels of Lox 2% Injection 30 ml, which increases the risk of serious side effects.

How to manage the interaction:
Although taking Lox 2% Injection 30 ml and Fosamprenavir together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LidocaineBupropion
Severe
How does the drug interact with Lox 2% Injection 30 ml:
Taking Lox 2% Injection 30 ml with bupropion can increase the risk of seizures(fits).

How to manage the interaction:
Co-administration of bupropion along with Lox 2% Injection 30 ml can lead to an interaction, it can be taken if recommended by a doctor. In case you experience any unusual side effects, consult a doctor. Do not discontinue any medications without consulting a doctor.
LidocaineMetrizamide
Severe
How does the drug interact with Lox 2% Injection 30 ml:
Taking Lox 2% Injection 30 ml and Metrizamide may increase the risk of causing seizures(fits).

How to manage the interaction:
Although taking Lox 2% Injection 30 ml and Metrizamide together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
LidocainePhenazopyridine
Severe
How does the drug interact with Lox 2% Injection 30 ml:
Taking phenazopyridine with Lox 2% Injection 30 ml can increase the risk of methemoglobinemia(a blood disorder in which too little oxygen is delivered to the cells).

How to manage the interaction:
Co-administration of Phenazopyridine with Lox 2% Injection 30 ml can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
LidocaineNitrofurantoin
Severe
How does the drug interact with Lox 2% Injection 30 ml:
Taking Lox 2% Injection 30 ml with Nitrofurantoin may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Taking Nitrofurantoin with Lox 2% Injection 30 ml together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LidocaineIsosorbide dinitrate
Severe
How does the drug interact with Lox 2% Injection 30 ml:
Taking isosorbide dinitrate with Lox 2% Injection 30 ml may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking isosorbide dinitrate and Lox 2% Injection 30 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include a diet rich in whole grains, lean proteins, vegetables, and fruits.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with a proper diet and safe exercises.
  • Manage stress with meditation and yoga.

Habit Forming

No

Therapeutic Class

VASOPRESSORS

Lox 2% Injection Substitute

Substitutes safety advice
  • Xylocaine 2% IM Injection 30 ml

    by Others

    1.04per tablet
  • Lox 2% Injection 2 ml

    by Others

    15.97per tablet
  • Afdcain 2% Inj 30Ml

    by Others

    1.06per tablet
  • Lignocaine with Adrenaline 2% Injection 1's

    by Others

    14.85per tablet
  • Resocaine 2% Gel

    by Others

    0.87per tablet
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Alcohol

Caution

It is not known if alcohol affects Lox 2% Injection. Please consult your doctor if you have any concerns regarding this.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor if you are breastfeeding. Your doctor will decide if Lox 2% Injection can be taken by breastfeeding mothers or not.

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Driving

Caution

Avoid driving or operating machinery as Lox 2% Injection may cause dizziness, drowsiness and loss of sensation.

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Liver

Caution

Lox 2% Injection should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have any concerns regarding this.

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Kidney

Caution

Lox 2% Injection should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have any concerns regarding this.

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Children

Caution

Limited information is available. Please consult your doctor if you have any concerns regarding the usage of Lox 2% Injection in children.

FAQs

Lox 2% Injection is indicated for the production of regional or local anaesthesia during surgery or medical procedures. Additionally, it is indicated in the management of ventricular arrhythmia (abnormal heartbeat) associated with acute myocardial infarction, or cardiac surgery.
Lox 2% Injection blocks the influx (entry) of sodium ions into the membrane that surrounds the nerves, thereby preventing initiation and conduction of impulses and hence providing an anaesthetic effect. Lox 2% Injection blocks cardiac sodium channels, thereby treats arrhythmia.
Lox 2% Injection may cause hypotension (low blood pressure) or hypertension (high blood pressure). Therefore, regular monitoring of blood pressure is advised whilst on treatment with Lox 2% Injection.
Nausea and vomiting might be a side effect of Lox 2% Injection. It is not necessary for everyone taking Lox 2% Injection to experience these side effects. However, if the condition persists or worsens, please consult a doctor.
Lox 2% Injection might increase creatinine phosphokinase levels. Therefore, if you are undergoing any tests, inform the person doing the tests that you have taken Lox 2% Injection.

Country of origin

INDIA

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - LOX0002

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