It-Mac 400mg Tablet is an antifungal medicine used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. Fungal infection is a disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another).

It-Mac 400mg Tablet contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, it causes the main components of fungal cells to leak out, kill fungi, and clear the fungal infection.

Take It-Mac 400mg Tablet as prescribed. Your doctor will advise you on how often you take It-Mac 400mg Tablet based on your medical condition. Some people may experience nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Most of these side effects of It-Mac 400mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to It-Mac 400mg Tablet or any other medicines, please tell your doctor. It-Mac 400mg Tablet is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy or a nursing mother, it is advised to consult a doctor before using It-Mac 400mg Tablet. Do not take It-Mac 400mg Tablet if you have or have heart failure, as it may cause severe life-threatening adverse effects. If you have kidney, liver, heart or lung problems, inform your doctor before taking It-Mac 400mg Tablet. Avoid taking fentanyl (a strong opioid narcotic medicine) with It-Mac 400mg Tablet as it may cause severe breathing problems and can even lead to death. If you experience numbness or tingling in your hands or feet, stop taking It-Mac 400mg Tablet and consult your doctor immediately as they might be symptoms of nerve damage.

It-Mac 400mg Tablet is an antifungal used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. It-Mac 400mg Tablet inhibits the production of ergosterol (a main component of cell membranes of fungi). Thereby weakening and damaging the fungal cell membranes, causing the main components of fungal cells to leak out. Thus, it kills fungi and clears the fungal infection.

• Nausea
• Headache
• Diarrhoea
• Tiredness
• Cough
• Cold
• Throat pain
• Back pain
• Stomach pain

If you are known to be allergic to It-Mac 400mg Tablet or any other medicines, please tell your doctor. It-Mac 400mg Tablet is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy, or are a nursing mother, it is advised to consult a doctor before using It-Mac 400mg Tablet. Avoid taking fentanyl (a strong opioid pain killer narcotic medicine) with It-Mac 400mg Tablet, as it may cause severe breathing problems and can even lead to death. Do not take It-Mac 400mg Tablet if you had heart failure as it may cause severe life-threatening adverse effects. If you experience a yellow colour change of your eyes or skin, dark coloured urine, stomach pain, pale stools, loss of appetite, unusual tiredness, vomiting or nausea, stop taking It-Mac 400mg Tablet and consult a doctor immediately as they might be symptoms of liver failure. If you have kidney, liver, heart, or lung problems, inform your doctor before taking It-Mac 400mg Tablet.

Drug-Drug Interaction: It-Mac 400mg Tablet may interact with antacids (esomeprazole, omeprazole, pantoprazole), corticosteroids (fluticasone, budesonide), opioid pain killers (hydrocodone), blood thinners (warfarin), blood cholesterol-lowering medicines (simvastatin), anti-allergic drug (terfenadine) and antianxiety drug (alprazolam).

Drug-Food Interaction: It-Mac 400mg Tablet may interact with grapefruit juice. Therefore, avoid intake of grapefruit juice with It-Mac 400mg Tablet as it may reduce the effect of It-Mac 400mg Tablet. Also, avoid intake of marijuana with It-Mac 400mg Tablet as it may worsen the adverse effects of marijuana.

Drug-Disease Interaction: Do not take It-Mac 400mg Tablet if you had heart failure as it may cause severe life-threatening adverse effects. If you have kidney, liver, heart or lung problems, inform your doctor before taking It-Mac 400mg Tablet.

• ESOMEPRAZOLE
• OMEPRAZOLE
• PANTOPRAZOLE
• FLUTICASONE
• BUDESONIDE
• HYDROCODONE
• WARFARIN
• SIMVASTATIN
• TERFENADINE
• ALPRAZOLAM

• Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
• In wet places such as changing rooms and gym showers, don’t walk on barefoot to prevent fungal infections.
• Do not scratch the affected area of skin as it can spread the infection to other body parts.
• Avoid sharing towels, combs, bedsheets, shoes or socks with others.
• Wash your bed sheets and towels regularly.

• Regular blood tests are recommended before and while taking It-Mac 400mg Tablet to monitor liver functioning especially if you have any liver problems.

Fungal infection: It is a skin disease in which a fungus attacks the tissue and causes infection. It may be contagious (spread from one person to another). The symptoms of a fungal infection include blisters, itching, redness, scaling and swelling of the skin. Yeast infection is caused by a type of fungus called candida and commonly occurs in moist and warm areas of the body. It is not contagious. It may cause infections in the mouth (oral thrush), vagina, nails, groin or armpits.