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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Ismotag 5mg Tablet is used in the prevention of angina (heart-related chest pain) or heart failure. It contains Isosorbide dinitrate, which works by dilating, relaxing, and widening the constricted blood vessels, thereby increasing the blood and oxygen supply to the heart. Thus, it effectively helps prevent the risk of future heart attack and stroke in the future, especially in high blood pressure patients. It may cause common side effects such as headache (during initial days of therapy) and flushing (reddening of the skin, especially the face). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Innovative Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Ismotag 5mg Tablet

Ismotag 5mg Tablet belongs to the class of blood pressure-lowering medications called ‘nitrate vasodilators’ used in the prevention of angina (heart-related chest pain) or heart failure. Angina pectoris (angina) is chest pain occurring due to reduced blood flow to the heart (coronary artery disease). It occurs when the blood vessels supplying the heart are blocked or narrowed.

Ismotag 5mg Tablet contains ‘isosorbide dinitrate’, which works by dilating, relaxing, and widening the constricted blood vessels, thereby increasing the blood and oxygen supply to the heart. Thus, it effectively helps prevent the risk of future heart attack and stroke in the future, especially in high blood pressure patients. 

Take Ismotag 5mg Tablet as prescribed. Your doctor will advise you on how often you take Ismotag 5mg Tablet based on your medical condition. The common side-effects of Ismotag 5mg Tablet are headache (during initial days of therapy) and flushing (reddening of the skin, especially the face). These side effects usually disappear without requiring medical attention. However, consult your doctor immediately if these effects persist or worsen.

Do not take it if you are allergic to ‘isosorbide dinitrate’ or any of its ingredients. Do not use in patients with severe heart failure, severe hypotension (low blood pressure), bleeding in the brain, severe dehydration, heart valve problems, progressive heart failure due to chronic lung disease, severe anemia (low levels of iron), and severe hypoxemia (low levels of oxygen in the blood). Inform your doctor if you have an underactive thyroid gland, glaucoma (an eye condition), or head injury. Inform your doctor if you are taking other prescription or non-prescription medicines, especially medicines used to treat erectile dysfunction in men. Ismotag 5mg Tablet contains lactose, so inform your doctor if you have an intolerance to some sugars. Also, inform your doctor if you are pregnant or breastfeeding.

Uses of Ismotag 5mg Tablet

Treatment of angina (heart-related chest pain)

Directions for Use

Oral: Swallow it as a whole with a glass of water. Do not crush, break or chew it.Sublingual: Place the tablet under the tongue and allow it to dissolve.

Medicinal Benefits

Ismotag 5mg Tablet contains ‘isosorbide dinitrate’, which is a ‘nitrate’ and a vasodilator. It acts by dilating and relaxing the constricted blood vessels due to increased blood pressure (hypertension). This effect helps in improving the blood and oxygen supply to the heart, thus decreasing the risk of angina or heart-related chest pain. Thus, Ismotag 5mg Tablet prevents the risk of chest pain in heart conditions like coronary artery disease.

How Ismotag 5mg Tablet Works

Ismotag 5mg Tablet contains ‘isosorbide dinitrate’, which works by dilating, relaxing, and widening the constricted blood vessels, thereby increasing the blood and oxygen supply to the heart. Thus, it effectively helps prevent the risk of future heart attack and stroke in the future, especially in high blood pressure patients.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ismotag 5mg Tablet

  • Headache
  • Flushing (redness of the skin, especially the face)
  • Low blood pressure
  • Dizziness

What if I have taken an overdose of Ismotag 5mg Tablet

Do not take more than the prescribed dose of Ismotag 5mg Tablet as it may cause overdose. The symptoms of overdose include fever, confusion, severe throbbing headache, fast or pounding heartbeats, severe dizziness, nausea, vomiting, stomach pain, vision problems, bloody diarrhoea, stomach pain, sweating, trouble breathing, fainting, cold or clammy skin, and seizures (fits). If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Ismotag 5mg Tablet if you are allergic to ‘isosorbide dinitrate’ or its contents. Do not take it if you have severe low blood pressure, bleeding or increased pressure in the brain, severe dehydration, heart valve problems, inflammation of the heart wall, high blood pressure due to long-term lung disease, and severe anemia. Before taking Ismotag 5mg Tablet, inform your doctor if you have glaucoma (increased pressure in the eye), glucose 6 phosphate dehydrogenase deficiency (a type of anemia), underactive thyroid (hypothyroidism), kidney or liver problems, head injury, hypothermia (low body temperature), or intolerance to some sugars. This medicine should not be used with medicines used for erectile dysfunction like sildenafil or tadalafil. Inform your doctor if you are pregnant or breastfeeding.

Drug-Drug Interactions

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Isosorbide dinitrateAvanafil
Critical
Isosorbide dinitrateSildenafil
Critical

Drug-Drug Interactions

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Isosorbide dinitrateAvanafil
Critical
How does the drug interact with Ismotag 5mg Tablet:
Taking Avanafil with Ismotag 5mg Tablet can cause low blood pressure.

How to manage the interaction:
Taking Ismotag 5mg Tablet with Avanafil is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, priapism in males (persistent and painful erection unrelated to sexual activity). Do not discontinue any medications without consulting a doctor.
Isosorbide dinitrateSildenafil
Critical
How does the drug interact with Ismotag 5mg Tablet:
Coadministration of Ismotag 5mg Tablet and Sildenafil can increase the risk of low blood pressure.

How to manage the interaction:
Taking Ismotag 5mg Tablet and Sildenafil together is generally avoided as it can lead to an interaction, it can be taken only if advised by your doctor. However, if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity) contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Isosorbide dinitrateTadalafil
Critical
How does the drug interact with Ismotag 5mg Tablet:
Taking Tadalafil with Ismotag 5mg Tablet can increase the risk or severity of low blood pressure.

How to manage the interaction:
Taking Ismotag 5mg Tablet with Tadalafil is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Isosorbide dinitrateRiociguat
Critical
How does the drug interact with Ismotag 5mg Tablet:
Taking Riociguat with Ismotag 5mg Tablet may lead to excessively low blood pressure.

How to manage the interaction:
Taking Ismotag 5mg Tablet with Riociguat is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, priapism in males (persistent and painful erection unrelated to sexual activity). Do not discontinue any medications without consulting a doctor.
Isosorbide dinitrateSodium nitrite
Severe
How does the drug interact with Ismotag 5mg Tablet:
Taking Ismotag 5mg Tablet with sodium nitrite may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Ismotag 5mg Tablet and sodium nitrite together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Isosorbide dinitrateCabergoline
Severe
How does the drug interact with Ismotag 5mg Tablet:
Coadministration of Ismotag 5mg Tablet and cabergoline may decrease your blood pressure.

How to manage the interaction:
Co-administration of Ismotag 5mg Tablet with Cabergoline can result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these signs - headache, dizziness, feeling lightheaded, or fainting, contact your doctor immediately. Do not stop using any medications without talking to your doctor.
Isosorbide dinitrateRopivacaine
Severe
How does the drug interact with Ismotag 5mg Tablet:
Taking Ismotag 5mg Tablet with ropivacaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Ismotag 5mg Tablet and ropivacaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Isosorbide dinitrateLidocaine
Severe
How does the drug interact with Ismotag 5mg Tablet:
Taking Ismotag 5mg Tablet with lidocaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Ismotag 5mg Tablet and lidocaine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Isosorbide dinitrateCabergoline
Severe
How does the drug interact with Ismotag 5mg Tablet:
Taking Ismotag 5mg Tablet with cabergoline can increase the effects of Cabergoline.

How to manage the interaction:
Although taking Ismotag 5mg Tablet and cabergoline together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. Do not stop using any medications without consulting doctor.
Isosorbide dinitrateBupivacaine
Severe
How does the drug interact with Ismotag 5mg Tablet:
Combining Bupivacaine with Ismotag 5mg Tablet can increase the risk of methemoglobinemia(a rare condition that can lead to oxygen deprivation in tissues and vital organs due to reduced oxygen-carrying capacity of the blood).

How to manage the interaction:
Co-administration of Bupivacaine with Ismotag 5mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, confusion, consult a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat plenty of fresh fruits and vegetables. Choose whole grains rather than refined or polished grains. Choose lean proteins, such as skinless chicken and fish. Choose non-fat or low-fat dairy products.
  • Do not take food containing high levels of sodium (salt).
  • Drink plenty of fluids to prevent dehydration. 
  • Maintain a normal weight. Shed excess weight by exercising regularly for at least 30 min a day.
  • Manage stress.
  • Limit alcohol intake and quit smoking.

Habit Forming

No

Therapeutic Class

ANTIANGINALS

Ismotag 5mg Tablet Substitute

Substitutes safety advice
  • Sorbitrate 5 mg Tablet 50's

    by Others

    0.82per tablet
  • Isordil 5 Sublingual Tablet 10's

    by Others

    0.81per tablet
  • Isordril-5 Tablet 10's

    by Others

    0.90per tablet
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Alcohol

Caution

Alcohol may worsen the condition by increasing the risk of side-effects. So, do not consume alcohol.

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Pregnancy

Caution

Ismotag 5mg Tablet is a category C medicine and may cause harm to the fetus. It should be used in pregnant women if clinically needed and when benefits outweigh the risks.

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Breast Feeding

Caution

Ismotag 5mg Tablet should be used with caution in breastfeeding mothers.

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Driving

Caution

Ismotag 5mg Tablet may cause dizziness and affect your ability to drive. So, avoid driving or operating heavy machinery while using Ismotag 5mg Tablet.

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Liver

Caution

Ismotag 5mg Tablet should be used with caution in patients with liver diseases. Dose adjustments may be required in severe liver disease patient.

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Kidney

Caution

Ismotag 5mg Tablet should be used with caution in patients with kidney diseases. Dose adjustments may be required.

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Children

Caution

$should not be used in children unless clinically needed. Dose adjustments may be necessary.

FAQs

Ismotag 5mg Tablet is used to prevent angina (heart-related chest pain) or heart failure.
Ismotag 5mg Tablet is a 'vasodilator' and can prevent angina effectively. It works by relaxing the muscles of blood vessels. It helps to dilate the narrowed blood vessels resulting in increased blood and oxygen supply to the heart. This prevents heart-related chest pain known as angina.
Ismotag 5mg Tablet is used to prevent angina attacks. However, it cannot stop the angina attack that has already started as it works very slowly (delayed onset of action).
Ismotag 5mg Tablet may decrease blood pressure (hypotension). So it should not be used in patients with severe hypotension.
Lisinopril is a medication used to treat high blood pressure. Using Ismotag 5mg Tablet with lisinopril may cause a decrease in blood pressure (hypotension). So, consult your doctor before taking other medications while using Ismotag 5mg Tablet.
Use of Ismotag 5mg Tablet together with sildenafil is not recommended as it may cause a sudden decrease in blood pressure leading to loss of consciousness, even leading to coma stage.
Ismotag 5mg Tablet is given for heart-related chest pain (angina), a life-long or chronic disease, especially in high blood pressure patients and coronary heart disease (CAD). So, do not stop taking Ismotag 5mg Tablet even if you feel better. It would be best if you took Ismotag 5mg Tablet until your doctor tells you to stop.
Ismotag 5mg Tablet is sometimes used only when needed, you may not be on a dosing schedule. If you are on a schedule, take the missed dose as soon as you remember or if it's nearly time for your next dose, skip your missed dose. Do not use extra medicine to make up a missed dose.

Manufacturer/Marketer address

SCO 133, SEC 14, PANCHKULA, HARYANA, 134113, 7626908999
Other Info - IS25907

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