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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Jan 1, 2025 | 2:50 PM IST
Hepagrit-25000 Injection 5 ml is used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks. It contains Heparin, which works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation. Some people may experience haemorrhage (bleeding), thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

HEPARIN-5000IU

Manufacturer/Marketer :

Integrity Pharmaceutical Corp

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Hepagrit-25000 Injection 5 ml

Hepagrit-25000 Injection 5 ml belongs to a class of drugs called anticoagulants or blood thinners. Hepagrit-25000 Injection 5 ml is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks. Deep vein thrombosis is a medical condition in which blood clots form in deep veins, usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs. A stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death. Transient ischaemic attack (TIA) is a condition also called mini-strokes. These have similar symptoms to a stroke, but the effects usually last less than 24 hours. Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death.

Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs. Hepagrit-25000 Injection 5 ml works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation.

Hepagrit-25000 Injection 5 ml will be administered by a healthcare professional; do not self-administer. Some people may experience haemorrhage, thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Most of these side effects of Hepagrit-25000 Injection 5 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Hepagrit-25000 Injection 5 ml or any other medicines, please tell your doctor. It is not known whether Hepagrit-25000 Injection 5 ml harms the baby or passes into breast milk in pregnancy and breastfeeding state. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Hepagrit-25000 Injection 5 ml. Hepagrit-25000 Injection 5 ml is not recommended for children below 2 months of age. If you have diabetes, kidney or liver problems, bleeding problems, or are aged above 60 years, inform your doctor before taking Hepagrit-25000 Injection 5 ml.

Uses of Hepagrit-25000 Injection 5 ml

Prevention of blood clots.

Medicinal Benefits

Hepagrit-25000 Injection 5 ml is primarily used to prevent and treat blood clots by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). Hepagrit-25000 Injection 5 ml also reduces the risk of blood clots during surgeries (like heart surgery). Hepagrit-25000 Injection 5 ml is used as an anticoagulant in blood transfusion and in a dialysis procedure.

Side Effects of Hepagrit-25000 Injection 5 ml

  • Red itchy patches or lumps at the site of injection
  • Unusual bleeding
  • Skin redness

Directions for Use

Hepagrit-25000 Injection 5 ml will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Use Hepagrit-25000 Injection 5 ml cautiously in conditions with increased risk of bleeding. Use of name contraindicated in patients with HIT - Heparin-induced thrombosis (the abnormal formation of blood clots inside a blood vessel) and HITT (heparin-induced thrombocytopenia and thrombosis) might occur. Monitoring of blood coagulation tests like platelet count and haematocrit should be done in all patients receiving Hepagrit-25000 Injection 5 ml. Patients should inform the doctor that they are receiving Hepagrit-25000 Injection 5 ml before any surgery is scheduled.

Therapeutic Class

ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS

Drug-Drug Interactions

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HeparinAlteplase
Critical
HeparinMifepristone
Critical

Drug-Food Interactions

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HEPARIN-5000IUHerbal products/medicines
Moderate

Habit Forming

No

How Hepagrit-25000 Injection 5 ml Works

Hepagrit-25000 Injection 5 ml works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation.

What if I have taken an overdose of Hepagrit-25000 Injection 5 ml

The overdose of Hepagrit-25000 Injection 5 ml is unlikely as it is administered by a doctor. Too much heparin may cause bleeding. Therefore, if you suspect any adverse reactions or unusual symptoms or more severe bleeding while on treatment with Hepagrit-25000 Injection 5 ml, please inform your doctor immediately.
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Alcohol

Caution

You are recommended to avoid consumption of alcohol with Hepagrit-25000 Injection 5 ml as it may cause severe bleeding in the stomach and harmful side effects to the liver.

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Pregnancy

Caution

Hepagrit-25000 Injection 5 ml is a Category C pregnancy drug and should be given to pregnant women only if clearly needed and has more benefits than risks. Preservative-free forms are preferred in pregnant women as preservatives such as benzyl alcohol may cross the placenta.

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Breast Feeding

Caution

Hepagrit-25000 Injection 5 ml should be given to breastfeeding mothers only if clearly needed and has more benefits than risks.

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Driving

Safe if prescribed

Hepagrit-25000 Injection 5 ml usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Hepagrit-25000 Injection 5 ml should be given with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Hepagrit-25000 Injection 5 ml should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Hepagrit-25000 Injection 5 ml is not recommended for children below 2 months.

Country of origin

India

Manufacturer/Marketer address

1172, Opposite Railway Station, Nr By Bajwa Railway Crossing Line, Bajwa, Vadodara
Other Info - HEP0387

Author Details

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FAQs

Hepagrit-25000 Injection 5 ml is used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks.
Hepagrit-25000 Injection 5 ml works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). Thereby, preventing blood clot formation.
No, you are not recommended to take ibuprofen with Hepagrit-25000 Injection 5 ml as co-administration of these two medicines may increase the risk of bleeding more easily. However, please consult a doctor before taking other medicines with Hepagrit-25000 Injection 5 ml.
Yes, Hepagrit-25000 Injection 5 ml may increase potassium levels in the blood (hyperkalaemia), especially when given for a long period. Therefore, it is advised to inform your doctor if you are taking any medicines that increase potassium levels in the blood.
Yes, Hepagrit-25000 Injection 5 ml may cause bleeding. If you notice purple spots on the skin or unusual bruising, blood in urine, black tarry stools, unusual bleeding from gums or nose, please inform your doctor immediately as these are signs of bleeding more easily.
Yes, Hepagrit-25000 Injection 5 ml may cause allergic reactions such as fever, chills, difficulty in breathing, wheezing, blue shade to the lips, swelling of lips, and eyes. It is not necessary for everyone taking Hepagrit-25000 Injection 5 ml to experience an allergic reaction. However, if you notice any of these signs, please inform your doctor immediately.

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