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  3. EPOTREND 10K INJECTION

EPOTREND 10K INJECTION , Pack of 1 INJECTION
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

EPOTREND 10K INJECTION is used in the treatment of chronic anaemia and anaemic states seen in kidney disease, cancers, patients on chemotherapy, and bone marrow disorders. This medicine works by stimulating the bone marrow to produce more red blood cells, thereby correcting any low blood counts and anaemia. You may experience common side effects like vomiting, diarrhoea, fever, and nasal congestion.

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Composition :

RECOMBINANT HUMAN ERYTHROPOIETIN ALFA-10000IU

Manufacturer/Marketer :

Anthem Bio Pharma

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About EPOTREND 10K INJECTION

EPOTREND 10K INJECTION belongs to the group of hormones used in the treatment of chronic anaemia and anaemic states seen in kidney disease, cancers, patients on chemotherapy, bone marrow disorders, and those due to undergo major bone surgery. Anaemia refers to low blood counts due to a deficiency of the blood component haemoglobin, resulting in a reduced oxygen-carrying capacity of the blood.

EPOTREND 10K INJECTION contains Recombinant Human Erythropoietin Alfa, which works by stimulating the bone marrow to produce more red blood cells, thereby correcting low blood counts and anaemia.

In some cases, EPOTREND 10K INJECTION may cause specific common side effects such as vomiting, diarrhoea, fever, and nasal congestion. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if you experience these side effects consistently.

Please inform the doctor of your detailed medical history, including hypertension, heart disease, heart attack, stroke, epilepsy, cancer, liver disease, thromboembolism, porphyria and/or pure red cell aplasia (where the bone marrow cannot produce enough RBCs). Consult your doctor before taking EPOTREND 10K INJECTION during pregnancy and nursing. Store this medicine at 2°C-8°C. Do not freeze.

Uses of EPOTREND 10K INJECTION

EPOTREND 10K INJECTION is used to treat anemia caused by chronic kidney illness, cancer, and HIV infection. It is also used in perioperative care for some surgical patients.

Directions for Use

EPOTREND 10K INJECTION will be administered by a healthcare professional. In some cases, depending on the need, you may have to self-inject EPOTREND 10K INJECTION . Do not self-inject without proper training. After an initial treatment, your doctor/nurse may train you on administering the injection.

Medicinal Benefits

EPOTREND 10K INJECTION is a blood hormone. It contains Recombinant Human Erythropoietin Alfa used to treat anaemia caused by chronic diseases and anaemia related to kidney disease, cancers, bone marrow disorders, chemotherapy, children and adults on dialysis, and in those due to undergo major bone surgery. EPOTREND 10K INJECTION stimulates the bone marrow to produce more red blood cells. In addition, it also corrects any dysregulated erythropoiesis (RBC formation) and remedies the formation of any defunct precursors of RBC’s, paving the way for healthy red blood cell production. Clinically, EPOTREND 10K INJECTION causes a direct increase in haemoglobin values and reduces the rates and requirement of blood transfusion.

How EPOTREND 10K INJECTION Works

EPOTREND 10K INJECTION contains Recombinant Human Erythropoietin Alfa that works by stimulating the bone marrow to produce more red blood cells, thereby correcting any low blood counts and anaemia.

Storage

Store in a cool and dry place away from sunlight

Side Effects of EPOTREND 10K INJECTION

  • Diarrhoea
  • Vomiting
  • Stomach upset
  • Fever
  • Nasal congestion

What if I have taken an overdose of EPOTREND 10K INJECTION

Overdose of EPOTREND 10K INJECTION increases blood viscosity and the risk of thrombosis by raising haemoglobin levels to dangerously high levels. Seek immediate medical help if you get an overdose of this medicine.

Drug Warnings

Inform the doctor if you have an allergy to any of its components. Proceed with caution in case of a latex allergy. Please inform the doctor of your detailed medical history, including hypertension, heart disease, myocardial infarction, stroke, epilepsy, head and neck cancers, liver disease, thromboembolism, porphyria and/or pure red cell aplasia (where the bone marrow cannot produce enough RBCs). Inform your doctor of any medicines you may be taking especially if you are on any immunosuppressants, blood thinners or blood stimulants. Please consult your doctor before taking EPOTREND 10K INJECTION during pregnancy and nursing.

Drug-Drug Interactions

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ErythropoietinCarfilzomib
Severe
ErythropoietinPomalidomide
Severe

Drug-Drug Interactions

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ErythropoietinCarfilzomib
Severe
How does the drug interact with Epotrend 10k Injection:
Carfilzomib can cause serious blood clots and taking it alongside Epotrend 10k Injection may enhance the risk.

How to manage the interaction:
Co-administration of Epotrend 10k Injection with Carfilzomib can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience chest pain, breathing difficulty, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ErythropoietinPomalidomide
Severe
How does the drug interact with Epotrend 10k Injection:
Pomalidomide can cause serious blood clots and taking it alongside Epotrend 10k Injection may enhance the risk.

How to manage the interaction:
Co-administration of Epotrend 10k Injection with Pomalidomide can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience chest pain, breathing difficulty, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
ErythropoietinLenalidomide
Severe
How does the drug interact with Epotrend 10k Injection:
Combining Epotrend 10k Injection with Lenalidomide can increase the risk of Thrombosis(formation of a blood clot ).

How to manage the interaction:
Although there is an interaction between Epotrend 10k Injection and Lenalidomide, it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
ErythropoietinThalidomide
Severe
How does the drug interact with Epotrend 10k Injection:
Taking thalidomide with Epotrend 10k Injection may increase the risk or severity of thromboembolism(a circulating blood clot that gets stuck and causes an obstruction).

How to manage the interaction:
Although taking Epotrend 10k Injection and thalidomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • As nausea and vomiting may occur using EPOTREND 10K INJECTION , make sure to take it on light, small meals. 
  • To promote blood production, eat red fruits and vegetables, such as apples, pomegranates, dry fruits, beans, and nuts.
  • Avoid caffeine and alcohol as these can precipitate bleeding.
  • Take care of your mental health. Stress is a huge factor that can cause excessive bleeding. Make sure you meditate daily in the morning.
  • Yoga has also proven very effective in preventing excessive blood loss. The butterfly pose is one of the best poses for treating heavy periods.
  • Make sure you drink a lot of water and keep yourself hydrated. Fluid intake helps flush out toxins.

Habit Forming

No

Therapeutic Class

BLOOD DERIVATIVES

EPOTREND 10K INJECTION Substitute

Substitutes safety advice

  • Epofit 10000IU Injection 1 ml

    by Others

    ₹1984.50per tablet

  • Anfoe 10000IU Injection 1 ml

    by Others

    ₹1983.60per tablet

  • TRANSFER 10000IU INJECTION

    by Others

    ₹1983.60per tablet

  • Zyrop 10000 Injection 1's

    by Others

    ₹1984.50per tablet

  • Repomia 10000 Injection 1 ml

    by AYUR

    ₹1936.00per tablet

Product Substitutes

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Alcohol

Caution

There is not enough literature to explain the effects of alcohol. Consult your doctor if you have any concerns.

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Pregnancy

Caution

If you are pregnant or planning to become pregnant, inform your doctor. Your doctor will weigh the benefits against the risks.

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Breast Feeding

Caution

Let your doctor know if you are a nursing mother before taking EPOTREND 10K INJECTION ; your doctor will decide whether breastfeeding mothers can use EPOTREND 10K INJECTION or not.

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Driving

Caution

It's unclear whether EPOTREND 10K INJECTION affects driving abilities, so don't drive or operate machinery if you're having trouble concentrating or reacting.

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Liver

Caution

EPOTREND 10K INJECTION should be used with caution in patients suffering from liver diseases. Please inform your doctor before receiving it.

bannner image

Kidney

Caution

EPOTREND 10K INJECTION should be used with caution in patients suffering from kidney diseases. Please inform your doctor before receiving it.

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Children

Safe if prescribed

EPOTREND 10K INJECTION can be used in children in prescribed paediatric doses.

FAQs

EPOTREND 10K INJECTION belongs to the group of hormones used in the treatment of chronic anaemia and anaemic states seen in kidney disease, cancers, patients on chemotherapy, bone marrow disorders and in those due to undergo major bone surgery.

EPOTREND 10K INJECTION works by stimulating the bone marrow to produce healthy red blood cells (RBC’s) and thus enhances blood production.

Consult your doctor before taking iron supplements along with EPOTREND 10K INJECTION as they might increase the effectiveness of EPOTREND 10K INJECTION when taken together.

EPOTREND 10K INJECTION might affect other treatments or tests. Therefore, inform the doctor/lab assistant that you are taking EPOTREND 10K INJECTION .

Not commonly. However, cases of Steven Johnson’s syndrome and Toxic Epidermal Necrosis (TEN), have been reported in rare instances. Consult your doctor immediately if you notice symptoms such as reddish-circular patches, skin peeling, fever, flu, ulcers of throat, mouth, nose, eyes or genitals.

EPOTREND 10K INJECTION may cause blood clots (deep vein thrombosis and embolism). Consult your doctor if you experience symptoms such as breathlessness, chest pain, painful swelling and redness in the legs.

The common side effects of EPOTREND 10K INJECTION may include vomiting, diarrhoea, fever, and nasal congestion. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects consistently.

EPOTREND 10K INJECTION contains Recombinant Human Erythropoietin Alfa. A hormone medication that stimulates the bone marrow to produce more red blood cells, correcting low blood counts and anaemia.

Don't stop taking your medication just because you're feeling better! This is a crucial moment in your recovery. Stopping too soon can lead to incomplete recovery and the return of symptoms. Instead, report your progress to your doctor and follow their advice. They will guide you on how to safely taper off the medication, if necessary, monitor for any potential side effects, and ensure the infection is fully cleared.

EPOTREND 10K INJECTION is usually given to you by a healthcare professional through an Intravenous(veins). In some cases, you may need to go to a local clinic or learn to self-inject, but only after proper training from a doctor or nurse.

You can store EPOTREND 10K INJECTION in the refrigerator or a cool, dry place away from sunlight. Do not freeze. Use at room temperature only.

Store EPOTREND 10K INJECTION in a refrigerator or in a cool, dry place away from sunlight. Keep it out of reach of children. Do not freeze it.

Taking more than the prescribed dose doesn't provide extra relief; instead, it may increase the risk of adverse effects, potentially harming your health.

Don't use EPOTREND 10K INJECTION if the solution is expired, frozen, or allergic to it. It's also not recommended for those with hypersensitivity disorders, thromboembolism, and red cell aplasia. Pregnant or breastfeeding women or children unless the doctor suggests it. Always consult your doctor before using.

EPOTREND 10K INJECTION can be used in children under a doctor's guidance and in prescribed pediatric doses.

EPOTREND 10K INJECTION may increase blood pressure or worsen existing high blood pressure, especially in patients with kidney failure, due to the rapid increase in red blood cells. Inform your doctor beforehand if you have any blood pressure issues. Your doctor will adjust the dose if the benefits outweigh the risks.

Country of origin

INDIA

Manufacturer/Marketer address

No 49, Canara Bank Road, Bommasandra Industrial Area, Phase 1, Hosur Road, Bangalore 560 099, Karnataka, India.
Other Info - EPO0067

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Keep Refrigerated. Do not freeze.Prepaid payment required.

Author Details

Doctor imageDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Doctor imageDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Apr 11, 2025 | 12:04 PM IST

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Reference

  1. https://www.webmd.com/drugs/2/drug-1023/epoetin-alfa-injection/details
  2. https://www.medicines.org.uk/emc/files/pil.3442.pdf
  3. https://www.sciencedirect.com/topics/medicine-and-dentistry/recombinant-erythropoietin
  4. https://pubmed.ncbi.nlm.nih.gov/12735213/
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