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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Last Updated Oct 9, 2024 | 12:36 PM IST
Genticyn 80 mg Injection 2 ml is an antibiotic used in the treatment of bacterial infections of the ear, nose, throat, respiratory tract, gastrointestinal tract, biliary tract, bone and joint, skin and soft tissue. It helps by inhibiting the protein synthesis of the bacterial cell and thereby helps fight infection causing bacteria. This medicine is not effective for treating viral infections.
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Composition

GENTAMICIN-80MG

Manufacturer/Marketer

Abbott India Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Genticyn 80 mg Injection 2 ml

Genticyn 80 mg Injection 2 ml belongs to the class of 'antibiotics', primarily used to treat serious bacterial infections. Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly. 

Genticyn 80 mg Injection 2 ml is composed of Gentamicin, an aminoglycoside antibiotic. It prevents bacteria from synthesising essential proteins required to carry out vital functions. It has broad-spectrum activity against aerobic gram-positive and gram-negative bacteria. 

Genticyn 80 mg Injection 2 ml will be administered by a healthcare professional. Genticyn 80 mg Injection 2 ml may cause a few side effects, although not everybody gets them. Common side effects of Genticyn 80 mg Injection 2 ml include stomach upset, nausea, vomiting, loss of appetite, weight loss, light-headedness, headache, mood changes, joint pain, itching or rash, pain and swelling at the injection site. Most of these side effects do not require medical attention and gradually resolve over time. If these side effects persist longer, please consult your doctor.

Let your doctor know if you have any allergic reactions to medicines, liver/kidney problems, cystic fibrosis (a genetic disorder that affects the digestive and respiratory system), hearing problems, electrolyte imbalance, myasthenia gravis (muscular weakness), or Parkinson's disease before starting Genticyn 80 mg Injection 2 ml. Genticyn 80 mg Injection 2 ml should be used only with a doctor's advice during pregnancy and breastfeeding. Genticyn 80 mg Injection 2 ml may cause light-headedness; in such cases, please do not drive until you are alert. Genticyn 80 mg Injection 2 ml may cause dizziness/vertigo; hence avoid or limit alcohol consumption. 

Uses of Genticyn 80 mg Injection 2 ml

Treatment of Bacterial infections

Medicinal Benefits

Genticyn 80 mg Injection 2 ml is an antibiotic that treats severe/serious bacterial infections. It contains Gentamicin which works by inhibiting bacterial protein synthesis, thus inhibiting bacterial growth. It shows a bacteriostatic effect, which stops bacterial reproduction but doesn't kill them. Genticyn 80 mg Injection 2 ml is useful in treating recurrent infections of kidneys, urinary ducts and bladder, lungs and airways infections during hospitalization, infections of the skin and soft tissues, including burns, and sepsis (blood poisoning by bacteria).

Directions for Use

Genticyn 80 mg Injection 2 ml will be administered by a healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Genticyn 80 mg Injection 2 ml

  • Stomach Upset
  • Nausea
  • Vomiting
  • Loss of appetite 
  • Weight loss
  • Light-headedness
  • Headache
  • Mood changes
  • Joint pain
  • Itching or rash 
  • Pain and swelling at the injection site

Drug Warnings

Brief your medical history to the doctor if you are allergic to any of the components in Genticyn 80 mg Injection 2 ml. Let your doctor know if you have any liver/kidney problems, cystic fibrosis, hearing problems, low blood minerals, myasthenia gravis, or Parkinson's disease. Inform your doctor if you are pregnant or breastfeeding before starting this medicine. Genticyn 80 mg Injection 2 ml may cause dizziness; hence drive or operate machinery only when you are alert. Avoid alcohol consumption to prevent any undesired effects like dizziness while undergoing treatment. 

Drug Interactions

Drug-Drug Interaction: Genticyn 80 mg Injection 2 ml may interact with antibiotics (amikacin, cefixime, clindamycin, polymyxin B, vancomycin), antifungals (amphotericin B), anticancer drugs (cisplatin), water pills (furosemide), immunosuppressants (cyclosporine), nonsteroidal anti-inflammatory drugs (indomethacin, ibuprofen), skeletal muscle relaxants (tubocurarine), myasthenia gravis medicines (neostigmine), and HIV drugs (zalcitabine).

Drug-Food Interaction: Alcohol consumption should be avoided to prevent adverse effects.

Drug-Disease Interaction: Let your doctor know if you have any liver or kidney diseases, cystic fibrosis, hearing problems, low blood minerals, myasthenia gravis, or Parkinson's disease.

Drug-Drug Interactions Checker List

  • AMIKACIN
  • CEFIXIME
  • CLINDAMYCIN
  • POLYMYXIN B
  • VANCOMYCIN
  • AMPHOTERICIN B
  • CISPLATIN
  • FUROSEMIDE
  • CYCLOSPORINE
  • INDOMETHACIN
  • IBUPROFEN
  • TUBOCURARINE
  • NEOSTIGMINE
  • ZALCITABINE

Habit Forming

No

Diet & Lifestyle Advise

  • Wash your hands often to maintain cleanliness.
  • Include whole-grain foods like multigrain bread and brown rice in your diet. 
  • Taking probiotics after an antibiotic treatment reduces the risk of antibiotic-associated diarrhoea. 
  • Try taking yoghurt, cheese, sauerkraut, and kimchi that help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet that is easily digested by your gut bacteria. Fibre foods may also help restore healthy gut bacteria after a course of antibiotics. 
  • Avoid intake of alcoholic beverages as it can make you dehydrated and affect your sleep. 
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep. 

Special Advise

  • Liver and kidney function monitoring (Liver and kidney function tests) are recommended in patients with severe liver and kidney diseases.
  • Clostridium difficile-associated diarrhoea (CDAD) is reported during the usage of antibiotics. Please consult your doctor if you experience prolonged diarrhoea.

Disease/Condition Glossary

Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly. Bacteria occur in three basic shapes: spherical, rod and spiral-shaped. Bacteria may be gram-positive (have a thick cell wall) or gram-negative (do not have a cell wall). Some common symptoms of a bacterial infection include cough, fever, shortness of breath, chills, muscle pain, fatigue, and tiredness. Untreated bacterial infections may lead to serious life-threatening conditions like sepsis.

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Alcohol

Caution

Limit or avoid alcohol intake while being treated with Genticyn 80 mg Injection 2 ml since it may worsen side effects like dizziness.

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Pregnancy

Caution

Genticyn 80 mg Injection 2 ml should be cautiously administered during pregnancy since there are chances of fetal harm. Please consult your doctor before taking Genticyn 80 mg Injection 2 ml if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Genticyn 80 mg Injection 2 ml can be excreted into breast milk in small amounts when used by a nursing mother. Please consult your doctor before taking Genticyn 80 mg Injection 2 ml if you are breastfeeding.

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Driving

Caution

Genticyn 80 mg Injection 2 ml may cause side effects like dizziness or vertigo that could affect your driving ability. Do not drive or operate machinery in such cases. Drive only when you are mentally alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Genticyn 80 mg Injection 2 ml since it may cause abnormal liver function tests.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases or impairment before taking Genticyn 80 mg Injection 2 ml. Dose adjustment may be required.

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Children

Caution

Genticyn 80 mg Injection 2 ml should be used for children only when prescribed by a doctor. The dose may depend on the child's age and body weight.

Country of origin

India

Manufacturer/Marketer address

401, LSC, C-Block, Mohan Place Saraswati Vihar Delhi DL 110034 In
Other Info - GEN0020

Author Details

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FAQs

Genticyn 80 mg Injection 2 ml belongs to the class of 'antibiotics', primarily used to treat serious bacterial infections. Bacterial infection occurs when harmful bacteria grow in the body and causes illness.
Genticyn 80 mg Injection 2 ml is an antibiotic that treats bacterial infections. It works by inhibiting bacterial protein synthesis, which retards bacterial growth.
Genticyn 80 mg Injection 2 ml should be used with proper caution and doctor consultation if you have any allergic reactions to medicines, liver/kidney problems, cystic fibrosis, hearing problems, low blood minerals/electrolyte imbalance, myasthenia gravis (muscular weakness), and Parkinson's disease.
Genticyn 80 mg Injection 2 ml can affect the live vaccines like typhoid vaccine and decrease its effectiveness. Please consult a doctor if you are undergoing any vaccinations.
Genticyn 80 mg Injection 2 ml may cause abnormal liver function tests as one of its side effects. It may increase the levels of liver enzymes and blood bilirubin. Please consult your doctor before starting Genticyn 80 mg Injection 2 ml if you have any history of liver problems.
Diarrhoea can be a side-effect of Genticyn 80 mg Injection 2 ml. Clostridium difficile-associated diarrhoea (CDAD) is also reported during usage of antibiotics like Genticyn 80 mg Injection 2 ml. Therefore, when the patient has diarrhoea, undergoing an examination is advised to rule out the chances of CDAD following Genticyn 80 mg Injection 2 ml therapy.

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