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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Daonil Tablet is used to treat type-2 diabetes. It contains Glibenclamide, which acts by increasing the amount of insulin released by the pancreas. It stimulates insulin secretion from the pancreas and decreases blood sugar levels. In a nutshell, it prevents blood glucose levels from rising to very high levels, thus keeping your diabetes under control. It shows optimum effects when taken along with healthy lifestyle changes like weight loss, regular exercise, a healthy diet, etc. A common side effect of this medicine is low blood glucose levels characterized by dizziness, sweating, palpitations, hunger pangs, dry mouth, skin, etc. To avoid hypoglycaemia, you should not miss meals and should carry some form of sugar along with you. Other side effects include taste change, nausea, diarrhoea, stomach pain, headache, and upper respiratory symptoms.
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Composition :

GLIBENCLAMIDE-5MG

Manufacturer/Marketer :

Sanofi India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Daonil Tablet

Daonil Tablet is used to treat type-2 diabetes. Type 2 diabetes is a chronic or lifelong condition affecting how your body processes glucose. People with type 2 diabetes either do not produce enough insulin, or if the insulin is produced, it cannot perform its function in the body (insulin resistance). Thus, the blood glucose level increases and symptoms such as frequent urination increased thirst and increased hunger.

Daonil Tablet contains Glibenclamide, which acts by increasing the amount of insulin released by the pancreas. It stimulates insulin secretion from the pancreas and decreases blood sugar levels. In a nutshell, it prevents blood glucose levels from rising to very high levels, thus keeping your diabetes under control. Daonil Tablet shows optimum effects when taken along with healthy lifestyle changes like weight loss, regular exercise, a healthy diet, etc.

Daonil Tablet should be taken with food to avoid an upset stomach .Daonil Tablet should be taken at the same time of the day each time for the best results. Your doctor will decide what dose should be taken for better advice, and it can change timely depending upon your condition. A common side effect of Daonil Tablet is low blood glucose levels characterized by dizziness, sweating, palpitations, hunger pangs, dry mouth, skin, etc. To avoid hypoglycaemia, you should not miss meals and should carry some form of sugar along with you. Other side effects include taste change, nausea, diarrhoea, stomach pain, headache, and upper respiratory symptoms.

Daonil Tablet should not be stopped even if you feel better without consulting your doctor as the sugar levels change. If you stop taking Daonil Tablet abruptly, it may increase your sugar levels, which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy) and nerve damage (neuropathy). Daonil Tablet should not be taken if you have severe kidney or liver disease or have a diabetic coma. Please inform your doctor if you have had liver, kidney or heart disease, are pregnant or planning to get pregnant, are breastfeeding, or have a blood disease called G6PD-deficiency anaemia or heart disease. Mental alertness may be altered due to low or high blood sugar when Daonil Tablet is not taken regularly, which may affect your ability to drive or operate machinery.

Uses of Daonil Tablet

Treatment of Type-2 diabetes mellitus.

Directions for Use

Swallow Daonil Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Daonil Tablet contains Glibenclamide, a 'sulfonylurea', which decreases raised blood sugar levels by stimulating insulin release from the beta cells located in the pancreas (insulin-secreting organ). In a nutshell, it prevents the blood glucose levels from rising to very high levels, thus keeping your diabetes under control. Daonil Tablet shows optimum effects when taken along with healthy lifestyle changes like weight loss, regular exercise, healthy diet, etc.

How Daonil Tablet Works

Daonil Tablet contains Glibenclamide, which acts by increasing the amount of insulin released by the pancreas. It stimulates insulin secretion from the pancreas and decreases blood sugar levels. In a nutshell, it prevents blood glucose levels from rising to very high levels, thus keeping your diabetes under control. Daonil Tablet shows optimum effects when taken along with healthy lifestyle changes like weight loss, regular exercise, a healthy diet, etc.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Daonil Tablet

  • Low blood sugar (hypoglycaemia)
  • Nausea
  • Heartburn
  • Feeling of fullness
  • Vomiting
  • Diarrhoea
  • Abdominal pain
  • Weight gain

What if I have taken an overdose of Daonil Tablet

Do not take more than the prescribed dose of Daonil Tablet as it may cause overdose resulting in severe low blood sugar. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Some diabetic patients taking Daonil Tablet  may develop a rare but serious condition called lactic acidosis. In this condition, there is too much lactic acid accumulated in the blood. So, your liver and kidney proper functioning is required to eliminate excess lactic acid from the blood. If you are allergic (hypersensitive) to Glibenclamide or any ingredient of Daonil Tablet , have severe liver or kidney problems, have severe thyroid or adrenal gland problems, have ever had a diabetic coma, Daonil Tablet should not be taken. Consult your doctor and take only if prescribed under medical supervision. Daonil Tablet shows optimum effects when taken along with healthy lifestyle changes like weight loss, regular exercise, healthy diet, etc. 

Drug-Drug Interactions

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GlibenclamideOfloxacin
Severe
GlibenclamideCinoxacin
Severe

Drug-Drug Interactions

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GlibenclamideOfloxacin
Severe
How does the drug interact with Daonil Tablet:
Co-administration of Ofloxacin with Daonil Tablet can sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Daonil Tablet can be taken with Ofloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat or symptoms of high blood sugar such as increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
GlibenclamideCinoxacin
Severe
How does the drug interact with Daonil Tablet:
Co-administration of Daonil Tablet with Cinoxacin can sometimes affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.

How to manage the interaction:
Co-administration of Daonil Tablet with Cinoxacin can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your urination and if you notice any changes, let your doctor know. If you experience any of these symptoms - high or low blood sugar, severe infections, headaches, dizziness, confusion, or feeling shaky, make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
GlibenclamideEnoxacin
Severe
How does the drug interact with Daonil Tablet:
When Daonil Tablet is taken with Enoxacin, it may affect the blood glucose levels which may leads to hypoglycemia or hyperglycemia.

How to manage the interaction:
There may be a possibility of interaction between Daonil Tablet and Enoxacin, but it can be taken if prescribed by a doctor. If you notice any symptoms like headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat, increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.
GlibenclamideMiconazole
Severe
How does the drug interact with Daonil Tablet:
Co-administration of Miconazole with Daonil Tablet may increase the blood levels and effects of Daonil Tablet leading to low blood glucose levels.

How to manage the interaction:
Although there is a possible interaction, Daonil Tablet can be taken with miconazole if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
GlibenclamideLevofloxacin
Severe
How does the drug interact with Daonil Tablet:
Co-administration of Levofloxacin with Daonil Tablet may affect blood glucose levels.

How to manage the interaction:
Although there is a possible interaction, Daonil Tablet can be taken with levofloxacin if prescribed by the doctor. Consult the prescriber if you experience nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, pulse, rapid heartbeat, increased urination, increased thirst, and increased hunger. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
GlibenclamideLomefloxacin
Severe
How does the drug interact with Daonil Tablet:
Co-administration of Lomefloxacin may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Daonil Tablet can be taken with lomefloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat or symptoms of high blood sugar such as increased urination, increased thirst, and increased hunger. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
GlibenclamideSparfloxacin
Severe
How does the drug interact with Daonil Tablet:
Co-administration of Sparfloxacin can sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Daonil Tablet can be taken with sparfloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat or symptoms of high blood sugar such as increased urination, increased thirst, and increased hunger. Do not discontinue the medications without consulting a doctor.
GlibenclamideNorfloxacin
Severe
How does the drug interact with Daonil Tablet:
Co-administration of Norfloxacin with Daonil Tablet may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Daonil Tablet can be taken with Norfloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat or symptoms of high blood sugar such as increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue any medications without consulting a doctor.
GlibenclamideMoxifloxacin
Severe
How does the drug interact with Daonil Tablet:
Co-administration of Moxifloxacin may affect blood glucose levels. Both high blood glucose and low blood glucose.

How to manage the interaction:
Although there is a possible interaction, Daonil Tablet can be taken with Moxifloxacin if prescribed by the doctor. Consult the prescriber if you experience headache, dizziness, rapid heartbeat, increased urination, increased thirst, and increased hunger. Do not discontinue the medications without consulting a doctor.
GlibenclamideGrepafloxacin
Severe
How does the drug interact with Daonil Tablet:
Co-administration of Daonil Tablet with Grepafloxacin can sometimes affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.

How to manage the interaction:
Co-administration of Daonil Tablet with Grepafloxacin can possibly result in an interaction, but it can be taken if a doctor has advised it. If you experience any of these symptoms - severe infections, headaches, dizziness, drowsiness, confusion, trembling, nausea, hunger, weakness, fast heartbeat, or excessive thirst - it's best to call a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Fill your half plate with starchy veggies, a quarter with proteins and a quarter with whole grain.
  • Eat at regular intervals. Do not take a long gap between a meal or snack.
  • Monitor your blood sugar level regularly, especially when there are a lot of fluctuations.
  • Invest at least 150 min of moderate-intensity physical activity and 15 minutes of high-intensity exercise every week.
  • Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replace refined carbohydrates containing whole-grain foods and increase intake of fruits and veggies and other fiber-enriched foods.
  • Reduce intake of saturated fat (or hidden fats) in food like chips, crisps, pastries, biscuits, and samosas. Choose omega 3 fatty acid-containing oils for daily cooking. You may use palm oil, mustard oil, groundnut oil, rice bran oil and safflower oil for frying.
  • Do not take stress as it may elevate your blood sugar level. You may adopt stress management techniques like mindfulness, yoga, or meditation to control stress-related blood sugar changes.
  • Opt for low-fat dairy products (low-fat yogurt, fat-free milk, and cheese, etc.).
  • Keep your blood pressure as normal (120/80) as possible as it reduces the risk of cardiovascular diseases in diabetes patients.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

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Alcohol

Unsafe

Daonil Tablet should not be taken until prescribed if you are taking alcohol. Taking Daonil Tablet with alcohol can cause hypoglycemia. So, keep your doctor informed if you drink alcohol.

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Pregnancy

Caution

As the data around the use of Daonil Tablet in pregnant women is limited, the use of Daonil Tablet in pregnancy is restricted.It is highly recommended to consult your doctor before taking this drug in case you are pregnant.

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Breast Feeding

Caution

Tell your doctor if you are breastfeeding. Do not breastfeed while you are taking Daonil Tablet without advice from your doctor.

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Driving

Caution

Daonil Tablet may cause hypoglycemia (low blood sugar levels) whose symptoms include unusual sleepiness, shivering, palpitations, sweating, etc. This may affect your ability to drive. Use caution while driving or doing anything that requires concentration or mental alertness.

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Liver

Caution

Daonil Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor, depending on your liver function tests.

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Kidney

Unsafe

Daonil Tablet is unsafe, especially if you have a history of kidney diseases/conditions.

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Children

Unsafe

Daonil Tablet is not recommended for children below the age of 18 years. The safety and effectiveness of Daonil Tablet have not been established in children due to limited evidence. So, only take Daonil Tablet if the doctor has prescribed you.

FAQs

Daonil Tablet is used to treat type-2 diabetes, a chronic or lifelong condition affecting how the body processes glucose.

Daonil Tablet contains Glibenclamide, which increases the amount of insulin released by the pancreas. It stimulates insulin secretion from the pancreas and decreases blood sugar levels. In a nutshell, it prevents blood glucose levels from rising to very high levels, thus keeping your diabetes under control.

Yes, Daonil Tablet can cause constipation. Eat a proper well-balanced diet and drink plenty of fluid to avoid it.

Yes, Daonil Tablet is known to cause an upset stomach if taken empty stomach. So, it should be preferably taken with a meal or just after a meal to avoid an upset stomach.

No, Daonil Tablet is only prescribed for the treatment for the type 2 diabetes along with a healthy diet and lifestyle. It should not be taken for the treatment of type 1 diabetes.

Hypoglycemia refers to low blood sugar levels. The symptoms of hypoglycemia (low blood sugar) include sweating, feeling shaky or anxious, looking pale, feeling hungry, feeling dizzy, and feeling that your heart is pounding (palpitations). Daonil Tablet can cause hypoglycemia. Hypoglycemia can occur if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with Daonil Tablet . People with diabetes are advised to keep a quick sugar source like glucose tablets, honey or fruit juice.

Country of origin

India

Manufacturer/Marketer address

CT Survey No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072.
Other Info - DAO0001

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