apollo
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:40 PM IST
Glipol Tablet is used to treat type-2 diabetes. It contains Glibenclamide, which acts by increasing the amount of insulin released by the pancreas. It stimulates insulin secretion from the pancreas and decreases blood sugar levels. In a nutshell, it prevents blood glucose levels from rising to very high levels, thus keeping your diabetes under control. It shows optimum effects when taken along with healthy lifestyle changes like weight loss, regular exercise, a healthy diet, etc. A common side effect of this medicine is low blood glucose levels characterized by dizziness, sweating, palpitations, hunger pangs, dry mouth, skin, etc. To avoid hypoglycaemia, you should not miss meals and should carry some form of sugar along with you. Other side effects include taste change, nausea, diarrhoea, stomach pain, headache, and upper respiratory symptoms.
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Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Glipol Tablet

Glipol Tablet is used to treat type-2 diabetes. Type 2 diabetes is a chronic or lifelong condition affecting how your body processes glucose. People with type 2 diabetes either do not produce enough insulin, or if the insulin is produced, it cannot perform its function in the body (insulin resistance). Thus, the blood glucose level increases and symptoms such as frequent urination increased thirst and increased hunger.

Glipol Tablet contains Glibenclamide, which acts by increasing the amount of insulin released by the pancreas. It stimulates insulin secretion from the pancreas and decreases blood sugar levels. In a nutshell, it prevents blood glucose levels from rising to very high levels, thus keeping your diabetes under control. Glipol Tablet shows optimum effects when taken along with healthy lifestyle changes like weight loss, regular exercise, a healthy diet, etc.

Glipol Tablet should be taken with food to avoid an upset stomach .Glipol Tablet should be taken at the same time of the day each time for the best results. Your doctor will decide what dose should be taken for better advice, and it can change timely depending upon your condition. A common side effect of Glipol Tablet is low blood glucose levels characterized by dizziness, sweating, palpitations, hunger pangs, dry mouth, skin, etc. To avoid hypoglycaemia, you should not miss meals and should carry some form of sugar along with you. Other side effects include taste change, nausea, diarrhoea, stomach pain, headache, and upper respiratory symptoms.

Glipol Tablet should not be stopped even if you feel better without consulting your doctor as the sugar levels change. If you stop taking Glipol Tablet abruptly, it may increase your sugar levels, which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy) and nerve damage (neuropathy). Glipol Tablet should not be taken if you have severe kidney or liver disease or have a diabetic coma. Please inform your doctor if you have had liver, kidney or heart disease, are pregnant or planning to get pregnant, are breastfeeding, or have a blood disease called G6PD-deficiency anaemia or heart disease. Mental alertness may be altered due to low or high blood sugar when Glipol Tablet is not taken regularly, which may affect your ability to drive or operate machinery.

Uses of Glipol Tablet

Treatment of Type-2 diabetes mellitus.

Medicinal Benefits

Glipol Tablet contains Glibenclamide, a 'sulfonylurea', which decreases raised blood sugar levels by stimulating insulin release from the beta cells located in the pancreas (insulin-secreting organ). In a nutshell, it prevents the blood glucose levels from rising to very high levels, thus keeping your diabetes under control. Glipol Tablet shows optimum effects when taken along with healthy lifestyle changes like weight loss, regular exercise, healthy diet, etc.

Directions for Use

Swallow Glipol Tablet as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Glipol Tablet

  • Low blood sugar (hypoglycaemia)
  • Nausea
  • Heartburn
  • Feeling of fullness
  • Vomiting
  • Diarrhoea
  • Abdominal pain
  • Weight gain

Drug Warnings

Some diabetic patients taking Glipol Tablet may develop a rare but serious condition called lactic acidosis. In this condition, there is too much lactic acid accumulated in the blood. So, your liver and kidney proper functioning is required to eliminate excess lactic acid from the blood. If you are allergic (hypersensitive) to Glibenclamide or any ingredient of Glipol Tablet, have severe liver or kidney problems, have severe thyroid or adrenal gland problems, have ever had a diabetic coma, Glipol Tablet should not be taken. Consult your doctor and take only if prescribed under medical supervision. Glipol Tablet shows optimum effects when taken along with healthy lifestyle changes like weight loss, regular exercise, healthy diet, etc. 

Drug Interactions

Drug-Drug Interactions: Glipol Tablet may interact with pain killers (aspirin, phenylbutazone), blood thinners (heparin), cholesterol-lowering agents (clofibrate), anti-depressants (nortriptyline), anti-hypertensives (captopril, enalapril), stomach ulcers medicines (cimetidine, ranitidine). So, tell your doctor if you are using these drugs before taking Glipol Tablet.

Drug-Food Interactions: Taking Glipol Tablet with alcoholic beverages may increase the risk of hypoglycemia (low blood sugar).

Drug-Disease Interactions: Glipol Tablet should be avoided in patients with severe liver or kidney problems, severe thyroid or adrenal gland problems, or whoever had a diabetic coma as it may worsen the condition.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • HEPARIN
  • ENALAPRIL
  • CIMETIDINE
  • RANITIDINE
  • PHENYLBUTAZONE
  • CLOFIBRATE
  • NORTRIPTYLINE
  • CAPTOPRIL

Habit Forming

No

Diet & Lifestyle Advise

  • Fill your half plate with starchy veggies, a quarter with proteins and a quarter with whole grain.
  • Eat at regular intervals. Do not take a long gap between a meal or snack.
  • Monitor your blood sugar level regularly, especially when there are a lot of fluctuations.
  • Invest at least 150 min of moderate-intensity physical activity and 15 minutes of high-intensity exercise every week.
  • Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replace refined carbohydrates containing whole-grain foods and increase intake of fruits and veggies and other fiber-enriched foods.
  • Reduce intake of saturated fat (or hidden fats) in food like chips, crisps, pastries, biscuits, and samosas. Choose omega 3 fatty acid-containing oils for daily cooking. You may use palm oil, mustard oil, groundnut oil, rice bran oil and safflower oil for frying.
  • Do not take stress as it may elevate your blood sugar level. You may adopt stress management techniques like mindfulness, yoga, or meditation to control stress-related blood sugar changes.
  • Opt for low-fat dairy products (low-fat yogurt, fat-free milk, and cheese, etc.).
  • Keep your blood pressure as normal (120/80) as possible as it reduces the risk of cardiovascular diseases in diabetes patients.

Special Advise

  • Your doctor may advise regular liver function tests to look for symptoms of any liver problems.

  • Inform your doctor about the use of Glipol Tablet before any surgery, and the doctor may advise insulin before surgery.

Disease/Condition Glossary

Diabetes Mellitus type 2: It is a condition in which either the body stops producing enough insulin (the hormone which helps to decrease sugar levels in the blood) or is resistant to insulin action. As a result, excessive insulin is produced. Still, it fails to act on the organs of the body. Type 2 diabetes symptoms include feeling exhausted all the time, feeling thirsty, having blurry vision, and the urge to urinate (pee) more often. Complications of type 2 diabetes include skin infection, eye problems (retinopathy), nerve damage (neuropathy), diabetic foot (foot ulcer), kidney disease (nephropathy), high blood pressure and even stroke. Both low and high blood sugar levels can be dangerous and should be treated as soon as possible. Your HbA1c below 5.7% is normal, 5.7-6.4% confirms the prediabetes stage and 6.5% or greater states diabetes condition.

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Alcohol

Unsafe

Glipol Tablet should not be taken until prescribed if you are taking alcohol. Taking Glipol Tablet with alcohol can cause hypoglycemia. So, keep your doctor informed if you drink alcohol.

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Pregnancy

Caution

As the data around the use of Glipol Tablet in pregnant women is limited, the use of Glipol Tablet in pregnancy is restricted.It is highly recommended to consult your doctor before taking this drug in case you are pregnant.

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Breast Feeding

Caution

Tell your doctor if you are breastfeeding. Do not breastfeed while you are taking Glipol Tablet without advice from your doctor.

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Driving

Caution

Glipol Tablet may cause hypoglycemia (low blood sugar levels) whose symptoms include unusual sleepiness, shivering, palpitations, sweating, etc. This may affect your ability to drive. Use caution while driving or doing anything that requires concentration or mental alertness.

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Liver

Caution

Glipol Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor, depending on your liver function tests.

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Kidney

Unsafe

Glipol Tablet is unsafe, especially if you have a history of kidney diseases/conditions.

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Children

Unsafe

Glipol Tablet is not recommended for children below the age of 18 years. The safety and effectiveness of Glipol Tablet have not been established in children due to limited evidence. So, only take Glipol Tablet if the doctor has prescribed you.

Country of origin

India

Manufacturer/Marketer address

5, Cubit House, 13/369, Panchratna Estate, B/H Ankoor Oil Factory, Opp. Bhagyoday Hotel, Changodar, Ahmedabad-382210 (Guj.) India.
Other Info - GL36609

Author Details

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FAQs

Glipol Tablet is used to treat type-2 diabetes, a chronic or lifelong condition affecting how the body processes glucose.
Glipol Tablet contains Glibenclamide, which increases the amount of insulin released by the pancreas. It stimulates insulin secretion from the pancreas and decreases blood sugar levels. In a nutshell, it prevents blood glucose levels from rising to very high levels, thus keeping your diabetes under control.
Yes, Glipol Tablet can cause constipation. Eat a proper well-balanced diet and drink plenty of fluid to avoid it.
Yes, Glipol Tablet is known to cause an upset stomach if taken empty stomach. So, it should be preferably taken with a meal or just after a meal to avoid an upset stomach.
No, Glipol Tablet is only prescribed for the treatment for the type 2 diabetes along with a healthy diet and lifestyle. It should not be taken for the treatment of type 1 diabetes.
Hypoglycemia refers to low blood sugar levels. The symptoms of hypoglycemia (low blood sugar) include sweating, feeling shaky or anxious, looking pale, feeling hungry, feeling dizzy, and feeling that your heart is pounding (palpitations). Glipol Tablet can cause hypoglycemia. Hypoglycemia can occur if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with Glipol Tablet. People with diabetes are advised to keep a quick sugar source like glucose tablets, honey or fruit juice.

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