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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Nov 23, 2024 | 4:50 PM IST
Losterol 300mg Tablet is used to treat raised or increased levels of cholesterol or fat/oils. It contains Gemfibrozil, which increases the natural substance that breaks down fats in the bloodstream, thereby increasing its utilization and removal. As a result, it decreases harmful cholesterol like LDL (bad cholesterol) and triglycerides (TG) and increases levels of HDL (good cholesterol). It may cause side effects such as vomiting, abdominal pain, nausea, flatulence, and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Gnosis Pharmaceuticals Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Losterol 300mg Tablet

Losterol 300mg Tablet belongs to a group of medications called 'fibric acid derivatives' or 'fibrates' primarily used to treat raised or increased levels of cholesterol or fat/oils. Hyperlipidaemia or hypertriglyceridemia is a condition in which there is a high level of low-density lipoproteins (LDL) or bad cholesterol and a decreased level of high-density lipoprotein (HDL) or good cholesterol. Increased bad cholesterol level leads to a high risk of heart attack and stroke in the future, especially for heart disease patients.

Losterol 300mg Tablet contains 'Gemfibrozil', which works by increasing the natural substance that breaks down fats in the bloodstream, thereby increasing its utilization and removal. As a result, Losterol 300mg Tablet decreases harmful cholesterol like LDL (bad cholesterol) and triglycerides (TG) and increases levels of HDL (good cholesterol).

Take Losterol 300mg Tablet as prescribed by your doctor. You are advised to take Losterol 300mg Tablet for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience vomiting, abdominal pain, nausea, flatulence, and diarrhoea. Most of these side effects of Losterol 300mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

It is important to have your cholesterol and triglyceride levels (lipid profile) checked regularly. Before starting Losterol 300mg Tablet, please inform your doctor if you have any allergies, severe kidney disease, severe liver disease, or gallbladder disease. Inform your doctor if you have ever had gallstones, cataracts (clouding in the eye lens that causes decreased vision) and heart disease. Inform your doctor if you have taken other cholesterol medicines with this Losterol 300mg Tablet. Immediately contact your doctor if you are pregnant and breastfeeding.

Uses of Losterol 300mg Tablet

Treatment of High cholesterol levels.

Medicinal Benefits

Losterol 300mg Tablet belongs to a group of medications called 'fibric acid derivatives' or 'fibrates' primarily used to treat raised or increased levels of cholesterol or fat/oils. Losterol 300mg Tablet works by increasing the natural substance that breaks down fats in the bloodstream, thereby increasing its utilization and removal. As a result, Losterol 300mg Tablet decreases harmful cholesterol like LDL (bad cholesterol) and triglycerides (TG) and increases levels of HDL (good cholesterol).

Directions for Use

Take Losterol 300mg Tablet as prescribed by your doctor. Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Losterol 300mg Tablet

  • Vomiting
  • Increased liver enzymes
  • Abdominal pain
  • Nausea
  • Flatulence
  • Diarrhoea.

Drug Warnings

Before taking Losterol 300mg Tablet, tell your doctor if you are allergic to any fibrate products. Inform your doctor if you ever had rhabdomyolysis (high risk of muscle breakdown), thyroid disease, history of muscle pain and weakness. If you are above 70 years, then contact your doctor before taking this Losterol 300mg Tablet. Before starting Losterol 300mg Tablet, please inform your doctor if you have any allergy, severe kidney disease, severe liver disease, and gallbladder disease before starting $ name. Inform your doctor if you have ever had gallstones, cataracts (clouding in the eye's lens that causes decreased vision), diabetes, and heart disease. Inform your doctor if you have taken other cholesterol medicines with this Losterol 300mg Tablet. Immediately contact your doctor if you are pregnant and breastfeeding. The use of alcohol with Losterol 300mg Tablet increases liver damage, so its use should be avoided.

Drug Interactions

Drug-Drug Interaction: Losterol 300mg Tablet interacts with blood sugar lowering pills (rosiglitazone, pioglitazone, repaglinide), a drug used to treat hepatitis C infection (dasabuvir), other medicines used to lower cholesterol levels (atorvastatin, lovastatin, pravastatin, rosuvastatin), medicines for cancer (dabrafenib), medicines for diarrhoea (loperamide), medicines for asthma (montelukast), blood thinner (warfarin, acenocoumarol, and phenprocoumon), antigout (colchicine).

Drug-Food Interaction: Avoid food containing excess fat. Avoid grapefruit juice while taking Losterol 300mg Tablet.

Drug-Disease Interaction: Losterol 300mg Tablet should not be given in the condition of liver diseases like biliary cirrhosis (fatty liver disease), Rhabdomyolysis (the breakdown of muscles) and gall stones (cholelithiasis).

Drug-Drug Interactions Checker List

  • ROSIGLITAZONE
  • PIOGLITAZONE
  • REPAGLINIDE
  • ATORVASTATIN
  • PRAVASTATIN
  • ROSUVASTATIN
  • LOPERAMIDE
  • MONTELUKAST
  • WARFARIN
  • ACENOCOUMAROL
  • PHENPROCOUMON
  • COLCHICINE
  • DASABVIR
  • LOVASTATIN
  • DABRAFENIB

Habit Forming

No

Diet & Lifestyle Advise

  • Losterol 300mg Tablet is generally given in addition to regular exercise and a low-fat diet to lower fat levels in the blood.

  • A low cholesterol diet and a regular exercise regime are found to complement treatment with Losterol 300mg Tablet effectively.

  • As a precautionary measure, you are recommended not to consume alcohol, junk food items from outside, stick to freshly prepared home-cooked meals and take proper rest, for a speedy recovery.

  • Try to replace most of your saturated fats with unsaturated fats can reduce total cholesterol and LDL cholesterol in a short span of time.

  • Foods like avocados, olive oil, fatty fish, and nuts contain many heart-healthy unsaturated fats, so it is beneficial to eat them regularly.

  • Regular exercise can make your heart strong and decrease your risk of a heart attack.

Special Advise

  • You should have your lipid profile test including total cholesterol (TC), triglycerides (TG), LDL, HDL, VLDL every 6 months to ensure whether Losterol 300mg Tablet is working or not.
  • Your doctor may check your liver function before starting treatment and regularly thereafter. 
  • Gemfibrozil may cause you to develop gallstones. If you develop gallstones, you should consult your doctor.

Disease/Condition Glossary

Hyperlipidemia occurs when there are too many lipids (or fats), like cholesterol and triglycerides (TG). Hypercholesterolemia is a type of Hyperlipidemia in which there is excessive low-density lipoprotein - LDL (bad cholesterol) and low level of high-density lipoprotein - HDL (good cholesterol) in your blood. This condition increases the deposition of fats on the lining of heart arteries, increasing the risk of heart blockage and other blood clot problems. 

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Alcohol

Unsafe

Alcohol may interact with Losterol 300mg Tablet. Therefore, avoid the use of alcohol while taking this Losterol 300mg Tablet.

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Pregnancy

Unsafe

It is not known whether Losterol 300mg Tablet will harm an unborn baby. Inform your doctor if you are pregnant or plan to become pregnant while using this Losterol 300mg Tablet.

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Breast Feeding

Unsafe

It is unknown whether Losterol 300mg Tablet passes into breast milk or if it could harm a nursing baby. It would be best if you did not breast-feed while taking Losterol 300mg Tablet.

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Driving

Caution

Although unlikely, you may feel dizzy or experience visual disturbances whilst taking this Losterol 300mg Tablet.

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Liver

Caution

Losterol 300mg Tablet to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Losterol 300mg Tablet to be taken with caution, especially if you have a history of kidney disease or is currently on the dialysis stage. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Losterol 300mg Tablet is not recommended for children.

Country of origin

India
Other Info - LO12520

Author Details

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FAQs

Losterol 300mg Tablet is used to treat raised or increased levels of cholesterol or fat/oils.
Yes, you may use Losterol 300mg Tablet with niacin if recommended by your doctor because Losterol 300mg Tablet along with niacin can be used in patients with very high fat.
Follow the diet suggested by your doctor. Losterol 300mg Tablet will not help lower your cholesterol if you do not follow a cholesterol-lowering diet plan. Avoid drinking alcohol. It may disturb your treatment.
Usually, it is not safe to take Losterol 300mg Tablet with fusidic acid as it may lead to muscle weakness, tenderness or pain. Please consult your doctor before taking Losterol 300mg Tablet along with fusidic acid.
You should not take Losterol 300mg Tablet if you have gallbladder disease, severe liver or kidney disease. If you are also taking repaglinide or simvastatin, then you should not take Losterol 300mg Tablet.
Losterol 300mg Tablet is used with caution in patients taking warfarin, adjustments in warfarin may be required, consult your doctor before taking Losterol 300mg Tablet along with warfarin.
Losterol 300mg Tablet is a fibrate. It belongs to the group of medications called fibric acid derivatives. It is used in the treatment of high cholesterol levels.
Yes, Losterol 300mg Tablet is generally considered safe when used as directed by your doctor. However, like all medications, it can cause side effects and interact with other drugs. Common side effects are usually mild and temporary, but rare cases of more serious side effects can occur. To ensure safe use, it's essential to follow your doctor's instructions and dosage, inform your doctor about all medications, supplements, and medical conditions, and monitor your liver function and blood counts regularly. By being mindful of these factors and reporting any side effects or concerns to your doctor, you can minimize risks and enjoy the benefits of Losterol 300mg Tablet.
Losterol 300mg Tablet and fenofibrate are two different medications for treating high cholesterol and triglycerides. They belong to the same class of drugs but have distinct differences. Fenofibrate is often used first to treat high triglycerides, while gemfibrozil is reserved for patients who can't take other medications. They are not interchangeable; your doctor will determine which is best for you.
Using Losterol 300mg Tablet together with simvastatin is not recommended. Combining these medications can increase the risk of side effects such as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue.
Losterol 300mg Tablet is not usually linked to weight changes, hair loss, constipation, or erectile dysfunction. However, it can cause diarrhoea in some people. If you notice any unusual symptoms, you must talk with your doctor to determine the cause and make any necessary adjustments to your treatment.

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