Insed Plus Atomise Nasal Spray 2.5 ml belongs to a class of drugs called benzodiazepines (sedatives) used to induce sedation and relieve anxiety and muscle tension. It is used to induce sleepiness during therapeutic procedures (like endoscopy or colonoscopy) or complicated medical tests known as procedural sedation. Conscious sedation is a technique in which drugs help you relax (sedative), reduce anxiety and inhibit pain (anaesthetic) during a medical test or procedure. It is usually referred to as procedural sedation and analgesia.

Insed Plus Atomise Nasal Spray 2.5 ml contains Midazolam which works by increasing GABA activity (a chemical messenger in the brain that acts as a natural nerve-calming agent) involved in inducing drowsiness. Thereby, Insed Plus Atomise Nasal Spray 2.5 ml relaxes muscles, reduces anxiety and causes drowsiness.

Insed Plus Atomise Nasal Spray 2.5 ml will be administered by a healthcare professional; do not self-administer. Sometimes, it may cause side effects such as redness, pain or swelling at the injection site, headache, drowsiness, dizziness, confusion, dry mouth, tiredness or muscle spasms. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Midazolam or any other medicines, please tell your doctor. If you are pregnant or planning pregnancy, inform your doctor before taking Insed Plus Atomise Nasal Spray 2.5 ml. It may be excreted in breast milk. Therefore, avoid breastfeeding for 24 hours after taking Insed Plus Atomise Nasal Spray 2.5 ml. Insed Plus Atomise Nasal Spray 2.5 ml should be used with caution in elderly patients as there is an increased risk of breaking bones and falling. Special care should be taken while treating children with Insed Plus Atomise Nasal Spray 2.5 ml. Avoid consumption of alcohol while on treatment with Insed Plus Atomise Nasal Spray 2.5 ml as it may increase the sedative effect. Insed Plus Atomise Nasal Spray 2.5 ml may cause drowsiness or affect concentration and coordination. It is an offence to drive if Insed Plus Atomise Nasal Spray 2.5 ml affects you. Therefore, avoid driving if you feel drowsy after taking Insed Plus Atomise Nasal Spray 2.5 ml.

Insed Plus Atomise Nasal Spray 2.5 ml contains Midazolam used to induce conscious sedation (awake but very relaxed state of calm or drowsiness) during therapeutic procedures or medical tests. Insed Plus Atomise Nasal Spray 2.5 ml increases the activity of GABA (a chemical messenger in the brain that acts as a natural nerve-calming agent) that is involved in inducing drowsiness. Thereby, Insed Plus Atomise Nasal Spray 2.5 ml relaxes muscles, reduces anxiety and causes drowsiness.

• Redness, pain or swelling at the injection site
• Headache
• Drowsiness
• Dizziness
• Confusion
• Dry mouth
• Tiredness
• Muscle spasms

If you are allergic to Midazolam or any other medicines, please inform your doctor. If you are pregnant or planning pregnancy, inform your doctor before taking Insed Plus Atomise Nasal Spray 2.5 ml. Insed Plus Atomise Nasal Spray 2.5 ml may be excreted in breast milk. Therefore, avoid breastfeeding for 24 hours after taking Insed Plus Atomise Nasal Spray 2.5 ml. Insed Plus Atomise Nasal Spray 2.5 ml should be used with caution in elderly patients as there is an increased risk of breaking bones and falling. Special care should be taken while giving Insed Plus Atomise Nasal Spray 2.5 ml to children, and the dose should be adjusted appropriately. Avoid consumption of alcohol with Insed Plus Atomise Nasal Spray 2.5 ml as it may increase the sedative effect of Insed Plus Atomise Nasal Spray 2.5 ml. Insed Plus Atomise Nasal Spray 2.5 ml may cause drowsiness or affect concentration and coordination. It is an offence to drive if Insed Plus Atomise Nasal Spray 2.5 ml affects you. Therefore, avoid driving if you feel drowsy after taking Insed Plus Atomise Nasal Spray 2.5 ml. Do not take Insed Plus Atomise Nasal Spray 2.5 ml with opioids as it may increase the risk of difficulties in breathing, drowsiness or coma. However, if the concomitant use is advised by a doctor, the dose and duration should be limited by a doctor.

Drug-Drug Interaction: Inform your doctor if you are taking high blood pressure-lowering medicines (diltiazem, nifedipine, verapamil), antifungals (fluconazole, ketoconazole, voriconazole, itraconazole, posaconazole), antibiotics (clarithromycin, erythromycin, roxithromycin, rifampicin), high cholesterol-lowering medicines (atorvastatin), medicines for HIV/AIDS (saquinavir), anticonvulsants (phenytoin, carbamazepine), opioid pain killers (fentanyl), anti-allergic medicines, antianxiety drug (diazepam), antidepressants, and other medicines.

Drug-Food Interaction: Insed Plus Atomise Nasal Spray 2.5 ml may interact with grapefruit. Therefore, avoid intake of grapefruit or grapefruit juice with Insed Plus Atomise Nasal Spray 2.5 ml as it may increase the adverse effects of Insed Plus Atomise Nasal Spray 2.5 ml. Also, avoid alcohol consumption with Insed Plus Atomise Nasal Spray 2.5 ml as it may increase the sedative effect. Inform your doctor if you are taking St. John's wort (a herbal medicine).

Drug-Disease Interaction: If you have a lung or breathing disorder, myasthenia gravis (muscle weakness), history of drug abuse or personality disorder, or kidney, liver or heart problems, inform your doctor before taking Insed Plus Atomise Nasal Spray 2.5 ml.

• DILTIAZEM
• NIFEDIPINE
• VERAPAMIL
• FLUCONAZOLE
• KETOCONAZOLE
• VORICONAZOLE
• ITRACONAZOLE
• POSACONAZOLE
• CLARITHROMYCIN
• ERYTHROMYCIN
• ROXITHROMYCIN
• RIFAMPICIN
• ATORVASTATIN
• SAQUINAVIR
• PHENYTOIN
• CARBAMAZEPINE
• FENTANYL
• DIAZEPAM

If you receive Insed Plus Atomise Nasal Spray 2.5 ml for prolonged periods, it may cause dependence and withdrawal symptoms. Therefore, do not stop taking Insed Plus Atomise Nasal Spray 2.5 ml suddenly. Your doctor will reduce the dose gradually to avoid withdrawal symptoms.

Conscious sedation: It is a technique in which drugs help you relax (sedative), reduce anxiety and inhibit pain (anaesthetic) during a medical test or procedure. You will stay awake but may not be able to speak. It is usually referred to as procedural sedation and analgesia.