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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:36 PM IST
Oncomide 1000mg Injection is used to treat Cancer. It contains 'Cyclophosphamide' that works by stopping or slowing the growth of cancer cells in the body. Thereby, It helps treat Cancer. Additionally, It is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients. It suppresses the body's immune system, thereby helping treat nephrotic syndrome. Common side effects of Oncomide 1000mg Injection are nausea, vomiting, stomatitis (inflamed and sore mouth), weakness, malaise (general discomfort), fever, leukopenia (low white blood cell count), and alopecia (hair loss).
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Manufacturer/Marketer

Khandelwal Laboratories Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Oncomide 1000mg Injection

Oncomide 1000mg Injection belongs to the group of medicines called alkylating agents used to treat malignant diseases such as Hodgkin's disease, mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma, Burkitt's lymphoma, leukaemia,  neuroblastoma, retinoblastoma, adenocarcinoma of the ovary, mycosis fungoides, Ewing's sarcoma, small cell lung cancer, advanced/metastatic neuroblastoma and breast carcinoma. Additionally, Oncomide 1000mg Injection is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients.
 
Oncomide 1000mg Injection contains 'Cyclophosphamide' that works by stopping or slowing the growth of cancer cells in the body. Thereby, Oncomide 1000mg Injection helps treat cancer. Oncomide 1000mg Injection suppresses the body's immune system and helps treat nephrotic syndrome.
 
In some cases, Oncomide 1000mg Injection may cause nausea, vomiting, stomatitis (inflamed and sore mouth), weakness, malaise (general discomfort), fever, leukopenia (low white blood cell count), and alopecia (hair loss). You are advised to talk to your doctor if the side effects persist or worsen.
 
Consult your doctor if you are pregnant, planning pregnancy, or breastfeeding. Oncomide 1000mg Injection may cause dizziness, so drive only if you are alert. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Oncomide 1000mg Injection

Treatment of Cancer and nephrotic syndrome (kidney disease)

Medicinal Benefits

Oncomide 1000mg Injection belongs to the group of medicines called alkylating agents used to treat malignant diseases such as Hodgkin's disease (cancer of the lymphatic system), mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma (cancer of plasma cells), Burkitt's lymphoma, leukaemia (blood cancer), neuroblastoma (cancer commonly found in the adrenal glands), retinoblastoma (eye cancer), adenocarcinoma of the ovary, mycosis fungoides, Ewing's sarcoma (cancer in and around the bones), small cell lung cancer, advanced/metastatic neuroblastoma and breast carcinoma. Oncomide 1000mg Injection works by stopping or slowing the growth of cancer cells in the body. Thereby, Oncomide 1000mg Injection helps treat cancer. Additionally, Oncomide 1000mg Injection is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients. Oncomide 1000mg Injection suppresses the body's immune system, thereby helping treat nephrotic syndrome.

Directions for Use

Oncomide 1000mg Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Oncomide 1000mg Injection

  • Nausea
  • Vomiting
  • Stomatitis (inflamed and sore mouth)
  • Weakness
  • Malaise (general discomfort)
  • Fever
  • Leukopenia (low white blood cell count)
  • Alopecia (hair loss)

Drug Warnings

Do not take Oncomide 1000mg Injection if you are allergic to any of its components. Inform your doctor if you have acute infections, bone marrow depression, urinary tract infections, urinary outflow/obstruction, liver or kidney problems, or urinary or respiratory symptoms. Consult your doctor if you are pregnant or breastfeeding. Oncomide 1000mg Injection may cause myelosuppression, immunosuppression, bone marrow failure, and infections; consult your doctor if you have any concerns.

Drug Interactions

Drug-Drug Interactions: Oncomide 1000mg Injection may have interaction with protease inhibitors, ACE inhibitors, immunomodulators (natalizumab), chemotherapy agents (paclitaxel), thiazide diuretics, anti-HIV (zidovudine), antiarrhythmics (amiodarone), anti-fungal (amphotericin B), NSAID (indomethacin), immunosuppressant (azathioprine), alkylating agents (busulfan).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have acute infections, bone marrow depression, urinary tract infections, urinary outflow or obstruction.

Drug-Drug Interactions Checker List

  • NATALIZUMAB
  • PACLITAXEL
  • ZIDOVUDINE
  • AMIODARONE
  • AMPHOTERICIN B
  • INDOMETHACIN
  • AZATHIOPRINE
  • BUSULFAN

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs, and spices in your food.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.

Special Advise

  • Monitoring of complete blood count whilst on treatment with Oncomide 1000mg Injection is advised.
  • Women of childbearing potential must use highly effective contraception during treatment and for up to 1 year after the last dose.
  • Male patients who are sexually active with a female partner of child-bearing potential must use condoms during treatment and for up to 6 months after the last dose.

Disease/Condition Glossary

Cancer: It occurs due to mutations in genes that regulate cell growth. The mutations cause the cells to divide and multiply in an uncontrolled manner leading to the formation of tumours. The most common cancer treatment methods are surgery, chemotherapy, radiotherapy, bone marrow (stem cell) transplantation, immunotherapy and targeted drug therapy.

Nephrotic syndrome: It is a kidney disorder in which the body excretes too much protein in the urine. Symptoms include foamy urine, weight gain, and swelling around the eyes and in the ankles and feet.

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Alcohol

Caution

You are recommended to avoid alcohol consumption as it may worsen the risk of cyclophosphamide-induced nausea and vomiting.

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Pregnancy

Caution

It is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Oncomide 1000mg Injection. Your doctor may prescribe this medicine only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving Oncomide 1000mg Injection. Avoid breastfeeding during treatment with Oncomide 1000mg Injection and for one week after the last dose.

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Driving

Caution

Oncomide 1000mg Injection may cause dizziness. Do not drive or operate heavy machinery until you are alert.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Oncomide 1000mg Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a history of kidney diseases, inform your doctor before receiving Oncomide 1000mg Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Consult your doctor

Please consult your doctor. Your doctor will with the benefits and risks before prescribing this medicine based on your child's medical condition.

Country of origin

India

Manufacturer/Marketer address

711 712, Modi Tower, 98 Nehru Place, New Delhi- 110019, India
Other Info - ON90149

Author Details

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FAQs

Oncomide 1000mg Injection is used to treat Cancer and nephrotic syndrome (kidney disease).
Oncomide 1000mg Injection works by stopping or slowing down the growth of cancer cells in the body. Thereby, Oncomide 1000mg Injection helps treat cancer. Oncomide 1000mg Injection suppresses the body's immune system and helps treat nephrotic syndrome.
Oncomide 1000mg Injection might impair fertility and interfere with oogenesis (development of ovum) and spermatogenesis (development of sperm). Please consult your doctor if you have any concerns.
Men should avoid fathering a child during the treatment and for six months following discontinuation of therapy.
Oncomide 1000mg Injection might interfere with normal wound healing. Therefore, be cautious while handling sharp objects. Consult your doctor if you notice unusual bleeding or bruising or if the wounds do not heal properly.

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