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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Empov 125/80Mg Capsule is used to prevent nausea and vomiting caused by chemotherapy (anti-cancer medicines) in adults and adolescents aged 12 years and above. It contains Aprepitant, which blocks a chemical that produces vomiting by acting on the neurological system. Thus, it helps prevent nausea and vomiting.

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Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Empov 125/80Mg Capsule

Empov 125/80Mg Capsule belongs to a class of drugs called anti-emetics. It is used to prevent nausea and vomiting caused by chemotherapy (anti-cancer medicines) in adults and adolescents aged 12 years and above. Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

Empov 125/80Mg Capsule contains Aprepitant. Aprepitant blocks a chemical that produces vomiting by acting on the neurological system. Thus, it helps prevent nausea and vomiting.

Take Empov 125/80Mg Capsule as prescribed. You are recommended to take Empov 125/80Mg Capsule for as long as your doctor has advised it. In some cases, Empov 125/80Mg Capsule may cause common side effects such as headache, constipation, loss of appetite, tiredness, indigestion, and hiccups. Most of these side effects do not require medical attention and gradually resolve over time. However, inform your doctor if the side effects persist or worsen.

Please tell your doctor if you are allergic to Empov 125/80Mg Capsule or any other medicines. Empov 125/80Mg Capsule is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please inform your doctor before taking Empov 125/80Mg Capsule. Avoid driving or operating machinery if you feel dizzy or sleepy after taking Empov 125/80Mg Capsule. If you are taking other prescription or non-prescription medicines, inform your doctor before taking Empov 125/80Mg Capsule.

Uses of Empov 125/80Mg Capsule

Treatment of Chemotherapy-induced nausea and vomiting

Directions for Use

Take Empov 125/80Mg Capsule with or without food as advised by your doctor. Always take Empov 125/80Mg Capsule together with other medicines. Swallow it as a whole with some liquid; do not crush, break or chew it.

Medicinal Benefits

Empov 125/80Mg Capsule contains Aprepitant, an anti-emetic (a drug used to treat nausea and vomiting) that works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it helps to prevent nausea and vomiting caused by anti-cancer medicines in adults and adolescents from the age of 12 years.

How Empov 125/80Mg Capsule Works

Empov 125/80Mg Capsule contains Aprepitant, which blocks a chemical that produces vomiting by acting on the neurological system. Thus, it helps prevent nausea and vomiting.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Empov 125/80Mg Capsule

  • Headache
  • Constipation
  • Loss of appetite
  • Tiredness
  • Indigestion
  • Hiccups

What if I have taken an overdose of Empov 125/80Mg Capsule

Since Empov 125/80Mg Capsule is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

Please tell your doctor if you are allergic to Empov 125/80Mg Capsule or any other medicines. Empov 125/80Mg Capsule is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please inform your doctor before taking Empov 125/80Mg Capsule. Avoid driving or operating machinery if you feel dizzy or sleepy after taking Empov 125/80Mg Capsule. If you are taking any other prescription or non-prescription medicines, inform your doctor before taking Empov 125/80Mg Capsule.

Drug-Drug Interactions

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AprepitantLomitapide
Critical
AprepitantEliglustat
Critical

Drug-Drug Interactions

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AprepitantLomitapide
Critical
How does the drug interact with Empov 125/80Mg Capsule:
Lomitapide blood levels can be significantly increased by combining it with Empov 125/80Mg Capsule.

How to manage the interaction:
Although using Lomitapide and Empov 125/80Mg Capsule together may cause an interaction, they can be taken if advised by a doctor. Consult a doctor if you have any of the following symptoms: diarrhea, nausea, vomiting, stomach pain or discomfort, indigestion, gas, constipation, liver problems causing fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, dark colored urine, light-colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
AprepitantEliglustat
Critical
How does the drug interact with Empov 125/80Mg Capsule:
Empov 125/80Mg Capsule combined with Eliglustat can considerably raise blood levels of Eliglustat. This raises the possibility of cardiac adverse effects such as abnormal heart rhythm, heart block, and cardiac arrest.

How to manage the interaction:
Taking Empov 125/80Mg Capsule and Eliglustat together is not recommended as it can lead to an interaction; they can be consumed if prescribed by a doctor. Consult a doctor if you have symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, weak heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
AprepitantTerfenadine
Critical
How does the drug interact with Empov 125/80Mg Capsule:
Co-administration with Empov 125/80Mg Capsule and Terfenadine may increase the blood levels of Terfenadine and leads to irregular heartbeat.

How to manage the interaction:
Taking Empov 125/80Mg Capsule and Terfenadine together is not recommended as it can lead to an interaction. It is safe to do so if your doctor has prescribed it. Contact a doctor if you have palpitations, an irregular pulse, sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not stop taking any medications without visiting a doctor.
AprepitantCisapride
Critical
How does the drug interact with Empov 125/80Mg Capsule:
Co-administration with Empov 125/80Mg Capsule and Cisapride may cause irregular heart rhythm.

How to manage the interaction:
Although taking Empov 125/80Mg Capsule and Cisapride together is not recommended as it can lead to an interaction, it is safe to do so if your doctor has prescribed it. Contact a doctor if you have palpitations, an irregular pulse, sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not stop taking any medications without visiting a doctor.
AprepitantPimozide
Critical
How does the drug interact with Empov 125/80Mg Capsule:
Using pimozide together with Empov 125/80Mg Capsule may significantly increase the blood levels of pimozide. High blood levels of pimozide can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Empov 125/80Mg Capsule and Pimozide together is not recommended; as it can lead to an interaction, you can take them if your doctor advises you to. If you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or a rapid heartbeat, get immediate medical help. Do not discontinue any medications without consulting a doctor.
AprepitantFlibanserin
Critical
How does the drug interact with Empov 125/80Mg Capsule:
Using flibanserin together with Empov 125/80Mg Capsule can significantly increase the blood levels of flibanserin.

How to manage the interaction:
Taking Flibanserin and Empov 125/80Mg Capsule together is not recommended as it can lead to an interaction; they can be taken if prescribed by a doctor. Consult a doctor if you develop any symptoms, such as extreme sleepiness or low blood pressure, that cause dizziness, lightheadedness, or fainting. To reduce the chance of these side effects, use Flibanserin at bedtime. Do not discontinue any medications without consulting a doctor.
AprepitantAstemizole
Critical
How does the drug interact with Empov 125/80Mg Capsule:
Co-administration with Empov 125/80Mg Capsule and Astemizole may increase the blood levels of Astemizole.

How to manage the interaction:
Although taking Empov 125/80Mg Capsule and Astemizole together is not recommended as it can lead to an interaction, it is safe if your doctor has prescribed it. Contact a doctor if you have palpitations, an irregular pulse, sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not stop taking any medications without visiting a doctor. Astemizole should not be combined with any other medications without a doctor's advice.
AprepitantAcalabrutinib
Severe
How does the drug interact with Empov 125/80Mg Capsule:
Coadministration of Empov 125/80Mg Capsule can significantly increase the blood levels of Acalabrutinib.

How to manage the interaction:
Although there is an interaction between Empov 125/80Mg Capsule and acalabrutinib, it can be taken if prescribed by a doctor. A doctor should be consulted if you experience any of the following symptoms: paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscular aches, shortness of breath, blood in the phlegm, red or irritated skin, body sores, and discomfort when urinating. Without consulting a doctor, never stop taking medicines.
AprepitantColchicine
Severe
How does the drug interact with Empov 125/80Mg Capsule:
Co-administration of Empov 125/80Mg Capsule with colchicine may raise blood levels of colchicine, which can have an effect on the neurological system and other organs such as the liver and kidneys.

How to manage the interaction:
Although taking Empov 125/80Mg Capsule with colchicine may cause an interaction, it is safe to do so if advised by your doctor. Consult a doctor if you have abdominal discomfort, nausea, vomiting, diarrhea, fever, muscle pain, fatigue, weakness, or numbness or tingling in your hands or feet. Do not discontinue any medications without consulting a doctor.
AprepitantNaloxegol
Severe
How does the drug interact with Empov 125/80Mg Capsule:
Coadministration of Empov 125/80Mg Capsule with Naloxegol the blood levels of Naloxegol may significantly increase.

How to manage the interaction:
Although there is an interaction between Empov 125/80Mg Capsule and naloxegol, it can be taken if prescribed by a doctor. If you have a lot of sweating, tears, a runny nose, chills, diarrhea, abdominal pain, nervousness, sleeplessness, irritability, restlessness, or a lot of yawning, consult a doctor. Without consulting a doctor, never stop taking medicines.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy and low-fat diet that includes lots of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, and plant-based oils, especially in small portions, as it will be easy for digestion.
  • Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.
  • Increase the intake of fluids. Drink a small amount of water after small intervals to stay hydrated.
  • Avoid taking greasy or oily foods, as these foods trigger nausea and vomiting.
  • If the smell of food makes you feel sick (vomit), do not cook food, as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Empov 125/80Mg Capsule Substitute

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Alcohol

Caution

The interaction of alcohol with Empov 125/80Mg Capsule is unknown. If you have any concerns regarding this, please discuss them with your doctor.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, inform your doctor before taking Empov 125/80Mg Capsule. Your doctor may prescribe this medicine only if clearly needed.

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Breast Feeding

Consult your doctor

It is unknown whether Aprepitant is excreted in breast milk. Hence, if you are a nursing mother, inform your doctor before taking Empov 125/80Mg Capsule.

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Driving

Caution

Empov 125/80Mg Capsule may cause dizziness or drowsiness in some people. Hence, do not drive or operate machinery if you feel dizzy or drowsy after taking Empov 125/80Mg Capsule.

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Liver

Consult your doctor

If you have liver disease, inform your doctor before taking Empov 125/80Mg Capsule. Your doctor may monitor your liver condition.

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Kidney

Consult your doctor

If you have kidney problems, inform your doctor before taking Empov 125/80Mg Capsule.

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Children

Unsafe

Empov 125/80Mg Capsule is not recommended for children below 12 years of age.

FAQs

Empov 125/80Mg Capsule is used to treat Chemotherapy-induced nausea and vomiting.

Empov 125/80Mg Capsule contains Aprepitant, an anti-emetic (a drug used to treat nausea and vomiting) that works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it helps to prevent nausea and vomiting caused by anti-cancer medicines in adults and adolescents from the age of 12 years.

You are not recommended to take erythromycin with Empov 125/80Mg Capsule as it may increase the blood levels and effects of Empov 125/80Mg Capsule. Contact your doctor if your condition changes or you experience side effects such as diarrhoea, constipation, nausea, or loss of appetite. However, please consult your doctor before taking other medicines with Empov 125/80Mg Capsule.

You are advised not to take hormonal birth control medicines such as birth control pills, implants, skin patches, and certain Intrauterine devices (IUDs) as they may not work properly when taken together with Empov 125/80Mg Capsule. Therefore, you are recommended to use another or additional non-hormonal form of birth control method during treatment with Empov 125/80Mg Capsule and for up to 2 months after using Empov 125/80Mg Capsule.

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA
Other Info - EMP0006

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