apollo
0
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
ENDOXAN N INJECTION 1GM is used to treat Cancer. It contains 'Cyclophosphamide' that works by stopping or slowing the growth of cancer cells in the body. Thereby, It helps treat Cancer. Additionally, It is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients. It suppresses the body's immune system, thereby helping treat nephrotic syndrome. Common side effects of ENDOXAN N INJECTION 1GM are nausea, vomiting, stomatitis (inflamed and sore mouth), weakness, malaise (general discomfort), fever, leukopenia (low white blood cell count), and alopecia (hair loss).
Read more
rxMedicinePrescription drug

Whats That

tooltip
Consult Doctor

Manufacturer/Marketer :

German Remedies Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About ENDOXAN N INJECTION 1GM

ENDOXAN N INJECTION 1GM belongs to the group of medicines called alkylating agents used to treat malignant diseases such as Hodgkin's disease, mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma, Burkitt's lymphoma, leukaemia,  neuroblastoma, retinoblastoma, adenocarcinoma of the ovary, mycosis fungoides, Ewing's sarcoma, small cell lung cancer, advanced/metastatic neuroblastoma and breast carcinoma. Additionally, ENDOXAN N INJECTION 1GM is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients.
 
ENDOXAN N INJECTION 1GM contains 'Cyclophosphamide' that works by stopping or slowing the growth of cancer cells in the body. Thereby, ENDOXAN N INJECTION 1GM helps treat cancer. ENDOXAN N INJECTION 1GM suppresses the body's immune system and helps treat nephrotic syndrome.
 
In some cases, ENDOXAN N INJECTION 1GM may cause nausea, vomiting, stomatitis (inflamed and sore mouth), weakness, malaise (general discomfort), fever, leukopenia (low white blood cell count), and alopecia (hair loss). You are advised to talk to your doctor if the side effects persist or worsen.
 
Consult your doctor if you are pregnant, planning pregnancy, or breastfeeding. ENDOXAN N INJECTION 1GM may cause dizziness, so drive only if you are alert. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of ENDOXAN N INJECTION 1GM

Treatment of Cancer and nephrotic syndrome (kidney disease)

Directions for Use

ENDOXAN N INJECTION 1GM will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

ENDOXAN N INJECTION 1GM belongs to the group of medicines called alkylating agents used to treat malignant diseases such as Hodgkin's disease (cancer of the lymphatic system), mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma (cancer of plasma cells), Burkitt's lymphoma, leukaemia (blood cancer), neuroblastoma (cancer commonly found in the adrenal glands), retinoblastoma (eye cancer), adenocarcinoma of the ovary, mycosis fungoides, Ewing's sarcoma (cancer in and around the bones), small cell lung cancer, advanced/metastatic neuroblastoma and breast carcinoma. ENDOXAN N INJECTION 1GM works by stopping or slowing the growth of cancer cells in the body. Thereby, ENDOXAN N INJECTION 1GM helps treat cancer. Additionally, ENDOXAN N INJECTION 1GM is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients. ENDOXAN N INJECTION 1GM suppresses the body's immune system, thereby helping treat nephrotic syndrome.

How ENDOXAN N INJECTION 1GM Works

ENDOXAN N INJECTION 1GM contains 'Cyclophosphamide' that works by stopping or slowing the growth of cancer cells in the body. Thereby, ENDOXAN N INJECTION 1GM helps treat cancer. ENDOXAN N INJECTION 1GM suppresses the body's immune system and helps treat nephrotic syndrome.

Storage

Store in a cool and dry place away from sunlight

Side Effects of ENDOXAN N INJECTION 1GM

  • Nausea
  • Vomiting
  • Stomatitis (inflamed and sore mouth)
  • Weakness
  • Malaise (general discomfort)
  • Fever
  • Leukopenia (low white blood cell count)
  • Alopecia (hair loss)

What if I have taken an overdose of ENDOXAN N INJECTION 1GM

As ENDOXAN N INJECTION 1GM is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Do not take ENDOXAN N INJECTION 1GM if you are allergic to any of its components. Inform your doctor if you have acute infections, bone marrow depression, urinary tract infections, urinary outflow/obstruction, liver or kidney problems, or urinary or respiratory symptoms. Consult your doctor if you are pregnant or breastfeeding. ENDOXAN N INJECTION 1GM may cause myelosuppression, immunosuppression, bone marrow failure, and infections; consult your doctor if you have any concerns.

Drug-Drug Interactions

verifiedApollotooltip
CyclophosphamideNalidixic acid
Critical
CyclophosphamideCidofovir
Critical

Drug-Drug Interactions

Login/Sign Up

CyclophosphamideNalidixic acid
Critical
How does the drug interact with ENDOXAN N INJECTION 1GM:
Co-administration of Nalidixic acid with ENDOXAN N INJECTION 1GM may cause an increase in the risk of side effects.

How to manage the interaction:
Co-administration of ENDOXAN N INJECTION 1GM and Nalidixic acid can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like bruising or bleeding, unusual weakness, nausea, stomach pain, low fever, or loss of appetite, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
CyclophosphamideCidofovir
Critical
How does the drug interact with ENDOXAN N INJECTION 1GM:
Co-administration of ENDOXAN N INJECTION 1GM and Cidofovir may increase the risk of kidney problems.

How to manage the interaction:
Taking Cyclophosphamine with Cidofovir is not recommended, please consult your doctor before taking it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not discontinue any medications without consulting a doctor
CyclophosphamideTenofovir alafenamide
Severe
How does the drug interact with ENDOXAN N INJECTION 1GM:
Co-administration of Tenofovir alafenamide may cause kidney problems, and combining it with ENDOXAN N INJECTION 1GM may increase the risk.

How to manage the interaction:
Although there is a possible interaction, ENDOXAN N INJECTION 1GM can be taken with Tenofovir alafenamide if prescribed by the doctor. Consult the doctor if you develop signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop any medication without consulting a doctor.
CyclophosphamideFingolimod
Severe
How does the drug interact with ENDOXAN N INJECTION 1GM:
Taking Fingolimod's ability to suppress the immune system may be enhanced by ENDOXAN N INJECTION 1GM.

How to manage the interaction:
Although taking ENDOXAN N INJECTION 1GM and Fingolimod together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, it's important to contact a doctor right away - a serious infection, problems, high body temperature, feeling cold, loose stools, a painful throat, body discomfort, difficulty breathing, losing weight, or experiencing pain or discomfort while urinating. Do not stop using any medications without a doctor's advice.
CyclophosphamideInfliximab
Severe
How does the drug interact with ENDOXAN N INJECTION 1GM:
When ENDOXAN N INJECTION 1GM is taken with Infliximab, it can increase the risk or severity of developing serious infections.

How to manage the interaction:
Although taking Infliximab and ENDOXAN N INJECTION 1GM together can cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
CyclophosphamideVoclosporin
Severe
How does the drug interact with ENDOXAN N INJECTION 1GM:
Co-administration of ENDOXAN N INJECTION 1GM with Voclosporin can increase the risk of kidney damage.

How to manage the interaction:
Although there is a possible interaction between ENDOXAN N INJECTION 1GM and Voclosporin, you can take these medicines together if prescribed by a doctor. It's important to keep an eye on how much you pee. Some other signs to watch out for are feeling sick, throwing up, not wanting to eat, gaining or losing weight suddenly, holding onto fluids, having a fever or chills, having diarrhea or a sore throat, feeling weak or dizzy, being confused, having trouble breathing, feeling pain or a burning sensation when you pee, or having an irregular heartbeat. Do not stop using any medications without talking to a doctor.
CyclophosphamideCladribine
Severe
How does the drug interact with ENDOXAN N INJECTION 1GM:
The combined use of Cladribine with ENDOXAN N INJECTION 1GM can increase the risk and severity of side effects.

How to manage the interaction:
Co-administration of Cladribine with ENDOXAN N INJECTION 1GM can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, contact a doctor right away. These symptoms include complications, infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate. Do not discontinue any medications without consulting a doctor.
CyclophosphamideTofacitinib
Severe
How does the drug interact with ENDOXAN N INJECTION 1GM:
Taking ENDOXAN N INJECTION 1GM with Tofacitinib may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction, ENDOXAN N INJECTION 1GM can be taken with Tofacitinib if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
CyclophosphamideTenofovir disoproxil
Severe
How does the drug interact with ENDOXAN N INJECTION 1GM:
Coadministration of Tenofovir disoproxil with ENDOXAN N INJECTION 1GM may increase the risk of developing kidney problems.

How to manage the interaction:
Although there is a possible interaction, ENDOXAN N INJECTION 1GM can be taken with Tenofovir disoproxil if prescribed by the doctor. Consult the doctor if you experience signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medication without consulting a doctor.
CyclophosphamideTeriflunomide
Severe
How does the drug interact with ENDOXAN N INJECTION 1GM:
Co-administration of ENDOXAN N INJECTION 1GM with Teriflunomide can increase the risk of side effects.

How to manage the interaction:
Although taking ENDOXAN N INJECTION 1GM and Teriflunomide together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any symptoms like fever, chills, sore throat, or muscle aches, it's best to contact a doctor right away. Other symptoms to watch out for include diarrhea, shortness of breath, weight loss, or pain during urination. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs, and spices in your food.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

ENDOXAN N INJECTION 1GM Substitute

Substitutes safety advice
  • Uniphos 1000 Injection 1's

    126.90per tablet
  • Phoxelon 1000mg Injection 1's

    123.75per tablet
  • Cyphos 1000 mg Injection 1's

    120.60per tablet
  • Phosmid 1000 mg Injection 1's

    73.80per tablet
  • Cyclosted 1000 Injection 1's

    180.00per tablet
bannner image

Alcohol

Caution

You are recommended to avoid alcohol consumption as it may worsen the risk of cyclophosphamide-induced nausea and vomiting.

bannner image

Pregnancy

Caution

It is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving ENDOXAN N INJECTION 1GM. Your doctor may prescribe this medicine only if the benefits outweigh the risks.

bannner image

Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving ENDOXAN N INJECTION 1GM. Avoid breastfeeding during treatment with ENDOXAN N INJECTION 1GM and for one week after the last dose.

bannner image

Driving

Caution

ENDOXAN N INJECTION 1GM may cause dizziness. Do not drive or operate heavy machinery until you are alert.

bannner image

Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving ENDOXAN N INJECTION 1GM. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

bannner image

Kidney

Caution

If you have a history of kidney diseases, inform your doctor before receiving ENDOXAN N INJECTION 1GM. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

bannner image

Children

Consult your doctor

Please consult your doctor. Your doctor will with the benefits and risks before prescribing this medicine based on your child's medical condition.

FAQs

ENDOXAN N INJECTION 1GM is used to treat Cancer and nephrotic syndrome (kidney disease).
ENDOXAN N INJECTION 1GM works by stopping or slowing down the growth of cancer cells in the body. Thereby, ENDOXAN N INJECTION 1GM helps treat cancer. ENDOXAN N INJECTION 1GM suppresses the body's immune system and helps treat nephrotic syndrome.
ENDOXAN N INJECTION 1GM might impair fertility and interfere with oogenesis (development of ovum) and spermatogenesis (development of sperm). Please consult your doctor if you have any concerns.
Men should avoid fathering a child during the treatment and for six months following discontinuation of therapy.
ENDOXAN N INJECTION 1GM might interfere with normal wound healing. Therefore, be cautious while handling sharp objects. Consult your doctor if you notice unusual bleeding or bruising or if the wounds do not heal properly.

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads, Ahmedabad – 380015, Gujarat, India.
Other Info - END0004

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
icon image

Keep Refrigerated. Do not freeze.Prepaid payment required.

whatsapp Floating Button