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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Epofer 10000 Injection is used in the treatment of chronic anaemia and anaemic states seen in kidney disease, cancers, patients on chemotherapy, and bone marrow disorders. This medicine works by stimulating the bone marrow to produce more red blood cells, thereby correcting any low blood counts and anaemia. You may experience common side effects like vomiting, diarrhoea, fever, and nasal congestion.

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Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Epofer 10000 Injection

Epofer 10000 Injection belongs to the group of hormones used in the treatment of chronic anaemia and anaemic states seen in kidney disease, cancers, patients on chemotherapy, bone marrow disorders, and those due to undergo major bone surgery. Anaemia refers to low blood counts due to a deficiency of the blood component haemoglobin, resulting in a reduced oxygen-carrying capacity of the blood.

Epofer 10000 Injection contains Recombinant Human Erythropoietin Alfa, which works by stimulating the bone marrow to produce more red blood cells, thereby correcting low blood counts and anaemia.

In some cases, Epofer 10000 Injection may cause specific common side effects such as vomiting, diarrhoea, fever, and nasal congestion. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if you experience these side effects consistently.

Please inform the doctor of your detailed medical history, including hypertension, heart disease, heart attack, stroke, epilepsy, cancer, liver disease, thromboembolism, porphyria and/or pure red cell aplasia (where the bone marrow cannot produce enough RBCs). Consult your doctor before taking Epofer 10000 Injection during pregnancy and nursing. Store this medicine at 2°C-8°C. Do not freeze.

Uses of Epofer 10000 Injection

Epofer 10000 Injection is used to treat anemia caused by chronic kidney illness, cancer, and HIV infection. It is also used in perioperative care for some surgical patients.

Directions for Use

Epofer 10000 Injection will be administered by a healthcare professional. In some cases, depending on the need, you may have to self-inject Epofer 10000 Injection. Do not self-inject without proper training. After an initial treatment, your doctor/nurse may train you on administering the injection.

Medicinal Benefits

Epofer 10000 Injection is a blood hormone. It contains Recombinant Human Erythropoietin Alfa used to treat anaemia caused by chronic diseases and anaemia related to kidney disease, cancers, bone marrow disorders, chemotherapy, children and adults on dialysis, and in those due to undergo major bone surgery. Epofer 10000 Injection stimulates the bone marrow to produce more red blood cells. In addition, it also corrects any dysregulated erythropoiesis (RBC formation) and remedies the formation of any defunct precursors of RBC’s, paving the way for healthy red blood cell production. Clinically, Epofer 10000 Injection causes a direct increase in haemoglobin values and reduces the rates and requirement of blood transfusion.

How Epofer 10000 Injection Works

Epofer 10000 Injection contains Recombinant Human Erythropoietin Alfa that works by stimulating the bone marrow to produce more red blood cells, thereby correcting any low blood counts and anaemia.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Epofer 10000 Injection

  • Diarrhoea
  • Vomiting
  • Stomach upset
  • Fever
  • Nasal congestion

What if I have taken an overdose of Epofer 10000 Injection

Overdose of Epofer 10000 Injection increases blood viscosity and the risk of thrombosis by raising haemoglobin levels to dangerously high levels. Seek immediate medical help if you get an overdose of this medicine.

Drug Warnings

Inform the doctor if you have an allergy to any of its components. Proceed with caution in case of a latex allergy. Please inform the doctor of your detailed medical history, including hypertension, heart disease, myocardial infarction, stroke, epilepsy, head and neck cancers, liver disease, thromboembolism, porphyria and/or pure red cell aplasia (where the bone marrow cannot produce enough RBCs). Inform your doctor of any medicines you may be taking especially if you are on any immunosuppressants, blood thinners or blood stimulants. Please consult your doctor before taking Epofer 10000 Injection during pregnancy and nursing.

Diet & Lifestyle Advise

  • As nausea and vomiting may occur using Epofer 10000 Injection, make sure to take it on light, small meals. 
  • To promote blood production, eat red fruits and vegetables, such as apples, pomegranates, dry fruits, beans, and nuts.
  • Avoid caffeine and alcohol as these can precipitate bleeding.
  • Take care of your mental health. Stress is a huge factor that can cause excessive bleeding. Make sure you meditate daily in the morning.
  • Yoga has also proven very effective in preventing excessive blood loss. The butterfly pose is one of the best poses for treating heavy periods.
  • Make sure you drink a lot of water and keep yourself hydrated. Fluid intake helps flush out toxins.

Habit Forming

No

Therapeutic Class

BLOOD DERIVATIVES

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Alcohol

Caution

There is not enough literature to explain the effects of alcohol. Consult your doctor if you have any concerns.

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Pregnancy

Caution

If you are pregnant or planning to become pregnant, inform your doctor. Your doctor will weigh the benefits against the risks.

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Breast Feeding

Caution

Let your doctor know if you are a nursing mother before taking Epofer 10000 Injection; your doctor will decide whether breastfeeding mothers can use Epofer 10000 Injection or not.

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Driving

Caution

It's unclear whether Epofer 10000 Injection affects driving abilities, so don't drive or operate machinery if you're having trouble concentrating or reacting.

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Liver

Caution

Epofer 10000 Injection should be used with caution in patients suffering from liver diseases. Please inform your doctor before receiving it.

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Kidney

Caution

Epofer 10000 Injection should be used with caution in patients suffering from kidney diseases. Please inform your doctor before receiving it.

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Children

Safe if prescribed

Epofer 10000 Injection can be used in children in prescribed paediatric doses.

FAQs

Epofer 10000 Injection belongs to the group of hormones used in the treatment of chronic anaemia and anaemic states seen in kidney disease, cancers, patients on chemotherapy, bone marrow disorders and in those due to undergo major bone surgery.

Epofer 10000 Injection works by stimulating the bone marrow to produce healthy red blood cells (RBC’s) and thus enhances blood production.

Consult your doctor before taking iron supplements along with Epofer 10000 Injection as they might increase the effectiveness of Epofer 10000 Injection when taken together.

Epofer 10000 Injection might affect other treatments or tests. Therefore, inform the doctor/lab assistant that you are taking Epofer 10000 Injection.

Not commonly. However, cases of Steven Johnson’s syndrome and Toxic Epidermal Necrosis (TEN), have been reported in rare instances. Consult your doctor immediately if you notice symptoms such as reddish-circular patches, skin peeling, fever, flu, ulcers of throat, mouth, nose, eyes or genitals.

Epofer 10000 Injection may cause blood clots (deep vein thrombosis and embolism). Consult your doctor if you experience symptoms such as breathlessness, chest pain, painful swelling and redness in the legs.

The common side effects of Epofer 10000 Injection may include vomiting, diarrhoea, fever, and nasal congestion. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects consistently.

Epofer 10000 Injection contains Recombinant Human Erythropoietin Alfa. A hormone medication that stimulates the bone marrow to produce more red blood cells, correcting low blood counts and anaemia.

Don't stop taking your medication just because you're feeling better! This is a crucial moment in your recovery. Stopping too soon can lead to incomplete recovery and the return of symptoms. Instead, report your progress to your doctor and follow their advice. They will guide you on how to safely taper off the medication, if necessary, monitor for any potential side effects, and ensure the infection is fully cleared.

Epofer 10000 Injection is usually given to you by a healthcare professional through an Intravenous(veins). In some cases, you may need to go to a local clinic or learn to self-inject, but only after proper training from a doctor or nurse.

You can store Epofer 10000 Injection in the refrigerator or a cool, dry place away from sunlight. Do not freeze. Use at room temperature only.

Store Epofer 10000 Injection in a refrigerator or in a cool, dry place away from sunlight. Keep it out of reach of children. Do not freeze it.

Taking more than the prescribed dose doesn't provide extra relief; instead, it may increase the risk of adverse effects, potentially harming your health.

Don't use Epofer 10000 Injection if the solution is expired, frozen, or allergic to it. It's also not recommended for those with hypersensitivity disorders, thromboembolism, and red cell aplasia. Pregnant or breastfeeding women or children unless the doctor suggests it. Always consult your doctor before using.

Epofer 10000 Injection can be used in children under a doctor's guidance and in prescribed pediatric doses.

Epofer 10000 Injection may increase blood pressure or worsen existing high blood pressure, especially in patients with kidney failure, due to the rapid increase in red blood cells. Inform your doctor beforehand if you have any blood pressure issues. Your doctor will adjust the dose if the benefits outweigh the risks.

Country of origin

India

Manufacturer/Marketer address

A €“ 504, Shapath-4, B/S Hotel Crowne Plaza, Opp. Karnavati Club, S. G. Highway ,Ahmedabad 380 051 Gujarat
Other Info - EPO0059

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