apollo
0
Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:39 PM IST
ENACE D 5MG TABLET is used to treat hypertension (high blood pressure). It contains Enalapril and Hydrochlorothiazide, which decreases the constriction and narrowing of blood vessels leading to high blood pressure. Thereby, it widens and relaxes blood vessels. Also, it removes excess water and certain salts such as sodium and potassium from the blood. This reduces the fluid volume circulating through blood vessels and lower high blood pressure. In some cases, you may experience dizziness, weakness, blurred vision, nausea, headache, orthostatic hypotension (low blood pressure when standing up from sitting or lying position), high cholesterol or uric acid levels, electrolyte imbalance, diarrhoea, chest pain, fast heartbeat, changes in taste or stomach pain. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
Read more
Prescription drug

Whats That

tooltip
Prescription drug
 Trailing icon
Consult Doctor

Manufacturer/Marketer

Nicholas Piramal India Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About ENACE D 5MG TABLET

ENACE D 5MG TABLET belongs to a class of medication called 'anti-hypertensive' primarily used to treat hypertension (high blood pressure). Hypertension is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

ENACE D 5MG TABLET is a combination of two drugs: Enalapril (angiotensin-converting enzyme inhibitor) and Hydrochlorothiazide (diuretic). Enalapril belongs to the class angiotensin-converting enzyme (ACE) inhibitors that work by blocking an angiotensin-converting enzyme which decreases the production of angiotensin II in the body that causes constriction and narrowing of blood vessels leading to high blood pressure. Thereby, it widens and relaxes blood vessels. Hydrochlorothiazide belongs to diuretics (water tablets) that work by increasing the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels. Thus, together they lower high blood pressure.

Take ENACE D 5MG TABLET as prescribed. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience dizziness, weakness, blurred vision, nausea, headache, orthostatic hypotension (low blood pressure when standing up from sitting or lying position), high cholesterol or uric acid levels, electrolyte imbalance, diarrhoea, chest pain, fast heartbeat, changes in taste or stomach pain. Most of these side effects of ENACE D 5MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

ENACE D 5MG TABLET is not recommended for pregnant women, especially in second and third trimesters as it may cause serious harm to the baby. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking ENACE D 5MG TABLET . Avoid potassium supplements with ENACE D 5MG TABLET as it may lead to high potassium levels in the blood. If you have asthma, diabetes, low blood pressure, difficulty in urination, gout, blood disorders, systemic lupus erythematosus (an autoimmune disease), scleroderma (hardening and tightening of skin), cerebrovascular disease (a condition affecting blood flow to the brain), have a history of angioedema (swelling under the skin) or skin cancer, kidney, liver or heart problems inform your doctor before taking ENACE D 5MG TABLET .

Uses of ENACE D 5MG TABLET

Treatment of Hypertension (high blood pressure)

Medicinal Benefits

ENACE D 5MG TABLET is a combination of two drugs, namely: Enalapril and Hydrochlorothiazide. Enalapril belongs to the class angiotensin-converting enzyme (ACE) inhibitors that work by blocking an angiotensin-converting enzyme which decreases the production of angiotensin II in the body causes constriction and narrowing of blood vessels leading to high blood pressure. Thereby, it widens and relaxes blood vessels. Hydrochlorothiazide is a diuretic (water tablet) that increases the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels. Thus, together they lower high blood pressure.

Directions for Use

Take ENACE D 5MG TABLET with or without food as advised by a doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of ENACE D 5MG TABLET

  • Dizziness
  • Weakness
  • Blurred vision
  • Nausea
  • Headache
  • Orthostatic hypotension (low blood pressure when standing up from lying or sitting position)
  • High cholesterol or uric acid levels
  • Electrolyte imbalance
  • Diarrhoea
  • Chest pain
  • Fast heartbeat
  • Changes in taste
  • Stomach pain

Drug Warnings

If you are known to be allergic to ENACE D 5MG TABLET or any other medicines, please tell your doctor. ENACE D 5MG TABLET is not recommended for pregnant women, especially in second and third trimesters as it may cause serious harm to the baby. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking ENACE D 5MG TABLET . It is advised to complete the full course of medication and do not suddenly stop taking ENACE D 5MG TABLET as it may cause recurring symptoms or worsen the condition. Avoid potassium supplements with ENACE D 5MG TABLET as it may lead to high potassium levels in the blood. If you are about to under any surgery, receive anesthetics, LDL apheresis treatment (cholesterol removal from blood using a machine), or desensitization treatment, inform your doctor that you are taking ENACE D 5MG TABLET . If you have asthma, diabetes, low blood pressure, difficulty in urination, gout, blood disorders, systemic lupus erythematosus (an autoimmune disease), scleroderma (hardening and tightening of skin), cerebrovascular disease (a condition affecting blood flow to the brain), have a history of angioedema (swelling under the skin) or skin cancer, kidney, liver or heart problems inform your doctor before taking ENACE D 5MG TABLET . 

Drug Interactions

Drug-Drug Interaction: ENACE D 5MG TABLET may have interaction with pain killers (aspirin), antidepressants (duloxetine, fluoxetine, sertraline), water tablets (hydrochlorothiazide, furosemide), anticonvulsants (pregabalin), medicines used to lower high blood pressure (metoprolol, amlodipine), bronchodilators (albuterol, salmeterol), vitamin (cholecalciferol).

Drug- Food Interaction: ENACE D 5MG TABLET may interact with potassium salt substitutes and potassium supplements resulting in hyperkalemia (high levels of potassium in the blood) and may cause severe adverse effects such as irregular heartbeat, muscle paralysis, and kidney failure. Also, avoid intake of potassium-rich foods such as coconut water, bananas, and broccoli.

Drug-Disease Interaction: If you have asthma, diabetes, low blood pressure, difficulty in urination, gout, blood disorders, systemic lupus erythematosus (an autoimmune disease), scleroderma  (hardening and tightening of skin), cerebrovascular disease (a condition affecting blood flow to the brain), have a history of angioedema (swelling under the skin) or skin cancer, kidney, liver or heart problems inform your doctor before taking ENACE D 5MG TABLET .

Drug-Drug Interactions Checker List

  • ASPIRIN
  • DULOXETINE
  • FLUOXETINE
  • SERTRALINE
  • HYDROCHLOROTHIAZIDE
  • FUROSEMIDE
  • PREGABALIN
  • METOPROLOL
  • AMLODIPINE
  • ALBUTEROL
  • SALMETEROL
  • CHOLECALCIFEROL

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a low salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavor to the food.
  • Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day.
  • Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time for yourself to relax and do activities that you enjoy.
  • Maintain a diet that is rich in vegetables, fruits, whole grains, and low-fat dairy products.
  • Try to include heart-healthy omega 3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil which may help in lowering high blood pressure.
  • Quit smoking and avoid the consumption of alcohol.

Special Advise

  • Regular monitoring of blood pressure, kidney functioning, and amount of electrolytes such as sodium, potassium, magnesium, creatinine, and liver enzyme levels are recommended while taking ENACE D 5MG TABLET .
  • If you are about to take an anti-doping test, please inform your doctor that you are taking ENACE D 5MG TABLET as it may give a positive result.
  • Low salt diet and regular exercise are recommended along with ENACE D 5MG TABLET for effective results.

Disease/Condition Glossary

Hypertension: Blood pressure is the measurement of the heart's force to pump blood to all parts of the body. Hypertension is a chronic condition in which blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Normal blood pressure lies in between 90/60 mm of Hg and 120/80 mm of Hg. If the blood pressure is 140/90 mmHg or greater, it is considered high blood pressure. 

bannner image

Alcohol

Unsafe

Avoid alcohol consumption with ENACE D 5MG TABLET as it may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness or headache.

bannner image

Pregnancy

Unsafe

Please consult a doctor if you are pregnant. ENACE D 5MG TABLET is not recommended for pregnant women, especially in the second and third trimesters as it may cause birth defects or serious harm to the baby.

bannner image

Breast Feeding

Unsafe

ENACE D 5MG TABLET may be excreted in human milk. Therefore, ENACE D 5MG TABLET is not recommended for breastfeeding mothers as it may be unsafe for the baby. However, please consult a doctor.

bannner image

Driving

Caution

ENACE D 5MG TABLET may cause dizziness or tiredness in some people. Therefore, avoid driving if you feel dizzy or tired after taking ENACE D 5MG TABLET .

bannner image

Liver

Caution

ENACE D 5MG TABLET should be given with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking ENACE D 5MG TABLET if you have severe liver problems.

bannner image

Kidney

Caution

ENACE D 5MG TABLET should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking ENACE D 5MG TABLET if you have severe kidney problems.

bannner image

Children

Unsafe

It is not recommended for children as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

401, LSC, C-Block, Mohan Place Saraswati Vihar Delhi DL 110034 In
Other Info - ENA0040

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

ENACE D 5MG TABLET is used to treat hypertension (high blood pressure).
ENACE D 5MG TABLET contains Enalapril and Hydrochlorothiazide. Enalapril belongs to the class angiotensin-converting enzyme (ACE) inhibitors that work by blocking an angiotensin-converting enzyme which decreases the production of angiotensin II in the body that causes constriction and narrowing of blood vessels leading to high blood pressure. Thereby, it widens and relaxes blood vessels. Hydrochlorothiazide is a diuretic (water tablet) that increases the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels. Thus, together they lower high blood pressure.
You are not recommended to take furosemide with ENACE D 5MG TABLET as co-administration of these two medicines may increase the risk of low blood pressure. However, if you experience dizziness, reduced heart rate, headache or fainting, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted to use safely.
It is advised to inform your doctor if you have had skin cancer or develop an unexpected skin lesion as hydrochlorothiazide in ENACE D 5MG TABLET may increase the risk of certain types of skin and lip cancer especially when taken in high doses for a long period. Therefore, it is recommended to protect the skin from UV rays and sun exposure while taking ENACE D 5MG TABLET .
No, you are not recommended to take potassium supplements with ENACE D 5MG TABLET as it may increase the levels of potassium in the blood (hyperkalaemia). However, please consult a doctor before taking other medicines with ENACE D 5MG TABLET .
If you have any kidney problems, it is advised to inform your doctor before taking ENACE D 5MG TABLET as ENACE D 5MG TABLET may worsen kidney functioning if there is any existing kidney problem. However, if you experience unexplained weight gain, swelling in feet, ankles or hands, please consult your doctor immediately.
You are not recommended to take more than the prescribed dose of ENACE D 5MG TABLET as it may cause ENACE D 5MG TABLET overdose resulting in symptoms such as low blood pressure, cough, nausea, dizziness, cramps, drowsiness, fast or slow heartbeat, anxiety, increased urination or difficulty in urination. However, if you experience any of these symptoms while taking ENACE D 5MG TABLET , please consult a doctor immediately.ENACE D 5MG TABLET belongs to a class of medication called 'anti-hypertensive' primarily used to treat hypertension (high blood pressure). Hypertension is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.