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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Last Updated Oct 9, 2024 | 12:36 PM IST
Eptoin 50 mg Injection 5 x 2 ml is an anti-epileptic medication used in the treatment of severe epileptic seizures/fits, to prevent seizures during or after severe head injury and/or neurosurgery. This medicine works by decreasing the abnormal electrical activity in the brain and thus reduces seizures. Common side effects include nausea, vomiting, headache, and constipation.
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Composition

PHENYTOIN-50MG

Manufacturer/Marketer

Abbott India Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Eptoin 50 mg Injection 5 x 2 ml

Eptoin 50 mg Injection 5 x 2 ml belongs to the group of medicines called anti-epileptic agents used to treat severe epileptic seizures/fits (status epilepticus). Also, it is used to prevent seizures during or after severe head injury and/or neurosurgery. Eptoin 50 mg Injection 5 x 2 ml may also be used to treat certain cardiac arrhythmias (irregular heartbeat) caused by certain medicines or in patients who do not respond to conventional anti-arrhythmic medication or cardioversion (a procedure in which low shock is used to restore regular heart rhythm).

Eptoin 50 mg Injection 5 x 2 ml contains 'Phenytoin' that works by decreasing the abnormal electrical activity in the brain. Thereby, Eptoin 50 mg Injection 5 x 2 ml helps prevent and treat epileptic seizures. Eptoin 50 mg Injection 5 x 2 ml treats cardiac arrhythmia by inhibiting rapid inward sodium current and shortening cardiac action potential.

Eptoin 50 mg Injection 5 x 2 ml will be administered by a healthcare professional; do not self-administer. In some cases, Eptoin 50 mg Injection 5 x 2 ml may cause certain common side-effects such as nausea, vomiting, headache, and constipation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while on treatment with Eptoin 50 mg Injection 5 x 2 ml. Avoid driving or operating heavy machinery as Eptoin 50 mg Injection 5 x 2 ml may cause drowsiness and dizziness. Avoid consumption of alcohol as it may cause increased dizziness/drowsiness and might affect the concentration of phenytoin in the blood. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects.

Uses of Eptoin 50 mg Injection 5 x 2 ml

Treatment of Epilepsy/Seizures and Cardiac arrhythmia

Medicinal Benefits

Eptoin 50 mg Injection 5 x 2 ml belongs to the group of medicines called anti-epileptic agents used to treat severe epileptic seizures/fits (status epilepticus). Also, it is used to prevent seizures during or after severe head injury and/or neurosurgery. Eptoin 50 mg Injection 5 x 2 ml works by decreasing the abnormal electrical activity in the brain. Thereby, Eptoin 50 mg Injection 5 x 2 ml helps prevent and treat epileptic seizures. Eptoin 50 mg Injection 5 x 2 ml may also be used to treat certain cardiac arrhythmias (irregular heartbeat) caused by certain medicines or in patients who do not respond to conventional anti-arrhythmic medication or cardioversion (a procedure in which low shock is used to restore regular heart rhythm). Eptoin 50 mg Injection 5 x 2 ml treats cardiac arrhythmia by inhibiting rapid inward sodium current and shortening cardiac action potential.

Directions for Use

Eptoin 50 mg Injection 5 x 2 ml will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Eptoin 50 mg Injection 5 x 2 ml

  • Nausea
  • Vomiting
  • Headache
  • Constipation
  • Abnormal eye movement
  • Slurred speech
  • Confusion
  • Problems with coordination

Drug Warnings

Do not take Eptoin 50 mg Injection 5 x 2 ml if you are allergic to any of its contents. Inform your doctor if you have decreased heart rate, heart block, low blood pressure, heart failure, diabetes, porphyria (blood disorder), heart rhythm problems, alcohol dependence, kidney or liver problems. Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while on treatment with Eptoin 50 mg Injection 5 x 2 ml. Do not drive or operate heavy machinery as Eptoin 50 mg Injection 5 x 2 ml may cause drowsiness and dizziness. Avoid consumption of alcohol as it may cause increased dizziness/drowsiness and might affect the concentration of phenytoin in the blood.

Drug Interactions

Drug-Drug Interactions: Eptoin 50 mg Injection 5 x 2 ml may have interaction with anti-HIV drugs (delavirdine), painkillers (aspirin, acetaminophen), blood thinners (warfarin, clopidogrel), anti-convulsant (gabapentin, pregabalin), anti-depressant (quetiapine), diuretic (furosemide), cholesterol-lowering agent (atorvastatin), a drug used to treat thyroid deficiency (levothyroxine), supplements (ergocalciferol, cholecalciferol).

Drug-Food Interactions: Do not take Eptoin 50 mg Injection 5 x 2 ml with St. John's wort (an antidepressant herbal supplement).

Drug-Disease Interactions: Inform your doctor if you have/had decreased heart rate, heart block, low blood pressure, heart failure, diabetes, or porphyria (blood disorder).

Drug-Drug Interactions Checker List

  • DELAVIRDINE
  • ASPIRIN
  • ACETAMINOPHEN
  • WARFARIN
  • CLOPIDOGREL
  • GABAPENTIN
  • PREGABALIN
  • QUETIAPINE
  • FUROSEMIDE
  • ATORVASTATIN
  • LEVOTHYROXINE
  • ERGOCALCIFEROL
  • CHOLECALCIFEROL

Habit Forming

No

Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for people with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Exercise, meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Install an alarm or emergency device to get assistance during a seizure attack.
  • Have a seizure response plan, this helps those around you know what to do.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health as it can help in reducing seizure activity.

Special Advise

Consult your doctor immediately if you have suicidal thoughts such as harming or killing yourself.

Disease/Condition Glossary

Epilepsy/Seizures: Seizures, also known as fits or convulsions, is a single occurrence of abnormal electrical activity in the brain, whereas epilepsy is a chronic neurological disorder characterized by recurrent seizures. The possible causes of epilepsy include traumatic brain injury, scarring on the brain after a brain injury, high fever, stroke, vascular diseases, lack of oxygen to the brain, brain tumours, and genetic disorders. Symptoms include mood changes, anxiousness, nausea, dizziness, weakness, headache, muscle jerking, spasms, loss of balance, teeth clenching, rapid blinking or eye movements, biting the tongue, confusion, and loss of consciousness.

Cardiac arrhythmia: Cardiac arrhythmia is a condition in which the heartbeats are abnormal or irregular. It occurs when the electrical signals in the heart do not work properly. Symptoms may include palpitations (a feeling as if the heart is pounding), chest pain, fainting, and dizziness.

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Eptoin 50 mg Injection 5 x 2 ml to prevent unpleasant side-effects. It might also affect the concentration of phenytoin in the blood.

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Pregnancy

Caution

Consult your doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe Eptoin 50 mg Injection 5 x 2 ml only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding while on treatment with Eptoin 50 mg Injection 5 x 2 ml. Please consult your doctor if you have any concerns.

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Driving

Unsafe

Eptoin 50 mg Injection 5 x 2 ml may cause dizziness and drowsiness. Avoid driving or operating machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed. Eptoin 50 mg Injection 5 x 2 ml should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Eptoin 50 mg Injection 5 x 2 ml should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Eptoin 50 mg Injection 5 x 2 ml can be given to children if prescribed by the doctor.

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - EPT0008

Author Details

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FAQs

Eptoin 50 mg Injection 5 x 2 ml belongs to the group of medicines called anti-epileptic agents used to treat severe epileptic seizures/fits (status epilepticus), and prevent seizures during or after severe head injury and/or neurosurgery. Eptoin 50 mg Injection 5 x 2 ml may also be used to treat certain cardiac arrhythmias (irregular heartbeat) caused by certain medicines or in patients who do not respond to conventional anti-arrhythmic medication or cardioversion.
Eptoin 50 mg Injection 5 x 2 ml works by controlling overactivity of the brain that causes seizures (fits). Thereby, Eptoin 50 mg Injection 5 x 2 ml helps in controlling epileptic fits.
Eptoin 50 mg Injection 5 x 2 ml can make hormonal contraceptives less effective. Talk to your doctor about using non-hormonal contraceptives like condoms and diaphragm with spermicide to prevent pregnancy.
Eptoin 50 mg Injection 5 x 2 ml may cause hyperglycemia (high blood glucose levels). So, inform your doctor if you have diabetes.
Eptoin 50 mg Injection 5 x 2 ml may affect the metabolism of vitamin D, which could cause osteomalacia. Inform your doctor if you have bone problems.
Eptoin 50 mg Injection 5 x 2 ml might increase blood sugar levels and decrease blood calcium levels, folic acid, phosphate, and vitamin D levels. Inform the person doing the tests that you are taking Eptoin 50 mg Injection 5 x 2 ml.

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