Gramogyl Plus Tablet belongs to the group of medicines called antibiotics used to treat diarrhoea and dysentery of bacterial, amoebic or mixed origins. Diarrhoea is a condition which is characterized by loose and watery stools. Dysentery is an inflammation of intestines accompanied by bloody diarrhoea.
 
Gramogyl Plus Tablet is a combination of three drugs, namely: Norfloxacin, Tinidazole, and Lactobacillus. Norfloxacin prevents the bacteria from repairing and reproducing themselves. Tinidazole kills the bacteria by damaging their DNA. Lactobacillus helps balance the number of beneficial bacteria in the digestive tract (gut) to manage water loss (diarrhoea) due to antibiotics or infections. 
 
You can take Gramogyl Plus Tablet with or without food. Swallow Gramogyl Plus Tablet as a whole; do not crush or chew it. In some cases, Gramogyl Plus Tablet may cause certain common side-effects such as abdominal cramps, nausea, headache, dry mouth, and dizziness. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Consult your doctor if you experience pain in tendons, swelling, and inflammation as Gramogyl Plus Tablet is associated with an increased risk of tendon rupture and tendonitis. Maintain a minimum gap of two hours between Gramogyl Plus Tablet and antacid, vitamin and mineral medicines containing zinc and iron. Consult your doctor if you are pregnant or breastfeeding. Gramogyl Plus Tablet may cause dizziness and vision problems, so be cautious while driving. 

Gramogyl Plus Tablet belongs to the group of medicines called antibiotics used to treat diarrhoea and dysentery of bacterial, amoebic or mixed origins. Gramogyl Plus Tablet is a combination of three drugs, namely: Norfloxacin, Tinidazole, and Lactobacillus. Norfloxacin prevents the bacteria from repairing and reproducing themselves. Tinidazole kills bacteria by damaging their DNA. Due to antibiotic intake, a large amount of beneficial bacteria gets destroyed, so Lactobacillus helps in balancing the number of beneficial bacteria in the digestive tract (gut) to manage water loss (diarrhoea) due to antibiotics or infections. Lactobacillus also helps in the treatment of diarrhoea (water loss) and cramps caused due to harmful E. Coli bacteria. Gramogyl Plus Tablet is a broad-spectrum antibiotic which is effective against a wide range of gram-positive and gram-negative bacteria.

• Abdominal cramps
• Nausea
• Headache
• Dry mouth
• Dizziness

Do not take Gramogyl Plus Tablet if you are allergic to any of its contents; if you had swelling or tearing of tendons while taking quinolone antibiotics. Gramogyl Plus Tablet is associated with an increased risk of tendon rupture and tendonitis. Consult your doctor immediately if you experience tendon pain, swelling or inflammation while taking Gramogyl Plus Tablet. Do not take Gramogyl Plus Tablet if you have myasthenia gravis as it may cause increased muscle weakness. Talk to your doctor before taking Gramogyl Plus Tablet if you have/had blood dyscrasia, peripheral neuropathy, heart, liver or kidney problems. Maintain a minimum gap of two hours between Gramogyl Plus Tablet and antacid, vitamin and mineral medicines containing zinc and iron. Do not take Gramogyl Plus Tablet if you are pregnant or breastfeeding. Avoid alcohol consumption while taking Gramogyl Plus Tablet as it causes increased dizziness. Gramogyl Plus Tablet may cause dizziness and vision problems, so be cautious while driving. 

Drug-Drug Interactions: Gramogyl Plus Tablet may interact with pain killers (aspirin, ibuprofen), anti-coagulant/blood thinner (warfarin), anti-gout (probenecid), antibiotic (azithromycin, sulfamethoxazole, trimethoprim, metronidazole, nitrofurantoin, erythromycin), and calcium supplements (calcium/vitamin D).

Drug-Food Interactions:  Avoid consuming caffeine products along with Gramogyl Plus Tablet as it might increase the effects of caffeine.

Drug-Disease Interaction: Inform your doctor if you have colitis (inflammation in the lining of the colon), tendonitis (inflammation in tendons), CNS disorders, myasthenia gravis (neuromuscular disease), peripheral neuropathy (nerve pain), neurological toxicity, alcoholism, blood dyscrasia, crystalluria (cloudy urine), diabetes, kidney, liver and heart problems.

• ASPIRIN
• IBUPROFEN
• WARFARIN
• PROBENECID
• AZITHROMYCIN
• SULFAMETHOXAZOLE
• TRIMETHOPRIM
• METRONIDAZOLE
• NITROFURANTOIN
• ERYTHROMYCIN
• CALCIUM CARBONATE+CHOLECALCIFEROL

• Antibiotics can alter the useful bacteria in the stomach, which help indigestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.

• Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.

• Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.

• Avoid consumption of alcohol and usage of tobacco.

• Gramogyl Plus Tablet may cause changes in liver function tests and prothrombin time (time taken for blood clotting). Inform the person doing the tests that you are taking Gramogyl Plus Tablet.

Diarrhoea: It is a condition which is characterized by loose and watery stools with a frequent need to have a bowel movement. Diarrhoea might be a result of bacterial or viral infection. It can be acute (lasts for a few days) or chronic (lasts for a few weeks). The common causes of diarrhoea include food intolerance, food allergy, adverse reactions to a medication, or infections. Symptoms include nausea, abdominal pain, cramps, bloating, dehydration, watery loose stools, and frequent urge to evacuate the bowels.

Dysentery: It is an inflammation of the intestines accompanied by bloody diarrhoea. Sometimes, mucus may be found in stools. Dysentery usually lasts for 3-7 days. Dysentery usually occurs due to poor hygiene, improper sanitization, and contaminated food or water. Symptoms include abdominal cramps, nausea, vomiting, fever, and dehydration.