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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Lomoother 40 Capsule is used to treat Brain Tumors and Hodgkin's Disease. It contains Lomustine, which belongs to the alkylating agent’s class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This causes shrinkage of tumor cells and thereby prevents the growth and further spread of cancerous or non-cancerous cells. Common side effects of this medication may include nausea, vomiting, headache, visual disturbances, blindness, disorientation, lack of energy, loss of control, and difficulty talking.

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Composition :

LOMUSTINE-40MG

Manufacturer/Marketer :

Therdose Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Lomoother 40 Capsule

Lomoother 40 Capsule is an anti-cancer medicine used in the treatment of brain tumors. A tumor is defined as the formation of solid mass tissue due to the abnormal growth of cells. Lomoother 40 Capsule is used in the treatment of primary and metastatic brain tumors along with appropriate surgical or radiotherapeutic procedures. A brain tumor is a serious condition where the cells (cancerous or non-cancerous) grow abnormally in the brain. Lomoother 40 Capsule is also used in the treatment of Hodgkin’s Disease when used in combination with other chemotherapies.

Lomoother 40 Capsule contains Lomustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This causes shrinkage of tumor cells and thereby prevents the growth and further spread of cancerous or non-cancerous cells.

Lomoother 40 Capsule may cause certain side effects, such as nausea, vomiting, headache, visual disturbances, blindness, disorientation, lack of energy, loss of control, and difficulty talking. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Lomoother 40 Capsule should be taken as prescribed by your doctor. Do not take more than the recommended dose of medicine.

Lomoother 40 Capsule should be avoided if you are allergic to it or any other components present in it. Lomoother 40 Capsule may cause pulmonary toxicity, delayed myelosuppression, pulmonary fibrosis, nephrotoxicity, and hepatotoxicity in some patients. Hence, careful monitoring should be done during the entire treatment. This medicine is known to cause embryo-fetal harm in pregnant women. Hence, inform your doctor if you are pregnant or are planning to become pregnant. It is unknown whether Lomoother 40 Capsule is suitable for children's use. Hence, please consult your doctor or paediatrician for information on children's use. Breastfeeding should be discontinued in nursing mothers during the treatment. Lomoother 40 Capsule should only be taken once in 6 weeks as taking more than the recommended dose can cause serious life-threatening problems. Hence, talk to your doctor or pharmacist before starting the treatment.

Uses of Lomoother 40 Capsule

Lomoother 40 Capsule is used in the treatment of Brain Tumors and Hodgkin's Disease

Directions for Use

Take Lomoother 40 Capsule as prescribed by your doctor. Do not take more than the prescribed dose of medicine, as it can cause fatal toxicity. Swallow the medicine as a whole with a glass of water. Do not chew, crush, or break the medicine. This medicine should be taken on an empty stomach 30 minutes before food or at least 2 hours after food. For children who cannot swallow the medicine as a whole, open the capsule and add the powder to a very small amount (1 teaspoon) of applesauce/ice cream and make your child eat all the mixture.

Medicinal Benefits

Lomoother 40 Capsule contains Lomustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This causes shrinkage of tumor cells and thereby prevents the growth and further spread of cancerous or non-cancerous cells.

How Lomoother 40 Capsule Works

Lomoother 40 Capsule contains Lomustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This causes shrinkage of tumor cells and thereby prevents the growth and further spread of cancerous or non-cancerous cells.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lomoother 40 Capsule

  • Nausea
  • Dizziness
  • Headache
  • Vomiting
  • Lack of energy
  • Visual disturbances
  • Loss of balance
  • Difficulty talking
  • Decreased platelet count
  • Blindness

What if I have taken an overdose of Lomoother 40 Capsule

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Lomoother 40 Capsule may include black or tarry stools, diarrhoea, sore throat, cough, fever, dizziness, other signs of infection, red urine, shortness of breath, stomach pain, sores in the mouth and throat, unusual bruising or bleeding, unusual tiredness or weakness, and vomiting. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Lomoother 40 Capsule should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. This medicine can cause a severe decrease in the number of blood cells in your bone marrow. A decrease in the number of blood cells in your body may cause certain symptoms and increase the risk of developing a serious infection or bleeding. Before administration, inform your doctor if you have liver/kidney disease, blood disorders, or respiratory conditions. Lomoother 40 Capsule may cause pulmonary toxicity, delayed myelosuppression, pulmonary fibrosis, secondary malignancies, nephrotoxicity, and hepatotoxicity in some patients. Hence, careful monitoring should be done during the entire treatment. Lomoother 40 Capsule is known to cause embryo-fetal harm in pregnant women. Hence, inform your doctor if you are pregnant or are planning to become pregnant. Breastfeeding should be discontinued in nursing mothers during the treatment. Lomoother 40 Capsule should be given in children only if prescribed by the paediatrician. Avoid alcohol consumption and smoking, as it can lead to serious adverse effects. Lomoother 40 Capsule may cause visual disturbances as a side effect. Hence, avoid driving vehicles or operating machines until you can see clearly. Lomoother 40 Capsule should be taken once in 6 weeks only. Hence, talk to your doctor or pharmacist before starting the treatment.

Drug-Drug Interactions

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LomustineInfliximab
Severe
LomustineEtanercept
Severe

Drug-Drug Interactions

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LomustineInfliximab
Severe
How does the drug interact with Lomoother 40 Capsule 6's:
Combining Infliximab with Lomoother 40 Capsule 6's can increase the risk or severity of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Infliximab and Lomoother 40 Capsule 6's, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, losing weight, or experiencing pain or burning while urinating, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
LomustineEtanercept
Severe
How does the drug interact with Lomoother 40 Capsule 6's:
When Etanercept is used with Lomoother 40 Capsule 6's, the likelihood or severity of infection may increase.

How to manage the interaction:
There may be a possibility of interaction between Etanercept and Lomoother 40 Capsule 6's, but it can be taken if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
LomustineBaricitinib
Severe
How does the drug interact with Lomoother 40 Capsule 6's:
Using baricitinib together with Lomoother 40 Capsule 6's may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Baricitinib and Lomoother 40 Capsule 6's, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms - fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination - consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • After your treatment begins, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals to take during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans, and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast and fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Lomoother 40 Capsule Substitute

Substitutes safety advice
  • MOOSTIN 40MG TABLET

    by Others

    129.60per tablet
  • Estine Capsule 10's

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    101.20per tablet
  • Lomcap 40 Capsule 10's

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    127.80per tablet
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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Lomoother 40 Capsule to prevent serious adverse effects.

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Pregnancy

Unsafe

Lomoother 40 Capsule is not recommended for use in pregnancy as it may harm your fetus. If you are pregnant or planning pregnancy, inform your doctor before taking Lomoother 40 Capsule.

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Breast Feeding

Unsafe

Avoid breastfeeding your child while on treatment with Lomoother 40 Capsule as it causes serious side effects to the baby.

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Driving

Unsafe

Lomoother 40 Capsule may cause visual disturbances as a side effect. Avoid driving vehicles or operating machines until you are alert.

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Liver

Caution

Lomoother 40 Capsule may cause hepatotoxicity. If you have a pre-existing or a history of liver disease, inform your doctor before taking Lomoother 40 Capsule. Your liver function should be monitored carefully before, during and after the treatment with Lomoother 40 Capsule.

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Kidney

Caution

Lomoother 40 Capsule and its metabolites are known to be largely eliminated via the kidney, and the risk of adverse responses to this medicine may be higher in patients with impaired renal function. It may cause nephrotoxicity with progressive renal failure and a decrease in kidney size. Hence, if you have a pre-existing or a history of kidney disease, inform your doctor before taking Lomoother 40 Capsule.

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Children

Caution

Please consult a doctor. Your child's doctor may recommend this medicine based on the age, body weight and disease condition of your child.

FAQs

Lomoother 40 Capsule is used to treat Brain Tumors and Hodgkin's Disease.
Lomoother 40 Capsule contains Lomustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis.
Lomoother 40 Capsule may cause or worsen pulmonary toxicity, myelosuppression, nephrotoxicity and hepatotoxicity. Hence, inform your oncologist about your complete medical history, including current medication, to rule out any adverse effects/interactions.
Lomoother 40 Capsule is effective in treating brain tumours and Hodgkin's lymphoma (a rare type of blood cancer that affects the lymphatic system). However, its effectiveness can vary depending on the type and stage of cancer, how the body responds to the medication, and whether it is used alone or in combination with other anti-cancer drugs. Always follow your doctor's instructions, as proper dosing and monitoring are crucial for maximizing its effectiveness.
Lomoother 40 Capsule does not work immediately. It may take several weeks or months to see the full effect of the treatment as the drug gradually slows the growth of cancer cells. Your doctor will monitor your progress and adjust your treatment plan accordingly.
Lomoother 40 Capsule has a long half-life, typically 16 to 48 hours, meaning it can remain in your body for several days. However, its effects can last longer, as it works in the body for weeks.
If you miss a dose of Lomoother 40 Capsule, take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose and take your next dose at the usual time. Do not take two doses at once to make up for a missed dose. Always follow your doctor's instructions for dosing.
Lomoother 40 Capsule may cause common side effects, such as nausea, vomiting, headache, visual disturbances, blindness, disorientation, lack of energy, loss of control, and difficulty talking in some individuals. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Before taking Lomoother 40 Capsule, it's important to share your medical history and current medications with your doctor. If you have any allergies, liver or kidney problems, or breathing issues, be sure to let them know. Lomoother 40 Capsule can lower your blood count, making you more prone to infections or bleeding, and may cause vision problems, so be careful when driving or operating machinery. Additionally, if you're pregnant or breastfeeding, inform your doctor, and children should only take Lomoother 40 Capsule under a paediatrician's care. Typically taken every 6 weeks, be sure to consult your doctor or pharmacist before starting treatment.
Yes, women can use Lomoother 40 Capsule only if recommended by a doctor. Lomoother 40 Capsule is a chemotherapy drug, and its use may require special considerations for women, particularly those who are pregnant, breastfeeding, or planning to become pregnant. This is because it can harm the developing foetus or be passed to the baby through breast milk. Always consult with your doctor before using Lomoother 40 Capsule. Your doctor will evaluate the benefits and risks before prescribing it and may monitor you for any side effects.

Country of origin

India

Manufacturer/Marketer address

Plot No'S : 118 - 120, Road No.6, Aleap Ie, Pragathi Nagar, Gajularamaram Village, Kukatpally, Hyderabad ,Telangana - 500 072, India.
Other Info - LOM0100

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