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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Parkin 2 Tablet is used as an adjunct to treat Parkinson's disease and extrapyramidal symptoms (drug-induced movement disorders). It contains Trihexyphenidyl, which works by relaxing the muscles and nerve impulses that control muscle functioning. Besides this, it also balances chemical messengers called neurotransmitters in the brain; thereby improving muscle control and reducing stiffness. In some cases, you may experience common side effects such as nausea, vomiting, dizziness, constipation, weakness, headache, dry mouth, decreased urination, drowsiness, and feeling nervous or restless. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Parkin 2 mg Tablet 10's, Pack of 10 TABLETS
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Prescription drug

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Composition :

TRIHEXYPHENIDYL-2MG

Manufacturer/Marketer :

Micro Labs Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

Parkin 2 Tablet is used as an adjunct to treat Parkinson’s disease and extrapyramidal symptoms (drug-induced movement disorders). Parkinson’s disease is a progressive neurological disorder in which the first signs are problems with movements. 

Parkin 2 Tablet contains ‘Trihexyphenidyl’, which works by relaxing the muscles and nerve impulses that control muscle functioning. Besides this, Parkin 2 Tablet also balances chemical messengers called neurotransmitters in the brain, thereby improving muscle control and reducing stiffness, thereby helping the muscles move naturally. 

In some cases, you may experience common side effects such as nausea, vomiting, dizziness, constipation, weakness, headache, dry mouth, decreased urination, drowsiness, and feeling nervous or restless. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Consult your doctor if you are pregnant or breastfeeding. Parkin 2 Tablet may cause drowsiness and dizziness; do not drive unless you are alert. Parkin 2 Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Parkin 2 Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your medicines and health conditions to rule out any side effects.

Treatment of Parkinson's disease.
Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew or crush the tablet/capsule.Dispersible tablet: Disperse the tablet in water and consume it.

Parkin 2 Tablet belongs to a group of medicines called anti-spasmodic agents. Parkin 2 Tablet is used to treat the symptoms of Parkinson’s disease and extrapyramidal symptoms (drug-induced movement disorders). Parkin 2 Tablet exerts a direct inhibitory effect upon the parasympathetic nervous system. It works by relaxing the muscles and nerve impulses that control muscle functioning. Parkin 2 Tablet improves muscle control and reduces stiffness, thereby helping the muscles move naturally. Parkin 2 Tablet is used as an adjuvant therapy along with levodopa to treat Parkinson's disease. Additionally, Parkin 2 Tablet is used to control drug-induced movement disorders caused by CNS drugs such as dibenzoxazepines, thioxanthenes, phenothiazines, and butyrophenones.

Parkin 2 Tablet contains ‘Trihexyphenidyl’, which works by relaxing the muscles and nerve impulses that control muscle functioning. Besides this, Parkin 2 Tablet also balances chemical messengers called neurotransmitters in the brain, thereby improving muscle control and reducing stiffness, thereby helping the muscles move naturally.
Store in a cool and dry place away from sunlight
  • Nausea
  • Vomiting
  • Dizziness
  • Constipation
  • Weakness 
  • Headache
  • Dry mouth
  • Decreased urination
  • Drowsiness
  • Feeling nervous or restless
Do not take more than the prescribed dose of Parkin 2 Tablet as it may cause overdose. The symptoms of overdose include feeling hot, paleness in face, severe drowsiness, fever, dilated pupils, dry skin and mouth, seizure, hallucinations, paranoia, agitation, or numbness in or around your mouth, nose, or throat. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Do not take Parkin 2 Tablet if you are allergic to any of its contents or if you have narrow-angle glaucoma. Do not discontinue Parkin 2 Tablet on your own. Inform your doctor if you have glaucoma, prostate problems, urination problems, stomach ulcers, acidity, myasthenia gravis (muscle problems), tardive dyskinesia (involuntary facial movements), alcoholism, high blood pressure, heart, liver or kidney problems. Talk to your doctor immediately if you experience hallucinations. Consult your doctor if you are pregnant or breastfeeding. Parkin 2 Tablet may cause drowsiness and dizziness, do not drive unless you are alert. Parkin 2 Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Parkin 2 Tablet as it could lead to increased drowsiness and dizziness.

verifiedApollotooltip
TrihexyphenidylPotassium citrate
Critical
TrihexyphenidylPotassium chloride
Critical

Drug-Drug Interactions

TrihexyphenidylPotassium citrate
Critical
How does the drug interact with Parkin 2 Tablet 10's:
Co-administration of Parkin 2 Tablet 10's with potassium citrate may increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Parkin 2 Tablet 10's with potassium citrate is not recommended as it can possibly result in an interaction, it can be taken if prescribed by a doctor. However, if you experience abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, or black stools contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TrihexyphenidylPotassium chloride
Critical
How does the drug interact with Parkin 2 Tablet 10's:
Co-administration of Parkin 2 Tablet 10's with potassium chloride can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Parkin 2 Tablet 10's with potassium chloride is not recommended as it can possibly result in an interaction, it can be taken if prescribed by a doctor. However, if you experience abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, black stools contact a doctor immediately. Do not discontinue any medications without consulting to a doctor.
TrihexyphenidylTopiramate
Severe
How does the drug interact with Parkin 2 Tablet 10's:
Taking Parkin 2 Tablet 10's with topiramate can increase the risk of increase body temperature and reduced sweating.

How to manage the interaction:
Co-administration of Parkin 2 Tablet 10's with Topiramate can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience dizziness or lightheaded, increase body temperature contact your doctor right away. Do not discontinue any medications without first consulting your doctor.
TrihexyphenidylAmantadine
Severe
How does the drug interact with Parkin 2 Tablet 10's:
Coadministration of Allopurinol with Parkin 2 Tablet 10's may increase side effects such as heat intolerance, dry mouth, confusion, constipation, difficulty urinating, and blurred vision especially in the elderly or those with a debilitating (physically weak) condition.

How to manage the interaction:
If you are supposed to take Allopurinol and Parkin 2 Tablet 10's together, your doctor may adjust the dose or monitor you more frequently to safely use both medications.
TrihexyphenidylKetamine
Severe
How does the drug interact with Parkin 2 Tablet 10's:
Taking Parkin 2 Tablet 10's with Ketamine can increase the risk of side effects.

How to manage the interaction:
Although there is a interaction between Parkin 2 Tablet 10's and ketamine, but it can be taken together if prescribed by your doctor. However, if you experience drowsiness, confusion, difficulty concentrating, and impairment in thinking contact your doctor right away. Do not stop using any medications without talking to your doctor.
TrihexyphenidylZonisamide
Severe
How does the drug interact with Parkin 2 Tablet 10's:
Coadministration of Parkin 2 Tablet 10's with Zonisamide can increase the risk or severity of Zonisamide side effects like increased body temperature and decreased sweating especially in warm weather.

How to manage the interaction:
Taking Parkin 2 Tablet 10's with Zonisamide together is not recommended as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
TrihexyphenidylEsketamine
Severe
How does the drug interact with Parkin 2 Tablet 10's:
Taking Parkin 2 Tablet 10's with esketamine can increase the risk of other side effects.

How to manage the interaction:
Although there is a interaction between Parkin 2 Tablet 10's and esketamine, but can be taken together if prescribed by your doctor. However, if you experience drowsiness, confusion, difficulty concentrating, and impairment in thinking contact your doctor right away. Do not stop using any medications without talking to your doctor.
verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

  • Maintain a healthy diet and exercise regularly.
  • Include a diet rich in iron, folate and magnesium. 
  • Regularly attend therapy sessions.
  • Perform meditation and yoga.
  • Follow a regular sleep pattern.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.
No
ANTIPARKINSON AGENTS

Parkin 2 Tablet Substitute

Substitutes safety advice

  • Pacitane Tablet 30's

    ₹1.52per tablet

  • Parkin 2 mg Tablet 15's

    ₹1.38per tablet

  • Bexol DT Tablet 100's

    ₹1.38per tablet

  • Bexol Tablet 10's

    ₹1.35per tablet

  • Parnil-2 Tablet 10's

    ₹1.35per tablet
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Pacitane Tablet 30's

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Parkin 2 mg Tablet 15's

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Bexol DT Tablet 100's

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Bexol Tablet 10's

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Parnil-2 Tablet 10's

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Hexylent Tablet 10's

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ECITANE TABLET

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Pacipeace-2 mg Tablet 10's

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Trixpark-2 Tablet 10's

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Tremoxyl Tablet 10's

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Pacitrix Tablet 10's

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Hexitin Tablet 10's

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Movahexy Tablet 10's

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Trix Tablet 10's

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Tridyl 2 mg Tablet 10's

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Parkinta 2 mg DT Tablet 10's

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Unsafe

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Caution

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Caution

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Unsafe

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Caution

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Caution

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Unsafe

FAQs

Parkin 2 Tablet belongs to a group of medicines called anti-spasmodic agents used as an adjunct to treat Parkinson’s disease and extrapyramidal symptoms (drug-induced movement disorders).
Parkin 2 Tablet works by relaxing the muscles and nerve impulses that control muscle functioning. It improves muscle control and reduces the stiffness, thereby helps the muscles move naturally.
Dry mouth could be a side-effect of Parkin 2 Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.
Parkin 2 Tablet should be used with caution during hot weather as it may increase the chance of having a heat stroke. Inform your doctor if you have heat intolerance or fever.
Antidepressants should be avoided while taking Parkin 2 Tablet as it might increase sedative effects. Consult your doctor before taking Parkin 2 Tablet if you are using depressants.
Hallucination is a medical condition in which the person may feel, hear or believe things that are not true, see things that are not there, or feel unusually suspicious or confused. Parkin 2 Tablet may cause hallucinations in some cases if taken for a prolonged time. So, if you experience hallucinations while taking Parkin 2 Tablet , please talk to your doctor immediately.
Constipation may occur as a side-effect of Parkin 2 Tablet . Try eating foods that encourage a bowel movement. Consult your doctor if you experience excessive constipation.
Consult your doctor before taking Parkin 2 Tablet if you have glaucoma. Parkin 2 Tablet is contraindicated in patients with narrow-angle glaucoma. Parkin 2 Tablet may cause blindness on long-term use in case of patients with narrow-angle glaucoma.
The dosage and frequency of taking Parkin 2 Tablet depend on various factors, including age, weight, medical condition, severity of symptoms, and other medications being taken. So, it's essential to follow the specific instructions provided by your doctor.
Don't stop taking Parkin 2 Tablet without consulting your doctor. Stopping suddenly can cause withdrawal symptoms and worsen your condition. If you're doing well, report to your doctor for further guidance. Contact your doctor immediately for appropriate treatment if you experience any difficulties or side effects. Your doctor will help you adjust your medication safely and effectively.
Before starting Parkin 2 Tablet , it's crucial to have a thorough consultation with your doctor. Share your comprehensive medical history, including any existing conditions or past illnesses. Also, provide a detailed list of your medications and supplements. Inform your doctor about any medication allergies or sensitivities. Furthermore, discuss your lifestyle habits, such as smoking, alcohol consumption, or recreational drug use. If you're pregnant, breastfeeding, or planning to become pregnant, be sure to disclose this information. This will enable your doctor to determine whether Parkin 2 Tablet suits you and provide personalized care.
Swallow it whole with a glass of water. Do not chew or crush the tablet or capsule. It's important to follow your doctor's exact directions, including the recommended dose and duration of treatment.
The common side effects of Parkin 2 Tablet include nausea, vomiting, dizziness, constipation, weakness, headache, dry mouth, decreased urination, drowsiness, and feeling nervous or restless. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
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Reference

  1. https://www.medicines.org.uk/emc/files/pil.5271.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/nda/2003/006773_S036_ARTANE.pdf
  3. https://medlineplus.gov/druginfo/meds/a682160.html
  4. https://www.drugs.com/mtm/trihexyphenidyl.html
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