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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Plugdox 100 mg Injection is an antibiotic medicine used to treat bacterial infections such as urinary tract infections, intestinal infections, respiratory infections, eye infections, skin infections, sexually transmitted infections, and periodontitis. This medicine contains doxycycline which works by inhibiting the protein synthesis of the bacterial cell and thereby helps fight infection-causing bacteria. This medicine is not effective for treating viral infections. Common side effects include pain, itching, swelling or redness at the site of injection, nausea, vomiting, or diarrhoea.
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Composition :

DOXYCYCLINE-100MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Plugdox 100 mg Injection

Plugdox 100 mg Injection belongs to a group of medications called tetracycline antibiotics used to treat bacterial infections such as urinary tract infections, intestinal infections, respiratory infections, eye infections, skin infections, sexually transmitted infections (gonorrhoea, syphilis), and gum infections (periodontitis). Besides this, Plugdox 100 mg Injection may also be used to treat or prevent anthrax.

Plugdox 100 mg Injection contains 'Doxycycline' which stops the growth of bacteria by preventing the synthesis of essential proteins necessary for their survival. Thereby, Plugdox 100 mg Injection helps treat bacterial infections. It is a broad-spectrum antibiotic which is effective against both gram-negative and gram-positive bacteria.

Plugdox 100 mg Injection will be administered by a healthcare professional; do not self-administer. In some cases, Plugdox 100 mg Injection may cause pain, itching, swelling or redness at the site of injection, nausea, vomiting, or diarrhoea. Most of these side effects of Plugdox 100 mg Injection do not require medical attention and gradually resolve over time. Please consult your doctor if these side effects become troublesome.

Do not take Plugdox 100 mg Injection if you are allergic to any of the components. Consult your doctor if you are pregnant or breastfeeding. Use of Plugdox 100 mg Injection during tooth development (last half of pregnancy, infancy, and in children below 8 years) may cause teeth staining (yellow-grey-brown). Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Uses of Plugdox 100 mg Injection

Treatment of Bacterial infections

Directions for Use

Plugdox 100 mg Injection will be administered by a qualified healthcare professional. Kindly do not self-administer.

Medicinal Benefits

Plugdox 100 mg Injection belongs to the class of medicines called tetracycline antibiotics which is effective against a wide range of bacteria, including gram-negative, gram-positive bacteria, anaerobes, and some parasites. It is used to treat respiratory tract infections (influenza, pneumonia), genitourinary infections (syphilis, gonorrhoea), anthrax infection, sinuses, eye, and skin infections. Besides this, it is also indicated in the tick-borne infections (typhus fever) caused by the Rickettsia group of bacteria like typhus fever. Off-label, usage includes the prevention of malaria and the treatment of acne.

How Plugdox 100 mg Injection Works

Plugdox 100 mg Injection contains 'Doxycycline' which stops the growth of bacteria by preventing the synthesis of essential proteins necessary for their survival. Thereby, Plugdox 100 mg Injection helps treat bacterial infections. It is a broad-spectrum antibiotic which is effective against both gram-negative and gram-positive bacteria.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Plugdox 100 mg Injection

  • Pain, itching, swelling or redness at the site of injection
  • Nausea
  • Vomiting
  • Diarrhoea

What if I have taken an overdose of Plugdox 100 mg Injection

Plugdox 100 mg Injection is administered by a healthcare professional in a hospital setting. Hence, the chances of overdose are less. Overdose can cause nausea, vomiting, diarrhea, photosensitivity (skin reaction to the sun), indigestion, loss of appetite and mild rash. Your doctor may initiate necessary treatment if an overdose is suspected.

Drug Warnings

Do not take Plugdox 100 mg Injection if you are allergic to any of its contents. Inform your doctor if you have lupus, or if you are pregnant or breastfeeding.  Use of Plugdox 100 mg Injection during tooth development (last half of pregnancy, infancy, and in children below 8 years) may cause teeth staining (yellow-grey-brown). Consult your doctor if you experience any skin reactions, fever,  muscle, or joint problems.

Drug-Drug Interactions

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DoxycyclineTretinoin
Critical
DoxycyclineIsotretinoin
Critical

Drug-Drug Interactions

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DoxycyclineTretinoin
Critical
How does the drug interact with Plugdox 100 mg Injection 1's:
Coadministration of Tretinoin with Plugdox 100 mg Injection 1's can increase the risk of side effects like vision problems.

How to manage the interaction:
Taking Tretinoin with Plugdox 100 mg Injection 1's is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden headache, nausea, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
DoxycyclineIsotretinoin
Critical
How does the drug interact with Plugdox 100 mg Injection 1's:
Taking isotretinoin with Plugdox 100 mg Injection 1's may increase the risk of a rare condition called pseudotumor cerebri (increased pressure in the brain).

How to manage the interaction:
Although taking isotretinoin and Plugdox 100 mg Injection 1's together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, nausea, vomiting, and visual disturbances, consult a doctor. Do not stop using any medications without consulting doctor.
DoxycyclineEtretinate
Critical
How does the drug interact with Plugdox 100 mg Injection 1's:
Taking Plugdox 100 mg Injection 1's with etretinate may increase the risk of vision problems.

How to manage the interaction:
Taking Etretinate with Plugdox 100 mg Injection 1's is not recommended, but can be taken if prescribed by a doctor. However, consult a doctor if you experience headache, nausea, vomiting, and visual disturbances. Do not discontinue any medication without consulting a doctor.
DoxycyclineAcitretin
Critical
How does the drug interact with Plugdox 100 mg Injection 1's:
Coadministration of Acitretin with Plugdox 100 mg Injection 1's can increase the risk and severity of vision problems.

How to manage the interaction:
Taking Acitretin with Plugdox 100 mg Injection 1's together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience headaches, nausea, vomiting, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DoxycyclineCalcium acetate
Severe
How does the drug interact with Plugdox 100 mg Injection 1's:
Co-administration of Plugdox 100 mg Injection 1's with calcium acetate can reduce its effectiveness.

How to manage the interaction:
Although there is an interaction between calcium acetate and Plugdox 100 mg Injection 1's, it can be taken together if prescribed by a doctor. It is adviced to take Plugdox 100 mg Injection 1's 2 hrs before or 6 hours after taking calcium acetate. Do not stop using any medications without talking to a doctor.
DoxycyclineAminolevulinic acid
Severe
How does the drug interact with Plugdox 100 mg Injection 1's:
Co-administration of aminolevulinic acid with Plugdox 100 mg Injection 1's may increase the risk of sunburn.

How to manage the interaction:
Co-administration of Plugdox 100 mg Injection 1's with Aminolevulinic acid can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice that your skin is very sensitive to sunlight or if you have a sunburn, it's important to contact your doctor right away. Do not stop using any medications without first talking to your doctor.
DoxycyclineSodium citrate
Severe
How does the drug interact with Plugdox 100 mg Injection 1's:
Coadministration of Sodium Citrate with Plugdox 100 mg Injection 1's can reduce the effectiveness of Plugdox 100 mg Injection 1's.

How to manage the interaction:
Although taking Sodium Citrate with Plugdox 100 mg Injection 1's can possibly result in decreased efficacy, they can be taken together if prescribed by a doctor. It is advised to separate sodium citrate and Plugdox 100 mg Injection 1's by three to four hours. Do not stop using any medications without consulting a doctor.
DoxycyclineFerrous fumarate
Severe
How does the drug interact with Plugdox 100 mg Injection 1's:
Taking Plugdox 100 mg Injection 1's with ferrous fumarate can reduce the levels and effects of Plugdox 100 mg Injection 1's.

How to manage the interaction:
Although taking ferrous fumarate and Plugdox 100 mg Injection 1's possibly results in an interaction, they can be taken together as advised by your doctor. However, consult a doctor if you experience any unusual symptoms. Do not stop using any medications without consulting a doctor.
DoxycyclineKetoconazole
Severe
How does the drug interact with Plugdox 100 mg Injection 1's:
Coadministration of Ketoconazole and Plugdox 100 mg Injection 1's may increase the risk of liver problems.

How to manage the interaction:
Although taking Plugdox 100 mg Injection 1's with Ketoconazole can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience any symptoms such as joint pain or swelling, skin rash, itching, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue using any medications without consulting a doctor.
DoxycyclineOxacillin
Severe
How does the drug interact with Plugdox 100 mg Injection 1's:
Taking Plugdox 100 mg Injection 1's with Oxacillin together may decrease the effectiveness of Plugdox 100 mg Injection 1's.

How to manage the interaction:
Although taking Plugdox 100 mg Injection 1's with Oxacillin can result in decreased efficacy, they can be taken together if prescribed by your doctor. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to take probiotics after completing the full course of Plugdox 100 mg Injection to restore healthy bacteria in the intestine that may have been killed due to the usage of antibiotics. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yogurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Whole-grain bread, and brown rice, should be included in your diet.
  • Avoid taking too much calcium enriched foods and drinks as it might affect the working of Plugdox 100 mg Injection.
  • Avoid intake of alcoholic beverages with Plugdox 100 mg Injection as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid Plugdox 100 mg Injection in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Plugdox 100 mg Injection Substitute

Substitutes safety advice
  • Doxy T 100 Capsule 8's

    by AYUR

    4.50per tablet
  • Minicycline Capsule 10's

    3.11per tablet
  • Codox Capsule 10's

    3.11per tablet
  • Pepdox 100 Capsule 10's

    9.45per tablet
  • Dox-100 Tablet 8's

    3.94per tablet
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Alcohol

Caution

It is not known if alcohol affects Plugdox 100 mg Injection. Please consult your doctor if you have any concerns.

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Pregnancy

Unsafe

Plugdox 100 mg Injection belongs to pregnancy category D. There are no adequate and well-controlled studies on the use of Plugdox 100 mg Injection in pregnant women. In some cases, taking Plugdox 100 mg Injection during pregnancy may affect tooth and bone development in the unborn baby. So, if you are pregnant or planning for pregnancy contact the doctor before using Plugdox 100 mg Injection.

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Breast Feeding

Caution

Plugdox 100 mg Injection is excreted in the breast milk. However, the extent of absorption of Plugdox 100 mg Injection by the breastfed infant is not known. Hence, the nursing mother should consult the doctor before using Plugdox 100 mg Injection.

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Driving

Caution

It is not known if Plugdox 100 mg Injection affects your ability to drive. Drive or operate machinery only if you are alert.

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Liver

Caution

Plugdox 100 mg Injection is to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Safe if prescribed

At the recommended doses, Plugdox 100 mg Injection is safe to use in patients with kidney disease if prescribed by a doctor.

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Children

Caution

Use of Plugdox 100 mg Injection during tooth development in infants and children below 8 years of age may cause permanent staining of teeth (yellow-grey-brown). So, it is not recommended for children below 8 years of age.

FAQs

Plugdox 100 mg Injection belongs to a group of medications called tetracycline antibiotics used to treat bacterial infections such as urinary tract infections, intestinal infections, respiratory infections, eye infections, skin infections, sexually transmitted infections (gonorrhoea, syphilis), and gum infections (periodontitis). Besides this, Plugdox 100 mg Injection may also be used to treat or prevent anthrax.
Plugdox 100 mg Injection stops the growth of bacteria by preventing the synthesis of essential proteins necessary for their survival. Thereby, Plugdox 100 mg Injection helps treat bacterial infections.
No, Plugdox 100 mg Injection should not be stopped even if you feel better as it is an antibiotic medication and completing the full course is necessary; otherwise, the infection might re-appear in a more severe form and will also become difficult to treat due to antibiotic resistance.
If you are taking Plugdox 100 mg Injection, avoid taking antacids containing aluminium, calcium or magnesium or other drugs containing these cations; oral zinc, iron salts or bismuth preparations within 2 hours of consumption of Plugdox 100 mg Injection as they may affect the absorption of Plugdox 100 mg Injection. Avoid taking dairy products within 2 hours of taking Plugdox 100 mg Injection as they may also impair the absorption of Plugdox 100 mg Injection.
Use of Plugdox 100 mg Injection during tooth development (last half of pregnancy, infancy, and in children below the age of 8 years) may cause permanent staining of teeth (yellow-grey-brown). So, it is not recommended for pregnant women, breastfeeding mothers, and children below 8 years of age.
Plugdox 100 mg Injection may make your skin sensitive to sunlight. So, apply sunscreen while going out and wear protective clothing and sunglasses. Avoid prolonged and unnecessary exposure to sunlight.
Plugdox 100 mg Injection may lower the effectiveness of hormonal contraceptives such as birth control pills, rings, patches, or injections. Consult your doctor if you have any concerns, your doctor may advise regarding other forms of contraception.
Plugdox 100 mg Injection does not completely prevent malaria caused by P. falciparum as Plugdox 100 mg Injection is given as a prophylactic regimen (protection) whenever anyone enters a malaria-prone area.

Country of origin

India

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - PLU0048

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