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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Oct 9, 2024 | 12:36 PM IST
Doxibrit 100 mg Injection 1's is an antibiotic medicine used to treat bacterial infections such as urinary tract infections, intestinal infections, respiratory infections, eye infections, skin infections, sexually transmitted infections, and periodontitis. This medicine contains doxycycline which works by inhibiting the protein synthesis of the bacterial cell and thereby helps fight infection-causing bacteria. This medicine is not effective for treating viral infections. Common side effects include pain, itching, swelling or redness at the site of injection, nausea, vomiting, or diarrhoea.
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Prescription drug

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Manufacturer/Marketer

Biocrit Healthcare Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Doxibrit 100 mg Injection 1's

Doxibrit 100 mg Injection 1's belongs to a group of medications called tetracycline antibiotics used to treat bacterial infections such as urinary tract infections, intestinal infections, respiratory infections, eye infections, skin infections, sexually transmitted infections (gonorrhoea, syphilis), and gum infections (periodontitis). Besides this, Doxibrit 100 mg Injection 1's may also be used to treat or prevent anthrax.

Doxibrit 100 mg Injection 1's contains 'Doxycycline' which stops the growth of bacteria by preventing the synthesis of essential proteins necessary for their survival. Thereby, Doxibrit 100 mg Injection 1's helps treat bacterial infections. It is a broad-spectrum antibiotic which is effective against both gram-negative and gram-positive bacteria.

Doxibrit 100 mg Injection 1's will be administered by a healthcare professional; do not self-administer. In some cases, Doxibrit 100 mg Injection 1's may cause pain, itching, swelling or redness at the site of injection, nausea, vomiting, or diarrhoea. Most of these side effects of Doxibrit 100 mg Injection 1's do not require medical attention and gradually resolve over time. Please consult your doctor if these side effects become troublesome.

Do not take Doxibrit 100 mg Injection 1's if you are allergic to any of the components. Consult your doctor if you are pregnant or breastfeeding. Use of Doxibrit 100 mg Injection 1's during tooth development (last half of pregnancy, infancy, and in children below 8 years) may cause teeth staining (yellow-grey-brown). Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Uses of Doxibrit 100 mg Injection 1's

Treatment of Bacterial infections

Medicinal Benefits

Doxibrit 100 mg Injection 1's belongs to the class of medicines called tetracycline antibiotics which is effective against a wide range of bacteria, including gram-negative, gram-positive bacteria, anaerobes, and some parasites. It is used to treat respiratory tract infections (influenza, pneumonia), genitourinary infections (syphilis, gonorrhoea), anthrax infection, sinuses, eye, and skin infections. Besides this, it is also indicated in the tick-borne infections (typhus fever) caused by the Rickettsia group of bacteria like typhus fever. Off-label, usage includes the prevention of malaria and the treatment of acne.

Directions for Use

Doxibrit 100 mg Injection 1's will be administered by a qualified healthcare professional. Kindly do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Doxibrit 100 mg Injection 1's

  • Pain, itching, swelling or redness at the site of injection
  • Nausea
  • Vomiting
  • Diarrhoea

Drug Warnings

Do not take Doxibrit 100 mg Injection 1's if you are allergic to any of its contents. Inform your doctor if you have lupus, or if you are pregnant or breastfeeding.  Use of Doxibrit 100 mg Injection 1's during tooth development (last half of pregnancy, infancy, and in children below 8 years) may cause teeth staining (yellow-grey-brown). Consult your doctor if you experience any skin reactions, fever,  muscle, or joint problems.

Drug Interactions

Drug-Drug Interactions: Doxibrit 100 mg Injection 1's may interact with retinoid medications taken by mouth (acitretin, isotretinoin), blood thinners (warfarin), heart disease medicine (digoxin), anti-seizure medications (phenytoin, carbamazepine), antacids containing aluminium, calcium, or magnesium, bismuth subsalicylate, iron supplements, and oral birth control pills. 

Drug-Food Interactions: Food containing calcium and iron should be avoided within 2 hours of Doxibrit 100 mg Injection 1's as it may affect Doxibrit 100 mg Injection 1's effectiveness.

Drug-Disease Interactions: Inform your doctor if you have kidney problems, liver problems, swollen food pipe (esophagitis), lupus disease (an autoimmune disease), or muscle disease (myasthenia gravis).

Drug-Drug Interactions Checker List

  • ACITRETIN
  • ISOTRETINOIN
  • WARFARIN
  • DIGOXIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • ALUMINIUM
  • CALCIUM
  • MAGNESIUM
  • BISMUTH SUBSALICYLATE

Habit Forming

No

Diet & Lifestyle Advise

  • It would be best to take probiotics after completing the full course of Doxibrit 100 mg Injection 1's to restore healthy bacteria in the intestine that may have been killed due to the usage of antibiotics. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yogurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Whole-grain bread, and brown rice, should be included in your diet.
  • Avoid taking too much calcium enriched foods and drinks as it might affect the working of Doxibrit 100 mg Injection 1's.
  • Avoid intake of alcoholic beverages with Doxibrit 100 mg Injection 1's as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid Doxibrit 100 mg Injection 1's in fighting off infections.

Special Advise

  • Wear sunglasses and sunscreen when you go out in the sun as Doxibrit 100 mg Injection 1's can make your skin sensitive to light.
  • Maintain a gap of 2 hours between Doxibrit 100 mg Injection 1's and iron supplements and antacids as taking them together might affect the working of Doxibrit 100 mg Injection 1's.
  • Doxibrit 100 mg Injection 1's might affect certain lab tests, inform the person doing the tests that you are taking Doxibrit 100 mg Injection 1's.

Disease/Condition Glossary

Bacterial infection: A bacterial infection is a condition in which harmful bacteria enter, multiply and infect the body. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms like fever, chills, and fatigue. Anyone can become infected with a bacterial infection. But, people with a weak immune system or taking immunosuppressive medicine are more prone to bacterial infection.

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Alcohol

Caution

It is not known if alcohol affects Doxibrit 100 mg Injection 1's. Please consult your doctor if you have any concerns.

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Pregnancy

Unsafe

Doxibrit 100 mg Injection 1's belongs to pregnancy category D. There are no adequate and well-controlled studies on the use of Doxibrit 100 mg Injection 1's in pregnant women. In some cases, taking Doxibrit 100 mg Injection 1's during pregnancy may affect tooth and bone development in the unborn baby. So, if you are pregnant or planning for pregnancy contact the doctor before using Doxibrit 100 mg Injection 1's.

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Breast Feeding

Caution

Doxibrit 100 mg Injection 1's is excreted in the breast milk. However, the extent of absorption of Doxibrit 100 mg Injection 1's by the breastfed infant is not known. Hence, the nursing mother should consult the doctor before using Doxibrit 100 mg Injection 1's.

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Driving

Caution

It is not known if Doxibrit 100 mg Injection 1's affects your ability to drive. Drive or operate machinery only if you are alert.

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Liver

Caution

Doxibrit 100 mg Injection 1's is to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Safe if prescribed

At the recommended doses, Doxibrit 100 mg Injection 1's is safe to use in patients with kidney disease if prescribed by a doctor.

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Children

Caution

Use of Doxibrit 100 mg Injection 1's during tooth development in infants and children below 8 years of age may cause permanent staining of teeth (yellow-grey-brown). So, it is not recommended for children below 8 years of age.

Country of origin

India

Manufacturer/Marketer address

KONARK POORAM HOUSING SOCIETY PH III, BLDG U-2 SR NO 7 KONDHWA PUNE Pune MH 411048 IN
Other Info - DOX0604

Author Details

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FAQs

Doxibrit 100 mg Injection 1's belongs to a group of medications called tetracycline antibiotics used to treat bacterial infections such as urinary tract infections, intestinal infections, respiratory infections, eye infections, skin infections, sexually transmitted infections (gonorrhoea, syphilis), and gum infections (periodontitis). Besides this, Doxibrit 100 mg Injection 1's may also be used to treat or prevent anthrax.
Doxibrit 100 mg Injection 1's stops the growth of bacteria by preventing the synthesis of essential proteins necessary for their survival. Thereby, Doxibrit 100 mg Injection 1's helps treat bacterial infections.
No, Doxibrit 100 mg Injection 1's should not be stopped even if you feel better as it is an antibiotic medication and completing the full course is necessary; otherwise, the infection might re-appear in a more severe form and will also become difficult to treat due to antibiotic resistance.
If you are taking Doxibrit 100 mg Injection 1's, avoid taking antacids containing aluminium, calcium or magnesium or other drugs containing these cations; oral zinc, iron salts or bismuth preparations within 2 hours of consumption of Doxibrit 100 mg Injection 1's as they may affect the absorption of Doxibrit 100 mg Injection 1's. Avoid taking dairy products within 2 hours of taking Doxibrit 100 mg Injection 1's as they may also impair the absorption of Doxibrit 100 mg Injection 1's.
Use of Doxibrit 100 mg Injection 1's during tooth development (last half of pregnancy, infancy, and in children below the age of 8 years) may cause permanent staining of teeth (yellow-grey-brown). So, it is not recommended for pregnant women, breastfeeding mothers, and children below 8 years of age.
Doxibrit 100 mg Injection 1's may make your skin sensitive to sunlight. So, apply sunscreen while going out and wear protective clothing and sunglasses. Avoid prolonged and unnecessary exposure to sunlight.
Doxibrit 100 mg Injection 1's may lower the effectiveness of hormonal contraceptives such as birth control pills, rings, patches, or injections. Consult your doctor if you have any concerns, your doctor may advise regarding other forms of contraception.
Doxibrit 100 mg Injection 1's does not completely prevent malaria caused by P. falciparum as Doxibrit 100 mg Injection 1's is given as a prophylactic regimen (protection) whenever anyone enters a malaria-prone area.

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