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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:50 PM IST
Hexytal 2mg Tablet is used as an adjunct to treat Parkinson's disease and extrapyramidal symptoms (drug-induced movement disorders). It contains Trihexyphenidyl, which works by relaxing the muscles and nerve impulses that control muscle functioning. Besides this, it also balances chemical messengers called neurotransmitters in the brain; thereby improving muscle control and reducing stiffness. In some cases, you may experience common side effects such as nausea, vomiting, dizziness, constipation, weakness, headache, dry mouth, decreased urination, drowsiness, and feeling nervous or restless. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Hexytal 2mg Tablet

Hexytal 2mg Tablet is used as an adjunct to treat Parkinson’s disease and extrapyramidal symptoms (drug-induced movement disorders). Parkinson’s disease is a progressive neurological disorder in which the first signs are problems with movements. 

Hexytal 2mg Tablet contains ‘Trihexyphenidyl’, which works by relaxing the muscles and nerve impulses that control muscle functioning. Besides this, Hexytal 2mg Tablet also balances chemical messengers called neurotransmitters in the brain, thereby improving muscle control and reducing stiffness, thereby helping the muscles move naturally. 

In some cases, you may experience common side effects such as nausea, vomiting, dizziness, constipation, weakness, headache, dry mouth, decreased urination, drowsiness, and feeling nervous or restless. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Consult your doctor if you are pregnant or breastfeeding. Hexytal 2mg Tablet may cause drowsiness and dizziness; do not drive unless you are alert. Hexytal 2mg Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Hexytal 2mg Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your medicines and health conditions to rule out any side effects.

Uses of Hexytal 2mg Tablet

Treatment of Parkinson's disease.

Medicinal Benefits

Hexytal 2mg Tablet belongs to a group of medicines called anti-spasmodic agents. Hexytal 2mg Tablet is used to treat the symptoms of Parkinson’s disease and extrapyramidal symptoms (drug-induced movement disorders). Hexytal 2mg Tablet exerts a direct inhibitory effect upon the parasympathetic nervous system. It works by relaxing the muscles and nerve impulses that control muscle functioning. Hexytal 2mg Tablet improves muscle control and reduces stiffness, thereby helping the muscles move naturally. Hexytal 2mg Tablet is used as an adjuvant therapy along with levodopa to treat Parkinson's disease. Additionally, Hexytal 2mg Tablet is used to control drug-induced movement disorders caused by CNS drugs such as dibenzoxazepines, thioxanthenes, phenothiazines, and butyrophenones.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew or crush the tablet/capsule.Dispersible tablet: Disperse the tablet in water and consume it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Hexytal 2mg Tablet

  • Nausea
  • Vomiting
  • Dizziness
  • Constipation
  • Weakness 
  • Headache
  • Dry mouth
  • Decreased urination
  • Drowsiness
  • Feeling nervous or restless

Drug Warnings

Do not take Hexytal 2mg Tablet if you are allergic to any of its contents or if you have narrow-angle glaucoma. Do not discontinue Hexytal 2mg Tablet on your own. Inform your doctor if you have glaucoma, prostate problems, urination problems, stomach ulcers, acidity, myasthenia gravis (muscle problems), tardive dyskinesia (involuntary facial movements), alcoholism, high blood pressure, heart, liver or kidney problems. Talk to your doctor immediately if you experience hallucinations. Consult your doctor if you are pregnant or breastfeeding. Hexytal 2mg Tablet may cause drowsiness and dizziness, do not drive unless you are alert. Hexytal 2mg Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Hexytal 2mg Tablet as it could lead to increased drowsiness and dizziness.

Drug Interactions

Drug-Drug Interactions: Hexytal 2mg Tablet may have interaction with antipsychotic (aripiprazole, lurasidone, olanzapine, risperidone, quetiapine, trifluoperazine), MAO inhibitor (rasagiline), antihistamine (diphenhydramine), anti-cholinergic (benztropine), anti-convulsant (clonazepam, lamotrigine, pregabalin), anti-depressants (escitalopram, duloxetine) anti-anxiety (alprazolam), and mild pain killers/fever-reducing agent (acetaminophen).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have arrhythmia (irregular heartbeats), autonomic neuropathy (nerve damage), gastrointestinal obstruction, glaucoma, urinary obstruction, infectious diarrhoea, tardive dyskinesia (involuntary facial movements), psychoses, high blood pressure, or fever.

Drug-Drug Interactions Checker List

  • ARIPIPRAZOLE
  • LURASIDONE
  • OLANZAPINE
  • RISPERIDONE
  • QUETIAPINE
  • TRIFLUOPERAZINE
  • RASAGILINE
  • DIPHENHYDRAMINE
  • BENZTROPINE MESYLATE
  • CLONAZEPAM
  • LAMOTRIGINE
  • PREGABALIN
  • ESCITALOPRAM
  • DULOXETINE
  • ALPRAZOLAM
  • ACETAMINOPHEN

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly.
  • Include a diet rich in iron, folate and magnesium. 
  • Regularly attend therapy sessions.
  • Perform meditation and yoga.
  • Follow a regular sleep pattern.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Special Advise

  • Take Hexytal 2mg Tablet at least 2 hours after taking ketoconazole and antidiarrheal medicines as it may prevent the full absorption of trihexyphenidyl. Besides this, Hexytal 2mg Tablet may prevent the complete absorption of antifungal agents like ketoconazole when these medicines are taken together.

  • Hexytal 2mg Tablet can cause decreased sweating, resulting in a rise in body temperature (hyperthermia). This profound side effect is more significant in hot weather, so it is advisable to drink plenty of water, especially in summer. However, kidney patients should consult a doctor before consuming any fluid.

  • Take special care with your dental hygiene while using Hexytal 2mg Tablet (like brushing, and flossing) and have regular dental check-ups.

Disease/Condition Glossary

Parkinson’s disease: It is a progressive neurological disorder in which the first signs are problems with movements. Dopamine is a naturally occurring neurotransmitter in the brain which is reduced or absent in people with Parkinson’s disease. Due to this, problems arise with smooth and coordinated movements. Symptoms include decreased ability to smell, stooped posture, changes in voice, constipation, small/ cramped handwriting, tremors, slow movements, stiffness of arms, legs, trunk, and balance problems. 

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Hexytal 2mg Tablet as it may cause increased dizziness and drowsiness.

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Pregnancy

Caution

Hexytal 2mg Tablet belongs to pregnancy category C. Please consult your doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Hexytal 2mg Tablet passes into breastmilk. Consult your doctor if you are breastfeeding.

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Driving

Unsafe

Hexytal 2mg Tablet may cause dizziness, drowsiness and blurred vision. Avoid driving and handling machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Hexytal 2mg Tablet is not recommended for use in children, as safety and effectiveness have not been established.

Country of origin

India
Other Info - HE77207

Author Details

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FAQs

Hexytal 2mg Tablet belongs to a group of medicines called anti-spasmodic agents used as an adjunct to treat Parkinson’s disease and extrapyramidal symptoms (drug-induced movement disorders).
Hexytal 2mg Tablet works by relaxing the muscles and nerve impulses that control muscle functioning. It improves muscle control and reduces the stiffness, thereby helps the muscles move naturally.
Dry mouth could be a side-effect of Hexytal 2mg Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.
Hexytal 2mg Tablet should be used with caution during hot weather as it may increase the chance of having a heat stroke. Inform your doctor if you have heat intolerance or fever.
Antidepressants should be avoided while taking Hexytal 2mg Tablet as it might increase sedative effects. Consult your doctor before taking Hexytal 2mg Tablet if you are using depressants.
Hallucination is a medical condition in which the person may feel, hear or believe things that are not true, see things that are not there, or feel unusually suspicious or confused. Hexytal 2mg Tablet may cause hallucinations in some cases if taken for a prolonged time. So, if you experience hallucinations while taking Hexytal 2mg Tablet, please talk to your doctor immediately.
Constipation may occur as a side-effect of Hexytal 2mg Tablet. Try eating foods that encourage a bowel movement. Consult your doctor if you experience excessive constipation.
Consult your doctor before taking Hexytal 2mg Tablet if you have glaucoma. Hexytal 2mg Tablet is contraindicated in patients with narrow-angle glaucoma. Hexytal 2mg Tablet may cause blindness on long-term use in case of patients with narrow-angle glaucoma.
The dosage and frequency of taking Hexytal 2mg Tablet depend on various factors, including age, weight, medical condition, severity of symptoms, and other medications being taken. So, it's essential to follow the specific instructions provided by your doctor.
Don't stop taking Hexytal 2mg Tablet without consulting your doctor. Stopping suddenly can cause withdrawal symptoms and worsen your condition. If you're doing well, report to your doctor for further guidance. Contact your doctor immediately for appropriate treatment if you experience any difficulties or side effects. Your doctor will help you adjust your medication safely and effectively.
Before starting Hexytal 2mg Tablet, it's crucial to have a thorough consultation with your doctor. Share your comprehensive medical history, including any existing conditions or past illnesses. Also, provide a detailed list of your medications and supplements. Inform your doctor about any medication allergies or sensitivities. Furthermore, discuss your lifestyle habits, such as smoking, alcohol consumption, or recreational drug use. If you're pregnant, breastfeeding, or planning to become pregnant, be sure to disclose this information. This will enable your doctor to determine whether Hexytal 2mg Tablet suits you and provide personalized care.
Swallow it whole with a glass of water. Do not chew or crush the tablet or capsule. It's important to follow your doctor's exact directions, including the recommended dose and duration of treatment.
The common side effects of Hexytal 2mg Tablet include nausea, vomiting, dizziness, constipation, weakness, headache, dry mouth, decreased urination, drowsiness, and feeling nervous or restless. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

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