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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Flutop-40 Tablet is used to treat a major depressive disorder, obsessive-compulsive disorder (OCD), bulimia nervosa (eating disorder), and panic disorder. It contains Fluoxetine, which helps in regulating mood and treating depression. In some cases, you may experience side effects such as insomnia (difficulty sleeping), headache, diarrhoea, nausea, fatigue, dry mouth, loss of appetite, and indigestion. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

FLUOXETINE-40MG

Manufacturer/Marketer :

Crescent Therapeutics Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Flutop-40 Tablet

Flutop-40 Tablet belongs to a group of medicines called antidepressants used to treat major depressive disorder, obsessive-compulsive disorder (OCD), bulimia nervosa (eating disorder), and panic disorder.

Flutop-40 Tablet contains Fluoxetine, which works by increasing serotonin concentrations in the nerve synapse, thereby regulating mood and treating depression.

In some cases, you may experience side effects, such as difficulty sleeping, headache, diarrhoea, nausea, fatigue, dry mouth, loss of appetite, and indigestion. Talk to your doctor if you experience these side effects persistently.

Please do not stop taking Flutop-40 Tablet on your own, as it could lead to withdrawal symptoms. Consult your doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and any medications you are taking to rule out any potential side effects.

Uses of Flutop-40 Tablet

Flutop-40 Tablet is used in the treatment of mental health disorders. The detailed uses of Flutop-40 Tablet are as follows:

  • Treats major depressive disorder: Flutop-40 Tablet helps improve mood, sleep, appetite, and energy levels by balancing neurotransmitters in the brain.
  • Manages obsessive-compulsive disorder (OCD): Flutop-40 Tablet reduces unwanted thoughts and repetitive behaviours that interfere with daily life.
  • Controls bulimia nervosa: Flutop-40 Tablet helps reduce binge-eating and purging behaviours in patients with this eating disorder.
  • Alleviates panic disorder: Flutop-40 Tablet is effective in reducing the frequency and severity of panic attacks.

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Directions for Use

  • Flutop-40 Tablet can be taken with or without food, or as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Flutop-40 Tablet as a whole with a glass of water.
  • Do not chew, crush or break it.

Medicinal Benefits

  • Flutop-40 Tablet belongs to the class of selective serotonin reuptake inhibitors (SSRIs), used to treat depression.
  • It helps in the treatment of major depressive disorder by improving mood and emotional balance.
  • It is used to manage obsessive-compulsive disorder (OCD) by reducing unwanted, repetitive thoughts and compulsive behaviours.
  • Flutop-40 Tablet is also effective in treating bulimia nervosa, an eating disorder characterised by binge eating and purging.
  • It helps control panic disorder, with or without agoraphobia (fear of open or crowded places).
  • Flutop-40 Tablet works by increasing the serotonin levels in the brain, a mood-regulating chemical messenger, thereby improving mood, sleep, and emotional stability.

How Flutop-40 Tablet Works

Flutop-40 Tablet contains Fluoxetine, which is a selective serotonin reuptake inhibitor. It works by inhibiting the reuptake of serotonin by nerves, a mood-enhancing chemical messenger in the brain which communicates between brain cells. This helps increase serotonin concentrations in the nerve synapse, thereby regulating mood and treating depression.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Flutop-40 Tablet

Do not take more than the prescribed dose of Flutop-40 Tablet as it may cause an overdose. The symptoms of overdose include drowsiness, tremor, fast heart rate, vomiting and nausea. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Flutop-40 Tablet if you are allergic to any of its contents; if you are taking monoamine oxidase inhibitors (MAOIs) or have taken them in the last 14 days, or if you are taking metoprolol (used to treat high blood pressure).
  • Avoid taking Flutop-40 Tablet along with opioid antagonists such as buprenorphine and naloxone, as it might lead to a serious condition called serotonin syndrome.
  • Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself.
  • Inform your doctor if you have/had epilepsy, mania, glaucoma, diabetes, bleeding disorders, or hyponatremia (low sodium levels).
  • Consult your doctor if you are pregnant or breastfeeding.
  • Do not drive or operate machinery as Flutop-40 Tablet may cause dizziness and might impair your reactions.
  • Flutop-40 Tablet should not be given to children below 8 years, as the safety and effectiveness have not been established.
  • Avoid consuming alcohol along with Flutop-40 Tablet as it could lead to increased dizziness.
  • Let your doctor know if you are taking any other medicines, including supplements and herbal products.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Flutop-40 Tablet:
Co-administration of Flutop-40 Tablet with mifepristone can increase the risk of irregular heart rhythm. Prolonged treatment with Mifepristone may result in low potassium levels.

How to manage the interaction:
Taking Flutop-40 Tablet with mifepristone together is avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, rapid heartbeat, weakness, tiredness, drowsiness, confusion, painful muscle cramping, nausea, vomiting, constipation, abdominal cramping, chest pain, and/or swelling in the legs or feet, get medical attention. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Flutop-40 Tablet:
Taking Flutop-40 Tablet with citalopram may increase the risk of a rare but serious condition called the serotonin syndrome. Combining these medications can increase the risk of an irregular heart rhythm that may be serious

How to manage the interaction:
Although there is a possible interaction, Flutop-40 Tablet can be taken with citalopram if prescribed by the doctor. Consult the doctor if you experience sudden lightheadedness, dizziness, shortness of breath, fainting, or heart palpitations during treatment with these medications. Let the doctor know if you notice symptoms of serotonin syndrome such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea.
How does the drug interact with Flutop-40 Tablet:
Taking Flutop-40 Tablet with Cisapride may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, Flutop-40 Tablet can be taken with Cisapride if prescribed by the doctor. Consult the doctor if you experience sudden lightheadedness, dizziness, shortness of breath, fainting, or heart palpitations during treatment with these medications. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Flutop-40 Tablet:
Taking Flutop-40 Tablet with disopyramide may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, Flutop-40 Tablet can be taken with disopyramide if prescribed by the doctor. Consult the doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with these medications.
How does the drug interact with Flutop-40 Tablet:
Co-administration of Lithium with Flutop-40 Tablet can result in effects and also Serotonin syndrome (a condition wherein serotonin levels are increased in the body).

How to manage the interaction:
Although there is a interaction between Flutop-40 Tablet and Lithium, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Flutop-40 Tablet:
Taking Flutop-40 Tablet with venlafaxine can cause serotonin syndrome. Serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Although there is a possible interaction, Flutop-40 Tablet can be taken with venlafaxine if prescribed by the doctor. Consult the doctor if you experience symptoms of serotonin syndrome such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue the medications without consulting a doctor.
FluoxetinePhenelzine
Severe
How does the drug interact with Flutop-40 Tablet:
Taking Flutop-40 Tablet with phenelzine may increase the risk of a serotonin levels in the body.

How to manage the interaction:
Although there is a possible interaction, Flutop-40 Tablet can be taken with phenelzine if prescribed by the doctor. Consult the doctor if you experience symptoms of serotonin syndrome such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhoea. Treatment with Flutop-40 Tablet should be started 14 days after stopping phenelzine.
How does the drug interact with Flutop-40 Tablet:
Taking Flutop-40 Tablet with tramadol may increase the risk of a serotonin syndrome. It may also increase the risk of seizures not related to the serotonin syndrome.

How to manage the interaction:
Although there is a possible interaction, Flutop-40 Tablet can be taken with tramadol if prescribed by the doctor. Consult the doctor if you experience symptoms of serotonin syndrome such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Flutop-40 Tablet:
Taking Flutop-40 Tablet with desvenlafaxine might raise serotonin hormone levels in the body and may affect the brain or nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Although there is a possible interaction, Flutop-40 Tablet can be taken with desvenlafaxine if prescribed by the doctor. Consult the doctor if you experience symptoms of serotonin syndrome such as confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Flutop-40 Tablet:
Taking Flutop-40 Tablet with almotriptan may increase the risk of a serotonin levels in the body.

How to manage the interaction:
Although there is a possible interaction, Flutop-40 Tablet can be taken with almotriptan if prescribed by the doctor. Consult the doctor if you experience symptoms of serotonin syndrome such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintaining a healthy diet and exercising regularly helps improve overall health and boosts self-esteem.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga. This helps alleviate stress and promote relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.
  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in the proper maintenance of neurotransmitters. 
  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.
  • Exercising helps in the production of the body’s natural antidepressants. It also helps relieve stress, improve mood, boost self-esteem, and promote restful sleep.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

PSYCHOTHERAPEUTICS

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Flutop-40 Tablet as it may cause increased dizziness.

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Pregnancy

Caution

Flutop-40 Tablet belongs to pregnancy category C. Please consult your doctor before taking Flutop-40 Tablet if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Flutop-40 Tablet may pass into breastmilk. Consult your doctor before taking Flutop-40 Tablet ; your doctor will decide whether breastfeeding mothers can take Flutop-40 Tablet or not.

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Driving

Unsafe

Flutop-40 Tablet may cause dizziness and might impair your reactions. Do not drive or operate machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Flutop-40 Tablet should not be given to children below 8 years as the safety and effectiveness have not been established.

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Heart

Consult your doctor

Please inform your doctor if you have any pre-existing heart problems

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Geriatrics

Safe if prescribed

Flutop-40 Tablet can be safely given in elderly patients if recommended by the physician.

FAQs

Flutop-40 Tablet is used to treat Depression, Obsessive-Compulsive Disorder (OCD), and Bulimia Nervosa (an eating disorder).

Flutop-40 Tablet works by inhibiting the reuptake of serotonin by nerves, a mood-enhancing chemical messenger in the brain which communicates between brain cells. This helps increase serotonin concentrations in the nerve synapse, thereby regulating mood and treating depression.

Do not discontinue Flutop-40 Tablet without consulting your doctor, as it could lead to withdrawal effects. To treat your condition effectually, continue taking Flutop-40 Tablet for as long as prescribed. Do not hesitate to consult your doctor if you experience any difficulties while taking Flutop-40 Tablet ; the doctor may be able to adjust the dose gradually.

Flutop-40 Tablet may cause decreased sex-drive, problems with erection and orgasm. Consult your doctor if you have any concerns regarding this.

Dry mouth may be a side effect of Flutop-40 Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum or candy may help stimulate saliva and thereby prevent mouth dryness.

Country of origin

INDIA

Manufacturer/Marketer address

SCO-58, 59, Sector-17D Chandigarh-160017
Other Info - FLU0034

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