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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:40 PM IST
Itapro SR 400 Tablet is an antifungal medicine used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. It contains Itraconazole, which works by killing fungi. Some people may experience side effects such as nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Ajanta Pharma Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Itapro SR 400 Tablet

Itapro SR 400 Tablet is an antifungal medicine used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. Fungal infection is a disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another).

Itapro SR 400 Tablet contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, it causes the main components of fungal cells to leak out, kill fungi, and clear the fungal infection.

Take Itapro SR 400 Tablet as prescribed. Your doctor will advise you on how often you take Itapro SR 400 Tablet based on your medical condition. Some people may experience nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Most of these side effects of Itapro SR 400 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Itapro SR 400 Tablet or any other medicines, please tell your doctor. Itapro SR 400 Tablet is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy or a nursing mother, it is advised to consult a doctor before using Itapro SR 400 Tablet. Do not take Itapro SR 400 Tablet if you have or have heart failure, as it may cause severe life-threatening adverse effects. If you have kidney, liver, heart or lung problems, inform your doctor before taking Itapro SR 400 Tablet. Avoid taking fentanyl (a strong opioid narcotic medicine) with Itapro SR 400 Tablet as it may cause severe breathing problems and can even lead to death. If you experience numbness or tingling in your hands or feet, stop taking Itapro SR 400 Tablet and consult your doctor immediately as they might be symptoms of nerve damage.

Uses of Itapro SR 400 Tablet

Treatment of Fungal infections

Medicinal Benefits

Itapro SR 400 Tablet is an antifungal used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Itapro SR 400 Tablet inhibits the production of ergosterol (a main component of cell membranes of fungi). Thereby weakening and damaging the fungal cell membranes, causing the main components of fungal cells to leak out. Thus, it kills fungi and clears the fungal infection.

Directions for Use

Tablet: Take it with food to avoid stomach upset or as advised by the doctor. Swallow the whole tablet with a glass of water. Do not break, crush or chew it. If you are taking any stomach acid suppressor or have achlorhydria (stomach does not produce hydrochloric acid), take Itapro SR 400 Tablet with cola.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Itapro SR 400 Tablet

  • Nausea
  • Headache
  • Diarrhoea
  • Tiredness
  • Cough
  • Cold
  • Throat pain
  • Back pain
  • Stomach pain

Drug Warnings

If you are known to be allergic to Itapro SR 400 Tablet or any other medicines, please tell your doctor. Itapro SR 400 Tablet is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy, or are a nursing mother, it is advised to consult a doctor before using Itapro SR 400 Tablet. Avoid taking fentanyl (a strong opioid pain killer narcotic medicine) with Itapro SR 400 Tablet, as it may cause severe breathing problems and can even lead to death. Do not take Itapro SR 400 Tablet if you had heart failure as it may cause severe life-threatening adverse effects. If you experience a yellow colour change of your eyes or skin, dark coloured urine, stomach pain, pale stools, loss of appetite, unusual tiredness, vomiting or nausea, stop taking Itapro SR 400 Tablet and consult a doctor immediately as they might be symptoms of liver failure. If you have kidney, liver, heart, or lung problems, inform your doctor before taking Itapro SR 400 Tablet.

Drug Interactions

Drug-Drug Interaction: Itapro SR 400 Tablet may interact with antacids (esomeprazole, omeprazole, pantoprazole), corticosteroids (fluticasone, budesonide), opioid pain killers (hydrocodone), blood thinners (warfarin), blood cholesterol-lowering medicines (simvastatin), anti-allergic drug (terfenadine) and antianxiety drug (alprazolam).

Drug-Food Interaction: Itapro SR 400 Tablet may interact with grapefruit juice. Therefore, avoid intake of grapefruit juice with Itapro SR 400 Tablet as it may reduce the effect of Itapro SR 400 Tablet. Also, avoid intake of marijuana with Itapro SR 400 Tablet as it may worsen the adverse effects of marijuana.

Drug-Disease Interaction: Do not take Itapro SR 400 Tablet if you had heart failure as it may cause severe life-threatening adverse effects. If you have kidney, liver, heart or lung problems, inform your doctor before taking Itapro SR 400 Tablet.

Drug-Drug Interactions Checker List

  • ESOMEPRAZOLE
  • OMEPRAZOLE
  • PANTOPRAZOLE
  • FLUTICASONE
  • BUDESONIDE
  • HYDROCODONE
  • WARFARIN
  • SIMVASTATIN
  • TERFENADINE
  • ALPRAZOLAM

Habit Forming

No

Diet & Lifestyle Advise

  • Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
  • In wet places such as changing rooms and gym showers, don’t walk on barefoot to prevent fungal infections.
  • Do not scratch the affected area of skin as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bed sheets and towels regularly.

Special Advise

  • Regular blood tests are recommended before and while taking Itapro SR 400 Tablet to monitor liver functioning especially if you have any liver problems.

Disease/Condition Glossary

Fungal infection: It is a skin disease in which a fungus attacks the tissue and causes infection. It may be contagious (spread from one person to another). The symptoms of a fungal infection include blisters, itching, redness, scaling and swelling of the skin. Yeast infection is caused by a type of fungus called candida and commonly occurs in moist and warm areas of the body. It is not contagious. It may cause infections in the mouth (oral thrush), vagina, nails, groin or armpits.

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Alcohol

Unsafe

Avoid consumption of alcohol with Itapro SR 400 Tablet as it may increase the risk of liver problems and other adverse effects.

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Pregnancy

Unsafe

Itapro SR 400 Tablet is category C pregnancy drug and is unsafe for pregnant women as it may cause harm to the unborn baby. Therefore, inform your doctor if you are pregnant or planning for pregnancy before taking Itapro SR 400 Tablet.

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Breast Feeding

Caution

Itapro SR 400 Tablet is excreted in human milk and may harm the baby. Therefore, Itapro SR 400 Tablet is given to breastfeeding mothers only if doctor thinks benefits are greater than risks.

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Driving

Caution

Itapro SR 400 Tablet may cause dizziness, hearing loss, double or blurred vision in some people. Therefore, drive only if you alert after taking Itapro SR 400 Tablet.

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Liver

Caution

Take Itapro SR 400 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Itapro SR 400 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Itapro SR 400 Tablet is not recommended for children below 12 years as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India.
Other Info - ITA0025

Author Details

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FAQs

Itapro SR 400 Tablet is used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. It works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby killing fungi and clearing the fungal infection.
You are not recommended to take Itapro SR 400 Tablet with simvastatin as co-administration of these two medicines may cause muscle weakness, unexplained muscle pain or tenderness, dark coloured urine, fever or flu symptoms. However, please consult a doctor before using Itapro SR 400 Tablet with other medicines.
No, Itapro SR 400 Tablet is not recommended for use during pregnancy as it may cause harm to the fetus. Also, it is advised to use effective contraceptive measures while taking Itapro SR 400 Tablet and after 2 months of stopping treatment with Itapro SR 400 Tablet. However, please inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before taking Itapro SR 400 Tablet.
Itapro SR 400 Tablet may cause temporary or permanent hearing loss in some people. It is not necessary for everyone taking Itapro SR 400 Tablet to experience this adverse effect. However, if you notice any changes in hearing, stop taking Itapro SR 400 Tablet and consult a doctor immediately.
You are advised to take antacids (drugs used to reduce acid in the stomach) such as omeprazole, pantoprazole and esomeprazole at least 1 hour before or 2 hours after taking Itapro SR 400 Tablet as co-administration of these medicines at the same time may reduce the effectiveness of Itapro SR 400 Tablet because antacids decrease the absorption and blood levels of Itapro SR 400 Tablet. However, please consult a doctor before taking other medicines with Itapro SR 400 Tablet.
Yes, fungal infection is a contagious skin condition which spreads from one person to another through direct skin to skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person as it can also spread the infection.
You are not recommended to stop taking Itapro SR 400 Tablet without consulting your doctor as it may cause recurring infection. Therefore, take Itapro SR 400 Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Itapro SR 400 Tablet, please consult your doctor.
Inform your doctor if you are sexually active and discuss effective contraception methods. Itapro SR 400 Tablet may reduce the effectiveness of oral contraceptive pills. Thus, you are advised to use barrier methods of contraception like condoms, if you are taking Itapro SR 400 Tablet.
Inform the doctor about your detailed medical and surgical history, if you have liver, kidney or heart disease or fits and if you are pregnant, breastfeeding or planning pregnancy. Inform your doctor if you are taking any other medicines including supplements or herbal products as Itapro SR 400 Tablet may interact with other medicines. Also, let your doctor know if you are stopping any medicine.
Itapro SR 400 Tablet contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, it causes the main components of fungal cells to leak out, kill fungi, and clear the fungal infection.
Yes, you should swallow the capsule whole with a glass of water. Do not crush, chew or break it.
The side effects of Itapro SR 400 Tablet include nausea, headache, diarrhoea, stomach pain, fatigue (overtiredness), back pain, cough, and sore throat. If these side effects persist or worsen, please consult your doctor.
If you have taken overdose of Itapro SR 400 Tablet, please consult your doctor immediately.
Store Itapro SR 400 Tablet at room temperature. Protect from light and moisture. Keep out of reach and sight of children.

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