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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Infimab Injection is used in the treatment of Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis, Plaque psoriasis, Crohn's disease and Ulcerative colitis. It consists of Infliximab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain caused by various autoimmune diseases.

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Composition :

INFLIXIMAB-100MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Infimab Injection

Infimab Injection belongs to the class of monoclonal TNF (Tumor necrosis factor) inhibitors that help reduce signs and symptoms of autoimmune disorders. It is primarily used in the treatment of rheumatoid arthritis, ankylosing spondylitis, juvenile idiopathic arthritis, plaque psoriasis, and psoriatic arthritis. This medicine is also used in the treatment of Crohn’s disease, ulcerative colitis, hidradenitis suppurativa, and uveitis.

Infimab Injection consists of Infliximab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain caused by various autoimmune diseases.

Infimab Injection may cause certain side effects such as nausea, headache, back pain, upper respiratory tract infections, vision problems, dizziness, pale skin, numbness, chest pain, rash, and injection site reactions. Most of these side effects do not require medical attention or resolve over time. However, if these side effects persist for longer, please consult your doctor on priority. Infimab Injection is a parenteral medicine. It will be administered by a trained healthcare doctor. Hence, do not self-administer. 

Infimab Injection may not be suitable for all. Inform your doctor if you are allergic to any of its components. Tell your doctor if you have any history of serious infections, tuberculosis, optimistic infections, cancer, hepatitis B virus infection, heart failure, liver, heart, or kidney diseases, or a weak immune system before taking Infimab Injection, as it can worsen your condition. Infimab Injection may cause dizziness, so drive only if you are alert and focused. Infimab Injection should not be given to children under two years of age as safety has not been established. Inform the doctor if you are pregnant or breastfeeding beforehand.

Uses of Infimab Injection

Infimab Injection is used in the treatment of Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis, Plaque psoriasis, Crohn's disease and Ulcerative colitis

Directions for Use

Infimab Injection will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

Infimab Injection consists of Infliximab, which belongs to the class of monoclonal TNF (Tumor necrosis factor) inhibitors. Infimab Injection works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain, redness, and inflammation (swelling) caused by various autoimmune diseases.

How Infimab Injection Works

Infimab Injection consists of Infliximab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain caused by various autoimmune diseases.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Infimab Injection

  • Headache
  • Cough
  • Stomach pain
  • Fever
  • Rash
  • Itching
  • Chills
  • Chest pain
  • Shortness of breath

What if I have taken an overdose of Infimab Injection

Since Infimab Injection is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

Infimab Injection should be avoided if allergic to it or any other components present. Inform your doctor if you have any history of serious infections, tuberculosis, optimistic infections, hepatitis B virus infection, heart failure, liver, heart or kidney diseases, weak immune system, multiple sclerosis (nerve and muscle disease), or diabetes while taking this medicine, as it can worsen these conditions. Lymphomas and other malignancies were reported in children and adolescents treated with Infimab Injection. Hence, it should be used with caution. Do not take live vaccines while being treated with Infimab Injection to prevent any serious consequences. Infimab Injection is not recommended for use in children below six years of age as safety and efficacy are not established. This medicine is not recommended for patients suffering from sepsis as it can worsen the condition.

Drug-Drug Interactions

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InfliximabFingolimod
Severe
InfliximabMercaptopurine
Severe

Drug-Drug Interactions

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InfliximabFingolimod
Severe
How does the drug interact with Infimab Injection 1's:
taking Infimab Injection 1's and Fingolimod together can increase the risk or severity of developing serious infections.

How to manage the interaction:
Although taking Infimab Injection 1's and Fingolimod together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain contact a doctor right away. Do not stop using any medications without a doctor's advice.
InfliximabMercaptopurine
Severe
How does the drug interact with Infimab Injection 1's:
Co-administration of Infimab Injection 1's with Mercaptopurine can increase the risk of infection.

How to manage the interaction:
Taking Mercaptopurine with Infimab Injection 1's together can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, contact your doctor right away. These symptoms include fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate. Do not discontinue any medications without consulting a doctor.
InfliximabPlicamycin
Severe
How does the drug interact with Infimab Injection 1's:
Using Infimab Injection 1's together with plicamycin may increase the risk of serious infections.

How to manage the interaction:
Taking Plicamycin with Infimab Injection 1's together can result in an interaction, but it can be taken if your doctor has advised it. Contact a doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to a doctor.
InfliximabCisplatin
Severe
How does the drug interact with Infimab Injection 1's:
Combining Infimab Injection 1's with Cisplatin can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Infimab Injection 1's with Cisplatin can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, a sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, contact a doctor right away. Do not stop using any medications without a doctor's advice.
InfliximabTemozolomide
Severe
How does the drug interact with Infimab Injection 1's:
Taking Temozolomide with Infimab Injection 1's can increase the risk of infections.

How to manage the interaction:
Although taking temozolomide and Infimab Injection 1's together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
InfliximabDaunorubicin
Severe
How does the drug interact with Infimab Injection 1's:
Combining Infimab Injection 1's with Daunorubicin can increase the risk or severity of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Infimab Injection 1's and Daunorubicin, but it can be taken if prescribed by a doctor. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee contact a doctor right away. Do not stop using any medications without talking to a doctor.
InfliximabTriamcinolone
Severe
How does the drug interact with Infimab Injection 1's:
Taking Infimab Injection 1's with triamcinolone can increase the risk or severity of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Triamcinolone and Infimab Injection 1's, you can take these medicines together if prescribed by your doctor. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
InfliximabOfatumumab
Severe
How does the drug interact with Infimab Injection 1's:
Combining Infimab Injection 1's with Ofatumumab can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Ofatumumab with Infimab Injection 1's can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you pee, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
InfliximabEpirubicin
Severe
How does the drug interact with Infimab Injection 1's:
Combining Infimab Injection 1's with Epirubicin can increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Infimab Injection 1's with Epirubicin together can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, contact a doctor right away. Do not stop using any medications without a doctor's advice.
InfliximabThalidomide
Severe
How does the drug interact with Infimab Injection 1's:
Taking Thalidomide with Infimab Injection 1's may increase the risk of infection.

How to manage the interaction:
Although taking thalidomide and Infimab Injection 1's together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching that is less likely to spasm, tear and sprain.
  • Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well and get plenty of sleep.
  • Stay hydrated; drink plenty of water.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Infimab Injection Substitute

Substitutes safety advice
  • Remicade 100 mg Injection 1's

    18056.70per tablet
  • Inflixirel 100 mg Injection 1's

    32990.00per tablet
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Infimab Injection. Please consult the doctor.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before receiving Infimab Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

It is not known whether Infimab Injection passes into human milk. Hence, if you are breastfeeding, inform your doctor before receiving Infimab Injection.

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Driving

Caution

Infimab Injection will be administered in the hospital setting. Hence, driving and operating machines is not recommended.

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Liver

Caution

If you have liver disease, inform your doctor before receiving Infimab Injection. Some patients using $namr have suffered significant liver issues in rare situations. Inform your doctor if you have jaundice (yellowing skin and eyes), dark brown urine discomfort (right-sided abdominal ache, extreme exhaustion (severe fatigue) as a result of a fever.

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Kidney

Caution

If you have kidney impairment, tell your doctor before taking Infimab Injection.

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Children

Safe if prescribed

Infimab Injection is not recommended in children below six years of age as safety and efficacy are not established. In children above six years of age, it will be administered by the pediatrician. Infimab Injection is used in children only for the treatment of juvenile idiopathic arthritis, paediatric Crohn’s disease, and ulcerative colitis.

FAQs

Infimab Injection is used to treat Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis, Plaque psoriasis, Crohn’s disease and Ulcerative colitis.
Infimab Injection contains Infliximab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive.
Infimab Injection affects your immune system and makes you more susceptible to infections. Hence, it is not recommended for patients with active infections like tuberculosis or abnormal liver enzymes. Infimab Injection can also increase the risk of developing cancers; hence, informing your doctor if you have a history of any cancer is essential.
Yes, Infimab Injection is an immunosuppressant. It works by inhibiting the action of tumour necrosis factor-alpha (TNF-alpha), a protein that promotes inflammation and immune responses. By suppressing the immune system, Infimab Injection can help reduce inflammation and alleviate symptoms of autoimmune diseases.
Infimab Injection is a highly effective treatment for autoimmune diseases, offering many benefits that can outweigh its potential side effects. With proper medical care, you can minimize risks and maximize benefits, improving symptoms, increased mobility, and a better quality of life.
A healthcare provider administers Infimab Injection through an intravenous (IV) injection into your vein. The first dose is typically given over a period of 2 hours. Your doctor will determine the correct dose and schedule for your treatment. Please do not attempt to administer it yourself.
Yes, Infimab Injection can cause liver damage in some people, though it is rare. If you have pre-existing liver conditions like hepatitis, your doctor may monitor your liver function more closely during treatment. Be sure to report any symptoms, such as unexplained fatigue, yellowing of the skin or eyes (jaundice), dark urine, or pain in the upper right abdomen, as these could indicate liver problems.
While Infimab Injection can have potential effects on the heart, it's essential to note that these risks are rare and typically occur within 24 hours of starting treatment. You can minimise possible risks and ensure safe treatment by closely monitoring your heart health and promptly reporting any symptoms to your doctor.
Many patients start to notice relief from symptoms within 2 to 8 weeks, but it can vary depending on the condition being treated and how your body responds to the medication. In some cases, it may take several months or longer to feel the full effects. Follow your doctor's instructions and attend follow-up appointments to track your progress.
There is no clear evidence to suggest that alcohol directly interacts with Infimab Injection. However, since alcohol can affect your immune system and overall health, it is important to be cautious. Please consult your doctor for more information.
Infimab Injection may cause common side effects such as nausea, headache, back pain, upper respiratory tract infections, vision problems, dizziness, pale skin, numbness, chest pain, rash, and injection site reactions. Most of these side effects do not require medical attention or resolve over time. However, if they persist for longer, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - INF0228

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