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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Lopid Capsule is used to treat raised or increased levels of cholesterol or fat/oils. It contains Gemfibrozil, which increases the natural substance that breaks down fats in the bloodstream, thereby increasing its utilization and removal. As a result, it decreases harmful cholesterol like LDL (bad cholesterol) and triglycerides (TG) and increases levels of HDL (good cholesterol). It may cause side effects such as vomiting, abdominal pain, nausea, flatulence, and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

GEMFIBROZIL-300MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Lopid Capsule

Lopid Capsule belongs to a group of medications called 'fibric acid derivatives' or 'fibrates' primarily used to treat raised or increased levels of cholesterol or fat/oils. Hyperlipidaemia or hypertriglyceridemia is a condition in which there is a high level of low-density lipoproteins (LDL) or bad cholesterol and a decreased level of high-density lipoprotein (HDL) or good cholesterol. Increased bad cholesterol level leads to a high risk of heart attack and stroke in the future, especially for heart disease patients.

Lopid Capsule contains 'Gemfibrozil', which works by increasing the natural substance that breaks down fats in the bloodstream, thereby increasing its utilization and removal. As a result, Lopid Capsule decreases harmful cholesterol like LDL (bad cholesterol) and triglycerides (TG) and increases levels of HDL (good cholesterol).

Take Lopid Capsule as prescribed by your doctor. You are advised to take Lopid Capsule for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience vomiting, abdominal pain, nausea, flatulence, and diarrhoea. Most of these side effects of Lopid Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

It is important to have your cholesterol and triglyceride levels (lipid profile) checked regularly. Before starting Lopid Capsule , please inform your doctor if you have any allergies, severe kidney disease, severe liver disease, or gallbladder disease. Inform your doctor if you have ever had gallstones, cataracts (clouding in the eye lens that causes decreased vision) and heart disease. Inform your doctor if you have taken other cholesterol medicines with this Lopid Capsule . Immediately contact your doctor if you are pregnant and breastfeeding.

Uses of Lopid Capsule

Treatment of High cholesterol levels.

Directions for Use

Take Lopid Capsule as prescribed by your doctor. Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Lopid Capsule belongs to a group of medications called 'fibric acid derivatives' or 'fibrates' primarily used to treat raised or increased levels of cholesterol or fat/oils. Lopid Capsule works by increasing the natural substance that breaks down fats in the bloodstream, thereby increasing its utilization and removal. As a result, Lopid Capsule decreases harmful cholesterol like LDL (bad cholesterol) and triglycerides (TG) and increases levels of HDL (good cholesterol).

How Lopid Capsule Works

Lopid Capsule contains 'Gemfibrozil', which works by increasing the natural substance that breaks down fats in the bloodstream, thereby increasing its utilization and removal. As a result, Lopid Capsule decreases harmful cholesterol like LDL (bad cholesterol) and triglycerides (TG) and increases levels of HDL (good cholesterol).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lopid Capsule

  • Vomiting
  • Increased liver enzymes
  • Abdominal pain
  • Nausea
  • Flatulence
  • Diarrhoea.

What if I have taken an overdose of Lopid Capsule

Do not take more than the prescribed dose of Lopid Capsule as it may cause overdose. The symptoms of overdose include stomach cramps, diarrhoea, increased enzymes in the body (signs of this are muscle pain, tenderness, weakness, swelling, urine becomes dark in colour), feeling or being sick, joint or muscle pain. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Before taking Lopid Capsule , tell your doctor if you are allergic to any fibrate products. Inform your doctor if you ever had rhabdomyolysis (high risk of muscle breakdown), thyroid disease, history of muscle pain and weakness. If you are above 70 years, then contact your doctor before taking this Lopid Capsule . Before starting Lopid Capsule , please inform your doctor if you have any allergy, severe kidney disease, severe liver disease, and gallbladder disease before starting $ name. Inform your doctor if you have ever had gallstones, cataracts (clouding in the eye's lens that causes decreased vision), diabetes, and heart disease. Inform your doctor if you have taken other cholesterol medicines with this Lopid Capsule . Immediately contact your doctor if you are pregnant and breastfeeding. The use of alcohol with Lopid Capsule increases liver damage, so its use should be avoided.

Drug-Drug Interactions

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GemfibrozilRepaglinide
Critical
GemfibrozilSelexipag
Critical

Drug-Drug Interactions

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GemfibrozilRepaglinide
Critical
How does the drug interact with Lopid Capsule 10's:
When Repaglinide is taken with Lopid Capsule 10's, the level of Repaglinide in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Repaglinide with Lopid Capsule 10's can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GemfibrozilSelexipag
Critical
How does the drug interact with Lopid Capsule 10's:
When Selexipag is taken with Lopid Capsule 10's, the amount of Selexipag in the blood can go up. This can increase the risk or severity of side effects like anemia, muscle and joint pain, or electrolyte imbalance.

How to manage the interaction:
Taking Selexipag with Lopid Capsule 10's can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle and joint pain, diarrhea, sudden dizziness, lightheadedness, fainting, shortness of breath, nausea, vomiting, flushing, and decreased appetite, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GemfibrozilAtorvastatin
Severe
How does the drug interact with Lopid Capsule 10's:
When Lopid Capsule 10's is taken with Atorvastatin, the chance of side effects such as liver damage and rhabdomyolysis, (an uncommon illness involving the breakdown of skeletal muscle tissue) increases.

How to manage the interaction:
Co-administration of Atorvastatin along with Lopid Capsule 10's together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
GemfibrozilFluvastatin
Severe
How does the drug interact with Lopid Capsule 10's:
Co-administration of Lopid Capsule 10's with Fluvastatin can develop or increase the risk of side effects like muscle damage or liver injury.

How to manage the interaction:
There may be a possibility of interaction between Fluvastatin and Lopid Capsule 10's, but it can be taken if prescribed by a doctor. If you notice any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
GemfibrozilRosuvastatin
Severe
How does the drug interact with Lopid Capsule 10's:
Co-administration of Lopid Capsule 10's and Rosuvastatin may increase the risk or severity of side effects like muscle injury.

How to manage the interaction:
Co-administration of Lopid Capsule 10's and Rosuvastatin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, or dark-colored urine, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
GemfibrozilPioglitazone
Severe
How does the drug interact with Lopid Capsule 10's:
When Pioglitazone is taken with Lopid Capsule 10's, the level of Pioglitazone in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Pioglitazone with Lopid Capsule 10's together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience visual abnormalities, excessive or quick weight gain, swelling in the ankles or legs, trouble breathing, unusual fatigue, chest discomfort or tightness, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, light coloured stools, or yellowing of the skin or eyes, seek medical attention immediately. Do not discontinue any medications without consulting a doctor.
GemfibrozilLoperamide
Severe
How does the drug interact with Lopid Capsule 10's:
When taken in combination Lopid Capsule 10's may significantly raise the Loperamide levels in the blood. This can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Although taking Loperamide with Lopid Capsule 10's together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
GemfibrozilPravastatin
Severe
How does the drug interact with Lopid Capsule 10's:
Taking Lopid Capsule 10's with Pravastatin can increase the risk or severity of muscle damage or liver damage.

How to manage the interaction:
Although taking Pravastatin and Lopid Capsule 10's together can evidently cause an interaction, it can be taken if a doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GemfibrozilBexarotene
Severe
How does the drug interact with Lopid Capsule 10's:
When Bexarotene is taken with Lopid Capsule 10's, it can cause a decrease in the metabolism of Bexarotene. This can reduce the levels and treatment outcomes of Bexarotene.

How to manage the interaction:
Although there is a possible interaction between Lopid Capsule 10's and Bexarotene, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.
GemfibrozilWarfarin
Severe
How does the drug interact with Lopid Capsule 10's:
Co-administration of Warfarin with Lopid Capsule 10's can increase the risk of bleeding.

How to manage the interaction:
Although taking Lopid Capsule 10's and Warfarin together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience unusual bleeding, bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Lopid Capsule is generally given in addition to regular exercise and a low-fat diet to lower fat levels in the blood.

  • A low cholesterol diet and a regular exercise regime are found to complement treatment with Lopid Capsule effectively.

  • As a precautionary measure, you are recommended not to consume alcohol, junk food items from outside, stick to freshly prepared home-cooked meals and take proper rest, for a speedy recovery.

  • Try to replace most of your saturated fats with unsaturated fats can reduce total cholesterol and LDL cholesterol in a short span of time.

  • Foods like avocados, olive oil, fatty fish, and nuts contain many heart-healthy unsaturated fats, so it is beneficial to eat them regularly.

  • Regular exercise can make your heart strong and decrease your risk of a heart attack.

Habit Forming

No

Therapeutic Class

CARDIOVASCULAR AGENTS

Lopid Capsule Substitute

Substitutes safety advice
  • Fibrolip 300 Tablet 10's

    22.68per tablet
  • Oxipace 300mg Tablet

    14.31per tablet
  • Losterol 300mg Tablet

    4.86per tablet
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Alcohol

Unsafe

Alcohol may interact with Lopid Capsule . Therefore, avoid the use of alcohol while taking this Lopid Capsule .

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Pregnancy

Unsafe

It is not known whether Lopid Capsule will harm an unborn baby. Inform your doctor if you are pregnant or plan to become pregnant while using this Lopid Capsule .

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Breast Feeding

Unsafe

It is unknown whether Lopid Capsule passes into breast milk or if it could harm a nursing baby. It would be best if you did not breast-feed while taking Lopid Capsule .

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Driving

Caution

Although unlikely, you may feel dizzy or experience visual disturbances whilst taking this Lopid Capsule .

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Liver

Caution

Lopid Capsule to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Lopid Capsule to be taken with caution, especially if you have a history of kidney disease or is currently on the dialysis stage. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Lopid Capsule is not recommended for children.

FAQs

Lopid Capsule is used to treat raised or increased levels of cholesterol or fat/oils.
Yes, you may use Lopid Capsule with niacin if recommended by your doctor because Lopid Capsule along with niacin can be used in patients with very high fat.
Follow the diet suggested by your doctor. Lopid Capsule will not help lower your cholesterol if you do not follow a cholesterol-lowering diet plan. Avoid drinking alcohol. It may disturb your treatment.
Usually, it is not safe to take Lopid Capsule with fusidic acid as it may lead to muscle weakness, tenderness or pain. Please consult your doctor before taking Lopid Capsule along with fusidic acid.
You should not take Lopid Capsule if you have gallbladder disease, severe liver or kidney disease. If you are also taking repaglinide or simvastatin, then you should not take Lopid Capsule .
Lopid Capsule is used with caution in patients taking warfarin, adjustments in warfarin may be required, consult your doctor before taking Lopid Capsule along with warfarin.
Lopid Capsule is a fibrate. It belongs to the group of medications called fibric acid derivatives. It is used in the treatment of high cholesterol levels.
Yes, Lopid Capsule is generally considered safe when used as directed by your doctor. However, like all medications, it can cause side effects and interact with other drugs. Common side effects are usually mild and temporary, but rare cases of more serious side effects can occur. To ensure safe use, it's essential to follow your doctor's instructions and dosage, inform your doctor about all medications, supplements, and medical conditions, and monitor your liver function and blood counts regularly. By being mindful of these factors and reporting any side effects or concerns to your doctor, you can minimize risks and enjoy the benefits of Lopid Capsule .
Lopid Capsule and fenofibrate are two different medications for treating high cholesterol and triglycerides. They belong to the same class of drugs but have distinct differences. Fenofibrate is often used first to treat high triglycerides, while gemfibrozil is reserved for patients who can't take other medications. They are not interchangeable; your doctor will determine which is best for you.
Using Lopid Capsule together with simvastatin is not recommended. Combining these medications can increase the risk of side effects such as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue.
Lopid Capsule is not usually linked to weight changes, hair loss, constipation, or erectile dysfunction. However, it can cause diarrhoea in some people. If you notice any unusual symptoms, you must talk with your doctor to determine the cause and make any necessary adjustments to your treatment.

Country of origin

India

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051
Other Info - LOP0007

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