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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Jollimine Capsule is used to treat rheumatoid arthritis, Wilson's disease, cystinuria, and lead poisoning. It contains Penicillamine which works by blocking the action of certain chemical messengers responsible for inflammation, lowering cysteine levels and facilitating the removal of extra copper in the body via urine. This medicine may sometimes cause side effects such as stomach upset, diarrhoea, change in taste, loss of appetite, mouth irritation, and mouth sores. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

PENICILLAMINE-250MG

Manufacturer/Marketer :

Jolly Healthcare

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Jollimine Capsule

Jollimine Capsule is used to treat severe rheumatoid arthritis, Wilson's disease, and cystinuria. Rheumatoid arthritis is a joint disorder in which our immune system attacks our body cells. Wilson disease is a genetic problem characterized by excess copper deposited in body parts like the eye, brain, and liver leading to metal toxicity. Cystinuria is the excess build-up of an amino acid called cystine in the urinary bladder and kidney, leading to harmful effects. 

Jollimine Capsule contains Penicillamine, which works by blocking the action of certain chemical messengers responsible for inflammation and slowing the progress of the condition with certain joint diseases. It works in Wilson's disease by binding to the extra copper in the body and causing it to leave the body through the urine. Decreasing copper levels improves liver function and mental, mood, and nerve problems (like confusion and difficulty speaking or walking) caused by Wilson's disease. Besides this, Jollimine Capsule is also used to treat cystinuria (kidney and bladder stone) and lead poisoning.

Take Jollimine Capsule exactly as prescribed by your doctor. You are advised to take Jollimine Capsule as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as protein in the urine, low blood platelets, stomach upset or throwing up, diarrhoea, change in taste, loss of appetite,  mouth irritation, and mouth sores. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Jollimine Capsule for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. Do not take Jollimine Capsule if you are pregnant or planning for pregnancy, as Jollimine Capsule causes serious congenital disabilities. Jollimine Capsule should not be taken by breastfeeding mothers as it passes into breast milk. Your doctor may advise you to undergo regular blood tests, as well as kidney and liver tests, to monitor your condition. Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.

Uses of Jollimine Capsule

Treatment of Rheumatoid arthritis, Wilson's disease, Cystinuria, and Lead poisoning.

Directions for Use

Take Jollimine Capsule as advised by the doctor. Swallow it as a whole with a glass of water; do not break, or chew it.

Medicinal Benefits

Jollimine Capsule contains Penicillamine, which is primarily used to treat Wilson's disease (copper builds up in the body and may result in serious symptoms), and cystinuria (kidney stones). It is also used in combination with other treatments to treat severe rheumatoid arthritis. The treatment of rheumatoid arthritis Jollimine Capsule reduces pain, inflammation, and slow joint damage and disease progression over time; hence Jollimine Capsule is known as a disease-modifying anti-rheumatic drug (DMARD). In Wilson's disease, Jollimine Capsule works by binding to the extra copper in the body and causing it to leave the body through the urine. Decreasing copper levels improves liver function and the mental, mood, and nerve problems (such as confusion, and difficulty speaking/walking) caused by Wilson's disease. In cystinuria, it helps decrease the amount of a certain substance (cystine) by binding to that substance which can cause kidney stones and prevent it from building up and forming stones. Besides this, Jollimine Capsule is also used to treat lead poisoning.

How Jollimine Capsule Works

Jollimine Capsule contains Penicillamine, which works by blocking the action of certain chemical messengers responsible for inflammation and slowing the progress of the condition with certain joint diseases. It works in Wilson's disease by binding to the extra copper in the body and causing it to leave the body through the urine. Decreasing copper levels improves liver function and mental, mood, and nerve problems (like confusion and difficulty speaking or walking) caused by Wilson's disease. Besides this, Jollimine Capsule is also used to treat cystinuria (kidney and bladder stone) and lead poisoning.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Jollimine Capsule

  • Protein in urine
  • Low blood platelets
  • Stomach upset 
  • Diarrhoea
  • Change in taste
  • Loss of appetite
  • Mouth irritation
  • Mouth sores

What if I have taken an overdose of Jollimine Capsule

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Do not take Jollimine Capsule if you are allergic (hypersensitive) to penicillamine or any of the other ingredients in it. Inform your doctor if you have severe kidney problems, lupus erythematosus (an auto-immune disorder), agranulocytosis (a low white cell blood count), aplastic anaemia (symptoms including feeling tired, breathless, having pale skin and more susceptible to infection) or thrombocytopenia (a blood disorder which causes bleeding into your skin, bruising and bleeding more than normal). Do not take Jollimine Capsule if you are pregnant or planning to get pregnant and breastfeeding. This medicine may cause harm to the unborn baby if you take it while you are pregnant. Caution should be required while taking Jollimine Capsule by elderly patients as they may be at greater risk of suffering side effects if you are taking Jollimine Capsule over a long time, especially if you are on a restricted diet, as this medicine increases the requirement for pyridoxine (Vitamin B6) so your doctor may also prescribe this vitamin for you. If you are taking iron tablets, antacids, or digoxin (used to treat heart failure), please maintain two hours gap between these tablets and Jollimine Capsule . Low blood cell counts have happened while taking Jollimine Capsule . If blood cell counts get very low, this can lead to bleeding problems, infections, or anaemia, and sometimes, these have been deadly. 

Drug-Drug Interactions

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PenicillamineCladribine
Severe
PenicillamineMetrizamide
Severe

Drug-Drug Interactions

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PenicillamineCladribine
Severe
How does the drug interact with Jollimine Capsule 10's:
Taking cladribine with Jollimine Capsule 10's can increase the risk of developing serious infections.

How to manage the interaction:
Taking Cladribine with Jollimine Capsule 10's together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
PenicillamineMetrizamide
Severe
How does the drug interact with Jollimine Capsule 10's:
Taking Jollimine Capsule 10's together with metrizamide can cause severe kidney problems.

How to manage the interaction:
Although taking Jollimine Capsule 10's and Metrizamide together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
PenicillamineIodamide
Severe
How does the drug interact with Jollimine Capsule 10's:
Using iodamide together with Jollimine Capsule 10's can cause an increased risk of kidney problems.

How to manage the interaction:
Although there is a drug interaction between Jollimine Capsule 10's and iodamide, they can be taken together if advised by the doctor. If you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm consult your doctor immediately. Do not discontinue medications without consulting a doctor.
PenicillamineTenofovir disoproxil
Severe
How does the drug interact with Jollimine Capsule 10's:
Coadministration of Tenofovir disoproxil with Jollimine Capsule 10's can increase the risk of developing kidney problems.

How to manage the interaction:
Taking Tenofovir disoproxil with Jollimine Capsule 10's can possibly result in an interaction, it can be taken when your doctor has advised it. However, if you experience vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, dizziness, and irregular heart rhythm contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
PenicillamineSodium aurothiomalate
Severe
How does the drug interact with Jollimine Capsule 10's:
Using Jollimine Capsule 10's together with sodium aurothiomalate can increase the severity of adverse effects of Jollimine Capsule 10's.

How to manage the interaction:
There may be a possibility of interaction between Sodium aurothiomalate and Jollimine Capsule 10's, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to your doctor.
PenicillamineLeflunomide
Severe
How does the drug interact with Jollimine Capsule 10's:
Using Jollimine Capsule 10's with leflunomide can increase the risk of low blood levels.

How to manage the interaction:
There may be a possibility of interaction between Leflunomide and Jollimine Capsule 10's, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
PenicillamineTenofovir alafenamide
Severe
How does the drug interact with Jollimine Capsule 10's:
Taking Jollimine Capsule 10's and tenofovir alafenamide can increase the risk of kidney problems.

How to manage the interaction:
Taking Jollimine Capsule 10's and Tenofovir alafenamide together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
PenicillamineDeferiprone
Severe
How does the drug interact with Jollimine Capsule 10's:
Deferiprone when taken with Jollimine Capsule 10's can cause an increased risk of low blood levels.

How to manage the interaction:
Co-administration of Jollimine Capsule 10's with Deferiprone can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
PenicillamineIoversol
Severe
How does the drug interact with Jollimine Capsule 10's:
Using ioversol together with Jollimine Capsule 10's can cause an increased risk of kidney problems.

How to manage the interaction:
Although there is a drug interaction between Jollimine Capsule 10's and ioversol, they can be taken together if advised by the doctor. If you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm consult your doctor immediately. Do not discontinue medications without consulting a doctor.
PenicillamineClozapine
Severe
How does the drug interact with Jollimine Capsule 10's:
Taking Jollimine Capsule 10's with Clozapine can increase the risk of low blood levels.

How to manage the interaction:
Taking Jollimine Capsule 10's with Clozapine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination contact your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.

  • Performing yoga may also help in improving joint flexibility and pain management.

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.

  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.

  • Acupuncture, massage and physical therapy may also be helpful.

  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.

  • Drink plenty of fluids.

  • Limit consumption of spinach, wheat bran, nuts, beets and dairy products.

  • Avoid high salt intake and foods containing baking soda.

  • Follow work safety regulations if you are at risk of occupational exposure. Wear necessary protective gear while working and do not take any contaminated material such as clothing or work gear to home. 

  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

CHELATING AGENTS

Jollimine Capsule Substitute

Substitutes safety advice
  • Cilamin-250 Capsule 10's

    14.63per tablet
  • Penicitin Capsule 10's

    14.43per tablet
  • Aaramine-250 Tablet 10's

    15.57per tablet
  • ARTAMIN 250MG CAPSULE

    15.21per tablet
  • ATRMIN 250MG CAPSULE

    13.68per tablet
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Jollimine Capsule . It could lead to increased dizziness and drowsiness.

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Pregnancy

Unsafe

Jollimine Capsule is a pregnancy category D drug. It is not recommended to take Jollimine Capsule while you are pregnant. Jollimine Capsule may cause serious birth defects.

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Breast Feeding

Unsafe

Jollimine Capsule should not be used in breastfeeding mothers as Jollimine Capsule passes into breast milk.

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Driving

Caution

Jollimine Capsule may cause dizziness, drowsiness and tiredness; do not drive or operate heavy machinery if you feel dizzy.

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Liver

Unsafe

Jollimine Capsule is not recommended for the liver patients.

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Kidney

Caution

Jollimine Capsule should be used with caution in patients with kidney diseases. Dose adjustments may be necessary.

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Children

Safe if prescribed

Jollimine Capsule should be used in children under the care of the doctor. The dose may depend on the weight and age of the child.

FAQs

Jollimine Capsule is used to treat severe rheumatoid arthritis, Wilsons disease, and cystinuria. Rheumatoid arthritis is a joint disorder in which our immune system attacks our body cells. Wilson disease is a genetic problem characterized by excess copper deposited in body parts like the eye, brain, and liver, leading to metal toxicity. Cystinuria is the excess build-up of an amino acid called cystine in the urinary bladder and kidney, leading to harmful effects.
Jollimine Capsule works by blocking the action of certain chemical messengers that are responsible for inflammation and prevents joint stiffness, thereby provides relief from rheumatoid arthritis.
Wilson’s disease is a condition where the body cannot get rid of copper properly and cause damage the liver, brain, and other organs. Jollimine Capsule contains penicillamine that works by helping the body to remove excess copper.
Avoid taking other medicines at the same time while taking Jollimine Capsule . If you take an iron supplement, take it at least 2 hours before or after you take Jollimine Capsule . Iron can make it harder for your body to absorb Jollimine Capsule . Avoid taking mineral supplements, unless your doctor advised you to. Do not drink milk within 1 hour before or after you take Jollimine Capsule . Do not take copper-containing foods like shellfish, chocolate, nuts, mushroom, and organ meats (liver pate, sweetbreads etc.)
Jollimine Capsule may cause side-effects such as protein in urine, low blood platelets, stomach upset or throwing up, diarrhea , change in taste, loss of appetite, mouth irritation, mouth sores. These side-effects are usually mild and temporary. However, if any of these side-effects persist or get worse, inform your doctor immediately.
Jollimine Capsule should not be taken during pregnancy or if you are trying to become pregnant as Jollimine Capsule can cause birth defects, miscarriages or harm unborn babies. Avoid becoming pregnant for at least 6 months after stopping the treatment with Jollimine Capsule .

Country of origin

India
Other Info - JOL0092

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