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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Duraflex Tablet is used to reduce and relieve pain due to muscle spasms (excessive tension in the muscles). It contains Diclofenac and Metaxalone, which works by blocking the effect of chemical messengers that cause pain and inflammation. Also, it blocks the nerve impulses and pain sensations in the brain, thereby helping to maintain muscle strength and relieving muscle spasms or stiffness. In some cases, it may cause common side effects such as stomach pain, nausea, vomiting, diarrhoea, dizziness and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Zoic Life Sciences

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Duraflex Tablet

Duraflex Tablet is used to reduce and relieve pain due to muscle spasms (excessive tension in the muscles). Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms.

Duraflex Tablet contains Diclofenac and Metaxalone. Diclofenac works by blocking the effect of chemical messengers that cause pain and inflammation. Metaxalone works by blocking the nerve impulses and pain sensations in the brain, thereby helping to maintain muscle strength and relieving muscle spasms or stiffness. Together, Duraflex Tablet helps in relieving pain due to muscle spasms.

You are advised to take Duraflex Tablet as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Duraflex Tablet may cause common side effects such as stomach pain, nausea, vomiting, diarrhoea, dizziness and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Duraflex Tablet may cause drowsiness and dizziness, so drive only if you are alert. Duraflex Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Duraflex Tablet as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Duraflex Tablet

Treatment of Pain due to muscle spasm.

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Duraflex Tablet is a combination of two drugs: Diclofenac and Metaxalone. Diclofenac is an NSAID (Non-Steroidal Anti-Inflammatory Drug), and metaxalone is a skeletal muscle relaxant. Duraflex Tablet is used to reduce and relieve pain due to muscle spasms (excessive tension in the muscles). Diclofenac works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Metaxalone works on the centres of the spinal cord and brain, thereby helping to maintain muscle strength and relieving muscle spasms or stiffness. Together, Duraflex Tablet helps in relieving pain due to muscle spasms.

How Duraflex Tablet Works

Duraflex Tablet contains Diclofenac and Metaxalone. Diclofenac works by blocking the effect of chemical messengers that cause pain and inflammation. Metaxalone works by blocking the nerve impulses and pain sensations in the brain, thereby helping to maintain muscle strength and relieving muscle spasms or stiffness. Together, Duraflex Tablet helps in relieving pain due to muscle spasms.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Duraflex Tablet

  • Stomach pain
  • Nausea
  • Vomiting
  • Diarrhoea
  • Dizziness
  • Headache

What if I have taken an overdose of Duraflex Tablet

Do not take more than the prescribed dose of Duraflex Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

If you have had any recent heart surgery, do not take Duraflex Tablet unless advised by the doctor as it may increase the risk of fatal heart attack or stroke. Do not take Duraflex Tablet if you are allergic to any of its components, have severe heart failure, or have suffered bleeding problems such as bleeding from the stomach or bowels while taking any painkillers. Inform your doctor before taking Duraflex Tablet if you have/had high blood pressure, heart problems, high cholesterol, diabetes, asthma, liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. Duraflex Tablet may cause drowsiness and dizziness, so drive only if you are alert. Duraflex Tablet should not be given to children as safety has not been established. Avoid consuming alcohol along with Duraflex Tablet as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Stop taking Duraflex Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach such as blood in stools. Do not take any other NSAIDs for pain relief along with Duraflex Tablet unless prescribed. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
DiclofenacDalteparin
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Duraflex Tablet 10's:
Co-administration of Duraflex Tablet 10's with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Duraflex Tablet 10's is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacDalteparin
Severe
How does the drug interact with Duraflex Tablet 10's:
Co-administration use of Duraflex Tablet 10's with Dalteparin may increase the risk of bleeding complications.

How to manage the interaction:
Although taking Dalteparin with Duraflex Tablet 10's may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
DiclofenacFondaparinux
Severe
How does the drug interact with Duraflex Tablet 10's:
Coadministration of Duraflex Tablet 10's with fondaparinux may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Duraflex Tablet 10's and Fondaparinux when taken together, but they can be taken together if your doctor has prescribed them. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DiclofenacOxaprozin
Severe
How does the drug interact with Duraflex Tablet 10's:
Taking Duraflex Tablet 10's and oxaprozin can increase the risk of side effects.

How to manage the interaction:
Co-administration of Duraflex Tablet 10's and oxaprozin can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacLeflunomide
Severe
How does the drug interact with Duraflex Tablet 10's:
Co administration of Duraflex Tablet 10's with Leflunomide may result in liver problems.

How to manage the interaction:
Co-administration of Duraflex Tablet 10's and Leflunomide can lead to an interaction; it can be taken if advised by your doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, or yellowing of the skin or eyes. Do not stop using any medication without consulting your doctor.
DiclofenacTenofovir alafenamide
Severe
How does the drug interact with Duraflex Tablet 10's:
Co-administration of Duraflex Tablet 10's and tenofovir alafenamide may cause kidney problems.

How to manage the interaction:
There may be a possible interaction between Duraflex Tablet 10's and Tenofovir alafenamide but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.
DiclofenacAmiloride
Severe
How does the drug interact with Duraflex Tablet 10's:
Taking amiloride with Duraflex Tablet 10's can increase the risk of kidney problems, hyperkalemia(high potassium levels in blood), and high blood pressure.

How to manage the interaction:
There could be a possible interaction between Duraflex Tablet 10's and amiloride, but they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DiclofenacIndometacin
Severe
How does the drug interact with Duraflex Tablet 10's:
The combined use of Duraflex Tablet 10's and Indomethacin can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of Duraflex Tablet 10's and Indomethacin can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacFurosemide
Severe
How does the drug interact with Duraflex Tablet 10's:
Concomitant administration of Duraflex Tablet 10's and furosemide may decrease the therapeutic efficacy of furosemide and adversely affect renal function.

How to manage the interaction:
There may be a possible interaction between Duraflex Tablet 10's and furosemide, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms like nausea, dizziness, irregular heartbeats, altered blood pressure, tingling. Do not stop using any medications without first talking to your doctor.
DiclofenacPiroxicam
Severe
How does the drug interact with Duraflex Tablet 10's:
Taking Duraflex Tablet 10's and piroxicam can increase the risk of side effects such as ulcers, inflammation (redness, swelling), bleeding.

How to manage the interaction:
Co-administration of Duraflex Tablet 10's and Piroxicam can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.

  • Massages can also be helpful.

  • Avoid freezing and hot temperatures.

  • Avoid wearing tight-fitting clothes, instead, wear loose garments.

  • Rest well, get plenty of sleep.

  • To avoid developing pressure sores, change your position at least every two hours.

  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.

  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANALGESICS

Duraflex Tablet Substitute

Substitutes safety advice
  • Flexura D Tablet 10's

    21.60per tablet
  • Mobiswift-D Tablet 10's

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  • Myospas D Tablet 10's

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  • Flaminta Tablet 10's

    16.70per tablet
  • LYSOFLAM MR TABLET

    16.97per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Duraflex Tablet as it may cause increased drowsiness. It may also increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Duraflex Tablet ; your doctor will decide whether Duraflex Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Duraflex Tablet may cause drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Duraflex Tablet should not be given to children as the safety and effectiveness were not established.

FAQs

Duraflex Tablet is used to reduce and relieve pain due to muscle spasms (excessive tension in the muscles).
Duraflex Tablet is a combination of two drugs: Diclofenac (Nonsteroidal Anti-Inflammatory Drug) and metaxalone (skeletal muscle relaxant). Diclofenac works by blocking the action of certain chemical messengers that cause pain. Metaxalone works by blocking the pain sensations and nerve impulses. Together, Duraflex Tablet helps in relieving pain due to muscle spasm.
Duraflex Tablet may impair mental and/or physical abilities required for the performance of heavy tasks like operating machinery or driving a motor vehicle, especially when combined with alcohol or other CNS depressants (sleeping pills or antianxiety pills).
Do not take Duraflex Tablet for longer durations unless prescribed by the doctor as it might increase the risk of heart problems, liver problems and stomach bleeding/ulcer. Consult a doctor if you have any concerns.
To treat your condition effectually, continue taking Duraflex Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Duraflex Tablet .
Consult your doctor before taking Duraflex Tablet if you have stomach ulcers, bleeding problems, liver problems or heart problems.
Duraflex Tablet is a medication that relieves pain and reduces muscle spasms (muscle cramps). It contains two active ingredients: Diclofenac and Metaxalone.
The duration of taking Duraflex Tablet should be based on the specific medical condition being treated and the individual patient's needs. The treatment duration may vary, such as acute muscle spasms, chronic muscle spasms, or pain relief. However, it's essential to follow the specific guidance provided by your healthcare provider, as they will determine the appropriate duration of treatment based on your individual needs and medical history. By following their personalized advice, you can ensure safe and effective treatment.
Duraflex Tablet may cause nausea and vomiting. To help manage this, take your medication with food, eat small meals, and stay hydrated. You can also try ginger products to alleviate nausea. If your symptoms are severe or persistent, consult your doctor.
Using Duraflex Tablet can cause dizziness, especially when standing up quickly or changing positions. This is usually due to the metaxalone component, which can also cause lightheadedness, headache, and fatigue. To minimize dizziness, take your medication with food, avoid standing up too quickly, and change positions slowly. Additionally, avoid driving or operating heavy machinery if you experience dizziness. If your dizziness is severe or persistent, consult your doctor, as they may need to adjust your dosage or recommend alternative treatments to help manage your symptoms.
Duraflex Tablet should be used with caution if you have a history of bleeding problems, kidney or liver disease, stomach ulcers, heart failure, high blood pressure, or swelling. Additionally, use with caution if you have asthma, gout, diabetes, porphyria, or are an elderly patient. Do not take Diclofenac Metaxalone unless prescribed by a doctor who has carefully weighed the potential risks and benefits and determined it is safe for you to use, considering your individual health needs and medical history.
Yes, Duraflex Tablet can potentially damage kidneys, especially with long-term use or in people with pre-existing kidney disease. If you have kidney disease, use this medication cautiously and under medical supervision.
Taking more than the recommended dose of Duraflex Tablet can be dangerous. It can lead to serious side effects like stomach ulcers, kidney damage, and seizures. Always follow the prescribed dosage and consult your doctor if you have concerns. They will adjust the dosage if necessary to ensure your safety.
Duraflex Tablet should be stored in a cool, dry place away from sunlight. Keep Duraflex Tablet out of reach and out of sight to children.
Duraflex Tablet is not safe for use during pregnancy, particularly in the third trimester, as it may pose risks to the fetus. If you are pregnant or suspect you may be pregnant, consult your healthcare provider immediately. They will advise you on alternative, safer treatments for you and your baby. If you become pregnant while taking this medication, discontinue use immediately and seek medical guidance.
Only take Duraflex Tablet with any other medications, including blood pressure medications, if recommended by your doctor. Use it as directed by your doctor and follow their instructions carefully. They will help you safely manage your blood pressure and minimize potential interactions.
Duraflex Tablet is not recommended for use in children. Because the safety and efficacy of children have yet to be fully established. Please consult your doctor for proper diagnosis and safe treatment approaches.
Duraflex Tablet may cause common side effects such as stomach pain, nausea, vomiting, diarrhoea, dizziness and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Country of origin

India

Manufacturer/Marketer address

72/1, Tyagi Road, Dehradun (Uttarakhand)
Other Info - DUR0187

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