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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Isac-20 Capsule is used to treat a severe form of acne known as nodular acne that cannot be cleared by any other treatments, including antibiotics. It contains Isotretinoin, a form of vitamin A, which works by reducing sebum (skin's natural oil) production on the skin's surface by decreasing the activity and size of sebaceous glands. Thereby, unblocks pores and kills acne-causing bacteria. Some people may experience chapped lips, dryness of skin, eyes, nose, or lips. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Composition :

ISOTRETINOIN-20MG

Manufacturer/Marketer :

Systopic Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

Isac-20 Capsule belongs to a class of drugs called retinoids (a synthetic form of vitamin A) primarily used to treat a severe form of acne known as nodular acne that cannot be cleared by any other treatments, including antibiotics. Nodular acne is severe acne that occurs due to excessive production of oil in the skin cells, causing swollen, red and tender lumps in the skin. Acne nodules are larger in size than typical pimples. 

Isac-20 Capsule contains 'isotretinoin', a form of vitamin A that works by reducing sebum (skin's natural oil) production on the skin's surface by decreasing the activity and size of sebaceous glands. Thereby unblocks pores and kills acne-causing bacteria.

Take Isac-20 Capsule as prescribed. Your doctor will advise you on how often you need to take Isac-20 Capsule based on your medical condition. Some people may experience chapped lips, dryness of skin, eyes, nose, or lips. Most of these side effects of Isac-20 Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Isac-20 Capsule or any other medicines, please tell your doctor. Do not take Isac-20 Capsule if you are pregnant or breastfeeding as it may cause adverse effects on the baby. If you have depression or any suicidal thoughts while taking Isac-20 Capsule or after stopping treatment with Isac-20 Capsule , please consult a doctor. Avoid sun exposure while using Isac-20 Capsule as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn.

Treatment of Nodular acne
Take Isac-20 Capsule with food or as advised by the doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Isac-20 Capsule is a synthetic form of vitamin A used to treat a severe form of acne. Isac-20 Capsule reduces sebum (skin's natural oil) production on the skin's surface by decreasing the activity and size of sebaceous glands. Thereby unblocking pores and killing acne-causing bacteria. Also, Isac-20 Capsule reduces swelling in the skin.

Isac-20 Capsule contains 'isotretinoin', a form of vitamin A that works by reducing sebum (skin's natural oil) production on the skin's surface by decreasing the activity and size of sebaceous glands. Thereby unblocks pores and kills acne-causing bacteria.
Store in a cool and dry place away from sunlight
  • Chapped lips

  • Dryness of skin, eyes, nose or lips
Do not take more than the prescribed dose of Isac-20 Capsule as it may cause overdose. The symptoms of overdose include vomiting, dizziness, headache, stomach pain, loss of balance or coordination, warmth or tingling in your face and swollen or cracked lips. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Do not take Isac-20 Capsule if you are pregnant or breastfeeding as it may cause adverse effects in the baby. If you have depression or any suicidal thoughts while taking Isac-20 Capsule or after stopping treatment with Isac-20 Capsule , please consult a doctor. Avoid sun exposure while using Isac-20 Capsule as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. Do not undergo any cosmetic procedures while taking Isac-20 Capsule and for a minimum of 6 months after stopping treatment with Isac-20 Capsule as it may increase the risk of scarring. Inform your doctor if you have asthma, diabetes, hypervitaminosis A (high levels of vitamin A), liver or heart problems, weak bones, osteoporosis (bone loss), anorexia nervosa (an eating disorder where people eat too little), any mental problems such as psychosis (loss of contact with reality) or depression before taking Isac-20 Capsule .

verifiedApollotooltip
IsotretinoinDoxycycline
Critical
IsotretinoinOxytetracycline
Critical

Drug-Drug Interactions

IsotretinoinDoxycycline
Critical
How does the drug interact with Isac-20 Capsule 10's:
Taking Isac-20 Capsule 10's with Doxycycline may increase the risk of a rare condition called pseudotumor cerebri (increased pressure in the brain).

How to manage the interaction:
Although taking Isac-20 Capsule 10's and Doxycycline together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, nausea, vomiting, and visual disturbances, consult a doctor. Do not stop using any medications without consulting doctor.
IsotretinoinOxytetracycline
Critical
How does the drug interact with Isac-20 Capsule 10's:
Co-administration of Isac-20 Capsule 10's with Oxytetracycline can increase the risk of pseudotumor cerebri (caused by increased pressure in the brain).

How to manage the interaction:
Taking Isac-20 Capsule 10's and Oxytetracycline together is not recommended as it can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, nausea, vomiting, and visual disturbances, consult a doctor. Do not stop using any medications without consulting doctor.
IsotretinoinDemeclocycline
Critical
How does the drug interact with Isac-20 Capsule 10's:
Taking Isac-20 Capsule 10's with Demeclocycline may increase the risk of a rare and serious condition called pseudotumor cerebri (increased pressure in the brain).

How to manage the interaction:
Although taking Isac-20 Capsule 10's and Demeclocycline together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, nausea, vomiting, and visual disturbances, consult a doctor. Do not stop using any medications without consulting doctor.
IsotretinoinAminolevulinic acid
Severe
How does the drug interact with Isac-20 Capsule 10's:
Taking Isac-20 Capsule 10's with aminolevulinic acid may increase the risk of a severe sunburn.

How to manage the interaction:
Although taking Isac-20 Capsule 10's and aminolevulinic acid together can possibly result in an interaction, it can be taken if your doctor has prescribed it. After taking you should avoid exposure of the eyes and skin to sunlight or bright indoor lights for 48 hours. Incase you experience any unusual symptoms, consult a doctor. Do not stop using any medications without consulting doctor.
IsotretinoinTretinoin
Severe
How does the drug interact with Isac-20 Capsule 10's:
Taking Isac-20 Capsule 10's together with tretinoin may increase the risk of hypervitaminosis A (excessive vitamin A-related effects).

How to manage the interaction:
Although taking Isac-20 Capsule 10's and tretinoin together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as increased pressure in the brain (headache, nausea, vomiting, visual disturbances) or liver damage (fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, yellowing of the skin or eyes). Do not stop using any medications without consulting doctor.
IsotretinoinTeriflunomide
Severe
How does the drug interact with Isac-20 Capsule 10's:
Taking Isac-20 Capsule 10's with teriflunomide may affect liver and causes liver problems.

How to manage the interaction:
Although taking Isac-20 Capsule 10's and teriflunomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, light-coloured stools, and/or yellowing of the skin or eyes. Do not stop using any medications without consulting doctor.
IsotretinoinLomitapide
Severe
How does the drug interact with Isac-20 Capsule 10's:
Taking Isac-20 Capsule 10's with lomitapide may affect liver and cause liver problems.

How to manage the interaction:
Although taking Isac-20 Capsule 10's and lomitapide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
IsotretinoinMinocycline
Severe
How does the drug interact with Isac-20 Capsule 10's:
Taking Isac-20 Capsule 10's with minocycline may increase the risk of a rare and serious condition called pseudotumor cerebri (increased pressure in the brain).

How to manage the interaction:
Although taking Isac-20 Capsule 10's and minocycline together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, nausea, vomiting, and visual disturbances, consult a doctor. Do not stop using any medications without consulting a doctor.
verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

  • Regular exercise can improve your mood and self-esteem though it doesn't clear acne. Take a shower immediately after finishing exercise as sweat may irritate acne.

  • Avoid sun exposure while using Isac-20 Capsule as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn.

  • Do regular hair wash and avoid contact of hair with the face.

  • Remove the make-up completely before going to bed.

No
RETINOIDS

Isac-20 Capsule Substitute

Substitutes safety advice
  • Isotroin-20 Softgel Capsule 15's

    by AYUR

    29.54per tablet
  • Sotret 20 mg Capsule 10's

    31.77per tablet
  • Acutret 20 Capsule 10's

    27.18per tablet
  • Tretiva-20 Capsule 10's

    23.40per tablet
  • Tretin-Iso 20 Capsule 10's

    27.90per tablet
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FAQs

Isac-20 Capsule is used to treat a severe form of acne known as nodular acne that cannot be cleared by any other treatments, including antibiotics.
Isac-20 Capsule may cause decreased night vision temporarily or permanently in some patients. It is not necessary for everyone taking Isac-20 Capsule to experience this side effect. Avoid driving after taking Isac-20 Capsule if you are unable to see in the dark and consult a doctor if you notice any changes in vision or have painful or persistent dry eyes.
Isac-20 Capsule may increase the skin sensitivity to sunlight. Therefore, avoid or limit exposure to sunlight and sunlamps. You are advised to use sunscreen and wear protective clothing while going out to prevent sunburn.
No, you are not recommended to undergo any cosmetic procedures to smoothen your skin including waxing, laser procedures or dermabrasion (an exfoliating technique to remove outer layers of skin with a rotating instrument) while taking Isac-20 Capsule and for minimum 6 months after stopping treatment with Isac-20 Capsule as it may increase the risk of scarring.
You are not recommended to take vitamin A supplements with Isac-20 Capsule as it may cause hypervitaminosis A (excessive levels of vitamin A in the body) leading to an increased risk of adverse effects. However, please consult a doctor before taking other medicines or supplements with Isac-20 Capsule .
No, Isac-20 Capsule is not recommended for use during pregnancy as it may cause severe birth defects. Also, it is advised to use effective contraceptive measures before, while taking Isac-20 Capsule and after 1 month of stopping treatment with Isac-20 Capsule . However, please inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before taking Isac-20 Capsule .
Isac-20 Capsule is safe to use if prescribed by the doctor. Use Isac-20 Capsule exactly as advised by the doctor as it is associated with adverse effects.
Isac-20 Capsule is not a steroid. It is a retinoid used to treat severe nodular acne.
Pregnancy tests, lipid profile tests, liver function tests, blood glucose tests, and creatine phosphokinase (CPK) tests are recommended tests during Isac-20 Capsule treatment.
In most cases the effect of Isac-20 Capsule is permanent. Isotretinoin is clinically effective anti-acne therapy that shows significant improvement in many patients.
Isac-20 Capsule does not cause cancer. In fact, isotretinoin slows the growth of cancer cells by activating protein receptors in cells, including cancer cells.
Long-term use of Isac-20 Capsule , even in low doses, has not been studied and is not recommended. Hence, long-term side effects of Isac-20 Capsule have not been established.
Isac-20 Capsule is not known to affect male fertility.
Isac-20 Capsule might elevate liver enzymes. Therefore, regular liver function tests are advised.
Side effects of Isac-20 Capsule include chapped lips and dry skin, eyes, nose, or lips. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
India
Systopic Laboratories Pvt. Ltd., 101, Pragati Chambers, Commercial Complex, Ranjit Nagar, New Delhi-110008
Other Info - ISA0003

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