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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Enal-H Tablet is used to treat hypertension (high blood pressure). It contains Enalapril and Hydrochlorothiazide, which decreases the constriction and narrowing of blood vessels leading to high blood pressure. Thereby, it widens and relaxes blood vessels. Also, it removes excess water and certain salts such as sodium and potassium from the blood. This reduces the fluid volume circulating through blood vessels and lower high blood pressure. In some cases, you may experience dizziness, weakness, blurred vision, nausea, headache, orthostatic hypotension (low blood pressure when standing up from sitting or lying position), high cholesterol or uric acid levels, electrolyte imbalance, diarrhoea, chest pain, fast heartbeat, changes in taste or stomach pain. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

East West Pharma India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Enal-H Tablet

Enal-H Tablet belongs to a class of medication called 'anti-hypertensive' primarily used to treat hypertension (high blood pressure). Hypertension is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

Enal-H Tablet is a combination of two drugs: Enalapril (angiotensin-converting enzyme inhibitor) and Hydrochlorothiazide (diuretic). Enalapril belongs to the class angiotensin-converting enzyme (ACE) inhibitors that work by blocking an angiotensin-converting enzyme which decreases the production of angiotensin II in the body that causes constriction and narrowing of blood vessels leading to high blood pressure. Thereby, it widens and relaxes blood vessels. Hydrochlorothiazide belongs to diuretics (water tablets) that work by increasing the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels. Thus, together they lower high blood pressure.

Take Enal-H Tablet as prescribed. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience dizziness, weakness, blurred vision, nausea, headache, orthostatic hypotension (low blood pressure when standing up from sitting or lying position), high cholesterol or uric acid levels, electrolyte imbalance, diarrhoea, chest pain, fast heartbeat, changes in taste or stomach pain. Most of these side effects of Enal-H Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

Enal-H Tablet is not recommended for pregnant women, especially in second and third trimesters as it may cause serious harm to the baby. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking Enal-H Tablet . Avoid potassium supplements with Enal-H Tablet as it may lead to high potassium levels in the blood. If you have asthma, diabetes, low blood pressure, difficulty in urination, gout, blood disorders, systemic lupus erythematosus (an autoimmune disease), scleroderma (hardening and tightening of skin), cerebrovascular disease (a condition affecting blood flow to the brain), have a history of angioedema (swelling under the skin) or skin cancer, kidney, liver or heart problems inform your doctor before taking Enal-H Tablet .

Uses of Enal-H Tablet

Treatment of Hypertension (high blood pressure)

Directions for Use

Take Enal-H Tablet with or without food as advised by a doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Enal-H Tablet is a combination of two drugs, namely: Enalapril and Hydrochlorothiazide. Enalapril belongs to the class angiotensin-converting enzyme (ACE) inhibitors that work by blocking an angiotensin-converting enzyme which decreases the production of angiotensin II in the body causes constriction and narrowing of blood vessels leading to high blood pressure. Thereby, it widens and relaxes blood vessels. Hydrochlorothiazide is a diuretic (water tablet) that increases the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels. Thus, together they lower high blood pressure.

How Enal-H Tablet Works

Enal-H Tablet is a combination of two drugs: Enalapril (angiotensin-converting enzyme inhibitor) and Hydrochlorothiazide (diuretic). Enalapril belongs to the class angiotensin-converting enzyme (ACE) inhibitors that work by blocking an angiotensin-converting enzyme which decreases the production of angiotensin II in the body that causes constriction and narrowing of blood vessels leading to high blood pressure. Thereby, it widens and relaxes blood vessels. Hydrochlorothiazide belongs to diuretics (water tablets) that work by increasing the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels. Thus, together they lower high blood pressure.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Enal-H Tablet

  • Dizziness
  • Weakness
  • Blurred vision
  • Nausea
  • Headache
  • Orthostatic hypotension (low blood pressure when standing up from lying or sitting position)
  • High cholesterol or uric acid levels
  • Electrolyte imbalance
  • Diarrhoea
  • Chest pain
  • Fast heartbeat
  • Changes in taste
  • Stomach pain

What if I have taken an overdose of Enal-H Tablet

Do not take more than the prescribed dose of Enal-H Tablet as it may cause overdose. The symptoms of overdose include light-headedness, dizziness or fainting. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

If you are known to be allergic to Enal-H Tablet or any other medicines, please tell your doctor. Enal-H Tablet is not recommended for pregnant women, especially in second and third trimesters as it may cause serious harm to the baby. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking Enal-H Tablet . It is advised to complete the full course of medication and do not suddenly stop taking Enal-H Tablet as it may cause recurring symptoms or worsen the condition. Avoid potassium supplements with Enal-H Tablet as it may lead to high potassium levels in the blood. If you are about to under any surgery, receive anesthetics, LDL apheresis treatment (cholesterol removal from blood using a machine), or desensitization treatment, inform your doctor that you are taking Enal-H Tablet . If you have asthma, diabetes, low blood pressure, difficulty in urination, gout, blood disorders, systemic lupus erythematosus (an autoimmune disease), scleroderma (hardening and tightening of skin), cerebrovascular disease (a condition affecting blood flow to the brain), have a history of angioedema (swelling under the skin) or skin cancer, kidney, liver or heart problems inform your doctor before taking Enal-H Tablet . 

Drug-Drug Interactions

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EnalaprilAliskiren
Critical
HydrochlorothiazideDofetilide
Critical

Drug-Drug Interactions

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EnalaprilAliskiren
Critical
How does the drug interact with Enal-H Tablet:
Using aliskiren together with Enal-H Tablet may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood.

How to manage the interaction:
Taking Enal-H Tablet with aliskiren is not recommended, but it can be taken together if your doctor advises. However, contact your doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, or feelings of heaviness in the legs. Do not stop taking any medications without consulting a doctor.
HydrochlorothiazideDofetilide
Critical
How does the drug interact with Enal-H Tablet:
Taking Dofetilide and Enal-H Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Dofetilide and Enal-H Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
HydrochlorothiazideCisapride
Critical
How does the drug interact with Enal-H Tablet:
Taking Cisapride and Enal-H Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Cisapride and Enal-H Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
EnalaprilMipomersen
Severe
How does the drug interact with Enal-H Tablet:
When mipomersen is used with other drugs that can potentially damage the liver, like Enal-H Tablet, the risk of liver issues increases.

How to manage the interaction:
Although taking Enal-H Tablet and Mipomersen together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms - joint pain, swelling, skin rash, itching, fatigue, abdominal pain, or dark urine - immediately contact your doctor. Do not stop using any medications without a doctor's advice.
EnalaprilEprosartan
Severe
How does the drug interact with Enal-H Tablet:
Taking Enal-H Tablet together with eprosartan may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Enal-H Tablet and Eprosartan together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you experience nausea, vomiting, weakness, tingling of the hands and feet, and feelings of heaviness in the legs, contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
EnalaprilLithium
Severe
How does the drug interact with Enal-H Tablet:
Taking Lithium with Enal-H Tablet may significantly increase the blood levels of lithium.

How to manage the interaction:
Co-administration of Enal-H Tablet with Lithium can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience drowsiness, dizziness, loose stools, vomiting, muscle weakness, shaking of hands and legs, excessive thirst, and increased urination. Do not discontinue any medications without consulting a doctor.
EnalaprilTriamterene
Severe
How does the drug interact with Enal-H Tablet:
Taking Enal-H Tablet together with triamterene may increase the levels of potassium in your blood (hyperkalemia), especially if you are dehydrated or have kidney disease or diabetes.

How to manage the interaction:
Although taking Enal-H Tablet with Triamterene may result in an interaction, they can be taken together if your doctor prescribes it. However, contact your doctor immediately if you experience weakness, confusion, numbness or tingling. Do not discontinue any medication without consulting your doctor.
EnalaprilPotassium gluconate
Severe
How does the drug interact with Enal-H Tablet:
Taking Potassium gluconate with Enal-H Tablet can increase the risk of high potassium levels in the blood.

How to manage the interaction:
Although there is a possible interaction between Enal-H Tablet and Potassium gluconate, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms, such as nausea, vomiting, weakness, tingling in your hands and feet, or feelings of heaviness in your legs - it's important to contact your doctor immediately. Do not stop using any medications without a doctor's advice.
EnalaprilOlmesartan medoxomil
Severe
How does the drug interact with Enal-H Tablet:
Using Enal-H Tablet together with olmesartan medoxomil may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Co-administration of Enal-H Tablet with Olmesartan medoxomil may lead to interaction, but it can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, and feelings of heaviness in the legs. Do not discontinue any medications without consulting a doctor.
EnalaprilPotassium iodide
Severe
How does the drug interact with Enal-H Tablet:
Taking Enal-H Tablet with Potassium iodide increases the potassium levels in the blood, which may lead to hyperkalemia. In severe cases, hyperkalemia may lead to muscular paralysis, kidney damage, and cardiac problems. The risk is increased if you are elderly, dehydrated, or have a history of kidney or heart disease.

How to manage the interaction:
Although taking Enal-H Tablet together with Potassium iodide may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, coconut and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.

Drug-Food Interactions

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ENALAPRIL-5MG+HYDROCHLOROTHIAZIDE-12.5MGPotassium rich foods
Moderate

Drug-Food Interactions

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ENALAPRIL-5MG+HYDROCHLOROTHIAZIDE-12.5MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Consumption of potassium rich food while on the treatment with Enal-H Tablet can lead to weakness, confusion, numbness of tingling sensation in hands or legs, or slow or rapid heartbeat. Avoid or limit consumption of potassium rich food while on the treatment with Enal-H Tablet.

Diet & Lifestyle Advise

  • Maintain a low salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavor to the food.
  • Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day.
  • Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time for yourself to relax and do activities that you enjoy.
  • Maintain a diet that is rich in vegetables, fruits, whole grains, and low-fat dairy products.
  • Try to include heart-healthy omega 3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil which may help in lowering high blood pressure.
  • Quit smoking and avoid the consumption of alcohol.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Enal-H Tablet Substitute

Substitutes safety advice
  • Envas-H Tablet 10's

    by Others

    10.26per tablet
  • Enalet H 5mg/12.5mg Tablet

    by Others

    6.53per tablet
  • Enace D 5 Tablet 30's

    by Others

    7.25per tablet
  • ENACE D 5MG TABLET 30'S

    by Others

    7.25per tablet
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Alcohol

Unsafe

Avoid alcohol consumption with Enal-H Tablet as it may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness or headache.

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Pregnancy

Unsafe

Please consult a doctor if you are pregnant. Enal-H Tablet is not recommended for pregnant women, especially in the second and third trimesters as it may cause birth defects or serious harm to the baby.

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Breast Feeding

Unsafe

Enal-H Tablet may be excreted in human milk. Therefore, Enal-H Tablet is not recommended for breastfeeding mothers as it may be unsafe for the baby. However, please consult a doctor.

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Driving

Caution

Enal-H Tablet may cause dizziness or tiredness in some people. Therefore, avoid driving if you feel dizzy or tired after taking Enal-H Tablet .

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Liver

Caution

Enal-H Tablet should be given with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Enal-H Tablet if you have severe liver problems.

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Kidney

Caution

Enal-H Tablet should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Enal-H Tablet if you have severe kidney problems.

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Children

Unsafe

It is not recommended for children as the safety and effectiveness were not established.

FAQs

Enal-H Tablet is used to treat hypertension (high blood pressure).

Enal-H Tablet contains Enalapril and Hydrochlorothiazide. Enalapril belongs to the class angiotensin-converting enzyme (ACE) inhibitors that work by blocking an angiotensin-converting enzyme which decreases the production of angiotensin II in the body that causes constriction and narrowing of blood vessels leading to high blood pressure. Thereby, it widens and relaxes blood vessels. Hydrochlorothiazide is a diuretic (water tablet) that increases the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels. Thus, together they lower high blood pressure.

You are not recommended to take furosemide with Enal-H Tablet as co-administration of these two medicines may increase the risk of low blood pressure. However, if you experience dizziness, reduced heart rate, headache or fainting, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted to use safely.

It is advised to inform your doctor if you have had skin cancer or develop an unexpected skin lesion as hydrochlorothiazide in Enal-H Tablet may increase the risk of certain types of skin and lip cancer especially when taken in high doses for a long period. Therefore, it is recommended to protect the skin from UV rays and sun exposure while taking Enal-H Tablet .

No, you are not recommended to take potassium supplements with Enal-H Tablet as it may increase the levels of potassium in the blood (hyperkalaemia). However, please consult a doctor before taking other medicines with Enal-H Tablet .

If you have any kidney problems, it is advised to inform your doctor before taking Enal-H Tablet as Enal-H Tablet may worsen kidney functioning if there is any existing kidney problem. However, if you experience unexplained weight gain, swelling in feet, ankles or hands, please consult your doctor immediately.

You are not recommended to take more than the prescribed dose of Enal-H Tablet as it may cause Enal-H Tablet overdose resulting in symptoms such as low blood pressure, cough, nausea, dizziness, cramps, drowsiness, fast or slow heartbeat, anxiety, increased urination or difficulty in urination. However, if you experience any of these symptoms while taking Enal-H Tablet , please consult a doctor immediately.Enal-H Tablet belongs to a class of medication called 'anti-hypertensive' primarily used to treat hypertension (high blood pressure). Hypertension is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

Country of origin

India

Manufacturer/Marketer address

6, Nandalal Bose Sarani,Kolkata -700071.
Other Info - ENA0042

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