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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
LYSOFLAM MR TABLET is used to reduce and relieve pain due to muscle spasms (excessive tension in the muscles). It contains Diclofenac and Metaxalone, which works by blocking the effect of chemical messengers that cause pain and inflammation. Also, it blocks the nerve impulses and pain sensations in the brain, thereby helping to maintain muscle strength and relieving muscle spasms or stiffness. In some cases, it may cause common side effects such as stomach pain, nausea, vomiting, diarrhoea, dizziness and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Cachet Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About LYSOFLAM MR TABLET

LYSOFLAM MR TABLET is used to reduce and relieve pain due to muscle spasms (excessive tension in the muscles). Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms.

LYSOFLAM MR TABLET contains Diclofenac and Metaxalone. Diclofenac works by blocking the effect of chemical messengers that cause pain and inflammation. Metaxalone works by blocking the nerve impulses and pain sensations in the brain, thereby helping to maintain muscle strength and relieving muscle spasms or stiffness. Together, LYSOFLAM MR TABLET helps in relieving pain due to muscle spasms.

You are advised to take LYSOFLAM MR TABLET as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, LYSOFLAM MR TABLET may cause common side effects such as stomach pain, nausea, vomiting, diarrhoea, dizziness and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or breastfeeding. LYSOFLAM MR TABLET may cause drowsiness and dizziness, so drive only if you are alert. LYSOFLAM MR TABLET should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with LYSOFLAM MR TABLET as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of LYSOFLAM MR TABLET

Treatment of Pain due to muscle spasm.

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Medicinal Benefits

LYSOFLAM MR TABLET is a combination of two drugs: Diclofenac and Metaxalone. Diclofenac is an NSAID (Non-Steroidal Anti-Inflammatory Drug), and metaxalone is a skeletal muscle relaxant. LYSOFLAM MR TABLET is used to reduce and relieve pain due to muscle spasms (excessive tension in the muscles). Diclofenac works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Metaxalone works on the centres of the spinal cord and brain, thereby helping to maintain muscle strength and relieving muscle spasms or stiffness. Together, LYSOFLAM MR TABLET helps in relieving pain due to muscle spasms.

How LYSOFLAM MR TABLET Works

LYSOFLAM MR TABLET contains Diclofenac and Metaxalone. Diclofenac works by blocking the effect of chemical messengers that cause pain and inflammation. Metaxalone works by blocking the nerve impulses and pain sensations in the brain, thereby helping to maintain muscle strength and relieving muscle spasms or stiffness. Together, LYSOFLAM MR TABLET helps in relieving pain due to muscle spasms.

Storage

Store in a cool and dry place away from sunlight

Side Effects of LYSOFLAM MR TABLET

  • Stomach pain
  • Nausea
  • Vomiting
  • Diarrhoea
  • Dizziness
  • Headache

What if I have taken an overdose of LYSOFLAM MR TABLET

Do not take more than the prescribed dose of LYSOFLAM MR TABLET as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

If you have had any recent heart surgery, do not take LYSOFLAM MR TABLET unless advised by the doctor as it may increase the risk of fatal heart attack or stroke. Do not take LYSOFLAM MR TABLET if you are allergic to any of its components, have severe heart failure, or have suffered bleeding problems such as bleeding from the stomach or bowels while taking any painkillers. Inform your doctor before taking LYSOFLAM MR TABLET if you have/had high blood pressure, heart problems, high cholesterol, diabetes, asthma, liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. LYSOFLAM MR TABLET may cause drowsiness and dizziness, so drive only if you are alert. LYSOFLAM MR TABLET should not be given to children as safety has not been established. Avoid consuming alcohol along with LYSOFLAM MR TABLET as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Stop taking LYSOFLAM MR TABLET and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach such as blood in stools. Do not take any other NSAIDs for pain relief along with LYSOFLAM MR TABLET unless prescribed. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
DiclofenacEnoxaparin
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with LYSOFLAM MR TABLET:
Co-administration of LYSOFLAM MR TABLET with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with LYSOFLAM MR TABLET is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacEnoxaparin
Severe
How does the drug interact with LYSOFLAM MR TABLET:
Taking LYSOFLAM MR TABLET with Enoxaparin can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between LYSOFLAM MR TABLET and Enoxaparin, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
DiclofenacLeflunomide
Severe
How does the drug interact with LYSOFLAM MR TABLET:
Co administration of LYSOFLAM MR TABLET with Leflunomide may result in liver problems.

How to manage the interaction:
Co-administration of LYSOFLAM MR TABLET and Leflunomide can lead to an interaction; it can be taken if advised by your doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, or yellowing of the skin or eyes. Do not stop using any medication without consulting your doctor.
DiclofenacSulindac
Severe
How does the drug interact with LYSOFLAM MR TABLET:
Co-administration of LYSOFLAM MR TABLET and sulindac can increase the risk of side effects.

How to manage the interaction:
Although there is a interaction between LYSOFLAM MR TABLET and sulindac, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacKetorolac
Severe
How does the drug interact with LYSOFLAM MR TABLET:
Coadministration of LYSOFLAM MR TABLET and Ketorolac can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulceration.

How to manage the interaction:
Co-administration of LYSOFLAM MR TABLET and Ketorolac can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacLomitapide
Severe
How does the drug interact with LYSOFLAM MR TABLET:
Taking LYSOFLAM MR TABLET with Lomitapide will have an additive effect and may cause liver problems.

How to manage the interaction:
There may be a possible interaction between LYSOFLAM MR TABLET and Lomitapide, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
DiclofenacRamucirumab
Severe
How does the drug interact with LYSOFLAM MR TABLET:
Co-administration of LYSOFLAM MR TABLET and Ramucirumab can cause bleeding and ulcers.

How to manage the interaction:
Co-administration of LYSOFLAM MR TABLET and Ramucirumab can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacPanobinostat
Severe
How does the drug interact with LYSOFLAM MR TABLET:
Taking LYSOFLAM MR TABLET with Panobinostat can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between LYSOFLAM MR TABLET and Panobinostat, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or have other signs of bleeding like dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.
DiclofenacIndometacin
Severe
How does the drug interact with LYSOFLAM MR TABLET:
The combined use of LYSOFLAM MR TABLET and Indomethacin can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of LYSOFLAM MR TABLET and Indomethacin can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacNaproxen
Severe
How does the drug interact with LYSOFLAM MR TABLET:
Coadministration of LYSOFLAM MR TABLET and Naproxen can increase the risk or severity of side effects.

How to manage the interaction:
Taking LYSOFLAM MR TABLET and Naproxen together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.

  • Massages can also be helpful.

  • Avoid freezing and hot temperatures.

  • Avoid wearing tight-fitting clothes, instead, wear loose garments.

  • Rest well, get plenty of sleep.

  • To avoid developing pressure sores, change your position at least every two hours.

  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.

  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANALGESICS

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Alcohol

Unsafe

Avoid consumption of alcohol while taking LYSOFLAM MR TABLET as it may cause increased drowsiness. It may also increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking LYSOFLAM MR TABLET; your doctor will decide whether LYSOFLAM MR TABLET can be taken by breastfeeding mothers or not.

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Driving

Caution

LYSOFLAM MR TABLET may cause drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

LYSOFLAM MR TABLET should not be given to children as the safety and effectiveness were not established.

FAQs

LYSOFLAM MR TABLET is used to reduce and relieve pain due to muscle spasms (excessive tension in the muscles).
LYSOFLAM MR TABLET is a combination of two drugs: Diclofenac (Nonsteroidal Anti-Inflammatory Drug) and metaxalone (skeletal muscle relaxant). Diclofenac works by blocking the action of certain chemical messengers that cause pain. Metaxalone works by blocking the pain sensations and nerve impulses. Together, LYSOFLAM MR TABLET helps in relieving pain due to muscle spasm.
LYSOFLAM MR TABLET may impair mental and/or physical abilities required for the performance of heavy tasks like operating machinery or driving a motor vehicle, especially when combined with alcohol or other CNS depressants (sleeping pills or antianxiety pills).
Do not take LYSOFLAM MR TABLET for longer durations unless prescribed by the doctor as it might increase the risk of heart problems, liver problems and stomach bleeding/ulcer. Consult a doctor if you have any concerns.
To treat your condition effectually, continue taking LYSOFLAM MR TABLET for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking LYSOFLAM MR TABLET.
Consult your doctor before taking LYSOFLAM MR TABLET if you have stomach ulcers, bleeding problems, liver problems or heart problems.
LYSOFLAM MR TABLET is a medication that relieves pain and reduces muscle spasms (muscle cramps). It contains two active ingredients: Diclofenac and Metaxalone.
The duration of taking LYSOFLAM MR TABLET should be based on the specific medical condition being treated and the individual patient's needs. The treatment duration may vary, such as acute muscle spasms, chronic muscle spasms, or pain relief. However, it's essential to follow the specific guidance provided by your healthcare provider, as they will determine the appropriate duration of treatment based on your individual needs and medical history. By following their personalized advice, you can ensure safe and effective treatment.
LYSOFLAM MR TABLET may cause nausea and vomiting. To help manage this, take your medication with food, eat small meals, and stay hydrated. You can also try ginger products to alleviate nausea. If your symptoms are severe or persistent, consult your doctor.
Using LYSOFLAM MR TABLET can cause dizziness, especially when standing up quickly or changing positions. This is usually due to the metaxalone component, which can also cause lightheadedness, headache, and fatigue. To minimize dizziness, take your medication with food, avoid standing up too quickly, and change positions slowly. Additionally, avoid driving or operating heavy machinery if you experience dizziness. If your dizziness is severe or persistent, consult your doctor, as they may need to adjust your dosage or recommend alternative treatments to help manage your symptoms.
LYSOFLAM MR TABLET should be used with caution if you have a history of bleeding problems, kidney or liver disease, stomach ulcers, heart failure, high blood pressure, or swelling. Additionally, use with caution if you have asthma, gout, diabetes, porphyria, or are an elderly patient. Do not take Diclofenac Metaxalone unless prescribed by a doctor who has carefully weighed the potential risks and benefits and determined it is safe for you to use, considering your individual health needs and medical history.
Yes, LYSOFLAM MR TABLET can potentially damage kidneys, especially with long-term use or in people with pre-existing kidney disease. If you have kidney disease, use this medication cautiously and under medical supervision.
Taking more than the recommended dose of LYSOFLAM MR TABLET can be dangerous. It can lead to serious side effects like stomach ulcers, kidney damage, and seizures. Always follow the prescribed dosage and consult your doctor if you have concerns. They will adjust the dosage if necessary to ensure your safety.
LYSOFLAM MR TABLET should be stored in a cool, dry place away from sunlight. Keep LYSOFLAM MR TABLET out of reach and out of sight to children.
LYSOFLAM MR TABLET is not safe for use during pregnancy, particularly in the third trimester, as it may pose risks to the fetus. If you are pregnant or suspect you may be pregnant, consult your healthcare provider immediately. They will advise you on alternative, safer treatments for you and your baby. If you become pregnant while taking this medication, discontinue use immediately and seek medical guidance.
Only take LYSOFLAM MR TABLET with any other medications, including blood pressure medications, if recommended by your doctor. Use it as directed by your doctor and follow their instructions carefully. They will help you safely manage your blood pressure and minimize potential interactions.
LYSOFLAM MR TABLET is not recommended for use in children. Because the safety and efficacy of children have yet to be fully established. Please consult your doctor for proper diagnosis and safe treatment approaches.
LYSOFLAM MR TABLET may cause common side effects such as stomach pain, nausea, vomiting, diarrhoea, dizziness and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Country of origin

INDIA

Manufacturer/Marketer address

Exhibition Road, P.S. Gandhi Maidan, Patna – 800001
Other Info - LYS0017

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