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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Flupez 25 mg Injection 1 ml is used to treat psychotic disorders like schizophrenia. It contains 'Fluphenazine' that affects the balance of the neurotransmitters in the brain. It helps clear thinking and relieves psychotic symptoms like delusions, hostility, and hallucinations in schizophrenia. Common side effects of Flupez 25 mg Injection 1 ml include lethargy/tiredness, drowsiness, headache, dizziness, blurred vision, nausea, loss of appetite, dry mouth, constipation, stuffy nose, sweating, weight changes, and pain/redness/swelling at the injection site.
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Synonym :

FLUPHENAZINE DECANOATE

Composition :

FLUPHENAZINE-25MG

Manufacturer/Marketer :

Tripada Healthcare Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Flupez 25 mg Injection 1 ml

Flupez 25 mg Injection 1 ml belongs to a group of medicines called 'antipsychotics/neuroleptics,' primarily used to treat psychotic disorders like schizophrenia. Schizophrenia is a mental condition in which the person may feel, hear or see things that are not there (hallucinations), believe things that are not true, and feel unusually suspicious or confused. 

Flupez 25 mg Injection 1 ml contains 'Fluphenazine' that belongs to the class of phenothiazines. It works by affecting the balance of the neurotransmitters in the brain. Thereby, Flupez 25 mg Injection 1 ml decreases psychotic symptoms like hallucinations, delusions, and hostility (unfriendly or opposed behaviour) associated with schizophrenia. Flupez 25 mg Injection 1 ml is intended for use in the management of patients requiring prolonged parenteral antipsychotic therapy.

Your doctor will decide the dose and duration based on your medical condition and response to treatment. Common side effects of Flupez 25 mg Injection 1 ml include lethargy/tiredness, drowsiness, headache, dizziness, blurred vision, nausea, loss of appetite, dry mouth, constipation, stuffy nose, sweating, weight changes, and pain/redness/swelling at the injection site. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Flupez 25 mg Injection 1 ml is not recommended for treatment in patients with dementia-related psychosis. Inform your doctor before starting Flupez 25 mg Injection 1 ml if you have a history of liver/kidney/heart diseases, breathing problems, blood cell disorder, Parkinson's disease, glaucoma, breast cancer, depression, or fits. If you are pregnant, planning to conceive, or a breastfeeding mother, inform your doctor before starting Flupez 25 mg Injection 1 ml. Avoid consuming alcohol while being treated with Flupez 25 mg Injection 1 ml as it can make you dizzy or drowsy. Do not drive or operate machinery since it can make you sleepy and interfere with your driving ability. Flupez 25 mg Injection 1 ml is not approved for children younger than 12 years of age.

Uses of Flupez 25 mg Injection 1 ml

Treatment of Schizophrenia

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Flupez 25 mg Injection 1 ml is used to treat schizophrenia and associated psychotic symptoms. It contains 'Fluphenazine' that affects the balance of the neurotransmitters in the brain. It helps clear thinking and relieves psychotic symptoms like delusions, hostility, and hallucinations in schizophrenia.

How Flupez 25 mg Injection 1 ml Works

Flupez 25 mg Injection 1 ml contains 'Fluphenazine' that belongs to the class of phenothiazines. It works by affecting the balance of the neurotransmitters in the brain. Thereby, Flupez 25 mg Injection 1 ml decreases psychotic symptoms like hallucinations, delusions, and hostility (unfriendly or opposed behaviour) associated with schizophrenia. Flupez 25 mg Injection 1 ml is intended for use in the management of patients requiring prolonged parenteral antipsychotic therapy.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Flupez 25 mg Injection 1 ml

  • Lethargy/tiredness
  • Drowsiness
  • Headache
  • Dizziness
  • Blurred vision
  • Nausea
  • Loss of appetite
  • Dry mouth
  • Constipation
  • Stuffy nose
  • Sweating
  • Weight changes
  • Pain/swelling/redness at the injection site

What if I have taken an overdose of Flupez 25 mg Injection 1 ml

As Flupez 25 mg Injection 1 ml is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Flupez 25 mg Injection 1 ml is not recommended for treatment in patients with dementia-related psychosis. Before using Flupez 25 mg Injection 1 ml, let your doctor know if you have a medical history of liver or kidney diseases, heart problems, breathing problems (asthma), pheochromocytoma, fits, glaucoma, blood problems (leukopenia, thrombocytopenia), Parkinson's disease, low blood calcium levels, enlarged prostate, depression, or breast cancer. Please consult your doctor if you are pregnant, planning to conceive or a breastfeeding mother before starting Flupez 25 mg Injection 1 ml. Avoid consuming alcohol during the treatment, as it might lead to increased dizziness and drowsiness. Avoid driving or operating machinery, as this medicine may decrease your mental alertness, making you feel dizzy or drowsy. Flupez 25 mg Injection 1 ml is not recommended for children below 12 years of age as safety and effectiveness have not been established.

Drug-Drug Interactions

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FluphenazineHaloperidol
Critical
FluphenazineZiprasidone
Critical

Drug-Drug Interactions

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FluphenazineHaloperidol
Critical
How does the drug interact with Flupez 25 mg Injection 1 ml:
Coadministration of Flupez 25 mg Injection 1 ml and Haloperidol can increase the risk of developing irregular heart rhythms.

How to manage the interaction:
Taking Flupez 25 mg Injection 1 ml and Haloperidol together is generally avoided as it can lead to an interaction, but it can be taken when a doctor advises. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
FluphenazineZiprasidone
Critical
How does the drug interact with Flupez 25 mg Injection 1 ml:
Taking ziprasidone with Flupez 25 mg Injection 1 ml can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Flupez 25 mg Injection 1 ml is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
FluphenazineEscitalopram
Severe
How does the drug interact with Flupez 25 mg Injection 1 ml:
Combining Flupez 25 mg Injection 1 ml with Escitalopram can increase the risk of adverse effects.

How to manage the interaction:
Taking Escitalopram with Flupez 25 mg Injection 1 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - dizziness, feeling lightheaded or faint, heart palpitations, irregular heart rhythm, difficulty breathing, a heart condition, or severe and prolonged diarrhea or vomiting, contact your doctor right away. Do not stop using any medications without talking to your doctor.
FluphenazineMethimazole
Severe
How does the drug interact with Flupez 25 mg Injection 1 ml:
Co-administration of Flupez 25 mg Injection 1 ml and Methimazole together can cause the risk of neutropenia leading to serious infections.

How to manage the interaction:
Although there is a possible interaction between Methimazole and Flupez 25 mg Injection 1 ml, you can take these medicines together if prescribed by a doctor. If you notice any of these signs - fever, chills, body aches, sore throat, coughing, breathing difficulties, mouth ulcers, or flu-like symptoms - contact a doctor right away. Do not stop using any medications without talking to a doctor.
FluphenazineGatifloxacin
Severe
How does the drug interact with Flupez 25 mg Injection 1 ml:
Taking Gatifloxacin and Flupez 25 mg Injection 1 ml can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Gatifloxacin and Flupez 25 mg Injection 1 ml together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FluphenazineAmisulpride
Severe
How does the drug interact with Flupez 25 mg Injection 1 ml:
Taking amisulpride with Flupez 25 mg Injection 1 ml increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking amisulpride along with Flupez 25 mg Injection 1 ml can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
FluphenazineMorphine
Severe
How does the drug interact with Flupez 25 mg Injection 1 ml:
Taking Morphine with Flupez 25 mg Injection 1 ml may increase the risk of central nervous system depression, which can lead to breathing difficulty and unconsciousness.

How to manage the interaction:
Coadministration of Morphine and Flupez 25 mg Injection 1 ml together can cause an interaction, it can be taken if a doctor has suggested it. However, if you notice any symptoms like dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FluphenazinePentazocine
Severe
How does the drug interact with Flupez 25 mg Injection 1 ml:
Taking Flupez 25 mg Injection 1 ml with Pentazocine can increase the risk of serious side effects.

How to manage the interaction:
Although there is a possible interaction between Pentazocine and Flupez 25 mg Injection 1 ml, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment. Do not discontinue any medications without consulting your doctor.
FluphenazineCeritinib
Severe
How does the drug interact with Flupez 25 mg Injection 1 ml:
Taking Ceritinib together with Flupez 25 mg Injection 1 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Ceritinib and Flupez 25 mg Injection 1 ml, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.
FluphenazineDisopyramide
Severe
How does the drug interact with Flupez 25 mg Injection 1 ml:
The combined use of Flupez 25 mg Injection 1 ml and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Flupez 25 mg Injection 1 ml and Disopyramide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain proper weight by following a healthy diet.
  • Exercise regularly as it helps in less cognitive decline and brain volume loss.
  • Avoid smoking and alcohol consumption.
  • Try to avoid stress by practising meditation or yoga.
  • Include fruits and vegetables in your diet as they contain antioxidants.
  • Eat nutritious food as it helps in cognitive stimulation.
  • Limit foods with high cholesterol and saturated fats.
  • Cut down on sugar, salt and processed foods.
  • Drink plenty of water.
  • Follow a regular sleep pattern.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

Flupez 25 mg Injection 1 ml Substitute

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Alcohol

Unsafe

It is advised to avoid alcohol consumption while using Flupez 25 mg Injection 1 ml. Alcohol intake while being treated with Flupez 25 mg Injection 1 ml, may cause increased dizziness and drowsiness. Please consult your doctor for more information.

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Pregnancy

Caution

Using antipsychotic drugs during the third trimester of pregnancy may cause muscle problems in newborn babies. Please consult your doctor before using Flupez 25 mg Injection 1 ml if you are pregnant or planning to conceive. Your doctor will weigh the potential risks and benefits before prescribing Flupez 25 mg Injection 1 ml.

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Breast Feeding

Caution

It is not known if Flupez 25 mg Injection 1 ml is excreted into the breast milk. Please consult your doctor before using Flupez 25 mg Injection 1 ml if you are a breastfeeding mother.

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Driving

Unsafe

Flupez 25 mg Injection 1 ml may make you feel dizzy or drowsy. Do not drive if you are not mentally alert or experience any symptoms that affect your ability to drive or operate machinery.

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Liver

Caution

If you have a history of liver disease, inform your doctor before receiving Flupez 25 mg Injection 1 ml. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a history of kidney disease, inform your doctor before receiving Flupez 25 mg Injection 1 ml. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Flupez 25 mg Injection 1 ml is not recommended for children younger than 12 years of age.

FAQs

Flupez 25 mg Injection 1 ml is used to treat Schizophrenia.
Flupez 25 mg Injection 1 ml contains Fluphenazine, an antipsychotic medication that affects the balance of neurotransmitters in the brain, thus improving mood, behaviour, and thoughts in schizophrenia.
Before using Flupez 25 mg Injection 1 ml, let your doctor know if you have a medical history of liver or kidney diseases, heart problems (history of stroke), breathing problems (asthma, emphysema), pheochromocytoma (adrenal gland tumour), Parkinson's disease, fits, low white blood cells, glaucoma, blood problems (leukopenia, thrombocytopenia), low blood calcium levels, enlarged prostate, breast cancer, and Reye's syndrome (a rare, but serious condition that causes swelling in the brain and liver damage). Please let your doctor know if you have any other medical problems before starting Flupez 25 mg Injection 1 ml.
Flupez 25 mg Injection 1 ml is not recommended for older dementia patients since it can lead to serious side effects like heart failure, fast/irregular heartbeat, and pneumonia. However, please discuss with the doctor possibly safer treatments for dementia-related behaviour problems.
Flupez 25 mg Injection 1 ml may cause dizziness. It is advised to avoid getting up too fast from a sitting or lying position that can make you feel dizzy.
Dry mouth could be a side-effect of Flupez 25 mg Injection 1 ml. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and prevent drying of the mouth.

Country of origin

India

Manufacturer/Marketer address

3 Yogi Complex, Nr Doordarshan, Kendra, Thaltej, Ahmedabad, India 380054.
Other Info - FLU0947

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