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  3. Hickzee Tablet

Hickzee Tablet, Pack of 10 TabletS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Hickzee Tablet is used as an adjunct to treat Parkinson's disease and extrapyramidal symptoms (drug-induced movement disorders). It contains Trihexyphenidyl, which works by relaxing the muscles and nerve impulses that control muscle functioning. Besides this, it also balances chemical messengers called neurotransmitters in the brain; thereby improving muscle control and reducing stiffness. In some cases, you may experience common side effects such as nausea, vomiting, dizziness, constipation, weakness, headache, dry mouth, decreased urination, drowsiness, and feeling nervous or restless. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

TRIHEXYPHENIDYL-2MG

Manufacturer/Marketer :

Macway Biotech Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Hickzee Tablet

Hickzee Tablet is used as an adjunct to treat Parkinson’s disease and extrapyramidal symptoms (drug-induced movement disorders). Parkinson’s disease is a progressive neurological disorder in which the first signs are problems with movements. 

Hickzee Tablet contains ‘Trihexyphenidyl’, which works by relaxing the muscles and nerve impulses that control muscle functioning. Besides this, Hickzee Tablet also balances chemical messengers called neurotransmitters in the brain, thereby improving muscle control and reducing stiffness, thereby helping the muscles move naturally. 

In some cases, you may experience common side effects such as nausea, vomiting, dizziness, constipation, weakness, headache, dry mouth, decreased urination, drowsiness, and feeling nervous or restless. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Consult your doctor if you are pregnant or breastfeeding. Hickzee Tablet may cause drowsiness and dizziness; do not drive unless you are alert. Hickzee Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Hickzee Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your medicines and health conditions to rule out any side effects.

Uses of Hickzee Tablet

Treatment of Parkinson's disease.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew or crush the tablet/capsule.Dispersible tablet: Disperse the tablet in water and consume it.

Medicinal Benefits

Hickzee Tablet belongs to a group of medicines called anti-spasmodic agents. Hickzee Tablet is used to treat the symptoms of Parkinson’s disease and extrapyramidal symptoms (drug-induced movement disorders). Hickzee Tablet exerts a direct inhibitory effect upon the parasympathetic nervous system. It works by relaxing the muscles and nerve impulses that control muscle functioning. Hickzee Tablet improves muscle control and reduces stiffness, thereby helping the muscles move naturally. Hickzee Tablet is used as an adjuvant therapy along with levodopa to treat Parkinson's disease. Additionally, Hickzee Tablet is used to control drug-induced movement disorders caused by CNS drugs such as dibenzoxazepines, thioxanthenes, phenothiazines, and butyrophenones.

How Hickzee Tablet Works

Hickzee Tablet contains ‘Trihexyphenidyl’, which works by relaxing the muscles and nerve impulses that control muscle functioning. Besides this, Hickzee Tablet also balances chemical messengers called neurotransmitters in the brain, thereby improving muscle control and reducing stiffness, thereby helping the muscles move naturally.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Hickzee Tablet

  • Nausea
  • Vomiting
  • Dizziness
  • Constipation
  • Weakness 
  • Headache
  • Dry mouth
  • Decreased urination
  • Drowsiness
  • Feeling nervous or restless

What if I have taken an overdose of Hickzee Tablet

Do not take more than the prescribed dose of Hickzee Tablet as it may cause overdose. The symptoms of overdose include feeling hot, paleness in face, severe drowsiness, fever, dilated pupils, dry skin and mouth, seizure, hallucinations, paranoia, agitation, or numbness in or around your mouth, nose, or throat. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Hickzee Tablet if you are allergic to any of its contents or if you have narrow-angle glaucoma. Do not discontinue Hickzee Tablet on your own. Inform your doctor if you have glaucoma, prostate problems, urination problems, stomach ulcers, acidity, myasthenia gravis (muscle problems), tardive dyskinesia (involuntary facial movements), alcoholism, high blood pressure, heart, liver or kidney problems. Talk to your doctor immediately if you experience hallucinations. Consult your doctor if you are pregnant or breastfeeding. Hickzee Tablet may cause drowsiness and dizziness, do not drive unless you are alert. Hickzee Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Hickzee Tablet as it could lead to increased drowsiness and dizziness.

Drug-Drug Interactions

verifiedApollotooltip
TrihexyphenidylPotassium citrate
Critical
TrihexyphenidylPotassium chloride
Critical

Drug-Drug Interactions

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TrihexyphenidylPotassium citrate
Critical
How does the drug interact with Hickzee Tablet:
Co-administration of Hickzee Tablet with potassium citrate may increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Hickzee Tablet with potassium citrate is not recommended as it can possibly result in an interaction, it can be taken if prescribed by a doctor. However, if you experience abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, or black stools contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TrihexyphenidylPotassium chloride
Critical
How does the drug interact with Hickzee Tablet:
Co-administration of Hickzee Tablet with potassium chloride can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Hickzee Tablet with potassium chloride is not recommended as it can possibly result in an interaction, it can be taken if prescribed by a doctor. However, if you experience abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, black stools contact a doctor immediately. Do not discontinue any medications without consulting to a doctor.
TrihexyphenidylAmantadine
Severe
How does the drug interact with Hickzee Tablet:
Coadministration of Allopurinol with Hickzee Tablet may increase side effects such as heat intolerance, dry mouth, confusion, constipation, difficulty urinating, and blurred vision especially in the elderly or those with a debilitating (physically weak) condition.

How to manage the interaction:
If you are supposed to take Allopurinol and Hickzee Tablet together, your doctor may adjust the dose or monitor you more frequently to safely use both medications.
TrihexyphenidylZonisamide
Severe
How does the drug interact with Hickzee Tablet:
Coadministration of Hickzee Tablet with Zonisamide can increase the risk or severity of Zonisamide side effects like increased body temperature and decreased sweating especially in warm weather.

How to manage the interaction:
Taking Hickzee Tablet with Zonisamide together is not recommended as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
TrihexyphenidylEsketamine
Severe
How does the drug interact with Hickzee Tablet:
Taking Hickzee Tablet with esketamine can increase the risk of other side effects.

How to manage the interaction:
Although there is a interaction between Hickzee Tablet and esketamine, but can be taken together if prescribed by your doctor. However, if you experience drowsiness, confusion, difficulty concentrating, and impairment in thinking contact your doctor right away. Do not stop using any medications without talking to your doctor.
TrihexyphenidylTopiramate
Severe
How does the drug interact with Hickzee Tablet:
Taking Hickzee Tablet with topiramate can increase the risk of increase body temperature and reduced sweating.

How to manage the interaction:
Co-administration of Hickzee Tablet with Topiramate can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience dizziness or lightheaded, increase body temperature contact your doctor right away. Do not discontinue any medications without first consulting your doctor.
TrihexyphenidylKetamine
Severe
How does the drug interact with Hickzee Tablet:
Taking Hickzee Tablet with Ketamine can increase the risk of side effects.

How to manage the interaction:
Although there is a interaction between Hickzee Tablet and ketamine, but it can be taken together if prescribed by your doctor. However, if you experience drowsiness, confusion, difficulty concentrating, and impairment in thinking contact your doctor right away. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly.
  • Include a diet rich in iron, folate and magnesium. 
  • Regularly attend therapy sessions.
  • Perform meditation and yoga.
  • Follow a regular sleep pattern.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

ANTIPARKINSON AGENTS

Hickzee Tablet Substitute

Substitutes safety advice

  • Pacitane Tablet 30's

    by Others

    ₹1.52per tablet

  • Parkin 2 mg Tablet 15's

    by Others

    ₹1.35per tablet

  • Bexol DT Tablet 100's

    by Others

    ₹1.38per tablet

  • Bexol Tablet 10's

    by Others

    ₹1.35per tablet

  • Parnil-2 Tablet 10's

    by Others

    ₹1.35per tablet

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Hickzee Tablet as it may cause increased dizziness and drowsiness.

bannner image

Pregnancy

Caution

Hickzee Tablet belongs to pregnancy category C. Please consult your doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Hickzee Tablet passes into breastmilk. Consult your doctor if you are breastfeeding.

bannner image

Driving

Unsafe

Hickzee Tablet may cause dizziness, drowsiness and blurred vision. Avoid driving and handling machinery if you experience these symptoms.

bannner image

Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Unsafe

Hickzee Tablet is not recommended for use in children, as safety and effectiveness have not been established.

FAQs

Hickzee Tablet belongs to a group of medicines called anti-spasmodic agents used as an adjunct to treat Parkinson’s disease and extrapyramidal symptoms (drug-induced movement disorders).

Hickzee Tablet works by relaxing the muscles and nerve impulses that control muscle functioning. It improves muscle control and reduces the stiffness, thereby helps the muscles move naturally.

Dry mouth could be a side-effect of Hickzee Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

Hickzee Tablet should be used with caution during hot weather as it may increase the chance of having a heat stroke. Inform your doctor if you have heat intolerance or fever.

Antidepressants should be avoided while taking Hickzee Tablet as it might increase sedative effects. Consult your doctor before taking Hickzee Tablet if you are using depressants.

Hallucination is a medical condition in which the person may feel, hear or believe things that are not true, see things that are not there, or feel unusually suspicious or confused. Hickzee Tablet may cause hallucinations in some cases if taken for a prolonged time. So, if you experience hallucinations while taking Hickzee Tablet, please talk to your doctor immediately.

Constipation may occur as a side-effect of Hickzee Tablet. Try eating foods that encourage a bowel movement. Consult your doctor if you experience excessive constipation.

Consult your doctor before taking Hickzee Tablet if you have glaucoma. Hickzee Tablet is contraindicated in patients with narrow-angle glaucoma. Hickzee Tablet may cause blindness on long-term use in case of patients with narrow-angle glaucoma.

The dosage and frequency of taking Hickzee Tablet depend on various factors, including age, weight, medical condition, severity of symptoms, and other medications being taken. So, it's essential to follow the specific instructions provided by your doctor.

Don't stop taking Hickzee Tablet without consulting your doctor. Stopping suddenly can cause withdrawal symptoms and worsen your condition. If you're doing well, report to your doctor for further guidance. Contact your doctor immediately for appropriate treatment if you experience any difficulties or side effects. Your doctor will help you adjust your medication safely and effectively.

Before starting Hickzee Tablet, it's crucial to have a thorough consultation with your doctor. Share your comprehensive medical history, including any existing conditions or past illnesses. Also, provide a detailed list of your medications and supplements. Inform your doctor about any medication allergies or sensitivities. Furthermore, discuss your lifestyle habits, such as smoking, alcohol consumption, or recreational drug use. If you're pregnant, breastfeeding, or planning to become pregnant, be sure to disclose this information. This will enable your doctor to determine whether Hickzee Tablet suits you and provide personalized care.

Swallow it whole with a glass of water. Do not chew or crush the tablet or capsule. It's important to follow your doctor's exact directions, including the recommended dose and duration of treatment.

The common side effects of Hickzee Tablet include nausea, vomiting, dizziness, constipation, weakness, headache, dry mouth, decreased urination, drowsiness, and feeling nervous or restless. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

MACWAYHOUSE, HNO.4-7-11/9 RAGHAVENDRA NAGAR, NACHARAM, HYDERABAD - 500076, Telangana, India.
Other Info - HIC0064

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Author Details

Doctor imageDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Doctor imageDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:49 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.5271.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/nda/2003/006773_S036_ARTANE.pdf
  3. https://medlineplus.gov/druginfo/meds/a682160.html
  4. https://www.drugs.com/mtm/trihexyphenidyl.html
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