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  3. Lidowel CR 450 Tablet 10's

Lidowel CR 450 Tablet 10's, Pack of 10 TabletS
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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Lidowel CR 450 Tablet belongs to the class of antipsychotic medicine used in the treatment of bipolar disorder and mania. This medicine suppresses the excess and abnormal activity of nerve cells in the brain by increasing the activity of chemical messengers in the brain. Common side effects include loss of appetite, dizziness, dry mouth, taste change, diarrhoea, blurred vision, slurred speech, shaky movements, increased thirst, and urination.
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Composition :

LITHIUM CARBONATE-450MG

Manufacturer/Marketer :

Sigmund Promedica

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Lidowel CR 450 Tablet

Lidowel CR 450 Tablet belongs to a psychological class of drugs called 'anti-manic agents' or 'mood stabilizers' primarily used to prevent and treat mood disorders like mania and bipolar disorder. Mania is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Bipolar disorder is a mental condition associated with extreme mood swings ranging from the hyper stage of mania to low mood depression.

Lidowel CR 450 Tablet contains Lithium carbonate that helps to treat mental disorders by increasing the activity of chemical messengers in the brain; thereby, suppressing the excessive and abnormal activity of nerve cells in the brain and helping in stabilizing a person’s mood.

Take Lidowel CR 450 Tablet as prescribed. Your doctor will advise you on how often you need to take Lidowel CR 450 Tablet based on your medical condition. Some people may experience loss of appetite, dizziness, dry mouth, taste change, diarrhoea, blurred vision, slurred speech, shaky movements, increased thirst, and urination. Most of these side effects of Lidowel CR 450 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Lidowel CR 450 Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Lidowel CR 450 Tablet . Regular blood tests are recommended while taking Lidowel CR 450 Tablet to monitor the levels of lithium in blood. If you have fits, kidney or heart problems, thyroid, persistent headache, vision problems, and if you are planning or had weight loss surgery, please inform your doctor before taking Lidowel CR 450 Tablet .

Uses of Lidowel CR 450 Tablet

Treatment of Bipolar disorder and Mania

Directions for Use

Take Lidowel CR 450 Tablet with food for better absorption or take it as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Lidowel CR 450 Tablet is a mood stabilizer that is used to prevent and treat mood disorders such as mania and bipolar disorder. Lidowel CR 450 Tablet contains Lithium carbonate that helps to treat mental disorders by increasing the activity of chemical messengers in the brain; thereby, suppressing the excessive and abnormal activity of nerve cells in the brain and helping in stabilizing a person’s mood. Thus, Lidowel CR 450 Tablet relaxes nerves and calms the mood, which helps in having a better social life and enables to do daily activities comfortably.

How Lidowel CR 450 Tablet Works

Lidowel CR 450 Tablet contains Lithium carbonate that helps to treat mental disorders by increasing the activity of chemical messengers in the brain; thereby, suppressing the excessive and abnormal activity of nerve cells in the brain and helping in stabilizing a person’s mood.

Storage

Store in a cool and dry place away from sunlight
Side effects of Lidowel CR 450 Tablet
  • Incorporate foods high in antioxidants, such as tomatoes, leafy greens, and berries, to prevent inflammation.
  • Encourage stress-relieving activities like yoga, deep breathing, and meditation.
  • Support the immune system and help the body rid itself of toxins.
  • Regularly check white blood cell counts to monitor the effectiveness of therapy and make any necessary modifications.
  • Reduce fluid intake 2-3 hours prior to bedtime.
  • Limit alcohol and caffeine as they can increase urination and affect bladder health.
  • Maintain sleep hygiene.
  • Eat a low-salt and healthy diet.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Muscle weakness can be due to tiredness, which can be managed by eating often.
  • Observe your movements and understand why the muscle is weakening.
  • Regularly do strengthening exercises to improve blood flow throughout the body and reduce weakness.
  • Sleep well and give enough rest to your body.
  • Take a balanced diet, quit smoking and intake of alcohol.
  • Practice yoga and meditation to improve inner strength and stay healthy.

What if I have taken an overdose of Lidowel CR 450 Tablet

Take Lidowel CR 450 Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include vomiting, diarrhoea, muscular weakness, drowsiness, and lack of coordination. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Regular blood tests are recommended while taking Lidowel CR 450 Tablet to check lithium levels in the blood. If you are pregnant or breastfeeding, please inform your doctor before taking Lidowel CR 450 Tablet . If you have hypothyroidism (underactive thyroid gland), please inform your doctor before taking Lidowel CR 450 Tablet as it may cause low thyroid levels. If you notice decreased amount of urine, dark, reddish urine, muscle pain or weakness, inform your doctor immediately as it may be due to a serious condition called rhabdomyolysis (muscle tissue breakdown) which may lead to kidney problems.

Drug-Drug Interactions

verifiedApollotooltip
LithiumCisapride
Critical
LithiumCidofovir
Critical

Drug-Drug Interactions

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LithiumCisapride
Critical
How does the drug interact with Lidowel CR 450 Tablet:
Taking Cisapride with Lidowel CR 450 Tablet can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Lidowel CR 450 Tablet with Cisapride is not recommended as it can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
LithiumCidofovir
Critical
How does the drug interact with Lidowel CR 450 Tablet:
Cidofovir can cause higher levels of Lidowel CR 450 Tablet carbonate in the blood which increases risk of kidney problems.

How to manage the interaction:
Taking Lidowel CR 450 Tablet with Cidofovir is not recommended, but can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
LithiumFlurbiprofen
Severe
How does the drug interact with Lidowel CR 450 Tablet:
Co-administration of Flurbiprofen with Lidowel CR 450 Tablet may significantly increase the blood levels of Lidowel CR 450 Tablet.

How to manage the interaction:
There may be a possibility of interaction between Flurbiprofen and Lidowel CR 450 Tablet, but it can be taken if prescribed by a doctor. However, if you experience drowsiness, dizziness, confusion, loose stools, vomiting, muscle weakness, muscle incoordination, shaking of hands and legs, blurred vision, ringing in the ear, excessive thirst and increased urination contact your doctor immediately. Do not stop using any medications without a doctor's advice.
LithiumFluvoxamine
Severe
How does the drug interact with Lidowel CR 450 Tablet:
Taking Lidowel CR 450 Tablet with Fluvoxamine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a interaction between Fluvoxamine and Lidowel CR 450 Tablet, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
LithiumCitalopram
Severe
How does the drug interact with Lidowel CR 450 Tablet:
Taking Lidowel CR 450 Tablet with Citalopram can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a interaction between Citalopram and Lidowel CR 450 Tablet, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
LithiumMoexipril
Severe
How does the drug interact with Lidowel CR 450 Tablet:
Taking Lidowel CR 450 Tablet with Moexipril may significantly increase the blood levels of Lidowel CR 450 Tablet.

How to manage the interaction:
Co-administration of Lidowel CR 450 Tablet with Moexipril can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience drowsiness, dizziness, confusion, loose stools, vomiting, muscle weakness, muscle incoordination, shaking of hands and legs, blurred vision, ringing in the ear, excessive thirst, or increased urination contact a doctor. Do not stop using any medications without a doctor's advice.
LithiumSpironolactone
Severe
How does the drug interact with Lidowel CR 450 Tablet:
Taking Lidowel CR 450 Tablet and spironolactone may increase blood levels of Lidowel CR 450 Tablet.

How to manage the interaction:
Although taking spironolactone and Lidowel CR 450 Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as loose stools, vomiting, drowsiness, shaking, thirst, lack of coordination, or muscle weakness. Do not stop using any medications without consulting doctor.
LithiumAmisulpride
Severe
How does the drug interact with Lidowel CR 450 Tablet:
Taking amisulpride with Lidowel CR 450 Tablet increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking amisulpride along with Lidowel CR 450 Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
LithiumHaloperidol
Severe
How does the drug interact with Lidowel CR 450 Tablet:
Coadministration of Haloperidol with Lidowel CR 450 Tablet can increase the levels and risk of developing Lidowel CR 450 Tablet side effects.

How to manage the interaction:
Although taking Haloperidol and Lidowel CR 450 Tablet together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience tiredness, dizziness, confusion, difficulty breathing, an irregular heartbeat, weakness, or fever, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LithiumIndapamide
Severe
How does the drug interact with Lidowel CR 450 Tablet:
Taking Indapamide with Lidowel CR 450 Tablet can increase the blood levels of Lidowel CR 450 Tablet.

How to manage the interaction:
Taking Indapamide with Lidowel CR 450 Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms like loose stools, vomiting, drowsiness, shaking of hands and legs, thirst, increased urination, lack of coordination, or muscle weakness, consult a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a constant sodium diet as it may affect lithium levels in the blood and cause adverse effects.
  • Limit the intake of caffeine as it may reduce the effectiveness of Lidowel CR 450 Tablet .
  • Do regular exercise and maintain a stable weight as Lidowel CR 450 Tablet may cause weight gain.
  • Drink plenty of water to avoid dehydration and try to drink the same amount of water every day as any major changes in quantity may affect lithium levels.
  • Avoid consumption of alcohol as it may increase drowsiness.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

Lidowel CR 450 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Lidowel CR 450 Tablet as it may increase the risk of side effects such as drowsiness, dizziness or difficulty in concentrating.

bannner image

Pregnancy

Unsafe

Lidowel CR 450 Tablet is a Category D pregnancy drug and is not recommended for use during pregnancy as it may cause harm to the unborn baby.

bannner image

Breast Feeding

Unsafe

Avoid breastfeeding while taking Lidowel CR 450 Tablet as it may be excreted in breast milk and cause adverse effects in the baby.

bannner image

Driving

Unsafe

Lidowel CR 450 Tablet may cause dizziness, drowsiness or other severe adverse effects. Therefore, avoid driving if you feel drowsy or dizzy after taking Lidowel CR 450 Tablet .

bannner image

Liver

Safe if prescribed

Lidowel CR 450 Tablet is safe to use in patients with liver diseases/conditions if prescribed by a doctor.

bannner image

Kidney

Caution

Take Lidowel CR 450 Tablet with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required. Lidowel CR 450 Tablet is not recommended for patients with severe kidney problems.

bannner image

Children

Caution

Lidowel CR 450 Tablet is generally not recommended for children below 12 years. However, Lidowel CR 450 Tablet may be used in children above 7 years for treating bipolar disorder only if prescribed by a doctor.

Have a query?

FAQs

Lidowel CR 450 Tablet belongs to a psychological class of drugs called 'anti-manic agents' or 'mood stabilizers' primarily used to prevent and treat mood disorders like mania and bipolar disorder.

Lidowel CR 450 Tablet helps to treat mental disorders by increasing the activity of chemical messengers in the brain; thereby, suppressing the excessive and abnormal activity of nerve cells in the brain and helping in stabilizing a person’s mood.

Lidowel CR 450 Tablet is not recommended for hypothyroid (underactive thyroid gland) patients as it may increase the risk of low levels of thyroid hormone. Therefore, if you have hypothyroidism, please inform your doctor before taking Lidowel CR 450 Tablet .

Lidowel CR 450 Tablet may cause weight gain but it is not necessary for everyone taking Lidowel CR 450 Tablet to experience this side effect. However, in order to avoid gaining weight while taking Lidowel CR 450 Tablet , you are advised to do regular exercise and avoid high-calorie drinks. Instead take non-alcoholic drinks, herbal tea and lemon water.

It is advised to inform your doctor if you are planning or had weight loss surgery as the dose may be adjusted accordingly based on lithium levels in blood.

Lidowel CR 450 Tablet may cause dehydration especially if you have low sodium levels in the body or consume too much alcohol. However, if you notice dark, strong-smelling urine or a decrease in urination, it indicates that you are dehydrated, and this may affect lithium levels in the blood. Therefore, you are recommended to drink plenty of fluids while taking Lidowel CR 450 Tablet to avoid dehydration.

You are not recommended to stop taking Lidowel CR 450 Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Lidowel CR 450 Tablet for as long as your doctor has prescribed it and if you experience any difficulty while taking Lidowel CR 450 Tablet , please consult your doctor so that the dose may be gradually reduced.

You are not recommended to take Lidowel CR 450 Tablet with fluoxetine or other antidepressants such as paroxetine and sertraline as co-administration of these medicines may increase the risk of a rare and serious condition known as serotonin syndrome. If you experience blurred vision, increased heart rate, hallucination, fits, confusion, muscle stiffness or spasm, vomiting, nausea, diarrhoea, excessive sweating, stomach cramps, fever, shaking, or shivering, please consult a doctor immediately. However, before using Lidowel CR 450 Tablet with any other medicines, you are advised to contact your doctor.

The effects of Lidowel CR 450 Tablet can vary from person to person, but it generally takes 1-3 weeks for you to see the full benefits. However, it's important to continue taking the Lidowel CR 450 Tablet regularly as prescribed by your doctor to maintain its effectiveness.

It's important to inform your doctor about your hypertension and the medications you're taking for it as Lidowel CR 450 Tablet can interact with certain blood pressure medications, and your doctor may need to adjust your treatment plan to ensure your safety.

No, you should not increase the dose of Lidowel CR 450 Tablet on your own. It can take 1-3 weeks to feel the full effects, and increasing the dose without medical advice can be dangerous and may lead to adverse effects. However consult your doctor if you have any concerns.

Yes, Lidowel CR 450 Tablet can cause sleepiness as a side effect. It's important to be cautious when performing activities that require alertness, such as driving or operating heavy machinery, until you know how the medication affects you.

Yes, Lidowel CR 450 Tablet can affect the kidneys. Long-term use of lithium can lead to kidney problems, and regular monitoring of kidney function is necessary during treatment. It's important to inform your doctor if you have any pre-existing kidney conditions or if you experience any symptoms of kidney problems while taking Lidowel CR 450 Tablet .

Lidowel CR 450 Tablet should only be started if adequate facilities for assessing Lidowel CR 450 Tablet levels are available. Because elevated levels of Lidowel CR 450 Tablet are linked to Lidowel CR 450 Tablet toxicity. Lidowel CR 450 Tablet toxicity can even occur at dose which is effective for treatment. Therefore, your doctor may closely monitor your Lidowel CR 450 Tablet levels weekly until stabilization is achieved, then weekly for one month and then at monthly intervals thereafter.

Lidowel CR 450 Tablet should be taken as prescribed by your doctor. It is recommended to take with food to reduce nausea. Lidowel CR 450 Tablet may be taken before or after meals. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Certain medications which decrease the levels of Lidowel CR 450 Tablet in blood include carbonic anhydrase inhibitors, chlorpromazine, sodium-containing preparations, theophylline, urea and herbal medicines. Therefore, before starting Lidowel CR 450 Tablet , inform your doctor about all the medicines you are taking.

The common side effects of Lidowel CR 450 Tablet are loss of appetite, dizziness, dry mouth, taste change, diarrhoea, blurred vision, slurred speech, shaky movements, increased thirst, and urination. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Sigma House, 43 S Wadala, Wadala West, Wadala, Mumbai, Maharashtra 400031
Other Info - LID0047

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jan 1, 2025 | 2:45 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.10828.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/017812s033,018421s032,018558s027lbl.pdf
  3. https://www.drugs.com/lithium.html
  4. https://www.nhs.uk/medicines/lithium/
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