DURATAF 25MG TABLET belongs to the group of medicines known as ‘antiviral medicines used to treat chronic hepatitis B virus (HBV) infection in adults with compensated liver disease. Chronic hepatitis B is a long-term viral infection caused by the hepatitis B virus.

DURATAF 25MG TABLET contains ‘Tenofovir alafenamide’. It inhibits HBV replication by incorporating the HBV reverse transcriptase into viral DNA, resulting in DNA chain termination. Thereby, it prevents the virus from producing new viruses and clears the infection.

Take DURATAF 25MG TABLET as prescribed by your doctor. Therapy should be initiated by a physician experienced in managing chronic hepatitis B. You may sometimes experience headaches, diarrhoea, vomiting, feeling sick (nausea), and rash. Most of these side effects of DURATAF 25MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

You should not take DURATAF 25MG TABLET if you are allergic to DURATAF 25MG TABLET or any other contents present in it. Avoid taking DURATAF 25MG TABLET if you have or had a history of severe kidney or liver impairment. Inform your doctor if you are pregnant, planning to become pregnant, and breastfeeding. Avoid drinking alcohol as it may increase the risk of side effects. You are recommended to avoid driving while using DURATAF 25MG TABLET as it may cause dizziness, affecting your ability to drive or use machines. Should not use DURATAF 25MG TABLET for children less than 12 years of age. Patients should take necessary precautions to avoid infecting others.

DURATAF 25MG TABLET ‘tenofovir alafenamide’, an antiviral drug used to treat hepatitis B virus (HBV) infection in adults with compensated liver disease. It inhibits HBV replication by incorporating the HBV reverse transcriptase into viral DNA, resulting in DNA chain termination. Thereby it prevents the virus from producing new viruses and cleans up your infection.

• Diarrhoea

• Vomiting

• Feeling sick (nausea)

• Dizziness

• Stomach pain

• Joint pain

• Feeling bloated

• Wind (flatulence)

• Feeling tired

You should not take DURATAF 25MG TABLET if you are allergic to DURATAF 25MG TABLET or any other contents present in it. Avoid taking DURATAF 25MG TABLET if you have or had a history of severe kidney or liver impairment. Inform your doctor if you are pregnant, planning to become pregnant, and breastfeeding. Avoid drinking alcohol as it may increase the risk of side effects. You should not drive while using DURATAF 25MG TABLET as DURATAF 25MG TABLET may cause dizziness, affecting your ability to drive or use machines. DURATAF 25MG TABLET is not recommended for children less than 12 years of age. Patients should take necessary precautions to avoid infecting others.

Drug-Drug Interactions: DURATAF 25MG TABLET may interact with an antibiotic (e.g. tobramycin, pentamidine, vancomycin), antifungal medicines (e.g. amphotericin B), antiviral disease (e.g. foscarnet, ganciclovir), medications used to treat hepatitis B virus (e.g. adefovir), pain killer (e.g. ibuprofen). The relevance of a particular drug interaction varies from person to person.

Drug-Food Interactions: Avoid drinking alcohol. Consuming alcohol while using DURATAF 25MG TABLET may worsen the condition.

Drug-Disease Interactions: DURATAF 25MG TABLET should not be used in patients with bone disease or severe liver or kidney diseases.

• TOBRAMYCIN
• PENTAMIDINE
• VANCOMYCIN
• AMPHOTERICIN B
• FOSCARNET
• GANCICLOVIR
• ADEFOVIR
• IBUPROFEN

• Eat a diet that includes fresh fruits and vegetables.
• Opt for lean meat such as skinless chicken and fish.
• Limit processed and high-sugar foods.
• Avoid acidic foods such as tomatoes, lemons, and oranges.
• Limit alcohol intake and quit smoking.
• Exercise regularly as it promotes both physical and mental health.
• Take the necessary precautions to avoid the spread of infection to other people.

• If you take DURATAF 25MG TABLET , your doctor may regularly monitor liver function, kidney function, and bone density.

Hepatitis B: Hepatitis B is a potentially fatal liver infection caused by the hepatitis B virus (HBV). It is highly contagious (spreads from one person to another) and spreads by intimate contact with an infected individual, direct contact with infected blood, use of a contaminated needle, use of an infected razor/other personal objects, or transmission from mother to baby during birth. The virus can survive outside the body for up to 7 days. Chronic hepatitis B develops slowly, and symptoms may not be obvious until complications arise. Hepatitis B symptoms might occur three months after being exposed to the infection and can continue for two to twelve weeks. Chronic hepatitis B consequences include liver failure, liver cancer, and liver cirrhosis (scarring). Hepatitis B can be prevented by taking the vaccination.