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  3. Durataf 25 Tablet 30's

Durataf 25 Tablet 30's, Pack of 1 Tablet
Durataf 25 Tablet 30's, Pack of 1 Tablet
Durataf 25 Tablet 30's, Pack of 1 Tablet
Durataf 25 Tablet 30's, Pack of 1 Tablet
Durataf 25 Tablet 30's, Pack of 1 Tablet
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
DURATAF 25MG TABLET is used to treat chronic hepatitis B virus (HBV) infection. It contains Tenofovir alafenamide which works by inhibiting HBV replication and clears the infection. In some cases, this medicine may cause side effects like headaches, diarrhoea, nausea, vomiting, and rash. Keep the doctor informed about your health condition and the medications you are taking.
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Composition :

TENOFOVIR ALAFENAMIDE-25MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About DURATAF 25MG TABLET

DURATAF 25MG TABLET belongs to the group of medicines known as ‘antiviral medicines used to treat chronic hepatitis B virus (HBV) infection in adults with compensated liver disease. Chronic hepatitis B is a long-term viral infection caused by the hepatitis B virus.

DURATAF 25MG TABLET contains ‘Tenofovir alafenamide’. It inhibits HBV replication by incorporating the HBV reverse transcriptase into viral DNA, resulting in DNA chain termination. Thereby, it prevents the virus from producing new viruses and clears the infection.

Take DURATAF 25MG TABLET as prescribed by your doctor. Therapy should be initiated by a physician experienced in managing chronic hepatitis B. You may sometimes experience headaches, diarrhoea, vomiting, feeling sick (nausea), and rash. Most of these side effects of DURATAF 25MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

You should not take DURATAF 25MG TABLET if you are allergic to DURATAF 25MG TABLET or any other contents present in it. Avoid taking DURATAF 25MG TABLET if you have or had a history of severe kidney or liver impairment. Inform your doctor if you are pregnant, planning to become pregnant, and breastfeeding. Avoid drinking alcohol as it may increase the risk of side effects. You are recommended to avoid driving while using DURATAF 25MG TABLET as it may cause dizziness, affecting your ability to drive or use machines. Should not use DURATAF 25MG TABLET for children less than 12 years of age. Patients should take necessary precautions to avoid infecting others.

Uses of DURATAF 25MG TABLET

Treatment of Chronic hepatitis B

Directions for Use

DURATAF 25MG TABLET should be swallowed as a whole with water; do not crush, break or chew it.

Medicinal Benefits

DURATAF 25MG TABLET ‘tenofovir alafenamide’, an antiviral drug used to treat hepatitis B virus (HBV) infection in adults with compensated liver disease. It inhibits HBV replication by incorporating the HBV reverse transcriptase into viral DNA, resulting in DNA chain termination. Thereby it prevents the virus from producing new viruses and cleans up your infection.

How DURATAF 25MG TABLET Works

DURATAF 25MG TABLET contains ‘Tenofovir alafenamide’. It inhibits HBV replication by incorporating the HBV reverse transcriptase into viral DNA, resulting in DNA chain termination. Thereby, it prevents the virus from producing new viruses and clears the infection.

Storage

Store in a cool and dry place away from sunlight

Side Effects of DURATAF 25MG TABLET

  • Diarrhoea

  • Vomiting

  • Feeling sick (nausea)

  • Dizziness

  • Stomach pain

  • Joint pain

  • Feeling bloated

  • Wind (flatulence)

  • Feeling tired

What if I have taken an overdose of DURATAF 25MG TABLET

Take DURATAF 25MG TABLET only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

You should not take DURATAF 25MG TABLET if you are allergic to DURATAF 25MG TABLET or any other contents present in it. Avoid taking DURATAF 25MG TABLET if you have or had a history of severe kidney or liver impairment. Inform your doctor if you are pregnant, planning to become pregnant, and breastfeeding. Avoid drinking alcohol as it may increase the risk of side effects. You should not drive while using DURATAF 25MG TABLET as DURATAF 25MG TABLET may cause dizziness, affecting your ability to drive or use machines. DURATAF 25MG TABLET is not recommended for children less than 12 years of age. Patients should take necessary precautions to avoid infecting others.

Drug-Drug Interactions

verifiedApollotooltip
Tenofovir alafenamideCidofovir
Critical
Tenofovir alafenamideAmphotericin b
Severe

Drug-Drug Interactions

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Tenofovir alafenamideCidofovir
Critical
How does the drug interact with Durataf 25 Tablet:
Coadministration of Cidofovir and Durataf 25 Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Cidofovir and Durataf 25 Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Tenofovir alafenamideAmphotericin b
Severe
How does the drug interact with Durataf 25 Tablet:
Durataf 25 Tablet can cause kidney problems and taking it with amikacin, can enhance the risk.

How to manage the interaction:
There may be a possibility of interaction between Amphotericin b and Durataf 25 Tablet, but it can be taken if prescribed by a doctor. However, consult a doctor if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm. Do not discontinue any medications without a doctor's advice.
Tenofovir alafenamideCyclophosphamide
Severe
How does the drug interact with Durataf 25 Tablet:
Co-administration of Durataf 25 Tablet may cause kidney problems, and combining it with Cyclophosphamide may increase the risk.

How to manage the interaction:
Although there is a possible interaction, Cyclophosphamide can be taken with Durataf 25 Tablet if prescribed by the doctor. Consult the doctor if you develop signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop any medication without consulting a doctor.
Tenofovir alafenamidePolymyxin b
Severe
How does the drug interact with Durataf 25 Tablet:
Taking Durataf 25 Tablet with Polymyxin B can increase the chance of side effects.

How to manage the interaction:
Taking Durataf 25 Tablet with Polymyxin b together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Tenofovir alafenamideCiclosporin
Severe
How does the drug interact with Durataf 25 Tablet:
Co-administration of Durataf 25 Tablet with ciclosporin may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction, Durataf 25 Tablet can be taken with ciclosporin if prescribed by the doctor. However, consult the doctor if you experience side effects such as diarrhea, nausea, vomiting, abdominal pain, dizziness, weakness, headache, shaking, fits, fever, sore throat, unusual bruising or bleeding, and increased or decreased urination. Do not discontinue the medication without a doctor's advice.
Tenofovir alafenamideMeloxicam
Severe
How does the drug interact with Durataf 25 Tablet:
Co-administration of Meloxicam with Durataf 25 Tablet together can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Meloxicam with Durataf 25 Tablet together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms - feeling sick, gaining or losing weight suddenly, holding onto fluids, swelling, trouble breathing, bone or muscle pain, feeling weak or dizzy, feeling confused, or having an irregular heartbeat - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Tenofovir alafenamideCisplatin
Severe
How does the drug interact with Durataf 25 Tablet:
The combined use of Cisplatin and Durataf 25 Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Cisplatin and Durataf 25 Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Tenofovir alafenamideFlurbiprofen
Severe
How does the drug interact with Durataf 25 Tablet:
Co-administration of Durataf 25 Tablet with Flurbiprofen can increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Durataf 25 Tablet with Flurbiprofen can possibly result in an interaction, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not stop using any medications without consulting a doctor.
Tenofovir alafenamideIfosfamide
Severe
How does the drug interact with Durataf 25 Tablet:
The combined use of Ifosfamide and Durataf 25 Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Ifosfamide and Durataf 25 Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
Tenofovir alafenamideCarbamazepine
Severe
How does the drug interact with Durataf 25 Tablet:
Taking carbamazepine and Durataf 25 Tablet together may possibly reduce the blood levels of Durataf 25 Tablet.

How to manage the interaction:
Although there is a interaction between carbamazepine and Durataf 25 Tablet, but it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a diet that includes fresh fruits and vegetables.
  • Opt for lean meat such as skinless chicken and fish.
  • Limit processed and high-sugar foods.
  • Avoid acidic foods such as tomatoes, lemons, and oranges.
  • Limit alcohol intake and quit smoking.
  • Exercise regularly as it promotes both physical and mental health.
  • Take the necessary precautions to avoid the spread of infection to other people.

Habit Forming

No

Therapeutic Class

ANTIVIRALS

DURATAF 25MG TABLET Substitute

Substitutes safety advice

  • Tafnat 25 Tablet 30's

    by AYUR

    ₹42.91per tablet

  • TENVIR AF 25MG TABLET 30'S

    by AYUR

    ₹43.94per tablet

  • Hepbest Tablet 30's

    by Others

    ₹48.17per tablet

  • Tenohep-AF Tablet 30's

    by AYUR

    ₹49.26per tablet

  • Tentide AF 25 Tablet 30's

    by AYUR

    ₹49.26per tablet

Product Substitutes

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Alcohol

Unsafe

Avoid drinking alcohol. Consuming alcohol while using DURATAF 25MG TABLET may worsen the condition.

bannner image

Pregnancy

Caution

DURATAF 25MG TABLET is not recommended during pregnancy. However, your doctor may prescribe it for you during pregnancy if he/she feels that the benefit to you outweighs the risk. You should not take DURATAF 25MG TABLET without the doctor's advice.

bannner image

Breast Feeding

Caution

Consult your doctor, and there is no substantial research yet on the use of DURATAF 25MG TABLET in breastfeeding/nursing mothers.

bannner image

Driving

Caution

DURATAF 25MG TABLET can cause dizziness. If you feel dizzy when taking DURATAF 25MG TABLET , do not drive and use any tools or machines.

bannner image

Liver

Caution

Consult your doctor before taking DURATAF 25MG TABLET if you have a liver impairment or any concerns regarding this. Your doctor will weigh the benefits and any potential risks before prescribing them to you.

bannner image

Kidney

Caution

Consult your doctor before taking DURATAF 25MG TABLET if you have kidney impairment or any concerns regarding this. Your doctor will weigh the benefits and any potential risks before prescribing them to you.

bannner image

Children

Unsafe

Should not use DURATAF 25MG TABLET in children below 12 years of age.

FAQs

DURATAF 25MG TABLET belongs to the group of medicines known as ‘antiviral medicines used to treat chronic hepatitis B virus (HBV) infection.

DURATAF 25MG TABLET contains ‘tenofovir alfenamide’. It inhibits HBV replication by merging into viral DNA via HBV reverse transcriptase, resulting in the termination of the DNA chain. This prevents the virus from producing new viruses and cleans up your infection.

No, DURATAF 25MG TABLET is a prescribed medication given by a physician for treating HBV infection or Chronic hepatitis B. It is recommended not to take it on your own.

DURATAF 25MG TABLET should be taken in the dose and for the duration prescribed by your doctor based on your medical condition.

The main symptoms include yellowing of eyes and skin, flu-like symptoms, pale stools and dark-coloured urine.

A blood test (HBsAg blood test) can be used to determine if you have hepatitis B or have ever had it.

Practising safe sex and other lifestyle changes along with DURATAF 25MG TABLET might lower the risk of HIV transmission. However, it may not prevent the spread of hepatitis B virus (HBV) to other people.

DURATAF 25MG TABLET should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.

Yes, DURATAF 25MG TABLET is safe if taken in the dose and duration prescribed by the doctor.

DURATAF 25MG TABLET should be swallowed as a whole with water; do not crush or chew it.

Take another dose of DURATAF 25MG TABLET if you have vomited within an hour of taking the medicine. However, you may not need to take another dose if it has been more than an hour. Take the next dose at the scheduled time.

If you miss a dose of DURATAF 25MG TABLET take it as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.

DURATAF 25MG TABLET may cause side effects like headaches, diarrhoea, vomiting, feeling sick (nausea), and rash. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA
Other Info - DUR0251

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Author Details

Doctor imageDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Doctor imageDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jan 1, 2025 | 2:47 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/208464s008lbl.pdf
  2. https://www.ema.europa.eu/en/documents/product-information/vemlidy-epar-product-information_en.pdf
  3. https://www.medicines.org.uk/emc/medicine/32756#gref
  4. https://www.nhs.uk/conditions/hepatitis-b/
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