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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Celhep 25000/5ml Injection is used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks. It contains Heparin, which works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation. Some people may experience haemorrhage (bleeding), thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

HEPARIN-5000IU

Manufacturer/Marketer :

Celon Laboratories Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Celhep 25000/5ml Injection

Celhep 25000/5ml Injection belongs to a class of drugs called anticoagulants or blood thinners. Celhep 25000/5ml Injection is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks. Deep vein thrombosis is a medical condition in which blood clots form in deep veins, usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs. A stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death. Transient ischaemic attack (TIA) is a condition also called mini-strokes. These have similar symptoms to a stroke, but the effects usually last less than 24 hours. Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death.

Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs. Celhep 25000/5ml Injection works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation.

Celhep 25000/5ml Injection will be administered by a healthcare professional; do not self-administer. Some people may experience haemorrhage, thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Most of these side effects of Celhep 25000/5ml Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Celhep 25000/5ml Injection or any other medicines, please tell your doctor. It is not known whether Celhep 25000/5ml Injection harms the baby or passes into breast milk in pregnancy and breastfeeding state. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Celhep 25000/5ml Injection. Celhep 25000/5ml Injection is not recommended for children below 2 months of age. If you have diabetes, kidney or liver problems, bleeding problems, or are aged above 60 years, inform your doctor before taking Celhep 25000/5ml Injection.

Uses of Celhep 25000/5ml Injection

Prevention of blood clots.

Directions for Use

Celhep 25000/5ml Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Celhep 25000/5ml Injection is primarily used to prevent and treat blood clots by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). Celhep 25000/5ml Injection also reduces the risk of blood clots during surgeries (like heart surgery). Celhep 25000/5ml Injection is used as an anticoagulant in blood transfusion and in a dialysis procedure.

How Celhep 25000/5ml Injection Works

Celhep 25000/5ml Injection works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Celhep 25000/5ml Injection

  • Red itchy patches or lumps at the site of injection
  • Unusual bleeding
  • Skin redness

What if I have taken an overdose of Celhep 25000/5ml Injection

The overdose of Celhep 25000/5ml Injection is unlikely as it is administered by a doctor. Too much heparin may cause bleeding. Therefore, if you suspect any adverse reactions or unusual symptoms or more severe bleeding while on treatment with Celhep 25000/5ml Injection, please inform your doctor immediately.

Drug Warnings

Use Celhep 25000/5ml Injection cautiously in conditions with increased risk of bleeding. Use of name contraindicated in patients with HIT - Heparin-induced thrombosis (the abnormal formation of blood clots inside a blood vessel) and HITT (heparin-induced thrombocytopenia and thrombosis) might occur. Monitoring of blood coagulation tests like platelet count and haematocrit should be done in all patients receiving Celhep 25000/5ml Injection. Patients should inform the doctor that they are receiving Celhep 25000/5ml Injection before any surgery is scheduled.

Drug-Drug Interactions

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HeparinBazedoxifene
Critical
HeparinAlteplase
Critical

Drug-Drug Interactions

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HeparinBazedoxifene
Critical
How does the drug interact with Celhep 25000/5ml Injection:
When Celhep 25000/5ml Injection is taken with bazedoxifene the effects of Celhep 25000/5ml Injection are reduced by bazedoxifene.

How to manage the interaction:
Taking Bazedoxifene with Celhep 25000/5ml Injection is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinAlteplase
Critical
How does the drug interact with Celhep 25000/5ml Injection:
Taking Alteplase with Celhep 25000/5ml Injection can increase the risk of bleeding.

How to manage the interaction:
Taking Celhep 25000/5ml Injection with Alteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
HeparinTiclopidine
Critical
How does the drug interact with Celhep 25000/5ml Injection:
Taking Ticlopidine with Celhep 25000/5ml Injection can increase the risk of bleeding.

How to manage the interaction:
Taking Ticlopidine with Celhep 25000/5ml Injection is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinTenecteplase
Critical
How does the drug interact with Celhep 25000/5ml Injection:
Taking Tenecteplase with Celhep 25000/5ml Injection can increase the risk of bleeding.

How to manage the interaction:
Taking Celhep 25000/5ml Injection with Tenecteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
HeparinOritavancin
Critical
How does the drug interact with Celhep 25000/5ml Injection:
Using Celhep 25000/5ml Injection with Oritavancin can make Celhep 25000/5ml Injection less effective as a therapy.

How to manage the interaction:
Celhep 25000/5ml Injection is not recommended within 120 hours (5 days) of taking oritavancin. Oritavancin can interfere with certain of the major coagulation tests used to assess Celhep 25000/5ml Injection's effectiveness and safety, it can be taken only if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
HeparinMifepristone
Critical
How does the drug interact with Celhep 25000/5ml Injection:
Taking Mifepristone with Celhep 25000/5ml Injection can increase the risk of negative side effects.

How to manage the interaction:
Taking Celhep 25000/5ml Injection with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinOmacetaxine mepesuccinate
Severe
How does the drug interact with Celhep 25000/5ml Injection:
Taking Celhep 25000/5ml Injection with Omacetaxine mepesuccinate can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Omacetaxine mepesuccinate with Celhep 25000/5ml Injection can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness, consult a doctor. Do not discontinue any medications without consulting a doctor.
HeparinProtamine
Severe
How does the drug interact with Celhep 25000/5ml Injection:
When Protamine and Celhep 25000/5ml Injection are used together, can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Protamine and Celhep 25000/5ml Injection, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
HeparinAbciximab
Severe
How does the drug interact with Celhep 25000/5ml Injection:
Taking Abciximab with Celhep 25000/5ml Injection may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Abciximab with Celhep 25000/5ml Injection can result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any of these signs - bleeding, bruising, vomiting, headache, dizziness, weakness, or blood in your urine or stools, it's important to contact a doctor immediately. Do not stop using any medications without talking to a doctor.
HeparinEdoxaban
Severe
How does the drug interact with Celhep 25000/5ml Injection:
Taking Edoxaban with Celhep 25000/5ml Injection may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Celhep 25000/5ml Injection with Edoxaban can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS

Celhep 25000/5ml Injection Substitute

Substitutes safety advice
  • Heparin 5000IU Injection 5 ml

    by AYUR

    20.70per tablet
  • HEP 5 Injection 5 ml

    21.24per tablet
  • Heparen 5000IU Injection 5 ml

    61.02per tablet
  • Reniparin 5000IU Injection 1's

    122.40per tablet
  • Celhep 5000 IU Injection 5 ml

    21.34per tablet
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Alcohol

Caution

You are recommended to avoid consumption of alcohol with Celhep 25000/5ml Injection as it may cause severe bleeding in the stomach and harmful side effects to the liver.

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Pregnancy

Caution

Celhep 25000/5ml Injection is a Category C pregnancy drug and should be given to pregnant women only if clearly needed and has more benefits than risks. Preservative-free forms are preferred in pregnant women as preservatives such as benzyl alcohol may cross the placenta.

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Breast Feeding

Caution

Celhep 25000/5ml Injection should be given to breastfeeding mothers only if clearly needed and has more benefits than risks.

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Driving

Safe if prescribed

Celhep 25000/5ml Injection usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Celhep 25000/5ml Injection should be given with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Celhep 25000/5ml Injection should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Celhep 25000/5ml Injection is not recommended for children below 2 months.

FAQs

Celhep 25000/5ml Injection is used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks.
Celhep 25000/5ml Injection works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). Thereby, preventing blood clot formation.
No, you are not recommended to take ibuprofen with Celhep 25000/5ml Injection as co-administration of these two medicines may increase the risk of bleeding more easily. However, please consult a doctor before taking other medicines with Celhep 25000/5ml Injection.
Yes, Celhep 25000/5ml Injection may increase potassium levels in the blood (hyperkalaemia), especially when given for a long period. Therefore, it is advised to inform your doctor if you are taking any medicines that increase potassium levels in the blood.
Yes, Celhep 25000/5ml Injection may cause bleeding. If you notice purple spots on the skin or unusual bruising, blood in urine, black tarry stools, unusual bleeding from gums or nose, please inform your doctor immediately as these are signs of bleeding more easily.
Yes, Celhep 25000/5ml Injection may cause allergic reactions such as fever, chills, difficulty in breathing, wheezing, blue shade to the lips, swelling of lips, and eyes. It is not necessary for everyone taking Celhep 25000/5ml Injection to experience an allergic reaction. However, if you notice any of these signs, please inform your doctor immediately.

Country of origin

INDIA

Manufacturer/Marketer address

Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081
Other Info - CEL0298

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