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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Lisr 300 mg PR Tablet is used to prevent and treat mood disorders like mania and bipolar disorder. It contains Lithium, which helps to treat mental disorders by increasing the activity of chemical messengers in the brain, thereby suppressing the excessive and abnormal activity of nerve cells in the brain and helping in stabilizing a person's mood. Some people may experience loss of appetite, dizziness, dry mouth, taste change, diarrhoea, blurred vision, slurred speech, shaky movements, increased thirst, and urination. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

LITHIUM-300MG

Manufacturer/Marketer :

Alteus Biogenics Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Lisr 300 mg PR Tablet

Lisr 300 mg PR Tablet is used to prevent and treat mood disorders like mania and bipolar disorder. Mania is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Bipolar disorder is a mental condition associated with extreme mood swings ranging from the hyper stage of mania to low-mood depression.

Lisr 300 mg PR Tablet contains Lithium that helps to treat mental disorders by increasing the activity of chemical messengers in the brain, thereby suppressing the excessive and abnormal activity of nerve cells in the brain and helping in stabilizing a person’s mood.

Take Lisr 300 mg PR Tablet as prescribed. Your doctor will advise how often you take Lisr 300 mg PR Tablet based on your medical condition. Some people may experience loss of appetite, dizziness, dry mouth, taste change, diarrhoea, blurred vision, slurred speech, shaky movements, increased thirst, and urination. Most of these side effects of Lisr 300 mg PR Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Lisr 300 mg PR Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Lisr 300 mg PR Tablet . Regular blood tests are recommended while taking Lisr 300 mg PR Tablet to monitor the levels of lithium in blood. If you have fits, kidney or heart problems, thyroid, persistent headache, vision problems, and if you are planning or have had weight loss surgery, please inform your doctor before taking Lisr 300 mg PR Tablet .

Uses of Lisr 300 mg PR Tablet

Treatment of Bipolar disorder, Mania.

Directions for Use

Take Lisr 300 mg PR Tablet as prescribed by your doctor.

Medicinal Benefits

Lisr 300 mg PR Tablet is a mood stabilizer that is used to prevent and treat mood disorders such as mania and bipolar disorder. Lisr 300 mg PR Tablet contains Lithium that helps to treat mental disorders by increasing the activity of chemical messengers in the brain, thereby suppressing the excessive and abnormal activity of nerve cells in the brain and helping in stabilizing a person’s mood. Thus, Lisr 300 mg PR Tablet relaxes nerves and calms the mood, which helps in having a better social life and enables one to do daily activities comfortably.

How Lisr 300 mg PR Tablet Works

Lisr 300 mg PR Tablet contains Lithium that helps to treat mental disorders by increasing the activity of chemical messengers in the brain, thereby suppressing the excessive and abnormal activity of nerve cells in the brain and helping in stabilizing a person’s mood.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lisr 300 mg PR Tablet

  • Loss of appetite
  • Dizziness
  • Dry mouth
  • Taste change
  • Diarrhoea
  • Blurred vision
  • Slurred speech
  • Shaky movements
  • Increased thirst and urination

What if I have taken an overdose of Lisr 300 mg PR Tablet

Do not take more than the prescribed dose of Lisr 300 mg PR Tablet as too much Lithium may be dangerous. The symptoms include blurred vision, feeling or being sick, vomiting, fainting, sleepiness, lightheadedness, increased urge to urinate, lack of control over pee or poo, shaking or muscle weakness, muscle twitches, spasms or jerks affecting the face, eyes, neck or tongue, confusion and blackouts. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Regular blood tests are recommended while taking Lisr 300 mg PR Tablet to check lithium levels in blood. If you are pregnant or breastfeeding, please inform your doctor before taking Lisr 300 mg PR Tablet . If you have hypothyroidism (underactive thyroid gland), please inform your doctor before taking Lisr 300 mg PR Tablet as it may cause low thyroid levels. If you notice decreased amount of urine, dark, reddish urine, muscle pain or weakness, inform your doctor immediately as it may be due to a serious condition called rhabdomyolysis (muscle tissue breakdown) which may lead to kidney problems.

Drug-Drug Interactions

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LithiumCidofovir
Critical
LithiumCisapride
Critical

Drug-Drug Interactions

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LithiumCidofovir
Critical
How does the drug interact with Lisr 300 mg PR Tablet 15's:
Cidofovir can cause higher levels of Lisr 300 mg PR Tablet 15's carbonate in the blood which increases risk of kidney problems.

How to manage the interaction:
Taking Lisr 300 mg PR Tablet 15's with Cidofovir is not recommended, but can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
LithiumCisapride
Critical
How does the drug interact with Lisr 300 mg PR Tablet 15's:
Taking Cisapride with Lisr 300 mg PR Tablet 15's can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Lisr 300 mg PR Tablet 15's with Cisapride is not recommended as it can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
LithiumSodium Valproate
Severe
How does the drug interact with Lisr 300 mg PR Tablet 15's:
Co-administration of Lisr 300 mg PR Tablet 15's with sodium valproate can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lisr 300 mg PR Tablet 15's and sodium valproate can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
LithiumVortioxetine
Severe
How does the drug interact with Lisr 300 mg PR Tablet 15's:
Taking Vortioxetine with Lisr 300 mg PR Tablet 15's may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a interaction between Vortioxetine and Lisr 300 mg PR Tablet 15's, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
LithiumVilazodone
Severe
How does the drug interact with Lisr 300 mg PR Tablet 15's:
Co-administration Vilazodone with Lisr 300 mg PR Tablet 15's may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a interaction between Vilazodone and Lisr 300 mg PR Tablet 15's, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
LithiumBedaquiline
Severe
How does the drug interact with Lisr 300 mg PR Tablet 15's:
Taking amisulpride together with tamoxifen can increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Lisr 300 mg PR Tablet 15's and Bedaquiline, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.
LithiumEscitalopram
Severe
How does the drug interact with Lisr 300 mg PR Tablet 15's:
Taking Lisr 300 mg PR Tablet 15's together with Escitalopram can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Escitalopram with Lisr 300 mg PR Tablet 15's together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.
LithiumCeritinib
Severe
How does the drug interact with Lisr 300 mg PR Tablet 15's:
Taking Lisr 300 mg PR Tablet 15's together with Ceritinib can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Ceritinib with Lisr 300 mg PR Tablet 15's can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.
LithiumEnalapril
Severe
How does the drug interact with Lisr 300 mg PR Tablet 15's:
Taking Lisr 300 mg PR Tablet 15's with Enalapril may significantly increase the blood levels of Lisr 300 mg PR Tablet 15's.

How to manage the interaction:
Co-administration of Enalapril with Lisr 300 mg PR Tablet 15's can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience drowsiness, dizziness, loose stools, vomiting, muscle weakness, shaking of hands and legs, excessive thirst, and increased urination. Do not discontinue any medications without consulting a doctor.
LithiumTramadol
Severe
How does the drug interact with Lisr 300 mg PR Tablet 15's:
Taking tramadol with Lisr 300 mg PR Tablet 15's can increase the risk of seizures(fits).

How to manage the interaction:
Co-administration of tramadol along with Lisr 300 mg PR Tablet 15's can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience any unusual symptoms like staring, stiffening of the legs and hands, stiffening of body, loss of consciousness, breathing difficulties , lack of urinary or bowel control, and Falling suddenly for no apparent reason, contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid low-sodium diet as it may increase lithium levels in blood and cause adverse effects.
  • Limit the intake of caffeine as it may reduce the effectiveness of Lisr 300 mg PR Tablet .
  • Do regular exercise and maintain a stable weight as Lisr 300 mg PR Tablet may cause weight gain.
  • Drink plenty of water to avoid dehydration and try to drink same amount of water everyday as any major changes in quantity may affect lithium levels.
  • Avoid consumption of alcohol as it may increase drowsiness.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

Lisr 300 mg PR Tablet Substitute

Substitutes safety advice
  • Lithosun 300 Tablet 10's

    2.43per tablet
  • Licab Tablet 10's

    2.43per tablet
  • T Lith Cr-300 Tablet 10's

    6.30per tablet
  • Intalith 300 mg Tablet 10's

    by AYUR

    1.62per tablet
  • Lithonex-300 Tablet 10's

    1.62per tablet
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Lisr 300 mg PR Tablet as it may increase the risk of side effects such as drowsiness, dizziness or difficulty in concentrating.

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Pregnancy

Unsafe

Lisr 300 mg PR Tablet is a Category D pregnancy drug and is not recommended for use during pregnancy as it may cause harm to the unborn baby.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Lisr 300 mg PR Tablet as it may be excreted in breast milk and cause adverse effects in the baby.

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Driving

Unsafe

Lisr 300 mg PR Tablet may cause dizziness, drowsiness or other severe adverse effects. Therefore, avoid driving if you feel drowsy or dizzy after taking Lisr 300 mg PR Tablet .

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Liver

Safe if prescribed

Lisr 300 mg PR Tablet is safe to use in patients with Liver diseases/conditions if prescribed by a doctor.

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Kidney

Caution

Take Lisr 300 mg PR Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Lisr 300 mg PR Tablet is not recommended for patients with severe kidney problems.

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Children

Caution

Lisr 300 mg PR Tablet is generally not recommended for children below 12 years. However, Lisr 300 mg PR Tablet may be used in children above 7 years for treating bipolar I disorder only if prescribed by a doctor.

FAQs

Lisr 300 mg PR Tablet is used to prevent and treat mood disorders like mania and bipolar disorder. It works by increasing the activity of chemical messengers in the brain, thereby suppressing the excessive and abnormal activity of nerve cells in the brain and helping to stabilize a person’s mood.
No, you are not recommended to take Lisr 300 mg PR Tablet with fluoxetine or other antidepressants such as paroxetine and sertraline as co-administration of these medicines may increase the risk of a rare and serious condition known as serotonin syndrome. If you experience blurred vision, increased heart rate, hallucination, fits, confusion, muscle stiffness or spasm, vomiting, nausea, diarrhoea, excessive sweating, stomach cramps, fever, shaking or shivering, please consult a doctor immediately. However, before using Lisr 300 mg PR Tablet with any other medicines, you are advised to contact your doctor.
Lisr 300 mg PR Tablet is not recommended for hypothyroid (underactive thyroid gland) patients as it may increase the risk of low levels of thyroid hormone. Therefore, if you have hypothyroidism, please inform your doctor before taking Lisr 300 mg PR Tablet . Also, thyroid levels are checked generally before starting treatment with Lisr 300 mg PR Tablet so that if the levels are too low, Lisr 300 mg PR Tablet is not advised.
Yes, Lisr 300 mg PR Tablet may cause weight gain but it is not necessary for everyone taking Lisr 300 mg PR Tablet to experience this side effect. However, in order to avoid gaining weight while taking Lisr 300 mg PR Tablet , you are advised to do regular exercise and avoid high-calorie drinks. Instead take non-alcoholic drinks, herbal tea and lemon water.
It is advised to inform your doctor if you are planning or had weight loss surgery as the dose may be adjusted accordingly based on lithium levels in blood.
Yes, Lisr 300 mg PR Tablet may cause dehydration especially if you have low sodium levels in the body or consume too much alcohol. However, if you notice dark, strong smelling urine or decrease in urination, it indicates that you are dehydrated and may affect lithium levels in blood. Therefore, you are recommended to drink plenty of fluids while taking Lisr 300 mg PR Tablet to avoid dehydration.
No, you are not recommended to stop taking Lisr 300 mg PR Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Lisr 300 mg PR Tablet for as long as your doctor has prescribed it and if you experience any difficulty while taking Lisr 300 mg PR Tablet , please consult your doctor so that the dose may be gradually reduced.
Lisr 300 mg PR Tablet may cause side effects such as slurred speech, confusion, mood changes, bloating, or lightheadedness. If these side effects persist or worsen, please consult your doctor.
Lisr 300 mg PR Tablet takes some time to show improvement in your symptoms but it varies from person to person. This is because each patient reacts differently to particular medication. It may take 1 to 3 weeks or longer for you to see the full effects of Lisr 300 mg PR Tablet . Continue taking Lisr 300 mg PR Tablet even if you are not improving and consult your doctor.
Yes, Lisr 300 mg PR Tablet can cause drowsiness or sleepiness. If you feel dizzy or sleepy, avoid driving or using machines or performing any tasks that require your attention.
Yes, Lisr 300 mg PR Tablet may cause kidney problems. Lisr 300 mg PR Tablet is not advised in patients who already have severe kidney impairment. Before starting treatment with Lisr 300 mg PR Tablet , your doctor will recommend blood tests to see if your kidney function is normal. During treatment with Lisr 300 mg PR Tablet , any gradual or sudden changes in kidney function, may indicate that the treatment needs re-evaluation.
Lisr 300 mg PR Tablet should only be started if sufficient facilities are available for evaluating Lisr 300 mg PR Tablet levels as increased blood levels of Lisr 300 mg PR Tablet is related to Lisr 300 mg PR Tablet toxicity. Even at dose which is effective for treatment, Lisr 300 mg PR Tablet toxicity can occur. Therefore, your doctor may closely monitor your Lisr 300 mg PR Tablet levels weekly until stabilization is reached, then weekly for one month and then every month after that.
Take Lisr 300 mg PR Tablet with or without food or as advised by the doctor. Swallow it as whole with a glass of water. Do not break, crush or chew it.
Some medicines decrease Lisr 300 mg PR Tablet levels in blood which means that it will not work well. These include caffeine, theophylline (for asthma), medicines containing sodium bicarbonate, or a special group of diuretics (water tablets) called carbonic anhydrase inhibitors and urea (used to treat skin conditions). Therefore, please inform your doctor about the medicines you are taking before starting Lisr 300 mg PR Tablet to avoid drug interactions.

Country of origin

India

Manufacturer/Marketer address

Alteus Biogenics Pvt. Ltd., 14-B Dover Lane, Kolkata - 700029, Wb, India.
Other Info - LIS0082

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