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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Epsolin Injection 7 x 2 ml is an anti-epileptic medication used in the treatment of severe epileptic seizures/fits, to prevent seizures during or after severe head injury and/or neurosurgery. This medicine works by decreasing the abnormal electrical activity in the brain and thus reduces seizures. Common side effects include nausea, vomiting, headache, and constipation.
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Composition :

PHENYTOIN-50MG

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Epsolin Injection 7 x 2 ml

Epsolin Injection 7 x 2 ml belongs to the group of medicines called anti-epileptic agents used to treat severe epileptic seizures/fits (status epilepticus). Also, it is used to prevent seizures during or after severe head injury and/or neurosurgery. Epsolin Injection 7 x 2 ml may also be used to treat certain cardiac arrhythmias (irregular heartbeat) caused by certain medicines or in patients who do not respond to conventional anti-arrhythmic medication or cardioversion (a procedure in which low shock is used to restore regular heart rhythm).

Epsolin Injection 7 x 2 ml contains 'Phenytoin' that works by decreasing the abnormal electrical activity in the brain. Thereby, Epsolin Injection 7 x 2 ml helps prevent and treat epileptic seizures. Epsolin Injection 7 x 2 ml treats cardiac arrhythmia by inhibiting rapid inward sodium current and shortening cardiac action potential.

Epsolin Injection 7 x 2 ml will be administered by a healthcare professional; do not self-administer. In some cases, Epsolin Injection 7 x 2 ml may cause certain common side-effects such as nausea, vomiting, headache, and constipation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while on treatment with Epsolin Injection 7 x 2 ml . Avoid driving or operating heavy machinery as Epsolin Injection 7 x 2 ml may cause drowsiness and dizziness. Avoid consumption of alcohol as it may cause increased dizziness/drowsiness and might affect the concentration of phenytoin in the blood. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects.

Uses of Epsolin Injection 7 x 2 ml

Treatment of Epilepsy/Seizures and Cardiac arrhythmia

Directions for Use

Epsolin Injection 7 x 2 ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Epsolin Injection 7 x 2 ml belongs to the group of medicines called anti-epileptic agents used to treat severe epileptic seizures/fits (status epilepticus). Also, it is used to prevent seizures during or after severe head injury and/or neurosurgery. Epsolin Injection 7 x 2 ml works by decreasing the abnormal electrical activity in the brain. Thereby, Epsolin Injection 7 x 2 ml helps prevent and treat epileptic seizures. Epsolin Injection 7 x 2 ml may also be used to treat certain cardiac arrhythmias (irregular heartbeat) caused by certain medicines or in patients who do not respond to conventional anti-arrhythmic medication or cardioversion (a procedure in which low shock is used to restore regular heart rhythm). Epsolin Injection 7 x 2 ml treats cardiac arrhythmia by inhibiting rapid inward sodium current and shortening cardiac action potential.

How Epsolin Injection 7 x 2 ml Works

Epsolin Injection 7 x 2 ml contains 'Phenytoin' that works by decreasing the abnormal electrical activity in the brain. Thereby, Epsolin Injection 7 x 2 ml helps prevent and treat epileptic seizures. Epsolin Injection 7 x 2 ml treats cardiac arrhythmia by inhibiting rapid inward sodium current and shortening cardiac action potential.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Epsolin Injection 7 x 2 ml

  • Nausea
  • Vomiting
  • Headache
  • Constipation
  • Abnormal eye movement
  • Slurred speech
  • Confusion
  • Problems with coordination

What if I have taken an overdose of Epsolin Injection 7 x 2 ml

Epsolin Injection 7 x 2 ml is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. The neurotoxic effects vary in severity depending on the concentration and can include lethargy, vomiting, ataxia, slurred speech, mild nystagmus, coma, and death. Ironically, phenytoin can cause seizures at very high concentrations. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

Do not take Epsolin Injection 7 x 2 ml if you are allergic to any of its contents. Inform your doctor if you have decreased heart rate, heart block, low blood pressure, heart failure, diabetes, porphyria (blood disorder), heart rhythm problems, alcohol dependence, kidney or liver problems. Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while on treatment with Epsolin Injection 7 x 2 ml . Do not drive or operate heavy machinery as Epsolin Injection 7 x 2 ml may cause drowsiness and dizziness. Avoid consumption of alcohol as it may cause increased dizziness/drowsiness and might affect the concentration of phenytoin in the blood.

Drug-Drug Interactions

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PhenytoinRilpivirine
Critical
PhenytoinIsavuconazole
Critical

Drug-Drug Interactions

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PhenytoinRilpivirine
Critical
How does the drug interact with Epsolin Injection 7 x 2 ml :
Using rilpivirine together with Epsolin Injection 7 x 2 ml may significantly reduce the blood levels of rilpivirine.

How to manage the interaction:
Taking Rilpivirine with Epsolin Injection 7 x 2 ml is not recommended, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
PhenytoinIsavuconazole
Critical
How does the drug interact with Epsolin Injection 7 x 2 ml :
Co-administration of Epsolin Injection 7 x 2 ml and Isavuconazole may significantly reduce the blood levels of Isavuconazole, which may make Isavuconazole less effective in treating your condition.

How to manage the interaction:
Taking Isavuconazole with Epsolin Injection 7 x 2 ml is not recommended as it can cause an interaction, consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
PhenytoinLurasidone
Critical
How does the drug interact with Epsolin Injection 7 x 2 ml :
Using lurasidone together with Epsolin Injection 7 x 2 ml may significantly decrease the blood levels of lurasidone.

How to manage the interaction:
Using lurasidone with Epsolin Injection 7 x 2 ml is not recommended, it can be taken if a doctor has prescribed it. Consult a doctor, if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
PhenytoinVenetoclax
Critical
How does the drug interact with Epsolin Injection 7 x 2 ml :
Using venetoclax together with Epsolin Injection 7 x 2 ml may significantly reduce the blood levels of venetoclax leading to decreased effectiveness of venetoclax in treating in your condition.

How to manage the interaction:
Taking Epsolin Injection 7 x 2 ml with Venetoclax is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
PhenytoinRanolazine
Critical
How does the drug interact with Epsolin Injection 7 x 2 ml :
Using ranolazine together with Epsolin Injection 7 x 2 ml may significantly reduce the blood levels of ranolazine leading to dreceased effectiveness of ranolazine in treating your condition.

How to manage the interaction:
Taking Epsolin Injection 7 x 2 ml with Ranolazine is not recommended. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
PhenytoinCimetidine
Critical
How does the drug interact with Epsolin Injection 7 x 2 ml :
Using Epsolin Injection 7 x 2 ml together with Cimetidin may increase the effects of Epsolin Injection 7 x 2 ml .

How to manage the interaction:
Taking Epsolin Injection 7 x 2 ml with Cimetidine can cause an interaction, consult a doctor before taking it. Contact a doctor if you experience twitching eye movements, slurred speech, loss of balance, tremors, muscle stiffness or weakness, nausea, vomiting, feeling light-headed, fainting, and slow or shallow breathing. Do not stop using any medications without talking to a doctor.
PhenytoinCimetidine
Critical
How does the drug interact with Epsolin Injection 7 x 2 ml :
Using Epsolin Injection 7 x 2 ml together with cimetidine may increase the effects of Epsolin Injection 7 x 2 ml .

How to manage the interaction:
Taking Epsolin Injection 7 x 2 ml with Cimetidine is not recommended, it can be taken if prescribed by the doctor. Contact a doctor, if you experience twitching eye movements, slurred speech, loss of balance, tremors, muscle stiffness or weakness, nausea, vomiting, feeling light-headed, fainting, and slow or shallow breathing. Do not stop using any medications without talking to a doctor.
PhenytoinPraziquantel
Critical
How does the drug interact with Epsolin Injection 7 x 2 ml :
Using praziquantel together with Epsolin Injection 7 x 2 ml may significantly reduce the blood levels of praziquantel leading decreased effectiveness.

How to manage the interaction:
Taking Epsolin Injection 7 x 2 ml with Praziquantelcan is not recommended as it cause an interaction, it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
PhenytoinCeritinib
Critical
How does the drug interact with Epsolin Injection 7 x 2 ml :
Taking ceritinib with Epsolin Injection 7 x 2 ml may significantly reduce the blood levels and effectiveness of Ceritinib.

How to manage the interaction:
Taking Epsolin Injection 7 x 2 ml with Ceritinib is not recommended as it can cause an interaction, it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
PhenytoinDolutegravir
Severe
How does the drug interact with Epsolin Injection 7 x 2 ml :
Taking dolutegravir with Epsolin Injection 7 x 2 ml may significantly reduce the blood levels of dolutegravir, which may make the medication less effective in treating infections.

How to manage the interaction:
Although taking Dolutegravir and Epsolin Injection 7 x 2 ml together can result in an interaction, they can be taken together if prescribed by a doctor. Do not discontinue using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for people with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Exercise, meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Install an alarm or emergency device to get assistance during a seizure attack.
  • Have a seizure response plan, this helps those around you know what to do.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health as it can help in reducing seizure activity.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Epsolin Injection 7 x 2 ml Substitute

Substitutes safety advice
  • Eptoin 50 Tablet 150's

    0.83per tablet
  • Eptoin 50 mg Injection 5 x 2 ml

    11.98per tablet
  • Tpsolin 50Mg Inj 2Ml

    by AYUR

    5.08per tablet
  • Dilantin 50 mg Capsule 100's

    1.38per tablet
  • Protoin 50 Tablet 10's

    0.73per tablet
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Epsolin Injection 7 x 2 ml to prevent unpleasant side-effects. It might also affect the concentration of phenytoin in the blood.

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Pregnancy

Caution

Consult your doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe Epsolin Injection 7 x 2 ml only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding while on treatment with Epsolin Injection 7 x 2 ml . Please consult your doctor if you have any concerns.

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Driving

Unsafe

Epsolin Injection 7 x 2 ml may cause dizziness and drowsiness. Avoid driving or operating machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed. Epsolin Injection 7 x 2 ml should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Epsolin Injection 7 x 2 ml should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Epsolin Injection 7 x 2 ml can be given to children if prescribed by the doctor.

FAQs

Epsolin Injection 7 x 2 ml belongs to the group of medicines called anti-epileptic agents used to treat severe epileptic seizures/fits (status epilepticus), and prevent seizures during or after severe head injury and/or neurosurgery. Epsolin Injection 7 x 2 ml may also be used to treat certain cardiac arrhythmias (irregular heartbeat) caused by certain medicines or in patients who do not respond to conventional anti-arrhythmic medication or cardioversion.
Epsolin Injection 7 x 2 ml works by controlling overactivity of the brain that causes seizures (fits). Thereby, Epsolin Injection 7 x 2 ml helps in controlling epileptic fits.
Epsolin Injection 7 x 2 ml can make hormonal contraceptives less effective. Talk to your doctor about using non-hormonal contraceptives like condoms and diaphragm with spermicide to prevent pregnancy.
Epsolin Injection 7 x 2 ml may cause hyperglycemia (high blood glucose levels). So, inform your doctor if you have diabetes.
Epsolin Injection 7 x 2 ml may affect the metabolism of vitamin D, which could cause osteomalacia. Inform your doctor if you have bone problems.
Epsolin Injection 7 x 2 ml might increase blood sugar levels and decrease blood calcium levels, folic acid, phosphate, and vitamin D levels. Inform the person doing the tests that you are taking Epsolin Injection 7 x 2 ml .

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Other Info - EPS0002

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