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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Duo Stop 50/75 Tablet is used to get relief from pain and inflammation (redness and swelling). It contains Diclofenac and Tramadol, which works by blocking the release of chemical messengers responsible for causing pain and inflammation. Also, it blocks the transmission of pain signals to the brain. It may cause common side effects such as nausea, loss of appetite, vomiting, dizziness, indigestion, sleepiness, constipation, heartburn, stomach pain, and dryness in the mouth. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Integrace Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Duo Stop 50/75 Tablet

Duo Stop 50/75 Tablet belongs to the group of medicines called painkillers, primarily used to get relief from pain and inflammation (redness and swelling). Pain is an unpleasant sensation and emotional experience that is associated with tissue damage. It allows the body to react and prevent further tissue damage. Pain can be short-term (acute) or long-term (chronic). Perception of pain can differ from person to person where from tolerable to non-tolerable.

Duo Stop 50/75 Tablet contains Diclofenac (non-steroidal anti-inflammatory drug (NSAID) and Tramadol (an opioid). Diclofenac works by blocking the release of chemical messengers, which are responsible for causing pain and inflammation. On the other hand, Tramadol blocks the transmission of pain signals to the brain, and as a result, pain perception is lowered.

Take Duo Stop 50/75 Tablet as prescribed by your doctor. You are advised to take Duo Stop 50/75 Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. The most common side effects of Duo Stop 50/75 Tablet are nausea, loss of appetite, vomiting, dizziness, indigestion, sleepiness, constipation, heartburn, stomach pain, and dryness in the mouth. Most of these side effects of Duo Stop 50/75 Tablet are temporary, do not require medical attention, and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not take Duo Stop 50/75 Tablet if you are allergic to NSAIDs, diclofenac, tramadol, or any of the ingredients of Duo Stop 50/75 Tablet . Consumption of alcohol should be avoided during the treatment with Duo Stop 50/75 Tablet as it may lead to an increased risk of liver damage and stomach bleeding. Patients with stomach ulcers, gastric bleeding, severe heart failure, high blood pressure, and liver or kidney disease should not take Duo Stop 50/75 Tablet . Duo Stop 50/75 Tablet contains diclofenac, a category D pregnancy drug, so it is not recommended that you take Duo Stop 50/75 Tablet during pregnancy as it may cause fetal deformities.

Uses of Duo Stop 50/75 Tablet

Treatment of Pain relief

Directions for Use

Take Duo Stop 50/75 Tablet with food or as advised by the doctor. Swallow it as a whole with a glass of water. Do not chew, or break it.

Medicinal Benefits

Duo Stop 50/75 Tablet is used to treat aches and pains, along with problems of musculoskeletal and joint pain. It is helpful in the conditions of rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. In addition to this, it is also used as a short-term treatment for muscle and back pain, pain in the throat or ear, and toothache. Duo Stop 50/75 Tablet contains Diclofenac (non-steroidal anti-inflammatory drug (NSAID)) and Tramadol (an opioid). Diclofenac works by blocking the release of chemical messengers, which are responsible for causing pain and inflammation. Tramadol, on the other hand, blocks the transmission of pain signals to the brain. As a result, pain perception is lowered, and hence the quality of life is improved. 

How Duo Stop 50/75 Tablet Works

Duo Stop 50/75 Tablet contains Diclofenac (non-steroidal anti-inflammatory drug (NSAID) and Tramadol (an opioid). Diclofenac works by blocking the release of chemical messengers, which are responsible for causing pain and inflammation. On the other hand, Tramadol blocks the transmission of pain signals to the brain, and as a result, pain perception is lowered.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Duo Stop 50/75 Tablet

  • Nausea 
  • Vomiting
  • Dryness in mouth
  • Indigestion
  • Constipation
  • Sleepiness
  • Heartburn
  • Stomach pain
  • Dizziness
  • Loss of appetite

What if I have taken an overdose of Duo Stop 50/75 Tablet

Do not take more than the prescribed dose of Duo Stop 50/75 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Duo Stop 50/75 Tablet if you are allergic to NSAIDs, diclofenac, tramadol, or any of the ingredients of Duo Stop 50/75 Tablet . Consumption of alcohol should be avoided during the treatment with Duo Stop 50/75 Tablet as it may lead to increased risk of liver damage. Patients with stomach ulcers, gastric bleeding, severe heart failure, high blood pressure, and liver or kidney disease should not take Duo Stop 50/75 Tablet . Duo Stop 50/75 Tablet contains diclofenac, a category D pregnancy drug, so it is not recommended that you take Duo Stop 50/75 Tablet during pregnancy as it may cause fetal deformities. While Duo Stop 50/75 Tablet may pass in the lactating mother's breast milk, there is not enough evidence to establish the safety of Duo Stop 50/75 Tablet in nursing mothers. So, it is advisable to take it only if prescribed by your doctor. If you have a severe allergy to painkillers and have conditions like asthma, rhinitis, angioedema (swelling under the skin), or skin rashes, immediately stop taking Duo Stop 50/75 Tablet .

Drug-Drug Interactions

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TramadolZiprasidone
Critical
TramadolAlvimopan
Critical

Drug-Drug Interactions

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TramadolZiprasidone
Critical
How does the drug interact with Duo Stop 50/75 Tablet 10's:
Co-administration of Ziprasidone with Duo Stop 50/75 Tablet 10's can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Duo Stop 50/75 Tablet 10's with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
TramadolAlvimopan
Critical
How does the drug interact with Duo Stop 50/75 Tablet 10's:
Co-administration of Duo Stop 50/75 Tablet 10's with Alvimopan can make the side effects worse or more dangerous.

How to manage the interaction:
Taking Alvimopan with Duo Stop 50/75 Tablet 10's is not recommended, please consult your doctor before taking it.
TramadolRasagiline
Critical
How does the drug interact with Duo Stop 50/75 Tablet 10's:
Taking rasagiline with Duo Stop 50/75 Tablet 10's can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Duo Stop 50/75 Tablet 10's with Rasagiline is not recommended, as it can lead to an interaction, but can be taken if advised by your doctor. However, if you experience any symptoms like severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
TramadolPhenelzine
Critical
How does the drug interact with Duo Stop 50/75 Tablet 10's:
Combining Phenelzine with Duo Stop 50/75 Tablet 10's can increase the risk of serotonin syndrome and seizures.

How to manage the interaction:
Taking Duo Stop 50/75 Tablet 10's with Phenelzine is not recommended, please consult your doctor before taking it.
TramadolLinezolid
Critical
How does the drug interact with Duo Stop 50/75 Tablet 10's:
Co-administration of Linezolid with Duo Stop 50/75 Tablet 10's can increase the risk of serotonin syndrome and seizures.

How to manage the interaction:
Taking Linezolid with Duo Stop 50/75 Tablet 10's is not recommended, consult a doctor before taking it. Consult a doctor if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not stop using any medications without talking to a doctor.
TramadolSafinamide
Critical
How does the drug interact with Duo Stop 50/75 Tablet 10's:
Taking Safinamide with Duo Stop 50/75 Tablet 10's can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Safinamide with Duo Stop 50/75 Tablet 10's is not recommended as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
TramadolTranylcypromine
Critical
How does the drug interact with Duo Stop 50/75 Tablet 10's:
Combining Tranylcypromine with Duo Stop 50/75 Tablet 10's can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Tranylcypromine with Duo Stop 50/75 Tablet 10's is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
DiclofenacMeloxicam
Critical
How does the drug interact with Duo Stop 50/75 Tablet 10's:
Co-administration of Duo Stop 50/75 Tablet 10's with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Duo Stop 50/75 Tablet 10's is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
TramadolTrazodone
Severe
How does the drug interact with Duo Stop 50/75 Tablet 10's:
Co-administration of Duo Stop 50/75 Tablet 10's with trazodone increases the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking trazodone with Duo Stop 50/75 Tablet 10's together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as confusion, hallucination, seizure, increased heart rate, blurred vision, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TramadolPromethazine
Severe
How does the drug interact with Duo Stop 50/75 Tablet 10's:
Co-administration of Duo Stop 50/75 Tablet 10's with promethazine can increase the risk of seizures (fits).

How to manage the interaction:
Taking promethazine with Duo Stop 50/75 Tablet 10's together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulphate, vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.
  • Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscle strength by lifting light weights.
  • In a chronic condition of arthritis or joint pain, including fish like salmon, trout, tuna and sardines. These fishes are enriched with omega-3 fatty acids that minimize cytokine's levels, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammation conditions. Try to sit as little as possible and only for a short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

Habit Forming

Yes

Therapeutic Class

ANALGESICS

Duo Stop 50/75 Tablet Substitute

Substitutes safety advice
  • Tralofen Tablet 10's

    9.90per tablet
  • Dolinsta Tablet

    by AYUR

    9.57per tablet
  • Tramasil-D Tablet 10's

    11.70per tablet
  • DIBOL TABLET

    6.78per tablet
  • Durapain Tablet 10's

    25.02per tablet
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Duo Stop 50/75 Tablet to avoid unpleasant side-effects like gastric bleeding.

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Pregnancy

Unsafe

Duo Stop 50/75 Tablet is not recommended for use in pregnant women.

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Breast Feeding

Unsafe

While Duo Stop 50/75 Tablet may pass in the lactating mother's breast milk, there is not enough evidence to establish the safety of Duo Stop 50/75 Tablet in nursing mothers. So, do it is advisable to take it only if prescribed by your doctor.

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Driving

Caution

In some cases, Duo Stop 50/75 Tablet may cause dizziness and drowsiness. So if you observe such symptoms, immediately stop the intake of Duo Stop 50/75 Tablet .

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Liver

Caution

Duo Stop 50/75 Tablet should be used with caution in patients with liver diseases. Therefore, the doctor may adjust the dose while using it in patients with liver diseases.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Duo Stop 50/75 Tablet .

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Children

Caution

Duo Stop 50/75 Tablet should not be given to children below the age of 18 as it is known to cause breathing problems (like slow breathing or difficulty in breathing)

FAQs

Duo Stop 50/75 Tablet is used to provide relief from pain and inflammation (redness and swelling).
Duo Stop 50/75 Tablet contains Diclofenac (non-steroidal anti-inflammatory drug (NSAID)) and Tramadol (an opioid). Diclofenac works by blocking the release of chemical messengers which are responsible to cause pain and inflammation. Tramadol, on the other hand, blocks the transmission of pain signals to the brain, and as a result pain perception is lowered.
Yes, Duo Stop 50/75 Tablet contains tramadol, which is known to decrease fertility in both men and women. Before starting Duo Stop 50/75 Tablet , inform your doctor if you plan to become pregnant as the salt might be changed.
Duo Stop 50/75 Tablet should be avoided in patients with known allergy to NSAIDs, diclofenac, tramadol or any of the ingredients of Duo Stop 50/75 Tablet . Duo Stop 50/75 Tablet if taken along with sleep medicines or MAO inhibitors (medicines to treat depression or Parkinson’s disease) can cause serious unpleasant side effects. Also, in patients suffering from liver disease or epilepsy, Duo Stop 50/75 Tablet should not be used.
Yes, prolonged use of Duo Stop 50/75 Tablet can cause kidney damage as pain killers reduce prostaglandin levels (a chemical), which protects the kidneys from damage and helps in its normal functioning. So, Duo Stop 50/75 Tablet is mostly prescribed as a short term medication to avoid any kidney damage.
Duo Stop 50/75 Tablet may impair mental and/or physical abilities required for the performance of heavy tasks like operating machinery or driving a motor vehicle, especially when used with alcohol or other CNS depressants (sleeping pills or anti-anxiety pills).
Do not take Duo Stop 50/75 Tablet for longer durations as it might increase the risk of heart problems, liver problems, breathing problems, and stomach bleeding/ulcer. Please consult a doctor before its use.
Yes, Duo Stop 50/75 Tablet contains tramadol, which an opioid and is habit-forming. So, it is recommended not to take Duo Stop 50/75 Tablet for prolonged use as it may lead to unpleasant withdrawal symptoms like breathing problems, heart problems, liver/kidney problems.
Yes,the use of Duo Stop 50/75 Tablet can cause constipation. Consult a doctor if constipation persists.
You should not stop taking Duo Stop 50/75 Tablet abruptly without consulting your doctor, as sudden discontinuation can lead to withdrawal symptoms like breathing problems, heart problems, liver/kidney problems or a return of pain. Consult the doctor before stopping Duo Stop 50/75 Tablet as they may suggest gradually reducing the dose to prevent complications. Always follow the doctor's instructions when discontinuing any medication.
Yes, Duo Stop 50/75 Tablet may cause mouth dryness as a common side effect. To overcome this, chew sugar-free gum, drink plenty of water throughout the day, or suck on sugar-free lozenges to stimulate saliva production. Using a humidifier at night and avoiding alcohol, tobacco, and caffeine can also help alleviate mouth dryness. If this symptom persists, consult the doctor for further advice.
Duo Stop 50/75 Tablet should be stored in a cool and dry place away from sunlight. Keep it out of sight and reach of children.
The side effects of Duo Stop 50/75 Tablet include loss of appetite, nausea, vomiting, dizziness, indigestion, sleepiness, constipation, heartburn, stomach pain, and dryness in the mouth. Consult the doctor if any of these side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai €“ 400 026.
Other Info - DUO0227

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