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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Last Updated Oct 26, 2024 | 7:06 PM IST
Tenfoliv-AF Tablet is used to treat chronic hepatitis B virus (HBV) infection. It contains Tenofovir alafenamide which works by inhibiting HBV replication and clears the infection. In some cases, this medicine may cause side effects like headaches, diarrhoea, nausea, vomiting, and rash. Keep the doctor informed about your health condition and the medications you are taking.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Transcure Therapeutics Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Tenfoliv-AF Tablet

Tenfoliv-AF Tablet belongs to the group of medicines known as ‘antiviral medicines used to treat chronic hepatitis B virus (HBV) infection in adults with compensated liver disease. Chronic hepatitis B is a long-term viral infection caused by the hepatitis B virus.

Tenfoliv-AF Tablet contains ‘Tenofovir alafenamide’. It inhibits HBV replication by incorporating the HBV reverse transcriptase into viral DNA, resulting in DNA chain termination. Thereby, it prevents the virus from producing new viruses and clears the infection.

Take Tenfoliv-AF Tablet as prescribed by your doctor. Therapy should be initiated by a physician experienced in managing chronic hepatitis B. You may sometimes experience headaches, diarrhoea, vomiting, feeling sick (nausea), and rash. Most of these side effects of Tenfoliv-AF Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

You should not take Tenfoliv-AF Tablet if you are allergic to Tenfoliv-AF Tablet or any other contents present in it. Avoid taking Tenfoliv-AF Tablet if you have or had a history of severe kidney or liver impairment. Inform your doctor if you are pregnant, planning to become pregnant, and breastfeeding. Avoid drinking alcohol as it may increase the risk of side effects. You are recommended to avoid driving while using Tenfoliv-AF Tablet as it may cause dizziness, affecting your ability to drive or use machines. Should not use Tenfoliv-AF Tablet for children less than 12 years of age. Patients should take necessary precautions to avoid infecting others.

Uses of Tenfoliv-AF Tablet

Treatment of Chronic hepatitis B

Medicinal Benefits

Tenfoliv-AF Tablet ‘tenofovir alafenamide’, an antiviral drug used to treat hepatitis B virus (HBV) infection in adults with compensated liver disease. It inhibits HBV replication by incorporating the HBV reverse transcriptase into viral DNA, resulting in DNA chain termination. Thereby it prevents the virus from producing new viruses and cleans up your infection.

Directions for Use

Tenfoliv-AF Tablet should be swallowed as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tenfoliv-AF Tablet

  • Diarrhoea

  • Vomiting

  • Feeling sick (nausea)

  • Dizziness

  • Stomach pain

  • Joint pain

  • Feeling bloated

  • Wind (flatulence)

  • Feeling tired

Drug Warnings

You should not take Tenfoliv-AF Tablet if you are allergic to Tenfoliv-AF Tablet or any other contents present in it. Avoid taking Tenfoliv-AF Tablet if you have or had a history of severe kidney or liver impairment. Inform your doctor if you are pregnant, planning to become pregnant, and breastfeeding. Avoid drinking alcohol as it may increase the risk of side effects. You should not drive while using Tenfoliv-AF Tablet as Tenfoliv-AF Tablet may cause dizziness, affecting your ability to drive or use machines. Tenfoliv-AF Tablet is not recommended for children less than 12 years of age. Patients should take necessary precautions to avoid infecting others.

Drug Interactions

Drug-Drug Interactions: Tenfoliv-AF Tablet may interact with an antibiotic (e.g. tobramycin, pentamidine, vancomycin), antifungal medicines (e.g. amphotericin B), antiviral disease (e.g. foscarnet, ganciclovir), medications used to treat hepatitis B virus (e.g. adefovir), pain killer (e.g. ibuprofen). The relevance of a particular drug interaction varies from person to person.

Drug-Food Interactions: Avoid drinking alcohol. Consuming alcohol while using Tenfoliv-AF Tablet may worsen the condition.

Drug-Disease Interactions: Tenfoliv-AF Tablet should not be used in patients with bone disease or severe liver or kidney diseases.

Drug-Drug Interactions Checker List

  • TOBRAMYCIN
  • PENTAMIDINE
  • VANCOMYCIN
  • AMPHOTERICIN B
  • FOSCARNET
  • GANCICLOVIR
  • ADEFOVIR
  • IBUPROFEN

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a diet that includes fresh fruits and vegetables.
  • Opt for lean meat such as skinless chicken and fish.
  • Limit processed and high-sugar foods.
  • Avoid acidic foods such as tomatoes, lemons, and oranges.
  • Limit alcohol intake and quit smoking.
  • Exercise regularly as it promotes both physical and mental health.
  • Take the necessary precautions to avoid the spread of infection to other people.

Special Advise

  • If you take Tenfoliv-AF Tablet, your doctor may regularly monitor liver function, kidney function, and bone density.

Disease/Condition Glossary

Hepatitis B: Hepatitis B is a potentially fatal liver infection caused by the hepatitis B virus (HBV). It is highly contagious (spreads from one person to another) and spreads by intimate contact with an infected individual, direct contact with infected blood, use of a contaminated needle, use of an infected razor/other personal objects, or transmission from mother to baby during birth. The virus can survive outside the body for up to 7 days. Chronic hepatitis B develops slowly, and symptoms may not be obvious until complications arise. Hepatitis B symptoms might occur three months after being exposed to the infection and can continue for two to twelve weeks. Chronic hepatitis B consequences include liver failure, liver cancer, and liver cirrhosis (scarring). Hepatitis B can be prevented by taking the vaccination.

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Alcohol

Unsafe

Avoid drinking alcohol. Consuming alcohol while using Tenfoliv-AF Tablet may worsen the condition.

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Pregnancy

Caution

Tenfoliv-AF Tablet is not recommended during pregnancy. However, your doctor may prescribe it for you during pregnancy if he/she feels that the benefit to you outweighs the risk. You should not take Tenfoliv-AF Tablet without the doctor's advice.

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Breast Feeding

Caution

Consult your doctor, and there is no substantial research yet on the use of Tenfoliv-AF Tablet in breastfeeding/nursing mothers.

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Driving

Caution

Tenfoliv-AF Tablet can cause dizziness. If you feel dizzy when taking Tenfoliv-AF Tablet, do not drive and use any tools or machines.

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Liver

Caution

Consult your doctor before taking Tenfoliv-AF Tablet if you have a liver impairment or any concerns regarding this. Your doctor will weigh the benefits and any potential risks before prescribing them to you.

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Kidney

Caution

Consult your doctor before taking Tenfoliv-AF Tablet if you have kidney impairment or any concerns regarding this. Your doctor will weigh the benefits and any potential risks before prescribing them to you.

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Children

Unsafe

Should not use Tenfoliv-AF Tablet in children below 12 years of age.

Country of origin

India

Manufacturer/Marketer address

516, Ring Road Mall, Sector -3, Rohini, New Delhi – 110085
Other Info - TE16290

Author Details

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FAQs

Tenfoliv-AF Tablet belongs to the group of medicines known as ‘antiviral medicines used to treat chronic hepatitis B virus (HBV) infection.
Tenfoliv-AF Tablet contains ‘tenofovir alfenamide’. It inhibits HBV replication by merging into viral DNA via HBV reverse transcriptase, resulting in the termination of the DNA chain. This prevents the virus from producing new viruses and cleans up your infection.
No, Tenfoliv-AF Tablet is a prescribed medication given by a physician for treating HBV infection or Chronic hepatitis B. It is recommended not to take it on your own.
Tenfoliv-AF Tablet should be taken in the dose and for the duration prescribed by your doctor based on your medical condition.
The main symptoms include yellowing of eyes and skin, flu-like symptoms, pale stools and dark-coloured urine.
A blood test (HBsAg blood test) can be used to determine if you have hepatitis B or have ever had it.
Practising safe sex and other lifestyle changes along with Tenfoliv-AF Tablet might lower the risk of HIV transmission. However, it may not prevent the spread of hepatitis B virus (HBV) to other people.
Tenfoliv-AF Tablet should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.
Yes, Tenfoliv-AF Tablet is safe if taken in the dose and duration prescribed by the doctor.
Tenfoliv-AF Tablet should be swallowed as a whole with water; do not crush or chew it.
Take another dose of Tenfoliv-AF Tablet if you have vomited within an hour of taking the medicine. However, you may not need to take another dose if it has been more than an hour. Take the next dose at the scheduled time.
If you miss a dose of Tenfoliv-AF Tablet take it as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.
Tenfoliv-AF Tablet may cause side effects like headaches, diarrhoea, vomiting, feeling sick (nausea), and rash. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

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