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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Etoplast 100 mg Injection 5 ml is used to treat various cancer conditions, including testicular tumours or cancer of the testicles and lung cancer (small cell lung cancer; SCLC). It contains Etoposide, a podophyllotoxin derivative. It works by inhibiting an enzyme responsible for cancer cell proliferation and induces cell death (apoptosis). As a result, the growth and spread of cancer cells are stopped or slowed down.
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Composition :

ETOPOSIDE-100MG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Etoplast 100 mg Injection 5 ml

Etoplast 100 mg Injection 5 ml belongs to a class of chemotherapy drugs used to treat various cancer conditions, including testicular tumours or cancer of the testicles, lung cancer (small cell lung cancer; SCLC). Besides this, it can also be used in treating Monoblastic leukaemia (AML M5) and acute myelomonoblastic leukaemia (AML M4). Cancer is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues.

Etoplast 100 mg Injection 5 ml contains Etoposide, which is a podophyllotoxin derivative. It works by inhibiting an enzyme responsible for cancer cell proliferation and induces cell death (apoptosis). As a result, the growth and spread of cancer cells are stopped or slowed down.

Etoplast 100 mg Injection 5 ml will be administered by a qualified healthcare professional. Sometimes, Etoplast 100 mg Injection 5 ml may use certain side effects such as myelosuppression (bone marrow activity is decreased), leucopenia (reduction in the number of white cells in the blood), thrombocytopenia (deficiency of platelets), anaemia (deficiency of red cells), anorexia (lack or loss of appetite for food), fatigue (extreme tiredness), drowsiness, nausea, vomiting, alopecia, liver and kidney functional impairment, leukaemia, hypotension, haemorrhage, abdominal pain, diarrhoea, stomatitis (inflammation of the mucous membrane), hepatic dysfunction and increased bilirubin levels etc. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor if you are allergic or hypersensitive to any component present in the Etoplast 100 mg Injection 5 ml or if you are pregnant, plan to have a baby or are breastfeeding. You should not become pregnant or breastfeed while receiving an etoposide injection. If you become pregnant while on treatment with etoposide, call your doctor. Before taking the Etoplast 100 mg Injection 5 ml, inform your doctor about your medical history and ongoing therapies to rule out any potential adverse effects or interactions. Alcohol should be avoided during treatment with this medicine. You must not drive or operate machinery while receiving Etoplast 100 mg Injection 5 ml.

Uses of Etoplast 100 mg Injection 5 ml

Treatment of Testicular cancer, small cell lung cancer, monoblastic leukaemia (AML M5) and acute myelomonoblastic leukaemia (AML M4)

Directions for Use

Etoplast 100 mg Injection 5 ml will be administered by a qualified healthcare professional; do not self-administer.

Medicinal Benefits

Etoplast 100 mg Injection 5 ml is a chemotherapeutic medication that contains Etoposide. It is primarily used with other medications to treat testicular cancer that has not improved or worsened after treatment with other medications or radiation therapy. Etoposide injection is also used in conjunction with other drugs to treat a certain kind of lung cancer (small cell lung cancer; SCLC). It can also be used to treat monoblastic leukaemia (AML M5) and acute myelomonoblastic leukaemia (AML M4). Etoplast 100 mg Injection 5 ml acts by blocking an enzyme that promotes cancer cell proliferation and induces cell death (apoptosis). As a result, the growth and spread of cancer cells are halted or inhibited.

How Etoplast 100 mg Injection 5 ml Works

Etoplast 100 mg Injection 5 ml contains Etoposide, which is a podophyllotoxin derivative. It works by inhibiting an enzyme responsible for cancer cell proliferation and induces cell death (apoptosis). As a result, the growth and spread of cancer cells are stopped or slowed down.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Etoplast 100 mg Injection 5 ml

  • Myelosuppression (bone marrow activity is decreased)
  • Leucopenia (reduction in the number of white cells in the blood)
  • Thrombocytopenia (deficiency of platelets)
  • Anaemia (deficiency of red cells)
  • Anorexia (lack or loss of appetite for food)
  • Fatigue (extreme tiredness)
  • Drowsiness
  • Nausea
  • Vomiting
  • Alopecia (hair loss)
  • Liver impairment
  • Kidney impairment
  • Leukaemia (cancer of the white blood cell)
  • Hypotension
  • Haemorrhage (loss of blood from damaged blood vessels)
  • Abdominal pain
  • Diarrhoea
  • Stomatitis (inflammation of the mucous membrane)
  • Increased bilirubin levels

What if I have taken an overdose of Etoplast 100 mg Injection 5 ml

As Etoplast 100 mg Injection 5 ml is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Etoplast 100 mg Injection 5 ml may cause severe mucositis and myelotoxicity.

Drug Warnings

Etoplast 100 mg Injection 5 ml is not recommended to use if you are allergic to etoposide, podophyllotoxines or podophyllotoxin-derivatives or any other ingredients of this medicine; If your liver is not working properly; If your bone marrow does not produce enough blood cells; If you are breast-feeding; If you have a weak immune system and you are being vaccinated against yellow fever at the same time. So, inform your doctor about your medical history and ongoing therapies. Etoposide can significantly reduce the number of blood cells in your bone marrow. Before and during your therapy, your doctor will prescribe laboratory testing on a regular basis. A decrease in the number of blood cells in your body might produce symptoms and raise your chance of developing a serious infection or bleeding. If you notice any of the following symptoms, contact your doctor immediately.

Drug-Drug Interactions

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EtoposideRotavirus vaccine
Critical
EtoposideFingolimod
Severe

Drug-Drug Interactions

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EtoposideRotavirus vaccine
Critical
How does the drug interact with Etoplast 100 mg Injection 5 ml:
When the Rotavirus vaccine is used together with Etoplast 100 mg Injection 5 ml, it may not work as well.

How to manage the interaction:
Taking Etoplast 100 mg Injection 5 ml with the Rotavirus vaccine can cause an, please consult doctor before taking it. You may be at risk of acquiring an infection from the vaccination or having a decreased response of the vaccine depending on the dose and length of time you have been on Etoplast 100 mg Injection 5 ml. Do not discontinue any medications without a doctor's advice.
EtoposideFingolimod
Severe
How does the drug interact with Etoplast 100 mg Injection 5 ml:
When Etoplast 100 mg Injection 5 ml is used with Fingolimod, the likelihood or severity of infection may increase.

How to manage the interaction:
Taking Etoplast 100 mg Injection 5 ml with Fingolimod together can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EtoposideInfliximab
Severe
How does the drug interact with Etoplast 100 mg Injection 5 ml:
When Infliximab is taken with Etoplast 100 mg Injection 5 ml, it can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Etoplast 100 mg Injection 5 ml with Infliximab can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
EtoposideCladribine
Severe
How does the drug interact with Etoplast 100 mg Injection 5 ml:
Taking Cladribine with Etoplast 100 mg Injection 5 ml can increase the risk of serious infections.

How to manage the interaction:
Taking Etoplast 100 mg Injection 5 ml with Cladribine together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, or pain while urinating, make sure to contact the doctor right away. Do not stop using any medications without a doctor's advice.
EtoposideTeriflunomide
Severe
How does the drug interact with Etoplast 100 mg Injection 5 ml:
When Etoplast 100 mg Injection 5 ml is used with Teriflunomide, the likelihood or severity of infection may increase.

How to manage the interaction:
Co-administration of Etoplast 100 mg Injection 5 ml with Teriflunomide can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EtoposideIdelalisib
Severe
How does the drug interact with Etoplast 100 mg Injection 5 ml:
When Etoplast 100 mg Injection 5 ml is used with Idelalisib, Idelalisib may increase the blood levels and effects of Etoplast 100 mg Injection 5 ml.

How to manage the interaction:
Taking Etoplast 100 mg Injection 5 ml with Idelalisib together can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
EtoposideGolimumab
Severe
How does the drug interact with Etoplast 100 mg Injection 5 ml:
When Etoplast 100 mg Injection 5 ml is used with Golimumab, the likelihood or severity of infection may increase.

How to manage the interaction:
There may be a possibility of interaction between Etoplast 100 mg Injection 5 ml and Golimumab, but it can be taken if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EtoposideLeflunomide
Severe
How does the drug interact with Etoplast 100 mg Injection 5 ml:
When Etoplast 100 mg Injection 5 ml is used with Leflunomide, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Leflunomide and Etoplast 100 mg Injection 5 ml, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EtoposideNatalizumab
Severe
How does the drug interact with Etoplast 100 mg Injection 5 ml:
Taking Etoplast 100 mg Injection 5 ml with natalizumab, especially taking both simultaneously with little to no time in between, may raise the risk of serious infections.

How to manage the interaction:
Although taking Etoplast 100 mg Injection 5 ml and Natalizumab together can cause an interaction, it can be taken if a doctor has suggested it. However, consult a doctor immediately, if you experience fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. progressive weakening on one side of your body, clumsiness of limbs, visual disturbance, disorientation, or changes in your thinking, memory, or personality. Do not stop using any medications without talking to a doctor.
EtoposideDeferiprone
Severe
How does the drug interact with Etoplast 100 mg Injection 5 ml:
Co-administration of Etoplast 100 mg Injection 5 ml with deferiprone can cause a decrease in white blood cell count, and taking it with Etoplast 100 mg Injection 5 ml, which can similarly alter white blood cell count or bone marrow function, may enhance the risk. As a result, you may be more susceptible to serious infections.

How to manage the interaction:
There may be a possibility of interaction between Etoplast 100 mg Injection 5 ml and Deferiprone, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, and high fibre content. Also, eat small and frequent meals for a speedy recovery.
  • Avoid smoking and alcohol consumption. Also, avoid high fat and cholesterol diet.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Etoplast 100 mg Injection 5 ml Substitute

Substitutes safety advice
  • Etopa 100 mg Injection 5 ml

    38.60per tablet
  • ETOSID 100MG INJECTION 5ML

    34.20per tablet
  • Oncosid 100 Injection 1's

    151.40per tablet
  • Etonco 100 mg Injection 5 ml

    36.00per tablet
  • Adside Injection 5 ml

    36.36per tablet
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Alcohol

Caution

Avoid alcohol consumption while on treatment with Etoplast 100 mg Injection 5 ml.

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Pregnancy

Unsafe

Etoplast 100 mg Injection 5 ml should not be used in pregnant women as it is known to cause fetal damage. Also, a gap of 6 months should be maintained between the last dose of Etoplast 100 mg Injection 5 ml and your next pregnancy. Hence, inform your doctor if you are planning a pregnancy.

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Breast Feeding

Unsafe

Etoplast 100 mg Injection 5 ml should not be used in breastfeeding. Discuss with your doctor if you have any concerns.

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Driving

Caution

Etoplast 100 mg Injection 5 ml may impact your ability to drive or operate machinery, so do not drive or do activities that require your mental alertness after taking this medicine.

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Liver

Caution

Inform your doctor before receiving the Etoplast 100 mg Injection 5 ml if you have had a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please inform your doctor if you have kidney impairment or any concerns.

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Children

Caution

Safety and effectiveness in children have not been established.

FAQs

Etoplast 100 mg Injection 5 ml is used to treat Testicular cancer, small cell lung cancer, monoblastic leukaemia (AML M5) and acute myelomonoblastic leukaemia (AML M4).
Etoplast 100 mg Injection 5 ml contains Etoposide, which is used to treat various types of cancers. It works by inhibiting an enzyme responsible for cancer cell proliferation and induces cell death (apoptosis). As a result, the growth and spread of cancer cells are stopped or slowed down.
While taking Etoplast 100 mg Injection 5 ml, make sure you visit your doctor at all the appointments to ensure that treatment works. Regular monitoring of blood and urine tests and weight checks are required. An effective way of contraception should be used by both men and women while taking the Etoplast 100 mg Injection 5 ml.
Do not stop taking Etoplast 100 mg Injection 5 ml on your own. Take Etoplast 100 mg Injection 5 ml for as long as your doctor prescribes it, depending on your medical condition. Do not hesitate to speak with your doctor if you experience difficulty while taking Etoplast 100 mg Injection 5 ml.
Etoplast 100 mg Injection 5 ml can make you more likely to get infections or may worsen any current infections. Avoid contact with people with infections that may spread to others (such as chickenpox, measles, or flu). Consult your doctor if you have been exposed to an infection or for more details.
The live vaccine may not work while on treatment with Etoplast 100 mg Injection 5 ml. Do not have immunizations/vaccinations without talking to your doctor first. Also, avoid contact with people who recently had immunizations /vaccinations.
Etoposide can cause a significant decrease in the number of blood cells in your bone marrow. Your doctor will order laboratory testing on a regular basis before and during your therapy.
Etoplast 100 mg Injection 5 ml contains Etoposide, which is a podophyllotoxin derivative used to treat cancer of the testicles, lung cancer, Monoblastic leukaemia (AML M5) and acute myelomonoblastic leukaemia (AML M4).
The side effects of Etoplast 100 mg Injection 5 ml include nausea, vomiting, abdominal pain, loss of appetite, temporary hair loss, blood disorders, changes in skin colour, constipation, weakness, dizziness, diarrhoea, and injection site reactions. Consult the doctor if any of these side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - ETO0334

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