Durapain Tablet belongs to the group of medicines called painkillers, primarily used to get relief from pain and inflammation (redness and swelling). Pain is an unpleasant sensation and emotional experience that is associated with tissue damage. It allows the body to react and prevent further tissue damage. Pain can be short-term (acute) or long-term (chronic). Perception of pain can differ from person to person where from tolerable to non-tolerable.

Durapain Tablet contains Diclofenac (non-steroidal anti-inflammatory drug (NSAID) and Tramadol (an opioid). Diclofenac works by blocking the release of chemical messengers, which are responsible for causing pain and inflammation. On the other hand, Tramadol blocks the transmission of pain signals to the brain, and as a result, pain perception is lowered.

Take Durapain Tablet as prescribed by your doctor. You are advised to take Durapain Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. The most common side effects of Durapain Tablet are nausea, loss of appetite, vomiting, dizziness, indigestion, sleepiness, constipation, heartburn, stomach pain, and dryness in the mouth. Most of these side effects of Durapain Tablet are temporary, do not require medical attention, and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not take Durapain Tablet if you are allergic to NSAIDs, diclofenac, tramadol, or any of the ingredients of Durapain Tablet . Consumption of alcohol should be avoided during the treatment with Durapain Tablet as it may lead to an increased risk of liver damage and stomach bleeding. Patients with stomach ulcers, gastric bleeding, severe heart failure, high blood pressure, and liver or kidney disease should not take Durapain Tablet . Durapain Tablet contains diclofenac, a category D pregnancy drug, so it is not recommended that you take Durapain Tablet during pregnancy as it may cause fetal deformities.

Durapain Tablet is used to treat aches and pains, along with problems of musculoskeletal and joint pain. It is helpful in the conditions of rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. In addition to this, it is also used as a short-term treatment for muscle and back pain, pain in the throat or ear, and toothache. Durapain Tablet contains Diclofenac (non-steroidal anti-inflammatory drug (NSAID)) and Tramadol (an opioid). Diclofenac works by blocking the release of chemical messengers, which are responsible for causing pain and inflammation. Tramadol, on the other hand, blocks the transmission of pain signals to the brain. As a result, pain perception is lowered, and hence the quality of life is improved. 

• Nausea 
• Vomiting
• Dryness in mouth
• Indigestion
• Constipation
• Sleepiness
• Heartburn
• Stomach pain
• Dizziness
• Loss of appetite

Do not take Durapain Tablet if you are allergic to NSAIDs, diclofenac, tramadol, or any of the ingredients of Durapain Tablet . Consumption of alcohol should be avoided during the treatment with Durapain Tablet as it may lead to increased risk of liver damage. Patients with stomach ulcers, gastric bleeding, severe heart failure, high blood pressure, and liver or kidney disease should not take Durapain Tablet . Durapain Tablet contains diclofenac, a category D pregnancy drug, so it is not recommended that you take Durapain Tablet during pregnancy as it may cause fetal deformities. While Durapain Tablet may pass in the lactating mother's breast milk, there is not enough evidence to establish the safety of Durapain Tablet in nursing mothers. So, it is advisable to take it only if prescribed by your doctor. If you have a severe allergy to painkillers and have conditions like asthma, rhinitis, angioedema (swelling under the skin), or skin rashes, immediately stop taking Durapain Tablet .

Drug-Drug Interactions: Durapain Tablet is known to interact with painkillers (nimesulide, oxyphenbutazone), blood clotting agents (warfarin), blood pressure-lowering agents (hydrochlorothiazide), medicines for depression (lithium), antifungals (itraconazole, voriconazole),  benzodiazepines (alprazolam, diazepam, estazolam, flurazepam, lorazepam, triazolam),  antibiotics (erythromycin), HIV medications (indinavir, nelfinavir, ritonavir) and medicines used to treat abnormal heart rhythms (quinidine).

Drug-Food Interactions: Durapain Tablet should not be taken along with St. John's Wort plant (a natural remedy to treat depression).

Drug-Disease Interactions: People with peptic ulcers, gastric bleeding, severe heart failure, diarrhoea and high blood pressure should avoid intake of Durapain Tablet as it may lead to life-threatening conditions.

• NIMESULIDE
• OXYPHENBUTAZONE
• WARFARIN
• HYDROCHLOROTHIAZIDE
• LITHIUM
• ITRACONAZOLE
• VORICONAZOLE
• ALPRAZOLAM
• DIAZEPAM
• ESTAZOLAM
• FLURAZEPAM
• LORAZEPAM
• TRIAZOLAM
• ERYTHROMYCIN
• INDINAVIR
• NELFINAVIR
• RITONAVIR
• QUINIDINE

• Include more glucosamine, chondroitin sulphate, vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.
• Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscle strength by lifting light weights.
• In a chronic condition of arthritis or joint pain, including fish like salmon, trout, tuna and sardines. These fishes are enriched with omega-3 fatty acids that minimize cytokine's levels, which ramp up inflammation.
• Your sitting posture is important, especially when you have pain and inflammation conditions. Try to sit as little as possible and only for a short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

• Durapain Tablet tends to cause stomach upset. Thus, it is recommended to consume Durapain Tablet with meals to minimize gastric side effects. If you have a peptic ulcer diagnosis, Durapain Tablet is best avoided unless prescribed by your doctor.
• Durapain Tablet can cause liver injury when taken in large doses. Concomitant use of alcohol is best avoided as it aggravates liver toxicity.
• Although it is generally a safe medicine to use, it should be avoided in patients with kidney disease as Durapain Tablet may harm renal functions.
• Durapain Tablet contains Tramadol, which is a habit-forming drug. So, it should be taken for a short duration to avoid unpleasant withdrawal symptoms like breathing difficulties.
• Although Durapain Tablet provides symptomatic relief in conditions like arthritis and may reduce the inflammation caused by these conditions, to achieve the best results, it is strongly recommended to remain physically active as much as your condition allows. Adopting a healthy lifestyle coupled with a healthy diet containing high proteins is the mainstay of managing arthritic conditions.

Pain: It is an unpleasant sensation and emotional experience that is associated with tissue damage. It allows the body to react and prevent further tissue damage. Pain can be short-term (acute) or long-term (chronic). Perception of pain can differ from person to person where from tolerable to non-tolerable.

Rheumatoid arthritis: It is an autoimmune disease that can cause joint pain and damage throughout your body. In this long-term condition, our body's immune system attacks its own tissue (including joints).

Ankylosing spondylitis (AS): It is a rare type of arthritis that affects the spine and larger joints, causing extreme pain and stiffness.

Osteoarthritis: It is a degenerative disease that worsens over time, often resulting in chronic pain. Joint pain and stiffness can become severe enough to make daily tasks difficult.