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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Firstdep-40 Capsule is used to treat a major depressive disorder, obsessive-compulsive disorder (OCD), bulimia nervosa (eating disorder), and panic disorder. It contains Fluoxetine, which increases serotonin concentrations and helps in regulating mood and treats depression. In some cases, you may experience common side effects such as insomnia (difficulty sleeping), headache, diarrhoea, nausea, fatigue, dry mouth, loss of appetite, and indigestion. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

FLUOXETINE-40MG

Manufacturer/Marketer :

Myk Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Firstdep-40 Capsule

Firstdep-40 Capsule belongs to a group of medicines called antidepressants used to treat a major depressive disorder, obsessive-compulsive disorder (OCD), bulimia nervosa (eating disorder), and panic disorder. Depression is a mood disorder characterised by the feeling of sadness, unhappiness, anger, hopelessness or loss that interferes with a person’s daily activities.
 
Firstdep-40 Capsule contains ‘Fluoxetine’ which is a selective serotonin reuptake inhibitor. It works by inhibiting the reuptake of serotonin by nerves, a mood-enhancing chemical messenger in the brain which communicates between brain cells. This helps in an increase in serotonin concentrations in the nerve synapse, thereby helps in regulating mood and treats depression.
 
Take Firstdep-40 Capsule as prescribed. You are advised to take Firstdep-40 Capsule for as long as your doctor has prescribed it for you depending on your medical condition and response to the treatment. In some cases, you may experience certain common side-effects such as insomnia (difficulty sleeping), headache, diarrhoea, nausea, fatigue, dry mouth, loss of appetite, and indigestion. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Please do not stop taking Firstdep-40 Capsule on your own as it could lead to withdrawal symptoms. Do not take Firstdep-40 Capsule if you are pregnant or breastfeeding unless prescribed. Do not drive or operate machinery as Firstdep-40 Capsule may cause dizziness and might impair your reactions. Firstdep-40 Capsule should not be given to children below 8years as the safety and effectiveness have not been established. Avoid consuming alcohol along with Firstdep-40 Capsule as it could lead to increased dizziness.  Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Firstdep-40 Capsule

Treatment of Depression, Obsessive-Compulsive Disorder (OCD), Bulimia nervosa (eating disorder).

Directions for Use

Take Firstdep-40 Capsule with or without food. Your doctor will decide for how long you need to take Firstdep-40 Capsule based on your medical condition and response to treatment. Take Firstdep-40 Capsule exactly as prescribed by the doctor. Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew, or crush the tablet/capsule.Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack; shake the pack well before each use.

Medicinal Benefits

Firstdep-40 Capsule belongs to a group of antidepressant medicines called selective serotonin reuptake inhibitors. Firstdep-40 Capsule is used to treat major depressive disorder, obsessive-compulsive disorder (OCD), bulimia nervosa (eating disorder), and panic disorder with or without agoraphobia. Firstdep-40 Capsule works by inhibiting the reuptake of serotonin by nerves, a mood-enhancing chemical messenger in the brain which communicates between brain cells. This helps in an increase in serotonin concentrations in the nerve synapse, thereby helps in regulating mood and treats depression. Firstdep-40 Capsule may also be used to treat premenstrual dysphoric disorder (a severe form of premenstrual syndrome). Firstdep-40 Capsule has fewer unwanted effects than other antidepressant drugs. Firstdep-40 Capsule is used in combination with other drugs to treat bipolar disorder and treatment-resistant depression.

How Firstdep-40 Capsule Works

Firstdep-40 Capsule contains ‘Fluoxetine’ which is a selective serotonin reuptake inhibitor. It works by inhibiting the reuptake of serotonin by nerves, a mood-enhancing chemical messenger in the brain which communicates between brain cells. This helps in an increase in serotonin concentrations in the nerve synapse, thereby helps in regulating mood and treats depression.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Firstdep-40 Capsule

  • Insomnia (difficulty sleeping)
  • Headache
  • Diarrhoea
  • Nausea
  • Fatigue
  • Dry mouth
  • Loss of appetite
  • Indigestion

What if I have taken an overdose of Firstdep-40 Capsule

Do not take more than the prescribed dose of Firstdep-40 Capsule as it may cause overdose. The symptoms of overdose include drowsiness, tremor, fast heart rate, vomiting and nausea. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Firstdep-40 Capsule if you are allergic to any of its contents; if you are taking monoamine oxidase inhibitors (MOA) or have taken them in the last 14days, or if you are taking metoprolol (used to treat high blood pressure). Do not take Firstdep-40 Capsule along with opioid antagonists such as buprenorphine and naloxone as it might lead to a serious condition called serotonin syndrome. Consult your doctor immediately if you have suicidal thoughts such as killing or harming yourself. Inform your doctor if you have/had epilepsy, mania, glaucoma, diabetes, bleeding disorders, or hyponatremia (low sodium levels).  Do not take Firstdep-40 Capsule if you are pregnant or breastfeeding unless prescribed. Do not drive or operate machinery as Firstdep-40 Capsule may cause dizziness and might impair your reactions. Firstdep-40 Capsule should not be given to children below 8years as the safety and effectiveness have not been established. Avoid consuming alcohol along with Firstdep-40 Capsule as it could lead to increased dizziness. 

Drug-Drug Interactions

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FluoxetineDihydroergotamine
Severe
FluoxetineTrazodone
Severe

Drug-Drug Interactions

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FluoxetineDihydroergotamine
Severe
How does the drug interact with Firstdep-40 Capsule 10's:
Co-administration of Dihydroergotamine with Firstdep-40 Capsule 10's can result in effects and also Serotonin syndrome (a condition wherein serotonin levels are increased in the body).

How to manage the interaction:
Although taking Firstdep-40 Capsule 10's and Dihydroergotamine together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs - like confusion, shaking, or stomach discomfort - it's a good idea to reach out to a doctor right away. Do not discontinue any medications without consulting a doctor.
FluoxetineTrazodone
Severe
How does the drug interact with Firstdep-40 Capsule 10's:
Taking Trazodone with Firstdep-40 Capsule 10's can increase the risk of serotonin syndrome (a condition in which serotonin increase in your body).

How to manage the interaction:
Co-administration of Trazodone with Firstdep-40 Capsule 10's can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience confusion, seizure(fits), extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm, tremor (shaking of hands & legs), incoordination, stomach pain, nausea, vomiting, and diarrhea contact a doctor right away. Do not discontinue any medications without consulting a doctor.
FluoxetineRasagiline
Severe
How does the drug interact with Firstdep-40 Capsule 10's:
Taking rasagiline with Firstdep-40 Capsule 10's can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a possible interaction, Firstdep-40 Capsule 10's can be taken with rasagiline if prescribed by the doctor. Consult the doctor if you experience symptoms of serotonin syndrome such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
FluoxetineLinezolid
Severe
How does the drug interact with Firstdep-40 Capsule 10's:
Co-administration of Linezolid with Firstdep-40 Capsule 10's can result in effects and also Serotonin syndrome (a condition wherein serotonin levels are increased in the body).

How to manage the interaction:
Co-administration of linezolid along with Firstdep-40 Capsule 10's can possibly lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
FluoxetineRizatriptan
Severe
How does the drug interact with Firstdep-40 Capsule 10's:
Taking Firstdep-40 Capsule 10's with rizatriptan may increase the risk of a serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a possible interaction between Firstdep-40 Capsule 10's and Rizatriptan, it can be taken if your doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking of hands and legs, incoordination, stomach cramps, nausea, vomiting, and loose stools, contact a doctor. Do not discontinue any medications without consulting a doctor.
FluoxetineDofetilide
Severe
How does the drug interact with Firstdep-40 Capsule 10's:
Combining Firstdep-40 Capsule 10's with Dofetilide can increase the risk of QTc prolongation.

How to manage the interaction:
Taking Firstdep-40 Capsule 10's with Dofetilide together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, it's important to contact your doctor right away: an irregular heart rhythm, a heart condition, congenital long qt syndrome, conduction abnormalities, severe or prolonged diarrhea, vomiting, complications, sudden dizziness, lightheadedness, fainting, shortness of breath, or palpitations. Do not stop using any medications without talking to a doctor.
FluoxetineAtomoxetine
Severe
How does the drug interact with Firstdep-40 Capsule 10's:
Taking Firstdep-40 Capsule 10's may significantly increase the blood levels of atomoxetine. This might increase the side effects.

How to manage the interaction:
Although there is a possible interaction, Firstdep-40 Capsule 10's can be taken with atomoxetine if prescribed by the doctor. Consult the doctor if you experience side effects such as dizziness, dry mouth, loss of appetite, sleep disturbances, and heart palpitations. Do not discontinue any medications without a doctor's advice.
FluoxetineCyclobenzaprine
Severe
How does the drug interact with Firstdep-40 Capsule 10's:
Co-administration of Cyclobenzaprine with Firstdep-40 Capsule 10's might raise serotonin hormone levels which can increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction, Firstdep-40 Capsule 10's can be taken with cyclobenzaprine if prescribed by the doctor. However, if you experience fever, palpitations, excessive sweating, shivering, muscle spasm, or vomiting, contact a doctor immediately. Do not discontinue the medications without consulting a doctor.
FluoxetineAlmotriptan
Severe
How does the drug interact with Firstdep-40 Capsule 10's:
Taking Firstdep-40 Capsule 10's with almotriptan may increase the risk of a serotonin levels in the body.

How to manage the interaction:
Although there is a possible interaction, Firstdep-40 Capsule 10's can be taken with almotriptan if prescribed by the doctor. Consult the doctor if you experience symptoms of serotonin syndrome such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue the medications without consulting a doctor.
FluoxetineVenlafaxine
Severe
How does the drug interact with Firstdep-40 Capsule 10's:
Taking Firstdep-40 Capsule 10's with venlafaxine can cause serotonin syndrome. Serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Although there is a possible interaction, Firstdep-40 Capsule 10's can be taken with venlafaxine if prescribed by the doctor. Consult the doctor if you experience symptoms of serotonin syndrome such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly helps in improving overall health and boosts self-esteem.

  • Regularly attend therapy sessions.

  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.

  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.

  • Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.

  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in the proper maintenance of neurotransmitters. 

  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.

  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosts self-esteem, and provides restful sleep.

  • Avoid smoking and alcohol consumption.

  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

PSYCHOTHERAPEUTICS

Firstdep-40 Capsule Substitute

Substitutes safety advice
  • Flunil Capsule 10's

    6.53per tablet
  • Floatin-40 Tablet 10's

    6.16per tablet
  • Cyclotin-40 Tablet 15's

    by AYUR

    5.58per tablet
  • Floxin 40 Tablet 10's

    6.66per tablet
  • Flutop-40 Tablet 10's

    5.46per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Firstdep-40 Capsule as it may cause increased dizziness.

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Pregnancy

Caution

Firstdep-40 Capsule belongs to pregnancy category C. Please consult your doctor before taking Firstdep-40 Capsule if you are pregnant, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Firstdep-40 Capsule may pass into breastmilk. Consult your doctor before taking Firstdep-40 Capsule ; your doctor will decide whether Firstdep-40 Capsule can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Firstdep-40 Capsule may cause dizziness and might impair your reactions. Do not drive or operate machinery if you experience these symptoms.

bannner image

Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Firstdep-40 Capsule should not be given to children below 8years as the safety and effectiveness have not been established.

FAQs

Firstdep-40 Capsule is used to treat Depression, Obsessive-Compulsive Disorder (OCD), and Bulimia nervosa (eating disorder).
Firstdep-40 Capsule works by inhibiting the reuptake of serotonin by nerves, a mood-enhancing chemical messenger in the brain which communicates between brain cells. This helps in an increase in serotonin concentrations in the nerve synapse, thereby helps in regulating mood and treats depression.
Do not discontinue Firstdep-40 Capsule without consulting your doctor as it could lead to withdrawal effects. To treat your condition effectually continue taking Firstdep-40 Capsule for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Firstdep-40 Capsule ; the doctor may reduce the dose gradually.
Firstdep-40 Capsule may cause decreased sex-drive, problems with erection and orgasm. Consult your doctor if you have any concerns regarding this.
Dry mouth could be a side-effect of Firstdep-40 Capsule . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.
Please consult your doctor before taking Firstdep-40 Capsule if you have glaucoma as it might cause increased pressure in the eye.
Consult tour doctor before taking Firstdep-40 Capsule if you are diabetic as it might fluctuate blood glucose levels. Regular monitoring of blood sugar levels is advised if you are taking Firstdep-40 Capsule . Talk to your doctor if you experience fluctuations in blood sugar levels.
Firstdep-40 Capsule might increase the risk of bone fractures. Talk to your doctor before taking Firstdep-40 Capsule if you have osteoporosis. Consult your doctor if you experience bone pain.
Firstdep-40 Capsule may cause weight loss due to loss of appetite. Eat a healthy diet and exercise regularly to maintain a healthy weight. Please consult your doctor if you experience fluctuations in weight while taking Firstdep-40 Capsule .

Country of origin

India

Manufacturer/Marketer address

100 Southview Cres Suite 1708 Winnipeg, Mb, R3Y 0W1 Canada.
Other Info - FIR0090

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