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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Hodpro 50mg Capsule is an anti-cancer medicine used in the treatment of Hodgkin's lymphoma and certain brain tumors. This medicine works by inhibiting the proteins and DNA necessary for cell growth and division, thereby reducing the further growth of cancerous cells. Common side effects include nausea, vomiting, bruising, cramps, rash and loss of appetite.
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Whats That

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Composition :

PROCARBAZINE-50MG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Hodpro 50mg Capsule

Hodpro 50mg Capsule belongs to the group of anti-cancer drugs and chemotherapeutic agents. Hodpro 50mg Capsule is used to treat cancers and malignant conditions such as Hodgkin’s disease (cancer that originates in the white blood cells) and certain brain tumours.

Hodpro 50mg Capsule contains ‘’Procarbazine.’’ Cancer is an uncontrolled growth of cells in the body. Hodpro 50mg Capsule interferes with the growth of cells, nipping it in the bud. It functions by inhibiting the molecular production of materials such as proteins and DNA necessary for cell growth and division.

Hodpro 50mg Capsule is a prescription-only medicine. It may be taken as a tablet at the same time every day. Hodpro 50mg Capsule may be taken with or without food. It should be swallowed as a whole and not chewed or broken down. Avoid consuming Hodpro 50mg Capsule with certain foods like cheese, smoked fish, fermented wine and meat.

In some cases, Hodpro 50mg Capsule may cause common side effects such as nausea, vomiting, bruising, cramps, rash and loss of appetite. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist.

It is advisable to inform your doctor if you are allergic to Hodpro 50mg Capsule or any of its components. Keep your doctor informed if you suffer from kidney or liver disease, bleeding problems, anaemia or recurrent infections. Keep your doctor informed if you are on any radiation therapy. Consult your doctor if you are pregnant, planning pregnancy or breastfeeding before taking Hodpro 50mg Capsule as Hodpro 50mg Capsule is not recommended for routine use in these states. Consult your doctor before taking alcohol with Hodpro 50mg Capsule as there may be an interaction. Avoid smoking while taking Hodpro 50mg Capsule .

Uses of Hodpro 50mg Capsule

Treatment of Hodgkin's Lymphoma.

Directions for Use

Take Hodpro 50mg Capsule as directed by the physician. Hodpro 50mg Capsule should be swallowed as a whole. Do not crush, chew or break it. Hodpro 50mg Capsule can be taken with or without food, but it is better to take it with food. Avoid tyramine-rich foods such as processed cheese, smoked fish and meats, overripe fruit, fermented wine and non-alcoholic beer with Hodpro 50mg Capsule intake. In case you have missed a dose, take it as soon as you remember unless it is too close to the time of the second dose. Do not take a double dose in any case. Do not stop taking Hodpro 50mg Capsule abruptly and/or without the supervision of your physician.

Medicinal Benefits

Hodpro 50mg Capsule is an antineoplastic/anti-cancer drug. It contains PROCARBAZINE. It is used primarily in the treatment of cancers, especially Hodgkin’s lymphoma. Hodpro 50mg Capsule shows antineoplastic activity, meaning it targets neoplastic (abnormally growing cells) in the body and inhibits their uncontrolled division and growth. Hodpro 50mg Capsule works by preventing DNA, RNA and protein synthesis required for the molecular development of cells. Hodpro 50mg Capsule also acts by destroying DNA, thereby arresting cell growth in the roots. Hence, Hodpro 50mg Capsule is very effective in cancer therapy.

How Hodpro 50mg Capsule Works

Hodpro 50mg Capsule contains ‘’Procarbazine.’’ Cancer is an uncontrolled growth of cells in the body. Hodpro 50mg Capsule interferes with the growth of cells, nipping it in the bud. It functions by inhibiting the molecular production of materials such as proteins and DNA necessary for cell growth and division.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Hodpro 50mg Capsule

  • Vomiting
  • Nausea
  • Stomach cramps
  • Rash             
  • Bruising
  • Loss of appetite
  • Hair loss
  • Joint pains
  • Difficulty sleeping

What if I have taken an overdose of Hodpro 50mg Capsule

Take Hodpro 50mg Capsule only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. Overdose symptoms may include vomiting, diarrhoea, feeling lightheaded or tremors. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Hodpro 50mg Capsule should not be used in case of any known allergy to either of the components. Avoid foods such as processed cheese, smoked fish, meats, overripe fruit, fermented wine, and yeast while taking Hodpro 50mg Capsule . Hodpro 50mg Capsule should be used with caution in case of high-risk or previous history cancers, cardiovascular health disorders, bleeding disorders, kidney disease, liver disease or anaemia. Keep your doctor informed of your medical history and if you suffer from epilepsy, an adrenal tumour such as phaeochromocytoma, or have had a stroke. Consult your doctor before using Hodpro 50mg Capsule during pregnancy, breastfeeding, or even if you are trying to get pregnant. Keep your doctor informed if you are on painkillers or using any nasal decongestants or anti-anxiety, anti-depressant, antiepileptic, anaesthetic or analgesic medications. Keep your doctor informed in case you are undergoing any radiation therapy. Inform your doctor of your vaccination history and do not take any vaccines without consent. Avoid contact with those who have recently received live vaccines (like the nasal flu, pox, or MMR vaccine). Hodpro 50mg Capsule makes your skin more sensitive to UV radiation. Wear sunscreen and protective clothing while venturing out in the sun. Hodpro 50mg Capsule may interact with alcohol, please consult your doctor before use. Hodpro 50mg Capsule may cause dizziness and is not recommended to take while driving or operating heavy machinery.

Drug-Drug Interactions

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ProcarbazineDextromethorphan
Critical
ProcarbazineDesvenlafaxine
Critical

Drug-Drug Interactions

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ProcarbazineDextromethorphan
Critical
How does the drug interact with Hodpro 50mg Capsule:
Co-administration of Dextromethorphan and Hodpro 50mg Capsule may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Hodpro 50mg Capsule with Dextromethorphan can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
ProcarbazineDesvenlafaxine
Critical
How does the drug interact with Hodpro 50mg Capsule:
Combining Hodpro 50mg Capsule and Desvenlafaxine can increase the risk of a rare but serious condition called the serotonin syndrome.(A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Hodpro 50mg Capsule and Desvenlafaxine together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, contact your doctor immediately. you should wait at least 14 days after stopping isocarboxazid before you start treatment with desvenlafaxine and do not discontinue any medications without first consulting your doctor.
ProcarbazineBuspirone
Critical
How does the drug interact with Hodpro 50mg Capsule:
Combining Hodpro 50mg Capsule with Buspirone can increase the risk of high blood pressure.

How to manage the interaction:
Taking Buspirone with Hodpro 50mg Capsule is not recommended, as it results in an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor’s advice
ProcarbazineAmitriptyline
Critical
How does the drug interact with Hodpro 50mg Capsule:
Using Amitriptyline together with Hodpro 50mg Capsule can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Hodpro 50mg Capsule and Amitriptyline together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken amitriptyline. Do not discontinue any medications without consulting a doctor.
ProcarbazineEphedrine
Critical
How does the drug interact with Hodpro 50mg Capsule:
Taking Ephedrine and Hodpro 50mg Capsule together can increase the risk of high blood pressure.

How to manage the interaction:
Taking Ephedrine and Hodpro 50mg Capsule together is not recommended as it can result in an interaction, it can be taken if a doctor has prescribed it. However, if you develop a sudden, severe headache, blurred vision, disorientation, seizures, chest pain, nausea, or vomiting, sudden numbness or weakness (particularly on one side of the body), difficulty speaking, fever, sweating, lightheadedness, or fainting, you should consult the doctor. Do not discontinue any medications without a doctor's advice.
ProcarbazineVilazodone
Critical
How does the drug interact with Hodpro 50mg Capsule:
When Vilazodone is taken with Hodpro 50mg Capsule, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Vilazodone with Hodpro 50mg Capsule together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
ProcarbazineCarbamazepine
Critical
How does the drug interact with Hodpro 50mg Capsule:
Taking Carbamazepine with Hodpro 50mg Capsule may cause serotonin syndrome(a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Carbamazepine with Hodpro 50mg Capsule is generally not advised, it can be taken if prescribed by your doctor. However, if you experience symptoms such as confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
ProcarbazineTetrabenazine
Critical
How does the drug interact with Hodpro 50mg Capsule:
Coadministration of Hodpro 50mg Capsule and Tetrabenazine can increase the risk of high blood pressure.

How to manage the interaction:
Taking Hodpro 50mg Capsule and Tetrabenazine together is not recommended as it can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness, speech difficulties, fever, sweating, lightheadedness, and fainting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
ProcarbazineSertraline
Critical
How does the drug interact with Hodpro 50mg Capsule:
When Hodpro 50mg Capsule is taken with Sertraline, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Sertraline and Hodpro 50mg Capsule, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
ProcarbazineDuloxetine
Critical
How does the drug interact with Hodpro 50mg Capsule:
Taking duloxetine with Hodpro 50mg Capsule can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Duloxetine with Hodpro 50mg Capsule is not recommended, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering or shaking, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Keep your doctor informed if you are planning to or are pregnant.

  • Cancer can take a toll on anyone. Make sure you regularly see a therapist and take care of your mental health.

  • Meditation and yoga have also proven very effective in helping cancer patients maintain a healthy attitude and body.

  • Cut back on foods that are high in tyramine such as overripe fruit, processed cheese, smoked fish, meat etc. Eat more healthy meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy.

  • Avoid taking Hodpro 50mg Capsule with alcohol as there may be an interaction.

  • Stay hydrated by drinking plenty of water as dehydration is often seen in cancers.

  • Taking a stroll in the garden, or spending 30 mins of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired.

  • Avoid tobacco use as smoking can increase the chances of lung cancer when used with Hodpro 50mg Capsule . Inform your doctor in case of marijuana use.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Hodpro 50mg Capsule Substitute

Substitutes safety advice
  • Procarb 50mg Tablet

    by Others

    262.40per tablet
  • Glocarbazin 50mg Tablet

    by Others

    1.80per tablet
  • P Carzine 50mg Capsule

    by Others

    30.33per tablet
  • Zinocarb 50mg Capsule

    by Others

    31.50per tablet
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Alcohol

Unsafe

Do not consume alcohol with Hodpro 50mg Capsule as there may be an interaction, causing vomiting, cramps, sweating and flushing of the face. Please consult your doctor if you have any concerns.

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Pregnancy

Unsafe

Hodpro 50mg Capsule is not recommended for use in pregnancy. It is not safe during the first trimester. If you are pregnant, inform your doctor before taking Hodpro 50mg Capsule .

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Breast Feeding

Unsafe

Hodpro 50mg Capsule is not recommended for use during breastfeeding. Please consult your doctor if you have any concerns.

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Driving

Caution

Hodpro 50mg Capsule may cause dizziness or loss of alertness, which may affect your ability to drive.

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Liver

Caution

Hodpro 50mg Capsule is not recommended for use if you have pre-existing liver disease. Hence, please consult your doctor before taking this medicine.

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Kidney

Caution

Hodpro 50mg Capsule is not recommended for use if you have pre-existing kidney disease. Hence, please consult your doctor before taking this medicine.

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Children

Caution

Hodpro 50mg Capsule should be used with caution and only in prescribed doses in children below 12 years of age. Please consult your child's doctor if you have any concerns.

FAQs

Hodpro 50mg Capsule belongs to the group of anti-cancer drugs and chemotherapeutic agents. Hodpro 50mg Capsule is used to treat cancers and malignant conditions such as Hodgkins disease (cancer that originates in the white blood cells) and certain brain tumours.
Hodpro 50mg Capsule works by reducing the workload on the heart and vessels and relaxing the vessels to ensure a fluid flow of blood, easing any hypertension and effects of the same.
Please consult your physician before altering your chemotherapy as any misguided change can cause serious side effects. One of the side effects of Hodpro 50mg Capsule is also hair loss. Hence it is best to discuss your treatment plan with your doctor.
If you suffer from IBD, you may be on anticholinergic therapy which may interfere with Hodpro 50mg Capsule . Please consult your doctor before use and discuss any concerns with your doctor.
Hodpro 50mg Capsule is known to play a role in the treatment of various types of cancer, however, it is not routinely indicated in the treatment of breast cancer. Only proceed once a doctor has prescribed the same because the treatment for breast cancer is nuanced.
Hodpro 50mg Capsule is known to affect fertility. Avoid Hodpro 50mg Capsule if you are trying to get pregnant. Please consult your doctor in case of any concerns.

Country of origin

INDIA

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - HOD0001

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