Lisr 300 mg PR Tablet is used to prevent and treat mood disorders like mania and bipolar disorder. Mania is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Bipolar disorder is a mental condition associated with extreme mood swings ranging from the hyper stage of mania to low-mood depression.

Lisr 300 mg PR Tablet contains Lithium that helps to treat mental disorders by increasing the activity of chemical messengers in the brain, thereby suppressing the excessive and abnormal activity of nerve cells in the brain and helping in stabilizing a person’s mood.

Take Lisr 300 mg PR Tablet as prescribed. Your doctor will advise how often you take Lisr 300 mg PR Tablet based on your medical condition. Some people may experience loss of appetite, dizziness, dry mouth, taste change, diarrhoea, blurred vision, slurred speech, shaky movements, increased thirst, and urination. Most of these side effects of Lisr 300 mg PR Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Lisr 300 mg PR Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Lisr 300 mg PR Tablet . Regular blood tests are recommended while taking Lisr 300 mg PR Tablet to monitor the levels of lithium in blood. If you have fits, kidney or heart problems, thyroid, persistent headache, vision problems, and if you are planning or have had weight loss surgery, please inform your doctor before taking Lisr 300 mg PR Tablet .

Lisr 300 mg PR Tablet is a mood stabilizer that is used to prevent and treat mood disorders such as mania and bipolar disorder. Lisr 300 mg PR Tablet contains Lithium that helps to treat mental disorders by increasing the activity of chemical messengers in the brain, thereby suppressing the excessive and abnormal activity of nerve cells in the brain and helping in stabilizing a person’s mood. Thus, Lisr 300 mg PR Tablet relaxes nerves and calms the mood, which helps in having a better social life and enables one to do daily activities comfortably.

• Loss of appetite
• Dizziness
• Dry mouth
• Taste change
• Diarrhoea
• Blurred vision
• Slurred speech
• Shaky movements
• Increased thirst and urination

Regular blood tests are recommended while taking Lisr 300 mg PR Tablet to check lithium levels in blood. If you are pregnant or breastfeeding, please inform your doctor before taking Lisr 300 mg PR Tablet . If you have hypothyroidism (underactive thyroid gland), please inform your doctor before taking Lisr 300 mg PR Tablet as it may cause low thyroid levels. If you notice decreased amount of urine, dark, reddish urine, muscle pain or weakness, inform your doctor immediately as it may be due to a serious condition called rhabdomyolysis (muscle tissue breakdown) which may lead to kidney problems.

Drug-Drug Interaction: Lisr 300 mg PR Tablet may have interaction with high blood pressure-lowering medicines (ramipril, lisinopril, methyldopa, amlodipine, diltiazem), pain killers (ibuprofen, diclofenac, celecoxib, indomethacin), asthma drugs (theophylline), antipsychotics (olanzapine, haloperidol, clozapine, sertindole), fits related drugs (phenytoin, clonazepam, carbamazepine), heart-related medicines (quinidine, amiodarone, propafenone, ranolazine, procainamide, disopyramide, ajmaline, cibenzoline, hydroquinidine, azimilide, ibutilide, sotalol, dofetilide), antidepressants (paroxetine, amitriptyline, fluoxetine), antibiotics (trimethoprim, spectinomycin, co-trimoxazole, metronidazole, tetracyclines).

Drug-Food Interaction: Lisr 300 mg PR Tablet may interact with caffeine. Therefore, reduce the intake of caffeine including coffee, tea or herbal medicines as it may decrease the effect of Lisr 300 mg PR Tablet . Also, avoid alcohol intake as it may increase side effects such as drowsiness, dizziness or difficulty in concentrating. Intake of sodium may also alter lithium levels. Hence, maintain a constant dietary intake of salt.

Drug-Disease Interaction: If you have fits, kidney or heart problems, thyroid, persistent headache, vision problems, Brugada syndrome (a hereditary syndrome affecting the heart), hypothyroidism (low thyroid levels) and low sodium levels, inform your doctor before taking Lisr 300 mg PR Tablet .

• RAMIPRIL
• LISINOPRIL
• METHYLDOPA
• AMLODIPINE
• DILTIAZEM
• IBUPROFEN
• DICLOFENAC
• CELECOXIB
• INDOMETHACIN
• THEOPHYLLINE
• OLANZAPINE
• HALOPERIDOL
• CLOZAPINE
• SERTINDOLE
• PHENYTOIN
• CLONAZEPAM
• CARBAMAZEPINE
• QUINIDINE
• AMIODARONE
• PROPAFENONE
• RANOLAZINE
• PROCAINAMIDE
• DISOPYRAMIDE
• HYDROQUINIDINE
• IBUTILIDE
• SOTALOL
• DOFETILIDE
• PAROXETINE
• AMITRIPTYLINE
• FLUOXETINE
• TRIMETHOPRIM
• SPECTINOMYCIN
• METRONIDAZOLE
• TETRACYCLINE

• Avoid low-sodium diet as it may increase lithium levels in blood and cause adverse effects.
• Limit the intake of caffeine as it may reduce the effectiveness of Lisr 300 mg PR Tablet .
• Do regular exercise and maintain a stable weight as Lisr 300 mg PR Tablet may cause weight gain.
• Drink plenty of water to avoid dehydration and try to drink same amount of water everyday as any major changes in quantity may affect lithium levels.
• Avoid consumption of alcohol as it may increase drowsiness.

• Regular blood tests are advised every week while taking Lisr 300 mg PR Tablet to monitor the levels of lithium in blood. When lithium levels are constant, blood tests may be done for every 3 months.

• Drink constant amount of water daily and maintain a constant sodium intake as any major changes in these two may alter the levels of lithium in blood.

Mania: It is a mental condition which causes intense excitement, high energy and delusions (misbeliefs). Mania may occur due to lack of sleep or changes in sleep patterns, high levels of stress and alcohol intake. Seek medical help immediately if you have any self-harming or suicidal thoughts. Bipolar disorder, also called manic depression, is a mental condition associated with extreme mood swings ranging from manic highs to depressive lows. The symptoms of bipolar disorder include mania (high energy and excitability) and depression (loss of interest, hopelessness, low energy). Bipolar disorder involves lifelong treatment.