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Prescription drug
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Manufacturer/Marketer

Alkem Laboratories Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-25

for this medicine

About Gemfrac 600 MCG Injection

Gemfrac 600 MCG Injection belongs to the class of medication called 'anabolic (promoting bone formation) agent' indicated for prevention and treatment of osteoporosis in adults and helps to strengthen the bone. This medicine also helps to reduce the risk of spine and hip fractures. Osteoporosis is a medical condition in which bone becomes thin or weak. The chance of developing osteoporosis increases with age, after menopause or by taking corticosteroid medications (such as prednisone) for a long period. If proper treatment is not provided then it can even result in broken bones.

Gemfrac 600 MCG Injection contains Teriparatide a synthetic form of the human parathyroid hormone, which helps to regulate calcium metabolism. Gemfrac 600 MCG Injection works by causing the body to build new bone by increasing bone strength and bone mass density (BMD) (thickness) and reduce the risk of fractures by stimulating bone formation. It also increases the thickness of bone and rebuilds bones which reduces the risk of spine and hip fractures.

Gemfrac 600 MCG Injection will be administered by a healthcare professional; do not self-administer. In some cases, Gemfrac 600 MCG Injection can cause side effects like nausea, vomiting,  joint pain, leg cramps, swelling/redness at the injection site, upset stomach, diarrhea, constipation, runny nose, cough, and throat irritation. Most of these side effects of Gemfrac 600 MCG Injection do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

To treat your condition effectually, continue taking Gemfrac 600 MCG Injection for as long as your doctor has prescribed. Consult your doctor before taking Gemfrac 600 MCG Injection if you are pregnant or breastfeeding; your doctor will prescribe you Gemfrac 600 MCG Injection only if the benefits outweigh the risks. Gemfrac 600 MCG Injection is not recommended for children below 18 years of age.  Tell your doctor that you are taking Gemfrac 600 MCG Injection before you have any lab test as this medicine could interfere with the results. Gemfrac 600 MCG Injection may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up. Inform your doctor about your health condition and medications before taking Gemfrac 600 MCG Injection to rule out any side effects. Gemfrac 600 MCG Injection is a cold chain medicine, and so it has to be stored in the refrigerator between 2-8 degrees Celsius else its efficiency might be lost. Do not store in the freezer or the fridge.

Uses of Gemfrac 600 MCG Injection

Treatment of Osteoporosis, Postmenopausal osteoporosis

Medicinal Benefits

Gemfrac 600 MCG Injection is a synthetic form of a natural human hormone called parathyroid hormone (PTH) that is prescribed to prevent and treat osteoporosis in persons with weak bones. It prevents the loss of bones that happens after menopause and helps to rebuild bones. Gemfrac 600 MCG Injection contains Teriparatide which works by causing the body to build new bone and by increasing bone strength and bone mass density (BMD) (thickness) and reduce the risk of fractures by stimulating bone formation. It also increases the thickness of bone and rebuilds bones which reduces the risk of spine and hip fractures. Gemfrac 600 MCG Injection is also indicated for the treatment of increasing bone mass in people with osteoporosis, glucocorticoid-induced osteoporosis.

Side Effects of Gemfrac 600 MCG Injection

  • Nausea
  • Vomiting
  • Joint pain,
  • Leg cramps
  • Swelling/redness at the injection site
  • Feeling dizzy, tired, or weak
  • Upset stomach
  • Diarrhea 
  • Constipation
  • Runny nose
  • Cough
  • Throat irritation

Directions for Use

Gemfrac 600 MCG Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Gemfrac 600 MCG Injection is not recommended if you have hypercalcemia (high calcium levels) or an overactive parathyroid gland, metastatic calcification (extra deposits of calcium in the body) and malabsorption syndrome (difficulty absorbing nutrition from food), kidney stones, kidney problems (moderate renal impairment), Paget’s disease of bone (abnormal bone changes), history of skeletal malignancies. It is important that your doctor check your progress regularly to make sure that Gemfrac 600 MCG Injection is working properly. Blood and urine tests may be needed to check for unwanted effects. Gemfrac 600 MCG Injection can increase the amount of calcium in your blood or urine. Talk to your doctor before or while using Gemfrac 600 MCG Injection if you have continuing nausea, vomiting, constipation, low energy or muscle weakness. These may be signs there is too much calcium in your blood. Consult your doctor before taking Gemfrac 600 MCG Injection if you are pregnant or breastfeeding; your doctor will prescribe you Gemfrac 600 MCG Injection only if the benefits outweigh the risks. Gemfrac 600 MCG Injection should not be given to children as safety and efficacy have not been established. Do not take Gemfrac 600 MCG Injection for longer durations unless prescribed by your doctor. If your condition does not improve even after taking the Gemfrac 600 MCG Injection full course, please consult your doctor.  Gemfrac 600 MCG Injection may increase the risk of having cancer while taking longer durations. Talk to your doctor if you have concerns about this risk. Avoid consuming alcohol along with Gemfrac 600 MCG Injection as it could lead to increased drowsiness. Inform your doctor about your health condition and medications before taking Gemfrac 600 MCG Injection to rule out any side effects.

Therapeutic Class

BONE ENHANCERS

Drug Interactions

Drug-Drug interaction: Gemfrac 600 MCG Injection may interact with a medicine used to treat heart disease (digoxin, digitalis), medication is used to treat psoriasis (calcitriol topical, calcipotriene topical), water pills (furosemide, hydrochlorothiazide).

Drug-Food interaction: No interaction found.

Drug-Disease interaction: Gemfrac 600 MCG Injection is not allowed to use in some patients dealing with hyperparathyroidism, malignancy (cancer), metabolic bone disorder, orthostatic hypotension (low blood pressure when standing up from sitting or lying down), renal impairment, urolithiasis (stone formation in the bladder or urinary tract).

Drug-Drug Interactions Checker List

  • DIGOXIN
  • DIGITALIS
  • CALCITRIOL
  • CALCIPOTRIENE
  • FUROSEMIDE
  • HYDROCHLOROTHIAZIDE

Diet & Lifestyle Advise

  • A person should consume calcium and vitamin D in their diet as it helps make stronger bones and avoid everyday osteoporosis dangers.
  • A post-menopausal woman should limit salt intake as it can pose a high risk of losing more bone minerals than other women of the same age.
  • Do regular exercise like weight-bearing exercises which are important for maintaining bone health.
  • Calcium is important for making bones strong. Vitamin D is equally important, which helps to ensure the absorption and retention of calcium in bones, so take food high in calcium and vitamins.

Habit Forming

No

What if I have taken an overdose of Gemfrac 600 MCG Injection

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include nausea, vomiting, dizziness, headache, lightheadedness/fainting on standing, constipation, lack of energy, and muscle weakness. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Special Advise

  • Certain diagnostic test like blood test measures the level of calcitonin in your blood and bone density scan is used to check bone mineral density (BMD).
  • Gemfrac 600 MCG Injection should not be prescribed for patients at increased baseline risk of osteosarcoma (bone cancer).
  • Clinical monitoring of urine tests or serum electrolyte concentrations is recommended.
  • Do not take Gemfrac 600 MCG Injection for longer durations unless prescribed by your doctor.

Disease/Condition Glossary

Osteoporosis: It is a medical condition that causes thinning and weakening of the bones. The chance of developing osteoporosis increases with age, after menopause or by taking corticosteroid medications (such as prednisone) for a long period. If proper treatment is not provided then it can even result in broken bones. In starting days, osteoporosis does not show any symptoms.  However, if proper treatment is not provided then it can even lead to broken bones. In Osteoporosis, bones can break at any time even during daily activities like lifting or even from minor activities. Fractures usually occur at the hip, spine or wrist which can even lead to stooped posture (‘dowager’s hump’) and loss of movement.

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Gemfrac 600 MCG Injection. Alcohol intake, along with Gemfrac 600 MCG Injection, may cause increased drowsiness.

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Pregnancy

Caution

It is advised not to take Gemfrac 600 MCG Injection if you are pregnant unless prescribed by the doctor as Gemfrac 600 MCG Injection is a pregnancy category C drug. Your doctor will prescribe Gemfrac 600 MCG Injection only if the benefits outweigh the risks.

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Breast Feeding

Caution

It isn’t known if Gemfrac 600 MCG Injection passes into breast milk. If it does, it may cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your child.

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Driving

Caution

It may cause dizziness, fatigue and blurring of vision; do not drive or operate heavy machinery if you feel drowsy.

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Liver

Caution

Dose adjustment may be needed. Gemfrac 600 MCG Injection should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Tell your doctor if you have kidney disorders as after checking the health condition, a doctor will decide that this medicine is safe to prescribe or not.

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Children

Caution

Gemfrac 600 MCG Injection should not be given to children or adolescents whose age is less than 18 years. Safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - GEM0347

Author Details

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FAQs

Gemfrac 600 MCG Injection is used to treat osteoporosis (weak and brittle bones).
Gemfrac 600 MCG Injection contains Teriparatide is a synthetic form of a natural human hormone called parathyroid hormone (PTH). It works by increasing the number and activity of bone-forming cells (osteoblasts). This strengthens the bones and minimizes the risk of fractures.
Gemfrac 600 MCG Injection can cause kidney stones due to excess calcium deposition when used for a prolonged period. Please consult your doctor before taking Gemfrac 600 MCG Injection as a daily supplement if you have any kidney problems or a history of kidney stones.
Persons whose age is more than 35 years have low estrogen levels, female reaching menopause, too much consumption of alcohol, tobacco, or caffeine, use of glucocorticoid and lack of calcium and vitamin D in the foods are some of the factors that can increase the risk of osteoporosis.
Gemfrac 600 MCG Injection is a part of a complete program that includes modifications in diet, regular exercise, bone mineral density testing and intake of calcium and vitamin supplements. Follow all the guidelines given by the doctor very closely.
Yes, Gemfrac 600 MCG Injection may increase serum calcium, urinary calcium, and serum uric acid. Inform the person doing the tests that you are taking Gemfrac 600 MCG Injection.
You are not recommended to stop taking Gemfrac 600 MCG Injection without consulting your doctor, as stopping early might affect the treatment's effectiveness. Always follow your doctor’s instructions.
Osteoporosis is a condition that causes bones to become thin and weak. The risk of developing it grows with age, after menopause, or from long-term use of corticosteroid medications like prednisone.
Gemfrac 600 MCG Injection is not a steroid, it belongs to a class of medications called anabolic (promoting bone formation) agent.
You are advised to take Gemfrac 600 MCG Injection for as long as prescribed by a doctor to treat your condition effectively. Prolonged or long-term use of Gemfrac 600 MCG Injection increases the risk of cancer. Therefore, follow your doctor’s instructions and do not self-medicate.
Store Gemfrac 600 MCG Injection in a sterile, airtight tamper-proof container at a temperature of 2°C -8°C. Do not freeze.
Gemfrac 600 MCG Injection is not advised to use in some patients dealing with hyperparathyroidism, malignancy (cancer), metabolic bone disorder, or orthostatic hypotension (low blood pressure when standing up from sitting or lying down), renal impairment, urolithiasis (stone formation in the bladder or urinary tract). However, please consult a doctor if you have any concerns.
You are recommended to inform your doctor about any other medications, or supplements, you are using before starting Gemfrac 600 MCG Injection. This ensures potential interactions or side effects are avoided. Always follow your doctor’s guidance when combining treatments.
Gemfrac 600 MCG Injection is not recommended during pregnancy unless advised by a doctor, as there is no sufficient data on its safety for the mother or baby. If pregnancy is detected, consult your doctor immediately to evaluate the risks and discontinue use if necessary.
Gemfrac 600 MCG Injection has side effects such as nausea, joint pain, vomiting, leg cramps, swelling, upset stomach, diarrhoea, constipation, running nose, cough, and throat infection. These are temporary and do not require any medical treatment as they gradually reduce over time. Please, consult a doctor if these side effects persist.
Avoid using Gemfrac 600 MCG Injection if you have conditions like hypercalcemia, kidney stones, or Paget’s disease (abnormal bone growth). Regular blood and urine tests are essential to monitor calcium levels. Avoid use during pregnancy, breastfeeding, or in children unless advised by a physician. Alcohol should be avoided to prevent excessive drowsiness. Always inform your doctor your medical history and medications you are taking.

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Keep Refrigerated. Do not freeze.Prepaid payment required.

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